JP2002522462A - 組織外傷に関連した病原プロセスの阻害 - Google Patents
組織外傷に関連した病原プロセスの阻害Info
- Publication number
- JP2002522462A JP2002522462A JP2000564574A JP2000564574A JP2002522462A JP 2002522462 A JP2002522462 A JP 2002522462A JP 2000564574 A JP2000564574 A JP 2000564574A JP 2000564574 A JP2000564574 A JP 2000564574A JP 2002522462 A JP2002522462 A JP 2002522462A
- Authority
- JP
- Japan
- Prior art keywords
- group
- expression
- halofuginone
- collagen
- inhibition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PCT/IL1999/000440 WO2000009070A2 (en) | 1998-08-13 | 1999-08-13 | Inhibition of pathogenic processes related to tissue trauma |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2006504769A (ja) * | 2002-10-31 | 2006-02-09 | ステート オブ イスラエル、ミニストリー オブ アグリカルチャー | 病理学的プロセスに関する遺伝子発現を制御するためのキナゾリノン組成物 |
| WO2012108538A1 (ja) | 2011-02-10 | 2012-08-16 | 国立大学法人 長崎大学 | 急性肺損傷診断方法 |
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| IL143366A0 (en) * | 2001-05-24 | 2002-04-21 | Harasit Medical Res Services & | Treatment of renal fibrosis |
| RU2243778C2 (ru) * | 2003-02-18 | 2005-01-10 | Московский городской научно-исследовательский институт скорой помощи им. Н.В. Склифосовского | Способ лечения последствий травматического и интраоперационного повреждения тканей у больных с политравмой |
| EP2010136B1 (en) * | 2006-04-10 | 2012-09-12 | The President and Fellows of Harvard College | Methods for modulating formation and progression of cellulite |
| EP2114409B1 (en) | 2007-01-21 | 2013-11-20 | Agricultural Research Organization | Composition and method for treating or preventing skeletal muscle fibrosis |
| CN102177152A (zh) | 2008-08-11 | 2011-09-07 | 哈佛大学校长及研究员协会 | 用于抑制tRNA合成酶的卤夫酮(halofuginone)类似物和其用途 |
| US10155742B2 (en) | 2012-01-13 | 2018-12-18 | President And Fellows Of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
| US11708353B2 (en) | 2018-06-08 | 2023-07-25 | The General Hospital Corporation | Inhibitors of prolyl-tRNA-synthetase |
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| DE19951702A1 (de) * | 1999-10-27 | 2001-05-03 | Aventis Pharma Gmbh | Verwendung von 2-Amino-3,4-dihydro-chinazolinen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten |
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- 1999-08-13 CA CA002340176A patent/CA2340176A1/en not_active Abandoned
- 1999-08-13 JP JP2000564574A patent/JP2002522462A/ja active Pending
- 1999-08-13 WO PCT/IL1999/000440 patent/WO2000009070A2/en not_active Ceased
- 1999-08-13 AT AT99936952T patent/ATE307586T1/de not_active IP Right Cessation
- 1999-08-13 AU AU51914/99A patent/AU756437B2/en not_active Ceased
- 1999-08-13 ES ES99936952T patent/ES2255286T3/es not_active Expired - Lifetime
- 1999-08-13 DE DE69927987T patent/DE69927987T2/de not_active Expired - Fee Related
- 1999-08-13 EP EP99936952A patent/EP1109559B1/en not_active Expired - Lifetime
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| US5449678A (en) * | 1994-01-11 | 1995-09-12 | Agricultural Research Organization, Ministry Of Agriculture | Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof |
| WO1996006616A1 (en) * | 1994-08-31 | 1996-03-07 | Davidson, Clifford, M. | Quinazolinone pharmaceuticals and use thereof |
| WO1998000555A1 (en) * | 1996-07-03 | 1998-01-08 | Prockop Darwin J | Recombinant n-proteinase, and the production, methods and uses thereof |
| WO1998003180A2 (en) * | 1996-07-22 | 1998-01-29 | The Victoria University Of Manchester | Use of sex steroids function modulators to treat wounds and fibrotic disorders |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006504769A (ja) * | 2002-10-31 | 2006-02-09 | ステート オブ イスラエル、ミニストリー オブ アグリカルチャー | 病理学的プロセスに関する遺伝子発現を制御するためのキナゾリノン組成物 |
| WO2012108538A1 (ja) | 2011-02-10 | 2012-08-16 | 国立大学法人 長崎大学 | 急性肺損傷診断方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000009070A3 (en) | 2000-10-19 |
| WO2000009070A2 (en) | 2000-02-24 |
| EP1109559B1 (en) | 2005-10-26 |
| EP1109559A2 (en) | 2001-06-27 |
| DE69927987D1 (de) | 2005-12-01 |
| ATE307586T1 (de) | 2005-11-15 |
| ES2255286T3 (es) | 2006-06-16 |
| DE69927987T2 (de) | 2006-11-09 |
| AU756437B2 (en) | 2003-01-16 |
| CA2340176A1 (en) | 2000-02-24 |
| EP1109559A4 (en) | 2002-05-08 |
| AU5191499A (en) | 2000-03-06 |
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