JP2002532094A5 - - Google Patents
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- Publication number
- JP2002532094A5 JP2002532094A5 JP2000588357A JP2000588357A JP2002532094A5 JP 2002532094 A5 JP2002532094 A5 JP 2002532094A5 JP 2000588357 A JP2000588357 A JP 2000588357A JP 2000588357 A JP2000588357 A JP 2000588357A JP 2002532094 A5 JP2002532094 A5 JP 2002532094A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- polynucleotide
- binds
- family member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 description 38
- 102000004196 processed proteins & peptides Human genes 0.000 description 36
- 229920001184 polypeptide Polymers 0.000 description 35
- 102000040430 polynucleotide Human genes 0.000 description 13
- 108091033319 polynucleotide Proteins 0.000 description 13
- 239000002157 polynucleotide Substances 0.000 description 13
- 239000012634 fragment Substances 0.000 description 7
- 102000014909 interleukin-1 receptor activity proteins Human genes 0.000 description 5
- 108040006732 interleukin-1 receptor activity proteins Proteins 0.000 description 5
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 4
- 239000012894 fetal calf serum Substances 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 238000002965 ELISA Methods 0.000 description 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 2
- 101000998122 Homo sapiens Interleukin-37 Proteins 0.000 description 2
- 102000039996 IL-1 family Human genes 0.000 description 2
- 108091069196 IL-1 family Proteins 0.000 description 2
- 102100033502 Interleukin-37 Human genes 0.000 description 2
- 102000003992 Peroxidases Human genes 0.000 description 2
- 239000013604 expression vector Substances 0.000 description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005497 microtitration Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 239000012898 sample dilution Substances 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11216398P | 1998-12-14 | 1998-12-14 | |
| US60/112,163 | 1998-12-14 | ||
| US16467599P | 1999-11-10 | 1999-11-10 | |
| US60/164,675 | 1999-11-10 | ||
| PCT/US1999/029549 WO2000036108A2 (en) | 1998-12-14 | 1999-12-14 | Il-1 zeta, il-1 zeta splice variants and xrec2 dnas and polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010127963A Division JP5081277B2 (ja) | 1998-12-14 | 2010-06-03 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002532094A JP2002532094A (ja) | 2002-10-02 |
| JP2002532094A5 true JP2002532094A5 (https=) | 2006-08-10 |
| JP4562287B2 JP4562287B2 (ja) | 2010-10-13 |
Family
ID=26809644
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000588357A Expired - Fee Related JP4562287B2 (ja) | 1998-12-14 | 1999-12-14 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
| JP2010127963A Expired - Fee Related JP5081277B2 (ja) | 1998-12-14 | 2010-06-03 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010127963A Expired - Fee Related JP5081277B2 (ja) | 1998-12-14 | 2010-06-03 | ＩＬ−１ゼータ、ＩＬ−１ゼータスプライス変異体およびＸｒｅｃ２のＤＮＡおよびポリペプチド |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1141298B1 (https=) |
| JP (2) | JP4562287B2 (https=) |
| AT (2) | ATE332374T1 (https=) |
| AU (2) | AU775128B2 (https=) |
| CA (2) | CA2642146C (https=) |
| CY (1) | CY1105405T1 (https=) |
| DE (2) | DE69940750D1 (https=) |
| DK (1) | DK1141298T3 (https=) |
| ES (2) | ES2267311T3 (https=) |
| IL (2) | IL143361A0 (https=) |
| NZ (1) | NZ512749A (https=) |
| PT (1) | PT1141298E (https=) |
| WO (1) | WO2000036108A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091181B2 (en) | 1994-12-12 | 2006-08-15 | Omeros Corporation | Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors |
| WO2000039297A2 (en) | 1998-12-23 | 2000-07-06 | Genentech, Inc. | Il-1 related polypeptides |
| EP1092773A3 (en) * | 1999-10-15 | 2001-08-08 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Polypeptide and uses thereof |
| JP2018522547A (ja) * | 2015-06-15 | 2018-08-16 | モナッシュ ユニバーシティ | Ｉｌ−３７バリアント |
| CN106540242B (zh) * | 2016-11-24 | 2019-09-17 | 中国医学科学院医学实验动物研究所 | IL-1F7a的作用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999006428A1 (en) * | 1997-08-04 | 1999-02-11 | Millennium Biotherapeutics, Inc. | Tango-72 and tango-77 nucleic acid molecules and polypeptides |
| AU751396B2 (en) * | 1997-08-04 | 2002-08-15 | Millennium Pharmaceuticals, Inc. | Novel molecules of the Tango-77 related protein family and uses thereof |
-
1999
- 1999-12-14 DE DE69940750T patent/DE69940750D1/de not_active Expired - Lifetime
- 1999-12-14 WO PCT/US1999/029549 patent/WO2000036108A2/en not_active Ceased
- 1999-12-14 IL IL14336199A patent/IL143361A0/xx active IP Right Grant
- 1999-12-14 AT AT99966182T patent/ATE332374T1/de not_active IP Right Cessation
- 1999-12-14 ES ES99966182T patent/ES2267311T3/es not_active Expired - Lifetime
- 1999-12-14 CA CA2642146A patent/CA2642146C/en not_active Expired - Fee Related
- 1999-12-14 PT PT99966182T patent/PT1141298E/pt unknown
- 1999-12-14 AT AT05025531T patent/ATE428726T1/de not_active IP Right Cessation
- 1999-12-14 JP JP2000588357A patent/JP4562287B2/ja not_active Expired - Fee Related
- 1999-12-14 NZ NZ512749A patent/NZ512749A/en unknown
- 1999-12-14 DE DE69932259T patent/DE69932259T2/de not_active Expired - Lifetime
- 1999-12-14 AU AU21788/00A patent/AU775128B2/en not_active Ceased
- 1999-12-14 DK DK99966182T patent/DK1141298T3/da active
- 1999-12-14 EP EP99966182A patent/EP1141298B1/en not_active Expired - Lifetime
- 1999-12-14 CA CA002353483A patent/CA2353483C/en not_active Expired - Fee Related
- 1999-12-14 ES ES05025531T patent/ES2325165T3/es not_active Expired - Lifetime
-
2001
- 2001-05-24 IL IL143361A patent/IL143361A/en not_active IP Right Cessation
-
2004
- 2004-10-07 AU AU2004218668A patent/AU2004218668B2/en not_active Ceased
-
2006
- 2006-09-26 CY CY20061101377T patent/CY1105405T1/el unknown
-
2010
- 2010-06-03 JP JP2010127963A patent/JP5081277B2/ja not_active Expired - Fee Related
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