ATE253385T1 - Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung - Google Patents
Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendungInfo
- Publication number
- ATE253385T1 ATE253385T1 AT00905989T AT00905989T ATE253385T1 AT E253385 T1 ATE253385 T1 AT E253385T1 AT 00905989 T AT00905989 T AT 00905989T AT 00905989 T AT00905989 T AT 00905989T AT E253385 T1 ATE253385 T1 AT E253385T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- osteogenic
- highly mineralized
- bone
- osteogenic sponge
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000002188 osteogenic effect Effects 0.000 title abstract 3
- 210000000988 bone and bone Anatomy 0.000 abstract 2
- 230000002138 osteoinductive effect Effects 0.000 abstract 2
- 102000007350 Bone Morphogenetic Proteins Human genes 0.000 abstract 1
- 108010007726 Bone Morphogenetic Proteins Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940112869 bone morphogenetic protein Drugs 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Materials Engineering (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Composite Materials (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11861599P | 1999-02-04 | 1999-02-04 | |
| PCT/US2000/003043 WO2000045871A1 (en) | 1999-02-04 | 2000-02-04 | Highly-mineralized osteogenic sponge compositions, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE253385T1 true ATE253385T1 (de) | 2003-11-15 |
Family
ID=22379695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00905989T ATE253385T1 (de) | 1999-02-04 | 2000-02-04 | Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7563455B2 (enExample) |
| EP (1) | EP1150726B1 (enExample) |
| JP (1) | JP2002536077A (enExample) |
| AT (1) | ATE253385T1 (enExample) |
| AU (1) | AU772682B2 (enExample) |
| CA (1) | CA2362049A1 (enExample) |
| DE (1) | DE60006356T2 (enExample) |
| ES (1) | ES2209820T3 (enExample) |
| WO (1) | WO2000045871A1 (enExample) |
Families Citing this family (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040081704A1 (en) | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
| EP1150725B1 (en) * | 1999-02-04 | 2005-06-01 | SDGI Holdings, Inc. | Osteogenic paste compositions and uses thereof |
| DE60006356T2 (de) * | 1999-02-04 | 2004-09-09 | SDGI Holding, Inc., Wilmington | Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung |
| US7435260B2 (en) * | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
| ES2319506T3 (es) * | 2000-10-24 | 2009-05-08 | Warsaw Orthopedic, Inc. | Metodos y dispositivos de fusion vertebral. |
| US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
| US6949251B2 (en) | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
| DK1448246T4 (en) | 2001-11-19 | 2015-12-21 | Scil Technology Gmbh | Homogeneously coated device with osteoinductive and osteoconductive properties |
| JP2003169845A (ja) * | 2001-12-07 | 2003-06-17 | Japan Science & Technology Corp | スポンジ状多孔質アパタイト・コラーゲン複合体、スポンジ状超多孔質アパタイト・コラーゲン複合体及びそれらの製造方法 |
| TW200400062A (en) | 2002-04-03 | 2004-01-01 | Mathys Medizinaltechnik Ag | Kneadable, pliable bone replacement material |
| US7166133B2 (en) * | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
| PL207552B1 (pl) | 2002-09-10 | 2010-12-31 | Scil Technology Gmbh | Sposób wytwarzania urządzenia, urządzenie, kompozycja farmaceutyczna, zastosowanie urządzenia i zestaw |
| WO2004041319A1 (ja) * | 2002-11-07 | 2004-05-21 | Pentax Corporation | 骨形成治療デバイス |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US8734421B2 (en) | 2003-06-30 | 2014-05-27 | Johnson & Johnson Consumer Companies, Inc. | Methods of treating pores on the skin with electricity |
| AU2003261747A1 (en) * | 2003-08-27 | 2005-03-29 | Makoto Ogiso | Structural body constituted of biocompatible material impregnated with fine bone dust and process for producing the same |
| US7666230B2 (en) | 2003-12-08 | 2010-02-23 | Depuy Products, Inc. | Implant device for cartilage regeneration in load bearing articulation regions |
| US7189263B2 (en) * | 2004-02-03 | 2007-03-13 | Vita Special Purpose Corporation | Biocompatible bone graft material |
