JP2002524417A5 - - Google Patents
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- Publication number
- JP2002524417A5 JP2002524417A5 JP2000568497A JP2000568497A JP2002524417A5 JP 2002524417 A5 JP2002524417 A5 JP 2002524417A5 JP 2000568497 A JP2000568497 A JP 2000568497A JP 2000568497 A JP2000568497 A JP 2000568497A JP 2002524417 A5 JP2002524417 A5 JP 2002524417A5
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- lysophosphatidylcholine
- monoglyceride
- acid ester
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000014113 dietary fatty acids Nutrition 0.000 description 43
- 229930195729 fatty acid Natural products 0.000 description 43
- 239000000194 fatty acid Substances 0.000 description 43
- -1 diglyceride Chemical compound 0.000 description 28
- RYCNUMLMNKHWPZ-SNVBAGLBSA-N 1-acetyl-sn-glycero-3-phosphocholine Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C RYCNUMLMNKHWPZ-SNVBAGLBSA-N 0.000 description 24
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 22
- 150000004665 fatty acids Chemical class 0.000 description 22
- 238000000034 method Methods 0.000 description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 21
- 239000003814 drug Substances 0.000 description 14
- 239000000203 mixture Substances 0.000 description 13
- 150000002632 lipids Chemical class 0.000 description 11
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 description 9
- 102000015439 Phospholipases Human genes 0.000 description 9
- 108010064785 Phospholipases Proteins 0.000 description 9
- 229940079593 drug Drugs 0.000 description 9
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 8
- 229930006000 Sucrose Natural products 0.000 description 7
- 150000001840 cholesterol esters Chemical class 0.000 description 7
- 229920000223 polyglycerol Polymers 0.000 description 7
- 239000005720 sucrose Substances 0.000 description 7
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 7
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 4
- 206010025476 Malabsorption Diseases 0.000 description 3
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 3
- 235000012000 cholesterol Nutrition 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9943098P | 1998-09-08 | 1998-09-08 | |
| US60/099,430 | 1998-09-08 | ||
| PCT/US1999/020427 WO2000013689A1 (en) | 1998-09-08 | 1999-09-07 | Methods and compositions for increasing intestinal absorption of fats |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002524417A JP2002524417A (ja) | 2002-08-06 |
| JP2002524417A5 true JP2002524417A5 (https=) | 2006-11-02 |
| JP4700193B2 JP4700193B2 (ja) | 2011-06-15 |
Family
ID=22274976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000568497A Expired - Fee Related JP4700193B2 (ja) | 1998-09-08 | 1999-09-07 | 脂肪の腸吸収を増加させるための方法および組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6426069B1 (https=) |
| EP (1) | EP1119360B1 (https=) |
| JP (1) | JP4700193B2 (https=) |
| CN (1) | CN1321089A (https=) |
| AT (1) | ATE347371T1 (https=) |
| AU (1) | AU771901B2 (https=) |
| CA (1) | CA2343116C (https=) |
| DE (1) | DE69934325T2 (https=) |
| IL (2) | IL141801A0 (https=) |
| NO (1) | NO20011173L (https=) |
| NZ (1) | NZ510536A (https=) |
| WO (1) | WO2000013689A1 (https=) |
| ZA (1) | ZA200102268B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL161178A0 (en) * | 2001-10-11 | 2004-08-31 | Biomolecular Products Inc | MODIFICATIONS OF SOLID 3-sn-PHOSPHOGLYCERIDES |
| DE60238663D1 (de) | 2002-04-05 | 2011-02-03 | Nestle Sa | Zusammensetzungen und Verfahren zur Verbesserung von Lipidassimilation in Haustieren |
| DE10217555A1 (de) * | 2002-04-19 | 2004-02-19 | Degussa Bioactives Deutschland Gmbh | Physiologisch verträgliche, Phospholipid-haltige, stabile und harte Matrix |
