ES2255286T3 - Inhibicion de los procesos patogenicos relacionados con las lesiones del tejido. - Google Patents
Inhibicion de los procesos patogenicos relacionados con las lesiones del tejido.Info
- Publication number
- ES2255286T3 ES2255286T3 ES99936952T ES99936952T ES2255286T3 ES 2255286 T3 ES2255286 T3 ES 2255286T3 ES 99936952 T ES99936952 T ES 99936952T ES 99936952 T ES99936952 T ES 99936952T ES 2255286 T3 ES2255286 T3 ES 2255286T3
- Authority
- ES
- Spain
- Prior art keywords
- halofuginone
- collagen
- expression
- group
- inhibition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL125790 | 1998-08-13 | ||
| IL12579098 | 1998-08-13 | ||
| US13714599P | 1999-06-01 | 1999-06-01 | |
| US137145P | 1999-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2255286T3 true ES2255286T3 (es) | 2006-06-16 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99936952T Expired - Lifetime ES2255286T3 (es) | 1998-08-13 | 1999-08-13 | Inhibicion de los procesos patogenicos relacionados con las lesiones del tejido. |
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| Country | Link |
|---|---|
| EP (1) | EP1109559B1 (enExample) |
| JP (1) | JP2002522462A (enExample) |
| AT (1) | ATE307586T1 (enExample) |
| AU (1) | AU756437B2 (enExample) |
| CA (1) | CA2340176A1 (enExample) |
| DE (1) | DE69927987T2 (enExample) |
| ES (1) | ES2255286T3 (enExample) |
| WO (1) | WO2000009070A2 (enExample) |
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| IL143366A0 (en) * | 2001-05-24 | 2002-04-21 | Harasit Medical Res Services & | Treatment of renal fibrosis |
| EP1558261A4 (en) * | 2002-10-31 | 2008-06-04 | Israel State | CHINAZOLINONE COMPOSITIONS TO REGULATE GENE EXPRESSION IN CONNECTION WITH PATHOLOGICAL PROCESSES |
| RU2243778C2 (ru) * | 2003-02-18 | 2005-01-10 | Московский городской научно-исследовательский институт скорой помощи им. Н.В. Склифосовского | Способ лечения последствий травматического и интраоперационного повреждения тканей у больных с политравмой |
| WO2007120606A2 (en) | 2006-04-10 | 2007-10-25 | President And Fellows Of Harvard College | Methods for modulating formation and progression of cellulite |
| CA2711743C (en) | 2007-01-21 | 2015-04-07 | Agricultural Research Organization | Quinazolinone derivatives for treating or preventing skeletal muscle fibrosis |
| CA2737219C (en) | 2008-08-11 | 2017-02-28 | Tracy Keller | Halofuginone analogs for inhibition of trna synthetases and uses thereof |
| WO2012108538A1 (ja) | 2011-02-10 | 2012-08-16 | 国立大学法人 長崎大学 | 急性肺損傷診断方法 |
| AU2013207796B2 (en) | 2012-01-13 | 2017-04-27 | President And Fellows Of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
| US11708353B2 (en) | 2018-06-08 | 2023-07-25 | The General Hospital Corporation | Inhibitors of prolyl-tRNA-synthetase |
Family Cites Families (12)
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|---|---|---|---|---|
| US3320124A (en) * | 1964-07-20 | 1967-05-16 | American Cyanamid Co | Method for treating coccidiosis with quinazolinones |
| DE2934069A1 (de) * | 1979-08-23 | 1981-03-12 | Hoechst Ag, 6000 Frankfurt | Mittel gegen theileriosen und seine verwendung. |
| JPH08510251A (ja) * | 1993-05-07 | 1996-10-29 | ビー マーゴリン、ソロモン | 線維症の病変の修復と予防のための組成物および方法 |
| CA2113229C (en) * | 1994-01-11 | 1999-04-20 | Mark Pines | Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof |
| IL110831A (en) * | 1994-08-31 | 1998-12-27 | Hadasit Med Res Service | Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis |
| JPH0971586A (ja) * | 1995-09-07 | 1997-03-18 | Yamanouchi Pharmaceut Co Ltd | 新規な二環性縮合イミダゾール誘導体 |
| AU3667397A (en) * | 1996-07-03 | 1998-01-21 | Alain Colige | Recombinant n-proteinase, and the production, methods and uses thereof |
| PT930876E (pt) * | 1996-07-22 | 2005-01-31 | Renovo Ltd | Utilizacao de moduladores da funcao esteroide sexual para tratar feridas e desordens fibroticas |
| EP0941108B1 (en) * | 1996-12-04 | 2002-10-16 | Renovo Limited | Wound healing and treatment of fibrosis |
| US5852024A (en) * | 1997-02-11 | 1998-12-22 | Hadasit | Treatment and prevention of adhesions |
| US6028075A (en) * | 1997-02-11 | 2000-02-22 | Pines; Mark | Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies |
| DE19951702A1 (de) * | 1999-10-27 | 2001-05-03 | Aventis Pharma Gmbh | Verwendung von 2-Amino-3,4-dihydro-chinazolinen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten |
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1999
- 1999-08-13 WO PCT/IL1999/000440 patent/WO2000009070A2/en not_active Ceased
- 1999-08-13 ES ES99936952T patent/ES2255286T3/es not_active Expired - Lifetime
- 1999-08-13 JP JP2000564574A patent/JP2002522462A/ja active Pending
- 1999-08-13 DE DE69927987T patent/DE69927987T2/de not_active Expired - Fee Related
- 1999-08-13 AT AT99936952T patent/ATE307586T1/de not_active IP Right Cessation
- 1999-08-13 AU AU51914/99A patent/AU756437B2/en not_active Ceased
- 1999-08-13 CA CA002340176A patent/CA2340176A1/en not_active Abandoned
- 1999-08-13 EP EP99936952A patent/EP1109559B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU756437B2 (en) | 2003-01-16 |
| ATE307586T1 (de) | 2005-11-15 |
| WO2000009070A3 (en) | 2000-10-19 |
| EP1109559A4 (en) | 2002-05-08 |
| CA2340176A1 (en) | 2000-02-24 |
| EP1109559A2 (en) | 2001-06-27 |
| WO2000009070A2 (en) | 2000-02-24 |
| EP1109559B1 (en) | 2005-10-26 |
| AU5191499A (en) | 2000-03-06 |
| JP2002522462A (ja) | 2002-07-23 |
| DE69927987T2 (de) | 2006-11-09 |
| DE69927987D1 (de) | 2005-12-01 |
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