SE9803099D0 - Nucleic acid transfer - Google Patents
Nucleic acid transferInfo
- Publication number
- SE9803099D0 SE9803099D0 SE9803099A SE9803099A SE9803099D0 SE 9803099 D0 SE9803099 D0 SE 9803099D0 SE 9803099 A SE9803099 A SE 9803099A SE 9803099 A SE9803099 A SE 9803099A SE 9803099 D0 SE9803099 D0 SE 9803099D0
- Authority
- SE
- Sweden
- Prior art keywords
- nucleic acid
- interest
- peptide
- present
- protein
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 5
- 102000039446 nucleic acids Human genes 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 108010077850 Nuclear Localization Signals Proteins 0.000 abstract 2
- 108091093037 Peptide nucleic acid Proteins 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 230000032258 transport Effects 0.000 abstract 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000025308 nuclear transport Effects 0.000 abstract 1
- MCYTYTUNNNZWOK-LCLOTLQISA-N penetratin Chemical compound C([C@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCNC(N)=N)[C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CC=CC=C1 MCYTYTUNNNZWOK-LCLOTLQISA-N 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000006798 recombination Effects 0.000 abstract 1
- 230000005945 translocation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9803099A SE9803099D0 (sv) | 1998-09-13 | 1998-09-13 | Nucleic acid transfer |
| EP99913793A EP1114172B1 (en) | 1998-09-13 | 1999-03-15 | Transfer method for specific cellular localisation of nucleic acids |
| AU31784/99A AU3178499A (en) | 1998-09-13 | 1999-03-15 | Transfer method for specific cellular localisation of nucleic acids |
| DK99913793T DK1114172T3 (da) | 1998-09-13 | 1999-03-15 | Overförselsfremgangsmåde til specifik cellulær lokalisering af nukleinsyrer |
| DE69941089T DE69941089D1 (de) | 1998-09-13 | 1999-03-15 | Transferverfahren für die spezifische zelluläre lokalisation von nukleinsäuren |
| PCT/SE1999/000398 WO2000015824A1 (en) | 1998-09-13 | 1999-03-15 | Transfer method for specific cellular localisation of nucleic acids |
| JP2000570351A JP2002525066A (ja) | 1998-09-13 | 1999-03-15 | 核酸の特異的な細胞の局在化のための転写法 |
| US09/787,033 US6720310B1 (en) | 1998-09-13 | 1999-03-15 | Transfer method for specific cellular localization of nucleic acids |
| AT99913793T ATE435918T1 (de) | 1998-09-13 | 1999-03-15 | Transferverfahren für die spezifische zelluläre lokalisation von nukleinsäuren |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9803099A SE9803099D0 (sv) | 1998-09-13 | 1998-09-13 | Nucleic acid transfer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9803099D0 true SE9803099D0 (sv) | 1998-09-13 |
Family
ID=20412578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9803099A SE9803099D0 (sv) | 1998-09-13 | 1998-09-13 | Nucleic acid transfer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6720310B1 (https=) |
| EP (1) | EP1114172B1 (https=) |
| JP (1) | JP2002525066A (https=) |
| AT (1) | ATE435918T1 (https=) |
| AU (1) | AU3178499A (https=) |
| DE (1) | DE69941089D1 (https=) |
| DK (1) | DK1114172T3 (https=) |
| SE (1) | SE9803099D0 (https=) |
| WO (1) | WO2000015824A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9803099D0 (sv) | 1998-09-13 | 1998-09-13 | Karolinska Innovations Ab | Nucleic acid transfer |
| US6312956B1 (en) * | 1999-10-01 | 2001-11-06 | Vanderbilt University | Nuclear targeted peptide nucleic acid oligomer |
| EP1235914A2 (en) * | 1999-11-24 | 2002-09-04 | Joseph Rosenecker | Polypeptides comprising multimers of nuclear localization signals or of protein transduction domains and their use for transferring molecules into cells |
| KR100374050B1 (ko) * | 2000-07-26 | 2003-03-03 | 최수영 | 세포침투성 융합단백질, 이를 코딩하는 재조합폴리뉴클레오타이드 및 발현벡터 |
| KR100420798B1 (ko) | 2001-02-10 | 2004-03-02 | (주)알에이싸이언스 | 펩타이드 벡터 |
| SE0200531D0 (sv) * | 2002-02-22 | 2002-02-22 | Avaris Ab | Novel biomolecular complexes, method for their production and use |