| US20050192675A1 (en) * | 2004-03-01 | 2005-09-01 | Robinson Dane Q. | Device for use in stimulating bone growth |
| US9220595B2 (en) | 2004-06-23 | 2015-12-29 | Orthovita, Inc. | Shapeable bone graft substitute and instruments for delivery thereof |
| US20090012625A1 (en) * | 2004-09-14 | 2009-01-08 | Ying Jackie Y | Porous biomaterial-filler composite and method for making the same |
| US7722895B1 (en) | 2004-09-20 | 2010-05-25 | Warsaw Orthopedic, Inc. | Osteogenic implants with combined implant materials, and materials and methods for same |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US20060083769A1 (en) * | 2004-10-14 | 2006-04-20 | Mukesh Kumar | Method and apparatus for preparing bone |
| US7670384B2 (en) * | 2004-10-14 | 2010-03-02 | Biomet Manufacturing Corp. | Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone |
| US7473678B2 (en) * | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| DE102005016443A1 (de) * | 2004-11-23 | 2006-05-24 | Ossacur Ag | Bioresorbierbares und mineralisiertes Material zur Füllung von Knochendefekten |
| WO2006089359A1 (en) * | 2005-02-25 | 2006-08-31 | Eugene Sherry | Replacement bone tissue |
| CA2604622A1 (en) | 2005-04-15 | 2006-10-26 | Musculoskeletal Transplant Foundation | Vertebral disc repair |
| US7857853B2 (en) * | 2005-04-29 | 2010-12-28 | Sdgi Holdings, Inc | Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture |
| US8506646B2 (en) * | 2005-04-29 | 2013-08-13 | Warsaw Orthopedic, Inc. | Multi-purpose medical implant devices |
| US8092548B2 (en) * | 2005-06-22 | 2012-01-10 | Warsaw Orthopedic, Inc. | Osteograft treatment to promote osteoinduction and osteograft incorporation |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| WO2007035778A2 (en) | 2005-09-19 | 2007-03-29 | Histogenics Corporation | Cell-support matrix and a method for preparation thereof |
| US20070077267A1 (en) * | 2005-10-03 | 2007-04-05 | Sdgi Holdings, Inc. | Bioactive composite implants |
| US9132208B2 (en) * | 2008-08-07 | 2015-09-15 | Lifenet Health | Composition for a tissue repair implant and methods of making the same |
| US9005646B2 (en) | 2005-10-12 | 2015-04-14 | Lifenet Health | Compositions for repair of defects in tissues, and methods of making the same |
| BRPI0618794A2 (pt) | 2005-11-17 | 2011-09-13 | Biomimetic Therapeutics Inc | uso de uma matriz biocompatìvel, kit e composição para aumento ósseo, especialmente para aumento do osso maxilofacial |
| US7939092B2 (en) * | 2006-02-01 | 2011-05-10 | Warsaw Orthopedic, Inc. | Cohesive osteogenic putty and materials therefor |
| US7824703B2 (en) | 2006-02-01 | 2010-11-02 | Warsaw Orthopedics, Inc. | Medical implants with reservoir(s), and materials preparable from same |
| EP2311505B1 (en) * | 2006-02-09 | 2013-11-06 | BioMimetic Therapeutics, LLC | Compositions and methods for treating bone |
| US7833270B2 (en) * | 2006-05-05 | 2010-11-16 | Warsaw Orthopedic, Inc | Implant depots to deliver growth factors to treat osteoporotic bone |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
| US7959683B2 (en) | 2006-07-25 | 2011-06-14 | Musculoskeletal Transplant Foundation | Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation |
| US8524265B2 (en) * | 2006-08-17 | 2013-09-03 | Warsaw Orthopedic, Inc. | Medical implant sheets useful for tissue regeneration |
| WO2008073628A2 (en) | 2006-11-03 | 2008-06-19 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
| US20080147197A1 (en) * | 2006-12-14 | 2008-06-19 | Mckay William F | Biodegradable osteogenic porous biomedical implant with impermeable membrane |
| US8048857B2 (en) * | 2006-12-19 | 2011-11-01 | Warsaw Orthopedic, Inc. | Flowable carrier compositions and methods of use |
| US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
| US20080195476A1 (en) * | 2007-02-09 | 2008-08-14 | Marchese Michael A | Abandonment remarketing system |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| EP2148708A4 (en) * | 2007-04-18 | 2012-12-05 | Univ Mcgill | COMPOSITION FOR PROMOTING BONE FORMATION |
