JP2002523400A5 - - Google Patents
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- Publication number
- JP2002523400A5 JP2002523400A5 JP2000566249A JP2000566249A JP2002523400A5 JP 2002523400 A5 JP2002523400 A5 JP 2002523400A5 JP 2000566249 A JP2000566249 A JP 2000566249A JP 2000566249 A JP2000566249 A JP 2000566249A JP 2002523400 A5 JP2002523400 A5 JP 2002523400A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- hydrogen atom
- pharmaceutically acceptable
- alkyl
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10-234643 | 1998-08-20 | ||
| JP23464398 | 1998-08-20 | ||
| PCT/JP1999/004443 WO2000010975A1 (en) | 1998-08-20 | 1999-08-18 | Oxindole derivatives as growth hormone releasers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002523400A JP2002523400A (ja) | 2002-07-30 |
| JP2002523400A5 true JP2002523400A5 (https=) | 2006-07-27 |
| JP4445133B2 JP4445133B2 (ja) | 2010-04-07 |
Family
ID=16974248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000566249A Expired - Fee Related JP4445133B2 (ja) | 1998-08-20 | 1999-08-18 | オキシインドール誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6576656B1 (https=) |
| EP (1) | EP1105376B1 (https=) |
| JP (1) | JP4445133B2 (https=) |
| KR (1) | KR100680085B1 (https=) |
| CN (1) | CN1161333C (https=) |
| AT (1) | ATE288895T1 (https=) |
| AU (1) | AU5301199A (https=) |
| CA (1) | CA2340701C (https=) |
| DE (1) | DE69923692T2 (https=) |
| ES (1) | ES2237135T3 (https=) |
| WO (1) | WO2000010975A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60115227T2 (de) * | 2000-05-11 | 2006-08-24 | Bristol-Myers Squibb Co. | Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga |
| EP1364945A4 (en) * | 2001-01-30 | 2005-08-31 | Sumitomo Pharma | BENZIMIDAZOLIDINONDERIVATE |
| AU2002357692A1 (en) | 2001-11-09 | 2003-05-26 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
| SE0104341D0 (sv) * | 2001-12-20 | 2001-12-20 | Astrazeneca Ab | New use |
| SE0104340D0 (sv) * | 2001-12-20 | 2001-12-20 | Astrazeneca Ab | New compounds |
| TW200301123A (en) * | 2001-12-21 | 2003-07-01 | Astrazeneca Uk Ltd | New use |
| EP1458711B1 (en) * | 2001-12-21 | 2007-07-18 | AstraZeneca AB | Use of oxindole derivatives in the treatment of dementia related diseases, alzheimer s disease and conditions associated with glycogen synthase kinase-3 |
| SE0200979D0 (sv) | 2002-03-28 | 2002-03-28 | Astrazeneca Ab | New compounds |
| KR100755625B1 (ko) | 2002-10-24 | 2007-09-04 | 화이자 프로덕츠 인크. | 신경이완 활성을 갖는 5-(2-(4-(1,2벤즈이소티아졸-3-일)-1-피페라지닐)에틸)-6-클로로-1,3-디히드로-2ｈ-인돌-2-온의 아실 유도체 |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| US6912165B2 (en) * | 2003-08-22 | 2005-06-28 | International Business Machines Corporation | Method for transparent updates of output driver impedance |
| JPWO2005035498A1 (ja) * | 2003-10-08 | 2006-12-21 | 住友製薬株式会社 | 含窒素二環性化合物の摂食調節剤としての用途 |
| WO2006023608A2 (en) | 2004-08-18 | 2006-03-02 | Elixir Pharmaceuticals, Inc. | Growth-hormone secretagogues |
| JPWO2007032371A1 (ja) | 2005-09-14 | 2009-03-19 | 大日本住友製薬株式会社 | 摂食調節剤としてのオキシインドール誘導体 |
| CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| KR20090107088A (ko) | 2007-02-09 | 2009-10-12 | 트랜자임 파르마 인크 | 거대고리 그렐린 수용체 조절제 및 이의 사용 방법 |