| SE0201234D0 (sv) * | 2002-04-24 | 2002-04-24 | Avaris Ab | Transfer complex with added functionality and methods for its use |
| DE10393824D2 (de) * | 2002-09-23 | 2005-08-11 | Mologen Ag | Impfstoff gegen Infektionen mit Onkoviren, wie dem felinen Leukosevirus der Katze |
| WO2005052166A1 (en) * | 2003-11-29 | 2005-06-09 | Young-Jin Chae | Recombinant peptide vector comprising the gene for treatment for autoimmune diseases. |
| US20080206869A1 (en) * | 2005-01-24 | 2008-08-28 | Avaris Ab | Nucleic Acid Complex |
| US7795380B2 (en) * | 2006-06-02 | 2010-09-14 | University Of Iowa Research Foundation | Compositions and methods for nucleic acid delivery |
| EP1900820A1 (en) * | 2006-09-13 | 2008-03-19 | Amaxa AG | Nuclear transport agent and method for producing said agent |
| AU2011230619C1 (en) | 2010-03-25 | 2016-06-23 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
| HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
| CA2789539A1 (en) | 2011-09-12 | 2013-03-12 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
| ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| CZ308738B6 (cs) * | 2020-01-20 | 2021-04-14 | PortalGene s.r.o. | Způsob úpravy molekuly nukleové kyseliny pro usnadění jejího přenosu do hostitelských buněk a upravená molekula nukleové kyseliny |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4274149A (en) | 1980-02-19 | 1981-06-16 | Flanagan Charles E | Binocular device for displaying elapsed time in the field of view |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US5265003A (en) | 1990-07-25 | 1993-11-23 | Power Trends | Miniaturized switching power supply with programmed level gate drive |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5641625A (en) | 1992-05-22 | 1997-06-24 | Isis Pharmaceuticals, Inc. | Cleaving double-stranded DNA with peptide nucleic acids |
| DE69233046T2 (de) | 1991-10-24 | 2004-03-04 | Isis Pharmaceuticals, Inc., Carlsfeld | Derivatisierte oligonukleotide mit verbessertem aufnahmevermögen |
| US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| WO1993019768A1 (en) * | 1992-04-03 | 1993-10-14 | The Regents Of The University Of California | Self-assembling polynucleotide delivery system |
| AU3999495A (en) | 1994-10-06 | 1996-05-02 | Buchardt, Dorte | Peptide nucleic acid conjugates |
| EP0874910A4 (en) | 1995-06-07 | 1999-04-21 | Life Technologies Inc | ENHANCED CATIONIC LIPID TRANSFECTION BY PEPTIDES |
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| AU9570898A (en) * | 1997-09-18 | 1999-04-05 | Gene Therapy Systems, Inc. | Chemical modification of dna using peptide nucleic acid conjugates |
| SE9803099D0 (sv) | 1998-09-13 | 1998-09-13 | Karolinska Innovations Ab | Nucleic acid transfer |
| US6312956B1 (en) * | 1999-10-01 | 2001-11-06 | Vanderbilt University | Nuclear targeted peptide nucleic acid oligomer |
-
1998
- 1998-09-13 SE SE9803099A patent/SE9803099D0/xx unknown
-
1999
- 1999-03-15 WO PCT/SE1999/000398 patent/WO2000015824A1/en not_active Ceased
- 1999-03-15 AT AT99913793T patent/ATE435918T1/de not_active IP Right Cessation
- 1999-03-15 DK DK99913793T patent/DK1114172T3/da active
- 1999-03-15 US US09/787,033 patent/US6720310B1/en not_active Expired - Fee Related
- 1999-03-15 DE DE69941089T patent/DE69941089D1/de not_active Expired - Lifetime
- 1999-03-15 AU AU31784/99A patent/AU3178499A/en not_active Abandoned
- 1999-03-15 EP EP99913793A patent/EP1114172B1/en not_active Expired - Lifetime
- 1999-03-15 JP JP2000570351A patent/JP2002525066A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6720310B1 (en) | 2004-04-13 |
| DK1114172T3 (da) | 2009-11-09 |
| DE69941089D1 (de) | 2009-08-20 |
| EP1114172A1 (en) | 2001-07-11 |
| AU3178499A (en) | 2000-04-03 |
| EP1114172B1 (en) | 2009-07-08 |
| WO2000015824A1 (en) | 2000-03-23 |
| JP2002525066A (ja) | 2002-08-13 |
| ATE435918T1 (de) | 2009-07-15 |
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