JP2002539265A - 抗腫瘍活性を有する薬剤を製造するための安定化オリゴヌクレオチドの使用 - Google Patents
抗腫瘍活性を有する薬剤を製造するための安定化オリゴヌクレオチドの使用Info
- Publication number
- JP2002539265A JP2002539265A JP2000606246A JP2000606246A JP2002539265A JP 2002539265 A JP2002539265 A JP 2002539265A JP 2000606246 A JP2000606246 A JP 2000606246A JP 2000606246 A JP2000606246 A JP 2000606246A JP 2002539265 A JP2002539265 A JP 2002539265A
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- tumor
- stabilized
- group
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9903433A FR2790955B1 (fr) | 1999-03-19 | 1999-03-19 | Utilisation d'oligonucleotides stabilises comme principe actif antitumoral |
| FR99/03433 | 1999-03-19 | ||
| PCT/FR2000/000676 WO2000056342A2 (fr) | 1999-03-19 | 2000-03-17 | Utilisation d'oligonucleotides stabilises pour la preparation d'un medicament a action antitumorale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002539265A true JP2002539265A (ja) | 2002-11-19 |
| JP2002539265A5 JP2002539265A5 (enExample) | 2007-05-17 |
Family
ID=9543401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000606246A Pending JP2002539265A (ja) | 1999-03-19 | 2000-03-17 | 抗腫瘍活性を有する薬剤を製造するための安定化オリゴヌクレオチドの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7700569B1 (enExample) |
| EP (1) | EP1162982B9 (enExample) |
| JP (1) | JP2002539265A (enExample) |
| AT (1) | ATE288759T1 (enExample) |
| AU (1) | AU3300600A (enExample) |
| CA (1) | CA2371990A1 (enExample) |
| DE (1) | DE60018050T2 (enExample) |
| DK (1) | DK1162982T3 (enExample) |
| ES (1) | ES2235839T3 (enExample) |
| FR (1) | FR2790955B1 (enExample) |
| PT (1) | PT1162982E (enExample) |
| WO (1) | WO2000056342A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2711670B1 (fr) * | 1993-10-22 | 1996-01-12 | Pasteur Institut | Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite. |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| SI1077722T1 (sl) | 1998-05-22 | 2007-02-28 | Ottawa Health Research Inst | Metode in produkti za induciranje sluznicne imunosti |
| US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| AU783344B2 (en) | 1999-02-17 | 2005-10-20 | Csl Limited | Immunogenic complexes and methods relating thereto |
| FR2790955B1 (fr) * | 1999-03-19 | 2003-01-17 | Assist Publ Hopitaux De Paris | Utilisation d'oligonucleotides stabilises comme principe actif antitumoral |
| IL160157A0 (en) | 2001-08-17 | 2004-07-25 | Coley Pharm Group Inc | Combination motif immune stimulation oligonucleotides with improved activity |
| US7605138B2 (en) | 2002-07-03 | 2009-10-20 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7576066B2 (en) | 2002-07-03 | 2009-08-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7807803B2 (en) | 2002-07-03 | 2010-10-05 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US20040053880A1 (en) | 2002-07-03 | 2004-03-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7569553B2 (en) * | 2002-07-03 | 2009-08-04 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| ZA200503511B (en) | 2002-10-29 | 2006-10-25 | Coley Pharmaceutical Group Ltd | Use of CPG oligonucleotides in the treatment of hepatitis C virus infection |
| US10100316B2 (en) * | 2002-11-21 | 2018-10-16 | Archemix Llc | Aptamers comprising CPG motifs |
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- 1999-03-19 FR FR9903433A patent/FR2790955B1/fr not_active Expired - Fee Related
-
2000
- 2000-03-17 DK DK00910993T patent/DK1162982T3/da active
- 2000-03-17 PT PT00910993T patent/PT1162982E/pt unknown
- 2000-03-17 ES ES00910993T patent/ES2235839T3/es not_active Expired - Lifetime
- 2000-03-17 JP JP2000606246A patent/JP2002539265A/ja active Pending
- 2000-03-17 CA CA002371990A patent/CA2371990A1/fr not_active Abandoned
- 2000-03-17 DE DE60018050T patent/DE60018050T2/de not_active Expired - Lifetime
- 2000-03-17 WO PCT/FR2000/000676 patent/WO2000056342A2/fr not_active Ceased
- 2000-03-17 EP EP00910993A patent/EP1162982B9/fr not_active Expired - Lifetime
- 2000-03-17 US US09/937,057 patent/US7700569B1/en not_active Expired - Fee Related
- 2000-03-17 AU AU33006/00A patent/AU3300600A/en not_active Abandoned
- 2000-03-17 AT AT00910993T patent/ATE288759T1/de active
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2001
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| JPH04352724A (ja) * | 1990-07-27 | 1992-12-07 | Mitsui Toatsu Chem Inc | 免疫調節型治療剤 |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1162982B9 (fr) | 2005-07-06 |
| ATE288759T1 (de) | 2005-02-15 |
| FR2790955A1 (fr) | 2000-09-22 |
| EP1162982A2 (fr) | 2001-12-19 |
| DK1162982T3 (da) | 2005-06-13 |
| WO2000056342A2 (fr) | 2000-09-28 |
| EP1162982B1 (fr) | 2005-02-09 |
| PT1162982E (pt) | 2005-05-31 |
| AU3300600A (en) | 2000-10-09 |
| CA2371990A1 (fr) | 2000-09-28 |
| US20020192184A1 (en) | 2002-12-19 |
| ES2235839T3 (es) | 2005-07-16 |
| DE60018050D1 (de) | 2005-03-17 |
| WO2000056342A3 (fr) | 2001-07-26 |
| US7700569B1 (en) | 2010-04-20 |
| DE60018050T2 (de) | 2006-02-23 |
| US7108844B2 (en) | 2006-09-19 |
| FR2790955B1 (fr) | 2003-01-17 |
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