JP2008517605A5 - - Google Patents
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- Publication number
- JP2008517605A5 JP2008517605A5 JP2007538172A JP2007538172A JP2008517605A5 JP 2008517605 A5 JP2008517605 A5 JP 2008517605A5 JP 2007538172 A JP2007538172 A JP 2007538172A JP 2007538172 A JP2007538172 A JP 2007538172A JP 2008517605 A5 JP2008517605 A5 JP 2008517605A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- cell
- polynucleotide
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 102000004196 processed proteins & peptides Human genes 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 102000004378 Melanocortin Receptors Human genes 0.000 claims 5
- 108090000950 Melanocortin Receptors Proteins 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 2
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 102000008316 Type 4 Melanocortin Receptor Human genes 0.000 claims 1
- 108010021436 Type 4 Melanocortin Receptor Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62196004P | 2004-10-25 | 2004-10-25 | |
| PCT/US2005/038431 WO2006047535A2 (en) | 2004-10-25 | 2005-10-25 | Melanocortin receptor binding mimetibodies, compositions, methods and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008517605A JP2008517605A (ja) | 2008-05-29 |
| JP2008517605A5 true JP2008517605A5 (https=) | 2008-11-20 |
Family
ID=36228385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007538172A Pending JP2008517605A (ja) | 2004-10-25 | 2005-10-25 | メラノコルチン受容体結合性ミメティボディ、組成物、方法および用途 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20060105951A1 (https=) |
| EP (1) | EP1812046B1 (https=) |
| JP (1) | JP2008517605A (https=) |
| KR (1) | KR101255140B1 (https=) |
| CN (1) | CN101437540B (https=) |
| AT (1) | ATE501731T1 (https=) |
| AU (1) | AU2005299440B2 (https=) |
| BR (1) | BRPI0518411A2 (https=) |
| CA (1) | CA2585287A1 (https=) |
| CY (1) | CY1111486T1 (https=) |
| DE (1) | DE602005026970D1 (https=) |
| DK (1) | DK1812046T3 (https=) |
| EA (1) | EA200700944A1 (https=) |
| EC (1) | ECSP077416A (https=) |
| ES (1) | ES2363023T3 (https=) |
| HR (1) | HRP20110405T1 (https=) |
| IL (1) | IL182683A0 (https=) |
| MA (1) | MA28943B1 (https=) |
| ME (1) | ME01234B (https=) |
| MX (1) | MX2007004974A (https=) |
| NO (1) | NO20072499L (https=) |
| PL (1) | PL1812046T3 (https=) |
| PT (1) | PT1812046E (https=) |
| RS (1) | RS51789B (https=) |
| SI (1) | SI1812046T1 (https=) |
| TN (1) | TNSN07157A1 (https=) |
| WO (1) | WO2006047535A2 (https=) |
| ZA (1) | ZA200704260B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7910101B2 (en) | 2004-10-25 | 2011-03-22 | Centocor, Inc. | Melanocortin receptor binding mimetibodies, compositions, methods and uses |
| US7790671B2 (en) * | 2005-10-07 | 2010-09-07 | Codman & Shurtleff, Inc. | Implantable pump for protein delivery for obesity control by drug infusion into the brain |
| WO2009151383A1 (en) * | 2008-06-09 | 2009-12-17 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides for the treatment of obesity and other diseases associated with melanocortin receptor function |
| KR101687037B1 (ko) | 2008-06-09 | 2016-12-15 | 팔라틴 테크놀로지스 인코포레이티드 | 성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드 |
| US8614185B2 (en) * | 2009-05-04 | 2013-12-24 | Centocor Ortho Biotech Inc. | Fusion proteins of alpha-MSH derivatives and Fc |