| JP2006518384A (ja) * | 2003-01-31 | 2006-08-10 | チルドレンズ・ホスピタル・ロス・アンジエルス | 改善されたバイオアベイラビリティを有するフェンレチニドの経口組成物、およびその使用方法 |
| US7758884B2 (en) * | 2005-01-28 | 2010-07-20 | Kemin Industries, Inc. | Formulation for increasing the deposition of dietary carotenoids in eggs |
| EP1688049A1 (de) * | 2005-02-03 | 2006-08-09 | findusFit Sportdiätetika GmbH | Diätetisches Lebensmittel |
| FR2918846B1 (fr) * | 2007-07-20 | 2013-07-26 | Isl Innovation Sante Lipides | Composition alimentaire pour ameliorer la digestibilite des lipides alimentaires |
| US10463229B2 (en) * | 2010-10-22 | 2019-11-05 | Fukuoka University | Endoscopic observation method and composition for improving diagnostic performance involving applying useful white opaque substance to diagnosis of gastric epithelial tumors (adenoma or gastric cancer) |
| CA2817957C (en) * | 2010-11-15 | 2016-05-10 | Texas Tech University | Substance for increasing the production of a specific acyl-chain dihydroceramide(s) for improving the effectiveness of cancer treatments |
| AU2019342421B2 (en) * | 2018-09-21 | 2024-09-05 | Société des Produits Nestlé S.A. | Compositions and methods for treatment of exocrine pancreatic insufficiency (EPI) |
| WO2025148196A1 (zh) * | 2024-01-12 | 2025-07-17 | 小藻科技(安吉)有限公司 | 一种促进脂肪酸吸收及跨越血脑屏障的微藻提取物及其组合物的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874795A (en) * | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| US4849132A (en) | 1986-05-16 | 1989-07-18 | Asahi Denka Kogyo Kabushiki Kaisha | Surfactant composition having improved functions |
| US5571517A (en) | 1990-08-13 | 1996-11-05 | Yesair; David W. | Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories |
| ES2071332T3 (es) | 1990-08-13 | 1995-06-16 | David W Yesair | Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. |
| US5302400A (en) * | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
| JPH08143469A (ja) * | 1994-11-14 | 1996-06-04 | Amano Pharmaceut Co Ltd | 膵外分泌機能不全症治療剤 |
| JPH11506780A (ja) * | 1995-06-06 | 1999-06-15 | バイオモレキュラー プロダクツ，インク． | 薬またはカロリー送達用の混合脂質−重炭酸塩コロイド粒子 |
| US5716814A (en) | 1996-02-02 | 1998-02-10 | Biomolecular Products, Inc. | Methods for making lysophosphatidylcholine |
| WO1998010776A1 (en) * | 1996-09-11 | 1998-03-19 | Shanahan Prendergast Elizabeth | Therapeutic formulations containing venom or venom anti-serum either alone or in combination for the therapeutic prophylaxis and therapy of neoplasms |
-
1999
- 1999-09-07 DE DE69934325T patent/DE69934325T2/de not_active Expired - Lifetime
- 1999-09-07 AU AU57052/99A patent/AU771901B2/en not_active Ceased
- 1999-09-07 NZ NZ510536A patent/NZ510536A/en not_active IP Right Cessation
- 1999-09-07 AT AT99944090T patent/ATE347371T1/de not_active IP Right Cessation
- 1999-09-07 CA CA002343116A patent/CA2343116C/en not_active Expired - Fee Related
- 1999-09-07 IL IL14180199A patent/IL141801A0/xx active IP Right Grant
- 1999-09-07 JP JP2000568497A patent/JP4700193B2/ja not_active Expired - Fee Related
- 1999-09-07 US US09/786,695 patent/US6426069B1/en not_active Expired - Lifetime
- 1999-09-07 WO PCT/US1999/020427 patent/WO2000013689A1/en not_active Ceased
- 1999-09-07 ZA ZA200102268A patent/ZA200102268B/en unknown
- 1999-09-07 CN CN99811075A patent/CN1321089A/zh active Pending
- 1999-09-07 EP EP99944090A patent/EP1119360B1/en not_active Expired - Lifetime
-
2001
- 2001-03-04 IL IL141801A patent/IL141801A/en not_active IP Right Cessation
- 2001-03-07 NO NO20011173A patent/NO20011173L/no not_active Application Discontinuation
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