JP2002536077A - 高度に鉱化されている骨形成性スポンジ組成物およびそれらの使用 - Google Patents

高度に鉱化されている骨形成性スポンジ組成物およびそれらの使用

Info

Publication number
JP2002536077A
JP2002536077A JP2000596990A JP2000596990A JP2002536077A JP 2002536077 A JP2002536077 A JP 2002536077A JP 2000596990 A JP2000596990 A JP 2000596990A JP 2000596990 A JP2000596990 A JP 2000596990A JP 2002536077 A JP2002536077 A JP 2002536077A
Authority
JP
Japan
Prior art keywords
osteogenic
sponge
bone
mineral material
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000596990A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002536077A5 (enExample
Inventor
マッケイ，ウィリアム・エフ
Original Assignee
エスディージーアイ・ホールディングス・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エスディージーアイ・ホールディングス・インコーポレーテッド filed Critical エスディージーアイ・ホールディングス・インコーポレーテッド
Publication of JP2002536077A publication Critical patent/JP2002536077A/ja
Publication of JP2002536077A5 publication Critical patent/JP2002536077A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Composite Materials (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2000596990A 1999-02-04 2000-02-04 高度に鉱化されている骨形成性スポンジ組成物およびそれらの使用 Pending JP2002536077A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11861599P 1999-02-04 1999-02-04
US60/118,615 1999-02-04
PCT/US2000/003043 WO2000045871A1 (en) 1999-02-04 2000-02-04 Highly-mineralized osteogenic sponge compositions, and uses thereof

Publications (2)

Publication Number Publication Date
JP2002536077A true JP2002536077A (ja) 2002-10-29
JP2002536077A5 JP2002536077A5 (enExample) 2007-03-22

Family

ID=22379695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000596990A Pending JP2002536077A (ja) 1999-02-04 2000-02-04 高度に鉱化されている骨形成性スポンジ組成物およびそれらの使用

Country Status (9)

Country Link
US (3) US7563455B2 (enExample)
EP (1) EP1150726B1 (enExample)
JP (1) JP2002536077A (enExample)
AT (1) ATE253385T1 (enExample)
AU (1) AU772682B2 (enExample)
CA (1) CA2362049A1 (enExample)
DE (1) DE60006356T2 (enExample)
ES (1) ES2209820T3 (enExample)
WO (1) WO2000045871A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006527009A (ja) * 2002-06-13 2006-11-30 ケンジー ナッシュ コーポレイション 生体組織における欠損を治療するための装置および方法
JP2008513100A (ja) * 2004-09-14 2008-05-01 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 多孔度生体材料−充填剤複合体およびその製法

