JP2003055360A - Ｃ１０エステル置換タキサン - Google Patents

Ｃ１０エステル置換タキサン

Info

Publication number
JP2003055360A
JP2003055360A JP2001233149A JP2001233149A JP2003055360A JP 2003055360 A JP2003055360 A JP 2003055360A JP 2001233149 A JP2001233149 A JP 2001233149A JP 2001233149 A JP2001233149 A JP 2001233149A JP 2003055360 A JP2003055360 A JP 2003055360A
Authority
JP
Japan
Prior art keywords
pyridyl
furyl
thienyl
taxane
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001233149A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003055360A5 (enExample
Inventor
Robert A Holton
ロバート・エイ・ホルトン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Florida State University Research Foundation Inc
Original Assignee
Florida State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002354471A priority Critical patent/CA2354471A1/en
Application filed by Florida State University Research Foundation Inc filed Critical Florida State University Research Foundation Inc
Priority to JP2001233149A priority patent/JP2003055360A/ja
Priority to EP01118728A priority patent/EP1285920A1/en
Publication of JP2003055360A publication Critical patent/JP2003055360A/ja
Publication of JP2003055360A5 publication Critical patent/JP2003055360A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
JP2001233149A 2001-07-31 2001-08-01 Ｃ１０エステル置換タキサン Pending JP2003055360A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002354471A CA2354471A1 (en) 2001-07-31 2001-07-31 C10 ester substituted taxanes
JP2001233149A JP2003055360A (ja) 2001-07-31 2001-08-01 Ｃ１０エステル置換タキサン
EP01118728A EP1285920A1 (en) 2001-07-31 2001-08-06 C10 Ester sustituted taxanes as antitumor agents

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002354471A CA2354471A1 (en) 2001-07-31 2001-07-31 C10 ester substituted taxanes
JP2001233149A JP2003055360A (ja) 2001-07-31 2001-08-01 Ｃ１０エステル置換タキサン
EP01118728A EP1285920A1 (en) 2001-07-31 2001-08-06 C10 Ester sustituted taxanes as antitumor agents

Publications (2)

Publication Number Publication Date
JP2003055360A true JP2003055360A (ja) 2003-02-26
JP2003055360A5 JP2003055360A5 (enExample) 2008-09-18

Family

ID=27808193

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001233149A Pending JP2003055360A (ja) 2001-07-31 2001-08-01 Ｃ１０エステル置換タキサン

Country Status (3)

Country Link
EP (1) EP1285920A1 (enExample)
JP (1) JP2003055360A (enExample)
CA (1) CA2354471A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007522236A (ja) * 2004-02-13 2007-08-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロペンチルエステル置換タキサン

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1810968A3 (en) * 2003-09-25 2007-08-08 Tapestry Pharmaceuticals, Inc. 9, 10-a, a-OH-taxane analogs and methods for production thereof
JP4874102B2 (ja) 2003-09-25 2012-02-15 タペストリー ファーマシューティカルズ インコーポレーテッド ９，１０−α，α−ＯＨ−タキサンアナログおよびその生成のための方法
CN1303077C (zh) 2004-01-16 2007-03-07 桂林晖昂生化药业有限责任公司 合成紫杉烷的制备工艺
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
WO2008121476A1 (en) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
WO2008109360A1 (en) 2007-02-28 2008-09-12 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
CN101274924B (zh) * 2007-03-27 2010-11-10 中国科学院大连化学物理研究所 一种制备紫杉醇及其衍生物的方法

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0534709A1 (en) * 1991-09-23 1993-03-31 Florida State University Substituted taxanes as antitumour agents
WO1993018018A1 (en) * 1992-03-13 1993-09-16 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
WO1994007880A1 (fr) * 1992-10-05 1994-04-14 Rhone-Poulenc Rorer S.A. Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent
WO1995004154A1 (en) * 1993-07-27 1995-02-09 Nippon Steel Corporation Process for producing taxol and its analogues using microorganisms
WO1997032578A1 (en) * 1996-03-04 1997-09-12 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
WO1997044063A2 (en) * 1996-05-22 1997-11-27 Neuromedica, Inc. Dha-pharmaceutical agent conjugates
WO1997044026A1 (en) * 1996-05-22 1997-11-27 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
WO1998002426A1 (en) * 1996-07-15 1998-01-22 Kabushiki Kaisha Yakult Honsha Taxane derivatives and drugs containing the same
WO1999014209A1 (en) * 1997-09-17 1999-03-25 Kabushiki Kaisha Yakult Honsha New taxane derivatives
WO1999032473A1 (en) * 1997-12-19 1999-07-01 Kabushiki Kaisha Yakult Honsha Taxane derivatives
WO2000053592A1 (en) * 1999-03-05 2000-09-14 Asahi Kasei Kabushiki Kaisha Osteogenesis promoters
WO2001057032A1 (en) * 2000-02-02 2001-08-09 Florida State University Research Foundation, Inc. C10 ester substituted taxanes as antitumor agents
WO2001068089A1 (en) * 2000-03-17 2001-09-20 Indena S.P.A. Condensation derivatives of thiocolchicine and baccatin as antitumor agents
JP2003521545A (ja) * 2000-02-02 2003-07-15 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 改良された溶解性を有するタキサン製剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US102404A (en) * 1870-04-26 Improvement in alphabetical indexes
WO1996013495A1 (en) * 1994-10-28 1996-05-09 The Research Foundation Of State University Of New York Taxoid derivatives, their preparation and their use as antitumor agents

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0534709A1 (en) * 1991-09-23 1993-03-31 Florida State University Substituted taxanes as antitumour agents
WO1993018018A1 (en) * 1992-03-13 1993-09-16 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
US5367086A (en) * 1992-03-13 1994-11-22 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol
WO1994007880A1 (fr) * 1992-10-05 1994-04-14 Rhone-Poulenc Rorer S.A. Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent
WO1995004154A1 (en) * 1993-07-27 1995-02-09 Nippon Steel Corporation Process for producing taxol and its analogues using microorganisms
WO1997032578A1 (en) * 1996-03-04 1997-09-12 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
WO1997044063A2 (en) * 1996-05-22 1997-11-27 Neuromedica, Inc. Dha-pharmaceutical agent conjugates
WO1997044026A1 (en) * 1996-05-22 1997-11-27 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
WO1998002426A1 (en) * 1996-07-15 1998-01-22 Kabushiki Kaisha Yakult Honsha Taxane derivatives and drugs containing the same
WO1999014209A1 (en) * 1997-09-17 1999-03-25 Kabushiki Kaisha Yakult Honsha New taxane derivatives
WO1999032473A1 (en) * 1997-12-19 1999-07-01 Kabushiki Kaisha Yakult Honsha Taxane derivatives
WO2000053592A1 (en) * 1999-03-05 2000-09-14 Asahi Kasei Kabushiki Kaisha Osteogenesis promoters
WO2001057032A1 (en) * 2000-02-02 2001-08-09 Florida State University Research Foundation, Inc. C10 ester substituted taxanes as antitumor agents
JP2003521545A (ja) * 2000-02-02 2003-07-15 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 改良された溶解性を有するタキサン製剤
WO2001068089A1 (en) * 2000-03-17 2001-09-20 Indena S.P.A. Condensation derivatives of thiocolchicine and baccatin as antitumor agents

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007522236A (ja) * 2004-02-13 2007-08-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロペンチルエステル置換タキサン
JP4879757B2 (ja) * 2004-02-13 2012-02-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロペンチルエステル置換タキサン

Also Published As

Publication number Publication date
CA2354471A1 (en) 2003-01-31
EP1285920A1 (en) 2003-02-26

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