JP2002530063A5 - - Google Patents

Download PDF

Info

Publication number
JP2002530063A5
JP2002530063A5 JP2000582422A JP2000582422A JP2002530063A5 JP 2002530063 A5 JP2002530063 A5 JP 2002530063A5 JP 2000582422 A JP2000582422 A JP 2000582422A JP 2000582422 A JP2000582422 A JP 2000582422A JP 2002530063 A5 JP2002530063 A5 JP 2002530063A5
Authority
JP
Japan
Prior art keywords
hif
seq
human
mutant
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000582422A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002530063A (ja
Filing date
Publication date
Priority claimed from SE9803891A external-priority patent/SE9803891D0/xx
Application filed filed Critical
Publication of JP2002530063A publication Critical patent/JP2002530063A/ja
Publication of JP2002530063A5 publication Critical patent/JP2002530063A5/ja
Pending legal-status Critical Current

Links

JP2000582422A 1998-11-13 1999-11-11 低酸素誘導性因子1α(HIF−1α)変異体およびHIF−1α調整因子の同定法 Pending JP2002530063A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803891A SE9803891D0 (sv) 1998-11-13 1998-11-13 Protein Variants
SE9803891-2 1998-11-13
PCT/SE1999/002053 WO2000029437A1 (en) 1998-11-13 1999-11-11 HYPOXIA-INDUCIBLE FACTOR 1α HIF-1α VARIANTS AND METHODS FOR IDENTIFYING HIF-1α MODULATORS

Publications (2)

Publication Number Publication Date
JP2002530063A JP2002530063A (ja) 2002-09-17
JP2002530063A5 true JP2002530063A5 (https=) 2006-12-14

Family

ID=20413284

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000582422A Pending JP2002530063A (ja) 1998-11-13 1999-11-11 低酸素誘導性因子1α(HIF−1α)変異体およびHIF−1α調整因子の同定法

Country Status (15)

Country Link
EP (1) EP1141005B1 (https=)
JP (1) JP2002530063A (https=)
KR (1) KR100648761B1 (https=)
CN (1) CN1330666C (https=)
AT (1) ATE374210T1 (https=)
AU (1) AU761594B2 (https=)
BR (1) BR9915263A (https=)
CA (1) CA2350830A1 (https=)
DE (1) DE69937199D1 (https=)
HK (1) HK1043372B (https=)
NZ (1) NZ511450A (https=)
SE (1) SE9803891D0 (https=)
TR (1) TR200101345T2 (https=)
WO (1) WO2000029437A1 (https=)
ZA (1) ZA200103669B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9911047D0 (en) 1999-05-12 1999-07-14 Isis Innovation Assay method and means
ATE383877T1 (de) * 1999-06-04 2008-02-15 Dana Farber Cancer Inst Inc Identifikation von stoffen, die transkriptionelle antworten auf hypoxia modifizieren
WO2001092578A2 (en) * 2000-05-26 2001-12-06 Board Of Trustees Of The University Of Illinois Reagents and methods for identifying and modulating expression of genes regulated by retinoids
AU9017901A (en) * 2000-08-07 2002-02-18 Angiogenetics Sweden Ab Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the vonhippel-lindau tumor suppressor protein
US20030045830A1 (en) * 2001-04-17 2003-03-06 De Bizemont Therese Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis
AU2002302252A1 (en) 2001-05-23 2002-12-03 Angiogene Inc. Hypoxia inducible factors and uses thereof for inducing angiogenesis and improving muscular functions
EP1842856A3 (en) * 2001-05-23 2007-12-12 Angiogene Inc. Hypoxia inducing factors and uses thereof for inducing angiogenesis and improving muscular functions
AU2003201798A1 (en) * 2002-01-11 2003-09-02 Angio Genetics Sweden Ab Hif-1 alpha proteins mutated in the c-terminal transactivation domain
CN100366747C (zh) * 2005-03-08 2008-02-06 上海第二医科大学附属仁济医院 低氧诱导因子小干扰rna质粒
CN100418574C (zh) * 2005-10-26 2008-09-17 王成球 一类封闭人类HIF-1α基因和调控网络中下游相关基因的染色质肽
CN102127161B (zh) * 2010-12-16 2013-03-27 何明忠 抗肿瘤多肽及其用途
CN106366173A (zh) * 2015-07-24 2017-02-01 北京京爱康科技有限公司 一种通过结合低氧反应元件控制缺氧反应基因表达的染色质肽

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5882914A (en) * 1995-06-06 1999-03-16 The Johns Hopkins University School Of Medicine Nucleic acids encoding the hypoxia inducible factor-1

Similar Documents

Publication Publication Date Title
Kamachi et al. Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1-crystallin enhancer
Nambu et al. The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1α and Drosophila single-minded
Qyang et al. Cell-type-dependent activity of the ubiquitous transcription factor USF in cellular proliferation and transcriptional activation
Haycraft et al. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
Liu et al. Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro
Webster et al. The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator
Jones et al. Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro
Keller et al. Identification of an inducible factor that binds to a positive regulatory element of the human beta-interferon gene.
JP2002530063A5 (https=)
Funahashi et al. Identification of nuclear factor δEF1 and its binding site essential for lens-specific activity of the δ1-crystallin enhancer
Larkin et al. Flanking sequences modulate the cell specificity of M-CAT elements
WO1995026400A1 (en) Reverse two-hybrid method
ATE301188T1 (de) Reprimiertes trans-aktivatorsystem zur charakterisierung von protein-protein interaktionen
Gandelman et al. Species and regional differences in the expression of cell‐type specific elements at the human and rat tyrosine hydroxylase gene loci
Kojima et al. Transcriptional activation domain of human BTEB2, a GC box-binding factor
Maitra et al. Differentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene expression
Pederson et al. Regulation by homeoproteins: a comparison of deformed-responsive elements
Carr et al. Protein-DNA interactions in the 5′ region of the mouse alcohol dehydrogenase gene Adh-1
Chau et al. RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct
WO1991016456A1 (en) Screening assays for compounds which inhibit the binding of c-myc to dna
AU2002234729B2 (en) Method for identifying compounds modulating reverse cholesterol transport
Kou et al. Structural and functional analysis of mutations along the crystallographic dimer interface of the yeast TATA binding protein
Kagaya et al. Cloning and characterization of the 5′-flanking region of human cytokeratin 19 gene in human cholangiocarcinoma cell line
JP5532478B2 (ja) ドメインタンパク質を用いた医薬品候補の検索方法
Gaston et al. The isolation of transcription factors from λgt11 cDNA expression libraries: human steroid 5α-reductase 1 has sequence-specific DNA binding activity