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
DE60020526T2 (de) * 1999-02-04 2006-05-11 SDGI Holdings, Inc., Wilmington Osteogene pastenzusammensetzungen und ihre verwendung
CA2362049A1 (en) * 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Highly-mineralized osteogenic sponge compositions, and uses thereof
US7435260B2 (en) * 1999-08-13 2008-10-14 Ferree Bret A Use of morphogenetic proteins to treat human disc disease
ES2384405T3 (es) * 2000-10-24 2012-07-04 Warsaw Orthopedic, Inc. Dispositivos para fusionar vértebras
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
JP2003169845A (ja) * 2001-12-07 2003-06-17 Japan Science & Technology Corp スポンジ状多孔質アパタイト・コラーゲン複合体、スポンジ状超多孔質アパタイト・コラーゲン複合体及びそれらの製造方法
TW200400062A (en) 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
CN100522241C (zh) 2002-09-10 2009-08-05 Scil技术股份有限公司 在低氧气浓度下用骨诱导蛋白包被的金属植入物
US20060034803A1 (en) * 2002-11-07 2006-02-16 Masanori Nakasu Therapeutic device for osteogenesis
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US20070010892A1 (en) * 2003-08-27 2007-01-11 Makoto Ogiso Structural body constituted of biocompatible material impregnated with fine bone dust and process for producing the same
US7666230B2 (en) 2003-12-08 2010-02-23 Depuy Products, Inc. Implant device for cartilage regeneration in load bearing articulation regions
US7189263B2 (en) * 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US20050192675A1 (en) * 2004-03-01 2005-09-01 Robinson Dane Q. Device for use in stimulating bone growth
US9220595B2 (en) 2004-06-23 2015-12-29 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof
US7722895B1 (en) * 2004-09-20 2010-05-25 Warsaw Orthopedic, Inc. Osteogenic implants with combined implant materials, and materials and methods for same
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US7799754B2 (en) 2004-10-14 2010-09-21 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
US20060083769A1 (en) * 2004-10-14 2006-04-20 Mukesh Kumar Method and apparatus for preparing bone
US7670384B2 (en) * 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone
DE102005016443A1 (de) * 2004-11-23 2006-05-24 Ossacur Ag Bioresorbierbares und mineralisiertes Material zur Füllung von Knochendefekten
US20090155332A1 (en) * 2005-02-25 2009-06-18 Eugene Sherry Replacement bone tissue
EP1868539A2 (en) 2005-04-15 2007-12-26 Musculoskeletal Transplant Foundation Vertebral disc repair
US7857853B2 (en) * 2005-04-29 2010-12-28 Sdgi Holdings, Inc Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture
US8506646B2 (en) * 2005-04-29 2013-08-13 Warsaw Orthopedic, Inc. Multi-purpose medical implant devices
US8092548B2 (en) * 2005-06-22 2012-01-10 Warsaw Orthopedic, Inc. Osteograft treatment to promote osteoinduction and osteograft incorporation
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070077267A1 (en) * 2005-10-03 2007-04-05 Sdgi Holdings, Inc. Bioactive composite implants
US9005646B2 (en) 2005-10-12 2015-04-14 Lifenet Health Compositions for repair of defects in tissues, and methods of making the same
US9132208B2 (en) * 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
EP2431060B1 (en) 2005-11-17 2020-04-08 BioMimetic Therapeutics, LLC Maxillofacial bone augmentation using RHPDGF-BB and a biocompatible matrix
US7824703B2 (en) 2006-02-01 2010-11-02 Warsaw Orthopedics, Inc. Medical implants with reservoir(s), and materials preparable from same
US7939092B2 (en) * 2006-02-01 2011-05-10 Warsaw Orthopedic, Inc. Cohesive osteogenic putty and materials therefor
US7833270B2 (en) * 2006-05-05 2010-11-16 Warsaw Orthopedic, Inc Implant depots to deliver growth factors to treat osteoporotic bone
ES2664229T3 (es) 2006-06-30 2018-04-18 Biomimetic Therapeutics, Llc Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US7959683B2 (en) 2006-07-25 2011-06-14 Musculoskeletal Transplant Foundation Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation
US8524265B2 (en) * 2006-08-17 2013-09-03 Warsaw Orthopedic, Inc. Medical implant sheets useful for tissue regeneration
JP5552315B2 (ja) 2006-11-03 2014-07-16 バイオミメティック セラピューティクス， エルエルシー アースロデティック術のための組成物および方法
US20080147197A1 (en) * 2006-12-14 2008-06-19 Mckay William F Biodegradable osteogenic porous biomedical implant with impermeable membrane
US8048857B2 (en) * 2006-12-19 2011-11-01 Warsaw Orthopedic, Inc. Flowable carrier compositions and methods of use
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
CA2720269A1 (en) * 2007-04-18 2008-10-30 Mcgill University Composition for enhancing bone formation
EP2014256A1 (en) 2007-07-12 2009-01-14 Straumann Holding AG Composite bone repair material
WO2009038783A1 (en) 2007-09-19 2009-03-26 Surmodics, Inc. Biocompatible foams, systems, and methods
US20090110637A1 (en) * 2007-10-26 2009-04-30 Warsaw Orthopedic, Inc. LMP and Regulation of Tissue Growth
US9056150B2 (en) 2007-12-04 2015-06-16 Warsaw Orthopedic, Inc. Compositions for treating bone defects
WO2009100454A1 (en) * 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
US8840913B2 (en) 2008-03-27 2014-09-23 Warsaw Orthopedic, Inc. Malleable multi-component implants and materials therefor
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
US9492375B2 (en) * 2008-07-23 2016-11-15 Warsaw Orthopedic, Inc. Foam carrier for bone grafting
US8039433B2 (en) * 2008-08-19 2011-10-18 Warsaw Orthopedic, Inc. Osteogenic compositions containing a coloring agent
NZ602861A (en) 2008-09-09 2014-03-28 Biomimetic Therapeutics Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US9192695B2 (en) 2008-11-20 2015-11-24 Allosource Allografts combined with tissue derived stem cells for bone healing
JP2012519556A (ja) * 2009-03-05 2012-08-30 バイオミメティック セラピューティクス， インコーポレイテッド 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法
US20110060419A1 (en) * 2009-03-27 2011-03-10 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
US20110117171A1 (en) * 2009-11-18 2011-05-19 Affinergy, Inc. Implantable bone graft materials
US8758791B2 (en) 2010-01-26 2014-06-24 Warsaw Orthopedic, Inc. Highly compression resistant matrix with porous skeleton
US8475824B2 (en) 2010-01-26 2013-07-02 Warsaw Orthopedic, Inc. Resorbable matrix having elongated particles
CA2790403C (en) 2010-02-22 2019-08-27 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
US8501690B2 (en) 2010-04-30 2013-08-06 John G. Stark Use of selective estrogen receptor modulator for joint fusion and other repair or healing of connective tissue
US9265857B2 (en) 2010-05-11 2016-02-23 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods
PH12013500294A1 (en) 2010-08-20 2017-08-23 Wyeth Llc Designer osteogenic proteins
WO2012068135A1 (en) 2010-11-15 2012-05-24 Zimmer Orthobiologics, Inc. Bone void fillers
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
US9358122B2 (en) 2011-01-07 2016-06-07 K2M, Inc. Interbody spacer
US9717779B2 (en) 2011-01-31 2017-08-01 Warsaw Orthopedic, Inc. Implantable matrix having optimum ligand concentrations
WO2012161788A1 (en) * 2011-02-25 2012-11-29 Synthes Usa, Llc Osteogenic promoting implants and methods of inducing bone growth
WO2012158527A2 (en) 2011-05-13 2012-11-22 Howmedica Osteonics Organophosphorous & multivalent metal compound compositions & methods
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
WO2012177759A1 (en) 2011-06-20 2012-12-27 Rdc Holdings, Llc System and method for repairing joints
US8998925B2 (en) 2011-06-20 2015-04-07 Rdc Holdings, Llc Fixation system for orthopedic devices
WO2013075091A1 (en) 2011-11-17 2013-05-23 Allosource Multi-piece machine graft systems and methods
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
US9642933B2 (en) 2012-01-30 2017-05-09 Board Of Regents, The University Of Texas System Compositions comprising bioadhesives and methods of making the same
WO2013123509A1 (en) * 2012-02-17 2013-08-22 Bacterin International, Inc. Adjustable bioactive agent dispersion within a polymeric coating
US8697107B2 (en) 2012-04-27 2014-04-15 Warsaw Orthopedic, Inc. Flowable implant with crosslinkable surface membrane
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
US9585764B2 (en) * 2012-07-26 2017-03-07 Warsaw Orthopedic, Inc. Bone implant device
JP6286447B2 (ja) 2013-01-04 2018-02-28 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム シトラートを含む組成物およびその適用
US9186253B2 (en) 2013-02-22 2015-11-17 Allosource Cartilage mosaic compositions and methods
EP2964154A4 (en) 2013-03-07 2016-08-17 Allosource BONE ALLOTRANSPLATE SYSTEMS AND METHODS WITH CONSISTENT CALCIUM CONTENT
US20140271471A1 (en) * 2013-03-14 2014-09-18 Genzyme Corporation Thermo-sensitive bone growth compositions
WO2014150784A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
WO2014151939A1 (en) 2013-03-15 2014-09-25 Allosource Perforated osteochondral allograft compositions
US9539286B2 (en) 2013-10-18 2017-01-10 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9486483B2 (en) 2013-10-18 2016-11-08 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9579421B2 (en) 2014-02-07 2017-02-28 Globus Medical Inc. Bone grafts and methods of making and using bone grafts
US9463264B2 (en) 2014-02-11 2016-10-11 Globus Medical, Inc. Bone grafts and methods of making and using bone grafts
US9730796B2 (en) 2014-05-16 2017-08-15 Allosource Composite bone constructs and methods
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
KR20170100634A (ko) 2014-12-29 2017-09-04 바이오벤터스 엘엘씨 골 복구에서의 골유도 분자의 전달 향상을 위한 시스템 및 방법
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US11426489B2 (en) 2015-06-10 2022-08-30 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US10016529B2 (en) 2015-06-10 2018-07-10 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
WO2017100339A1 (en) * 2015-12-07 2017-06-15 Nuvasive, Inc. Immunomodulation with implantation of cellular allograft bone into a non-bony site
US20170319750A1 (en) * 2016-05-09 2017-11-09 Bioventus, Llc Composite matrices designed for enhanced bone repair
WO2018189384A1 (en) 2017-04-13 2018-10-18 Septodont Ou Septodont Sas Ou Specialites Septodont Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate
EP3388092A1 (en) 2017-04-13 2018-10-17 Septodont ou Septodont SAS ou Specialites Septodont Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate
WO2019006328A1 (en) 2017-06-30 2019-01-03 Allosource CELL BONE GRAFTS, AND METHODS OF MAKING AND USING
US11896736B2 (en) 2020-07-13 2024-02-13 Globus Medical, Inc Biomaterial implants and methods of making the same
US11883302B2 (en) 2021-11-22 2024-01-30 Warsaw Orthopedic, Inc. Spinal implant having a compressible insert