| FR2920023B1 (fr) * | 2007-08-16 | 2013-02-08 | Sanofi Aventis | Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique |
| AU2009263037B2 (en) * | 2008-06-26 | 2011-10-06 | Amgen Inc. | Alkynyl alcohols as kinase inhibitors |
| FR2941947B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one subtitues en 3, leur preparation et leur application en therapeutique |
| FR2941946B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| EP2246326A1 (de) * | 2009-05-02 | 2010-11-03 | Bayer CropScience AG | Verfahren zur Herstellung von Oxindolen und ortho-substituierten Anilinen und ihre Verwendung als Zwischenprodukte für Synthesen |
| EP3153167B1 (en) | 2011-10-28 | 2019-10-02 | Vanderbilt University | Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m1 |
| WO2013071201A1 (en) | 2011-11-11 | 2013-05-16 | Vanderbilt University | Substituted benzylspiroindolin-2-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m1 |
| US9029563B2 (en) | 2012-01-06 | 2015-05-12 | Vanderbilt University | Substituted 1-benzylindolin-2-one analogs as positive allosteric modulators of muscarinic acetylcholine M1 receptors |
| US8697888B2 (en) * | 2012-01-06 | 2014-04-15 | Vanderbilt University | Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors |
| WO2013106795A1 (en) | 2012-01-12 | 2013-07-18 | Vanderbilt University | Substituted 4-(1h~pyrazol-4.yl)benzyl analogues as positive allosteric modulators of machr m1 receptors |
| WO2014065341A1 (ja) | 2012-10-24 | 2014-05-01 | 第一三共株式会社 | 筋萎縮性側索硬化症治療剤 |
| CN119409618B (zh) * | 2024-09-30 | 2025-10-10 | 厦门大学 | 一种吲哚衍生物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB125671A (en) | 1917-07-03 | 1919-05-01 | James Rossiter Hoyle | Improvements in or relating to Armour Piercing Projectiles. |
| US3441570A (en) * | 1966-01-20 | 1969-04-29 | Parke Davis & Co | 3-tertiary aminoalkylamino-3-phenyl oxindole compounds |
| US3891644A (en) * | 1971-01-11 | 1975-06-24 | Wyeth John & Brother Ltd | 10,10-Disubstituted-2,3,4,10-tetrahydro-and 1,2,3,4,10a-hexahydropyrimidol {8 1,2-a{9 indole derivatives |
| GB1450137A (en) | 1973-12-20 | 1976-09-22 | Wyeth John & Brother Ltd | Indole derivatives |
| US5283241A (en) * | 1992-08-28 | 1994-02-01 | Merck & Co., Inc. | Benzo-fused lactams promote release of growth hormone |
-
1999
- 1999-08-18 CA CA002340701A patent/CA2340701C/en not_active Expired - Fee Related
- 1999-08-18 KR KR1020017002123A patent/KR100680085B1/ko not_active Expired - Fee Related
- 1999-08-18 CN CNB998098574A patent/CN1161333C/zh not_active Expired - Fee Related
- 1999-08-18 EP EP99938515A patent/EP1105376B1/en not_active Expired - Lifetime
- 1999-08-18 AU AU53011/99A patent/AU5301199A/en not_active Abandoned
- 1999-08-18 AT AT99938515T patent/ATE288895T1/de not_active IP Right Cessation
- 1999-08-18 US US09/763,241 patent/US6576656B1/en not_active Expired - Fee Related
- 1999-08-18 JP JP2000566249A patent/JP4445133B2/ja not_active Expired - Fee Related
- 1999-08-18 ES ES99938515T patent/ES2237135T3/es not_active Expired - Lifetime
- 1999-08-18 WO PCT/JP1999/004443 patent/WO2000010975A1/en not_active Ceased
- 1999-08-18 DE DE69923692T patent/DE69923692T2/de not_active Expired - Lifetime
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