| EP2440572B1 (en) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Lactam-bridged melanocortin receptor-specific peptides |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| CA2761607C (en) | 2009-06-08 | 2018-09-04 | Yi-Qun Shi | Melanocortin receptor-specific peptides |
| BR112012011780A2 (pt) | 2009-11-23 | 2019-09-24 | Palatin Technologies, Inc | peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano |
| JP5999702B2 (ja) | 2009-11-23 | 2016-09-28 | パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. | メラノコルチン−１受容体特異的環状ペプチド |
| JP2020141710A (ja) * | 2011-07-06 | 2020-09-10 | ゲンマブ エー／エス | 抗体重鎖のｃ末端の修飾による補体依存性細胞傷害の調節 |
| WO2020177627A1 (zh) * | 2019-03-02 | 2020-09-10 | 上海一宸医药科技有限公司 | 一种双特异抗体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1137340A4 (en) * | 1998-12-09 | 2005-12-21 | Eleanor Roosevelt Inst | COMPOSITION AND METHODS FOR REGULATION OF BODY WEIGHT AND ASSOCIATED PATHOLOGIES |
| AU7593001A (en) * | 2000-07-14 | 2002-01-30 | Zycos Inc | Alpha-msh related compounds and methods of use |
| CA2490409A1 (en) * | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Mammalian ch1 deleted mimetibodies, compositions, methods and uses |
| US7241733B2 (en) * | 2002-06-28 | 2007-07-10 | Centocor, Inc. | Mammalian EPO mimetic CH1 deleted mimetibodies, compositions, methods and uses |
| US20070135338A1 (en) * | 2004-03-31 | 2007-06-14 | Karyn O'neil | Human GLP-1 mimetibodies, compositions, methods and uses |
-
2005
- 2005-10-25 RS RS20110230A patent/RS51789B/sr unknown
- 2005-10-25 BR BRPI0518411-8A patent/BRPI0518411A2/pt not_active IP Right Cessation
- 2005-10-25 HR HR20110405T patent/HRP20110405T1/hr unknown
- 2005-10-25 DK DK05819741.9T patent/DK1812046T3/da active
- 2005-10-25 CN CN2005800447902A patent/CN101437540B/zh not_active Expired - Fee Related
- 2005-10-25 MX MX2007004974A patent/MX2007004974A/es unknown
- 2005-10-25 PL PL05819741T patent/PL1812046T3/pl unknown
- 2005-10-25 EA EA200700944A patent/EA200700944A1/ru unknown
- 2005-10-25 AU AU2005299440A patent/AU2005299440B2/en not_active Ceased
- 2005-10-25 KR KR1020077011487A patent/KR101255140B1/ko not_active Expired - Fee Related
- 2005-10-25 ME MEP-2011-85A patent/ME01234B/me unknown
- 2005-10-25 PT PT05819741T patent/PT1812046E/pt unknown
- 2005-10-25 WO PCT/US2005/038431 patent/WO2006047535A2/en not_active Ceased
- 2005-10-25 JP JP2007538172A patent/JP2008517605A/ja active Pending
- 2005-10-25 US US11/257,851 patent/US20060105951A1/en not_active Abandoned
- 2005-10-25 AT AT05819741T patent/ATE501731T1/de active
- 2005-10-25 DE DE602005026970T patent/DE602005026970D1/de not_active Expired - Lifetime
- 2005-10-25 EP EP05819741A patent/EP1812046B1/en not_active Expired - Lifetime
- 2005-10-25 ES ES05819741T patent/ES2363023T3/es not_active Expired - Lifetime
- 2005-10-25 CA CA002585287A patent/CA2585287A1/en not_active Abandoned
- 2005-10-25 SI SI200531295T patent/SI1812046T1/sl unknown
-
2007
- 2007-04-19 IL IL182683A patent/IL182683A0/en unknown
- 2007-04-23 MA MA29843A patent/MA28943B1/fr unknown
- 2007-04-24 TN TNP2007000157A patent/TNSN07157A1/fr unknown
- 2007-04-25 EC EC2007007416A patent/ECSP077416A/es unknown
- 2007-05-15 NO NO20072499A patent/NO20072499L/no not_active Application Discontinuation
- 2007-05-24 ZA ZA200704260A patent/ZA200704260B/xx unknown
-
2011
- 2011-05-23 CY CY20111100502T patent/CY1111486T1/el unknown
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