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030583B1 (de) 1979-12-18 1984-06-13 Oscobal Ag Knochenersatzmaterial und Verfahren zur Herstellung eines Knochenersatzmaterials
US4394370A (en) 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
US4888366A (en) * 1984-10-24 1989-12-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5001169A (en) * 1984-10-24 1991-03-19 Collagen Corporation Inductive collagen-based bone repair preparations
US5273964A (en) 1985-03-20 1993-12-28 Lemons J E Inorganic and organic composition for treatment of bone lesions
US5246457A (en) 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4992226A (en) 1985-03-28 1991-02-12 Collagen Corporation Method of making molds with xenogeneic collagen/mineral preparations for bone repair
US4776890A (en) 1985-12-18 1988-10-11 Collagen Corporation Preparation of collagen hydroxyapatite matrix for bone repair
US4780450A (en) 1985-12-20 1988-10-25 The University Of Maryland At Baltimore Physically stable composition and method of use thereof for osseous repair
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4865602A (en) 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
US4861733A (en) * 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
WO1989004646A1 (en) * 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
US5573771A (en) * 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
US5106626A (en) * 1988-10-11 1992-04-21 International Genetic Engineering, Inc. Osteogenic factors
US5231169A (en) * 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US5626861A (en) * 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
US5817327A (en) * 1994-07-27 1998-10-06 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
CN1134810A (zh) * 1995-02-17 1996-11-06 索发默达纳集团股份有限公司 改进的体内脊骨融合植入件
CN1192700A (zh) * 1995-06-06 1998-09-09 基因科学再生实验室有限公司 改性成骨材料
CA2172917A1 (en) 1995-06-07 1996-12-08 Hugh R. Mcmullin Moldable collagen compositions for hard tissue repair and augmentation
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
EP0883410B1 (en) * 1996-02-29 2004-08-18 Bioactive Bone Substitute OY, AB An osteogenic device and a method for preparing the device
DE69739540D1 (de) * 1996-04-19 2009-10-01 Osiris Therapeutics Inc Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen
US5741261A (en) * 1996-06-25 1998-04-21 Sdgi Holdings, Inc. Minimally invasive spinal surgical methods and instruments
AU734950B2 (en) * 1996-10-24 2001-06-28 Warsaw Orthopedic, Inc. Ceramic fusion implants and compositions containing osteoinductive factors
US5972368A (en) * 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
CA2362049A1 (en) * 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Highly-mineralized osteogenic sponge compositions, and uses thereof

