JP2002525066A - 核酸の特異的な細胞の局在化のための転写法 - Google Patents

核酸の特異的な細胞の局在化のための転写法

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Publication number
JP2002525066A
JP2002525066A JP2000570351A JP2000570351A JP2002525066A JP 2002525066 A JP2002525066 A JP 2002525066A JP 2000570351 A JP2000570351 A JP 2000570351A JP 2000570351 A JP2000570351 A JP 2000570351A JP 2002525066 A JP2002525066 A JP 2002525066A
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JP
Japan
Prior art keywords
nucleic acid
pna
interest
carrier
nls
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000570351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002525066A5 (https=
Inventor
ブランデン、ラース
モハメッド、アブダラ、ジェイ
スミス、シー．，アイ．，エドワード
Original Assignee
カロリンスカ イノヴェーション アーベー
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Application filed by カロリンスカ イノヴェーション アーベー filed Critical カロリンスカ イノヴェーション アーベー
Publication of JP2002525066A publication Critical patent/JP2002525066A/ja
Publication of JP2002525066A5 publication Critical patent/JP2002525066A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000570351A 1998-09-13 1999-03-15 核酸の特異的な細胞の局在化のための転写法 Pending JP2002525066A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803099-2 1998-09-13
SE9803099A SE9803099D0 (sv) 1998-09-13 1998-09-13 Nucleic acid transfer
PCT/SE1999/000398 WO2000015824A1 (en) 1998-09-13 1999-03-15 Transfer method for specific cellular localisation of nucleic acids

Publications (2)

Publication Number Publication Date
JP2002525066A true JP2002525066A (ja) 2002-08-13
JP2002525066A5 JP2002525066A5 (https=) 2006-08-17

Family

ID=20412578

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000570351A Pending JP2002525066A (ja) 1998-09-13 1999-03-15 核酸の特異的な細胞の局在化のための転写法

Country Status (9)

Country Link
US (1) US6720310B1 (https=)
EP (1) EP1114172B1 (https=)
JP (1) JP2002525066A (https=)
AT (1) ATE435918T1 (https=)
AU (1) AU3178499A (https=)
DE (1) DE69941089D1 (https=)
DK (1) DK1114172T3 (https=)
SE (1) SE9803099D0 (https=)
WO (1) WO2000015824A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008527993A (ja) * 2005-01-24 2008-07-31 アヴァリス・アクチエボラーグ 特異性及び送達の改善のためのｓｉＲＮＡ分子、ｓｈＲＮＡ分子又はアンチセンス分子及び機能的実体を含む複合体

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
US6312956B1 (en) * 1999-10-01 2001-11-06 Vanderbilt University Nuclear targeted peptide nucleic acid oligomer
EP1235914A2 (en) * 1999-11-24 2002-09-04 Joseph Rosenecker Polypeptides comprising multimers of nuclear localization signals or of protein transduction domains and their use for transferring molecules into cells
KR100374050B1 (ko) * 2000-07-26 2003-03-03 최수영 세포침투성 융합단백질, 이를 코딩하는 재조합폴리뉴클레오타이드 및 발현벡터
KR100420798B1 (ko) 2001-02-10 2004-03-02 (주)알에이싸이언스 펩타이드 벡터
SE0200531D0 (sv) * 2002-02-22 2002-02-22 Avaris Ab Novel biomolecular complexes, method for their production and use
SE0201234D0 (sv) * 2002-04-24 2002-04-24 Avaris Ab Transfer complex with added functionality and methods for its use
DE10393824D2 (de) * 2002-09-23 2005-08-11 Mologen Ag Impfstoff gegen Infektionen mit Onkoviren, wie dem felinen Leukosevirus der Katze
WO2005052166A1 (en) * 2003-11-29 2005-06-09 Young-Jin Chae Recombinant peptide vector comprising the gene for treatment for autoimmune diseases.
US7795380B2 (en) * 2006-06-02 2010-09-14 University Of Iowa Research Foundation Compositions and methods for nucleic acid delivery
EP1900820A1 (en) * 2006-09-13 2008-03-19 Amaxa AG Nuclear transport agent and method for producing said agent
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
HUE037408T2 (hu) 2011-06-10 2018-08-28 Univ Oregon Health & Science CMV glikoproteinek és rekombináns vektorok
CA2789539A1 (en) 2011-09-12 2013-03-12 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CZ308738B6 (cs) * 2020-01-20 2021-04-14 PortalGene s.r.o. Způsob úpravy molekuly nukleové kyseliny pro usnadění jejího přenosu do hostitelských buněk a upravená molekula nukleové kyseliny

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO1996040961A1 (en) * 1995-06-07 1996-12-19 Life Technologies, Inc. Peptide-enhanced cationic lipid transfections
JP2001516562A (ja) * 1997-09-18 2001-10-02 ジーン セラピー システムズ インコーポレーテッド ペプチド核酸コンジュゲートを用いたｄｎａの化学修飾

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NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4274149A (en) 1980-02-19 1981-06-16 Flanagan Charles E Binocular device for displaying elapsed time in the field of view
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5265003A (en) 1990-07-25 1993-11-23 Power Trends Miniaturized switching power supply with programmed level gate drive
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5641625A (en) 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
DE69233046T2 (de) 1991-10-24 2004-03-04 Isis Pharmaceuticals, Inc., Carlsfeld Derivatisierte oligonukleotide mit verbessertem aufnahmevermögen
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
WO1993019768A1 (en) * 1992-04-03 1993-10-14 The Regents Of The University Of California Self-assembling polynucleotide delivery system
AU3999495A (en) 1994-10-06 1996-05-02 Buchardt, Dorte Peptide nucleic acid conjugates
US6051429A (en) 1995-06-07 2000-04-18 Life Technologies, Inc. Peptide-enhanced cationic lipid transfections
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
US6312956B1 (en) * 1999-10-01 2001-11-06 Vanderbilt University Nuclear targeted peptide nucleic acid oligomer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040961A1 (en) * 1995-06-07 1996-12-19 Life Technologies, Inc. Peptide-enhanced cationic lipid transfections
JP2001516562A (ja) * 1997-09-18 2001-10-02 ジーン セラピー システムズ インコーポレーテッド ペプチド核酸コンジュゲートを用いたｄｎａの化学修飾

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008527993A (ja) * 2005-01-24 2008-07-31 アヴァリス・アクチエボラーグ 特異性及び送達の改善のためのｓｉＲＮＡ分子、ｓｈＲＮＡ分子又はアンチセンス分子及び機能的実体を含む複合体

Also Published As

Publication number Publication date
SE9803099D0 (sv) 1998-09-13
US6720310B1 (en) 2004-04-13
DK1114172T3 (da) 2009-11-09
DE69941089D1 (de) 2009-08-20
EP1114172A1 (en) 2001-07-11
AU3178499A (en) 2000-04-03
EP1114172B1 (en) 2009-07-08
WO2000015824A1 (en) 2000-03-23
ATE435918T1 (de) 2009-07-15

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