| EP2014256A1 (en) | 2007-07-12 | 2009-01-14 | Straumann Holding AG | Composite bone repair material |
| WO2009038783A1 (en) | 2007-09-19 | 2009-03-26 | Surmodics, Inc. | Biocompatible foams, systems, and methods |
| US20090110637A1 (en) * | 2007-10-26 | 2009-04-30 | Warsaw Orthopedic, Inc. | LMP and Regulation of Tissue Growth |
| US9056150B2 (en) | 2007-12-04 | 2015-06-16 | Warsaw Orthopedic, Inc. | Compositions for treating bone defects |
| ES2422259T3 (es) | 2008-02-07 | 2013-09-10 | Biomimetic Therapeutics Inc | Composiciones para la osteogénesis por distracción |
| CA2717725A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US8840913B2 (en) * | 2008-03-27 | 2014-09-23 | Warsaw Orthopedic, Inc. | Malleable multi-component implants and materials therefor |
| PL2288376T3 (pl) | 2008-04-18 | 2016-07-29 | Collplant Ltd | Sposoby generowania i wykorzystywania prokolagenu |
| US9492375B2 (en) | 2008-07-23 | 2016-11-15 | Warsaw Orthopedic, Inc. | Foam carrier for bone grafting |
| US8039433B2 (en) | 2008-08-19 | 2011-10-18 | Warsaw Orthopedic, Inc. | Osteogenic compositions containing a coloring agent |
| MX2011002555A (es) | 2008-09-09 | 2011-08-03 | Biomimetic Therapeutics Inc | Composiciones de factor de crecimiento derivadas de plaquetas y metodo para el tratamiento de lesiones de tendon y ligamentos. |
| US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス, インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
| US20110060419A1 (en) * | 2009-03-27 | 2011-03-10 | Jennifer Hagyoung Kang Choi | Medical devices with galvanic particulates |
| US20120089232A1 (en) | 2009-03-27 | 2012-04-12 | Jennifer Hagyoung Kang Choi | Medical devices with galvanic particulates |
| US20110117166A1 (en) * | 2009-11-18 | 2011-05-19 | Affinergy, Inc. | Implantable bone graft materials |
| US20140286911A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
| US8758791B2 (en) | 2010-01-26 | 2014-06-24 | Warsaw Orthopedic, Inc. | Highly compression resistant matrix with porous skeleton |
| US8475824B2 (en) | 2010-01-26 | 2013-07-02 | Warsaw Orthopedic, Inc. | Resorbable matrix having elongated particles |
| CN107080834A (zh) | 2010-02-22 | 2017-08-22 | 生物模拟治疗有限责任公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
| US8501690B2 (en) | 2010-04-30 | 2013-08-06 | John G. Stark | Use of selective estrogen receptor modulator for joint fusion and other repair or healing of connective tissue |
| US9265857B2 (en) | 2010-05-11 | 2016-02-23 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods |
| CA2807343C (en) | 2010-08-20 | 2018-05-22 | Wyeth Llc | Designer osteogenic proteins |
| CN103313733A (zh) | 2010-11-15 | 2013-09-18 | 捷迈整形外科生物材料有限公司 | 骨空隙填充剂 |
| US8551525B2 (en) | 2010-12-23 | 2013-10-08 | Biostructures, Llc | Bone graft materials and methods |
| US9358122B2 (en) | 2011-01-07 | 2016-06-07 | K2M, Inc. | Interbody spacer |
| US9717779B2 (en) | 2011-01-31 | 2017-08-01 | Warsaw Orthopedic, Inc. | Implantable matrix having optimum ligand concentrations |
| WO2012161788A1 (en) * | 2011-02-25 | 2012-11-29 | Synthes Usa, Llc | Osteogenic promoting implants and methods of inducing bone growth |
| US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
| EP2529764A1 (de) | 2011-05-31 | 2012-12-05 | Curasan AG | Biologisch degradierbares kompositmaterial |
| WO2012177759A1 (en) | 2011-06-20 | 2012-12-27 | Rdc Holdings, Llc | System and method for repairing joints |
| US8998925B2 (en) | 2011-06-20 | 2015-04-07 | Rdc Holdings, Llc | Fixation system for orthopedic devices |
| WO2013075091A1 (en) | 2011-11-17 | 2013-05-23 | Allosource | Multi-piece machine graft systems and methods |
| US9162011B2 (en) | 2011-12-19 | 2015-10-20 | Allosource | Flowable matrix compositions and methods |
| US9642933B2 (en) | 2012-01-30 | 2017-05-09 | Board Of Regents, The University Of Texas System | Compositions comprising bioadhesives and methods of making the same |
| US20150031772A1 (en) * | 2012-02-17 | 2015-01-29 | Bacterin International, Inc. | Adjustable bioactive agent dispersion within a polymeric coating |