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
JPN6008044273, Ｊｏｕｒｎａｌ ｏｆ Ｂｏｎｅ ａｎｄ Ｍｉｎｅｒａｌ Ｒｅｓｅａｒｃｈ, 1998, Ｖｏｌ．１３，Ｎｏ．９, ｐ１４８３−１４９０ *
JPN6010056712, Ｊｏｕｒｎａｌ ｏｆ Ｓｐｉｎａｌ Ｄｉｓｏｒｄｅｒｓ, 1997, Ｖｏｌ．１０，Ｎｏ．６, ｐ４６７−４７２ *
JPN6010056713, Ｓｐｉｎｅ, 1995, Ｖｏｌ．２０，Ｎｏ．１２, ｐ１３２６−１３３７ *
JPN6010056715, Ｓｐｉｎｅ, 1996, Ｖｏｌ．２１，Ｎｏ．２２, ｐ２６８９−２６９７ *
JPN6010056717, Ｊｏｕｒｎａｌ ｏｆ Ｓｐｉｎａｌ Ｄｉｓｏｒｄｅｒｓ, 1998, Ｖｏｌ．１１，Ｎｏ．２, ｐ９５−１０１ *
JPN6010056718, Ｓｐｉｎｅ, 1995, Ｖｏｌ．２０，Ｎｏ．２０, ｐ２２０３−２２１０ *
JPN6010056719, 臨床整形外科, 1986, Ｖｏｌ．２１，Ｎｏ．１１, ｐ１２５９−１２６５ *
JPN6010056721, 日本歯周病学会会誌, 1990, Ｖｏｌ．３２，Ｎｏ．３, ｐ８００−８１０ *
JPN6010056722, 日本歯周病学会会誌, 1995, Ｖｏｌ．３７，Ｎｏ．３, ｐ４４３−４５６ *
JPN7010003504, 南アフリカ国特許公報第９８６７６３号明細書, 19990201 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006527009A (ja) * 2002-06-13 2006-11-30 ケンジー ナッシュ コーポレイション 生体組織における欠損を治療するための装置および方法
JP2008513100A (ja) * 2004-09-14 2008-05-01 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 多孔度生体材料−充填剤複合体およびその製法

