JP2002531450A - パロキセチン・塩酸塩の製造方法 - Google Patents

パロキセチン・塩酸塩の製造方法

Info

Publication number
JP2002531450A
JP2002531450A JP2000585234A JP2000585234A JP2002531450A JP 2002531450 A JP2002531450 A JP 2002531450A JP 2000585234 A JP2000585234 A JP 2000585234A JP 2000585234 A JP2000585234 A JP 2000585234A JP 2002531450 A JP2002531450 A JP 2002531450A
Authority
JP
Japan
Prior art keywords
hydrochloride
propan
paroxetine
solvate
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000585234A
Other languages
English (en)
Japanese (ja)
Inventor
アンドリュー・サイモン・クレイグ
デイビッド・アラン・ジョーンズ
Original Assignee
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー filed Critical スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー
Publication of JP2002531450A publication Critical patent/JP2002531450A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2000585234A 1998-11-28 1999-11-26 パロキセチン・塩酸塩の製造方法 Pending JP2002531450A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9826176.1 1998-11-28
GBGB9826176.1A GB9826176D0 (en) 1998-11-28 1998-11-28 Novel process
PCT/GB1999/003968 WO2000032592A1 (fr) 1998-11-28 1999-11-26 Procede de fabrication d'hydrochlorure de paroxetine

Publications (1)

Publication Number Publication Date
JP2002531450A true JP2002531450A (ja) 2002-09-24

Family

ID=10843288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000585234A Pending JP2002531450A (ja) 1998-11-28 1999-11-26 パロキセチン・塩酸塩の製造方法

Country Status (5)

Country Link
EP (1) EP1133492A1 (fr)
JP (1) JP2002531450A (fr)
AU (1) AU1396600A (fr)
GB (1) GB9826176D0 (fr)
WO (1) WO2000032592A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
AR001982A1 (es) * 1995-02-06 1998-01-07 Smithkline Beecham Plc Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
DE69739561D1 (de) * 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
CA2187128A1 (fr) * 1996-10-04 1997-06-26 K. S. Keshava Murthy Polymorphe nouveau et efficace, a base de chlorhydrate de paroxetine anhydre

Also Published As

Publication number Publication date
EP1133492A1 (fr) 2001-09-19
WO2000032592A1 (fr) 2000-06-08
AU1396600A (en) 2000-06-19
GB9826176D0 (en) 1999-01-20

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