| US8697107B2 (en) | 2012-04-27 | 2014-04-15 | Warsaw Orthopedic, Inc. | Flowable implant with crosslinkable surface membrane |
| US10207027B2 (en) | 2012-06-11 | 2019-02-19 | Globus Medical, Inc. | Bioactive bone graft substitutes |
| US9585764B2 (en) * | 2012-07-26 | 2017-03-07 | Warsaw Orthopedic, Inc. | Bone implant device |
| EP2941482B1 (en) | 2013-01-04 | 2020-11-25 | Board Of Regents, The University Of Texas System | Compositions comprising citrate and applications thereof |
| EP2958523B1 (en) | 2013-02-22 | 2020-04-22 | AlloSource | Cartilage mosaic compositions and methods |
| CA2897855A1 (en) | 2013-03-07 | 2014-09-12 | Allosource | Consistent calcium content bone allograft systems and methods |
| HK1220216A1 (zh) * | 2013-03-14 | 2017-04-28 | Genzyme Corporation | 温敏性骨生长组合物 |
| US9168140B2 (en) | 2013-03-15 | 2015-10-27 | Allosource | Perforated osteochondral allograft compositions |
| US9539286B2 (en) | 2013-10-18 | 2017-01-10 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9486483B2 (en) | 2013-10-18 | 2016-11-08 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9579421B2 (en) | 2014-02-07 | 2017-02-28 | Globus Medical Inc. | Bone grafts and methods of making and using bone grafts |
| US9463264B2 (en) | 2014-02-11 | 2016-10-11 | Globus Medical, Inc. | Bone grafts and methods of making and using bone grafts |
| WO2015175983A1 (en) | 2014-05-16 | 2015-11-19 | Allosource | Composite bone constructs and methods |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| EP3240563B1 (en) | 2014-12-29 | 2020-12-09 | Bioventus LLC | Systems and methods for improved delivery of osteoinductive molecules in bone repair |
| WO2016187413A1 (en) | 2015-05-21 | 2016-11-24 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| US11426489B2 (en) | 2015-06-10 | 2022-08-30 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US10016529B2 (en) | 2015-06-10 | 2018-07-10 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| WO2017100339A1 (en) * | 2015-12-07 | 2017-06-15 | Nuvasive, Inc. | Immunomodulation with implantation of cellular allograft bone into a non-bony site |
| US20170319750A1 (en) * | 2016-05-09 | 2017-11-09 | Bioventus, Llc | Composite matrices designed for enhanced bone repair |
| BR112019021533B1 (pt) | 2017-04-13 | 2023-02-14 | Septodont Ou Septodont Sas Ou Specialites Septodont | Material regenerativo de tecidos conjuntivos, tais como osso, dentina ou polpa, compreendendo silicato de cálcio |
| EP3388092A1 (en) | 2017-04-13 | 2018-10-17 | Septodont ou Septodont SAS ou Specialites Septodont | Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate |
| EP3645066A1 (en) | 2017-06-30 | 2020-05-06 | Allosource | Cellular bone grafts, and methods of manufacture and use |
| US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
| US11883302B2 (en) | 2021-11-22 | 2024-01-30 | Warsaw Orthopedic, Inc. | Spinal implant having a compressible insert |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2967060D1 (en) | 1979-12-18 | 1984-07-19 | Oscobal Ag | Bone replacement material and process for producing a bone replacement material |
| US4394370A (en) | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
| US4795804A (en) * | 1983-08-16 | 1989-01-03 | The Regents Of The University Of California | Bone morphogenetic agents |
| US5001169A (en) * | 1984-10-24 | 1991-03-19 | Collagen Corporation | Inductive collagen-based bone repair preparations |
| US4888366A (en) * | 1984-10-24 | 1989-12-19 | Collagen Corporation | Inductive collagen-based bone repair preparations |
| US5273964A (en) | 1985-03-20 | 1993-12-28 | Lemons J E | Inorganic and organic composition for treatment of bone lesions |
| US4992226A (en) | 1985-03-28 | 1991-02-12 | Collagen Corporation | Method of making molds with xenogeneic collagen/mineral preparations for bone repair |
| US5246457A (en) | 1985-03-28 | 1993-09-21 | Collagen Corporation | Xenogeneic collagen/mineral preparations in bone repair |
| US4776890A (en) | 1985-12-18 | 1988-10-11 | Collagen Corporation | Preparation of collagen hydroxyapatite matrix for bone repair |