Also Published As

Publication number Publication date
ATE253385T1 (de) 2003-11-15
DE60006356D1 (de) 2003-12-11
US8399010B2 (en) 2013-03-19
CA2362049A1 (en) 2000-08-10
AU2756800A (en) 2000-08-25
DE60006356T2 (de) 2004-09-09
WO2000045871A1 (en) 2000-08-10
US20120141557A1 (en) 2012-06-07
EP1150726B1 (en) 2003-11-05
US7563455B2 (en) 2009-07-21
US8147862B2 (en) 2012-04-03
AU772682B2 (en) 2004-05-06
EP1150726A1 (en) 2001-11-07
ES2209820T3 (es) 2004-07-01
US20020082694A1 (en) 2002-06-27
US20090196904A1 (en) 2009-08-06

Similar Documents

Publication Publication Date Title
US8399010B2 (en) Highly-mineralized osteogenic sponge compositions and uses thereof
AU770196B2 (en) Osteogenic paste compositions and uses thereof
US9931435B2 (en) Medical implants with reservoir(s), and materials preparable from same
Levine et al. Bone morphogenetic protein promotes vascularization and osteoinduction in preformed hydroxyapatite in the rabbit
US8734835B2 (en) Cohesive osteogenic putty and materials therefor
JP4703926B2 (ja) 骨形成蛋白をデリバリーするためのヒアルロン酸の処方
US7771741B2 (en) Demineralized bone matrix devices
Breitbart et al. Tricalcium phosphate and osteogenin: a bioactive onlay bone graft substitute
EP0616814A1 (en) Compositions for controlled release of biologically active TGF - beta
JP2004262758A (ja) 多孔性β−リン酸三カルシウム顆粒および同一のものを生成する方法
WO2012068135A1 (en) Bone void fillers
WO2010050935A1 (en) Devices containing demineralized bone matrix particles
EP1454640A2 (en) Formulations of hyaluronic acid for delivery of osteogenic proteins

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20061011

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070202

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101027

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110127

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110203

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110224

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110303

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110323

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110330

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110427

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20110915

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20111031