| US4780450A (en) | 1985-12-20 | 1988-10-25 | The University Of Maryland At Baltimore | Physically stable composition and method of use thereof for osseous repair |
| US4743229A (en) | 1986-09-29 | 1988-05-10 | Collagen Corporation | Collagen/mineral mixing device and method |
| US4865602A (en) | 1986-11-06 | 1989-09-12 | Collagen Corporation | Gamma irradiation of collagen/mineral mixtures |
| US4861733A (en) * | 1987-02-13 | 1989-08-29 | Interpore International | Calcium phosphate bone substitute materials |
| CA1339083C (en) * | 1987-11-13 | 1997-07-29 | Steven R. Jefferies | Bone repair material and delayed drug delivery system |
| US5593409A (en) * | 1988-06-13 | 1997-01-14 | Sofamor Danek Group, Inc. | Interbody spinal fusion implants |
| US5573771A (en) * | 1988-08-19 | 1996-11-12 | Osteomedical Limited | Medicinal bone mineral products |
| US5106626A (en) * | 1988-10-11 | 1992-04-21 | International Genetic Engineering, Inc. | Osteogenic factors |
| US5231169A (en) * | 1990-10-17 | 1993-07-27 | Norian Corporation | Mineralized collagen |
| US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
| US5626861A (en) * | 1994-04-01 | 1997-05-06 | Massachusetts Institute Of Technology | Polymeric-hydroxyapatite bone composite |
| US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| AU6107496A (en) * | 1995-06-06 | 1996-12-24 | Gensci Regeneration Laboratories, Inc. | Modified osteogenic materials |
| CA2172917A1 (en) | 1995-06-07 | 1996-12-08 | Hugh R. Mcmullin | Moldable collagen compositions for hard tissue repair and augmentation |
| US5702449A (en) * | 1995-06-07 | 1997-12-30 | Danek Medical, Inc. | Reinforced porous spinal implants |
| US5776193A (en) | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
| AU4721696A (en) * | 1996-02-29 | 1997-09-16 | T. Sam Lindholm | An osteogenic device and a method for preparing the device |
| CA2251983C (en) * | 1996-04-19 | 2003-12-16 | Sudhakar Kadiyala | Regeneration and augmentation of bone using mesenchymal stem cells |
| US5741261A (en) * | 1996-06-25 | 1998-04-21 | Sdgi Holdings, Inc. | Minimally invasive spinal surgical methods and instruments |
| WO1998017330A1 (en) * | 1996-10-24 | 1998-04-30 | Sdgi Holdings, Inc. | Ceramic fusion implants and compositions containing osteoinductive factors |
| US5972368A (en) * | 1997-06-11 | 1999-10-26 | Sdgi Holdings, Inc. | Bone graft composites and spacers |
| DE60006356T2 (de) * | 1999-02-04 | 2004-09-09 | SDGI Holding, Inc., Wilmington | Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung |
-
2000
- 2000-02-04 DE DE60006356T patent/DE60006356T2/de not_active Expired - Fee Related
- 2000-02-04 CA CA002362049A patent/CA2362049A1/en not_active Abandoned
- 2000-02-04 AU AU27568/00A patent/AU772682B2/en not_active Ceased
- 2000-02-04 AT AT00905989T patent/ATE253385T1/de not_active IP Right Cessation
- 2000-02-04 ES ES00905989T patent/ES2209820T3/es not_active Expired - Lifetime
- 2000-02-04 EP EP00905989A patent/EP1150726B1/en not_active Expired - Lifetime
- 2000-02-04 JP JP2000596990A patent/JP2002536077A/ja active Pending
- 2000-02-04 WO PCT/US2000/003043 patent/WO2000045871A1/en not_active Ceased
-
2001
- 2001-08-06 US US09/923,116 patent/US7563455B2/en not_active Expired - Fee Related
-
2009
- 2009-01-16 US US12/355,569 patent/US8147862B2/en not_active Expired - Fee Related
-
2012
- 2012-02-09 US US13/369,929 patent/US8399010B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20120141557A1 (en) | 2012-06-07 |
| WO2000045871A1 (en) | 2000-08-10 |
| US8399010B2 (en) | 2013-03-19 |
| CA2362049A1 (en) | 2000-08-10 |
| JP2002536077A (ja) | 2002-10-29 |
| EP1150726B1 (en) | 2003-11-05 |
| EP1150726A1 (en) | 2001-11-07 |
| US20020082694A1 (en) | 2002-06-27 |
| US8147862B2 (en) | 2012-04-03 |
| DE60006356D1 (de) | 2003-12-11 |
| US7563455B2 (en) | 2009-07-21 |
| ES2209820T3 (es) | 2004-07-01 |
| DE60006356T2 (de) | 2004-09-09 |
| AU2756800A (en) | 2000-08-25 |
| AU772682B2 (en) | 2004-05-06 |
| US20090196904A1 (en) | 2009-08-06 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |