JP2002522021A5 - - Google Patents
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- Publication number
- JP2002522021A5 JP2002522021A5 JP2000561317A JP2000561317A JP2002522021A5 JP 2002522021 A5 JP2002522021 A5 JP 2002522021A5 JP 2000561317 A JP2000561317 A JP 2000561317A JP 2000561317 A JP2000561317 A JP 2000561317A JP 2002522021 A5 JP2002522021 A5 JP 2002522021A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- polynucleotide
- nucleotide sequence
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 description 100
- 229920001184 polypeptide Polymers 0.000 description 99
- 102000004196 processed proteins & peptides Human genes 0.000 description 99
- 108091033319 polynucleotide Proteins 0.000 description 36
- 102000040430 polynucleotide Human genes 0.000 description 36
- 239000002157 polynucleotide Substances 0.000 description 36
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 33
- 238000000034 method Methods 0.000 description 31
- 239000002773 nucleotide Substances 0.000 description 29
- 125000003729 nucleotide group Chemical group 0.000 description 29
- 210000004027 cell Anatomy 0.000 description 20
- 125000000539 amino acid group Chemical group 0.000 description 17
- 150000007523 nucleic acids Chemical group 0.000 description 11
- 125000003275 alpha amino acid group Chemical group 0.000 description 9
- 239000005557 antagonist Substances 0.000 description 9
- 239000002299 complementary DNA Substances 0.000 description 9
- 102000039446 nucleic acids Human genes 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 7
- 239000000203 mixture Substances 0.000 description 5
- 239000008194 pharmaceutical composition Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000014509 gene expression Effects 0.000 description 4
- 102000014914 Carrier Proteins Human genes 0.000 description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 description 3
- 239000000556 agonist Substances 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 108091008324 binding proteins Proteins 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 238000012217 deletion Methods 0.000 description 2
- 230000037430 deletion Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 238000009396 hybridization Methods 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 229930182817 methionine Natural products 0.000 description 2
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000010188 recombinant method Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 210000003527 eukaryotic cell Anatomy 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 210000003643 myeloid progenitor cell Anatomy 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 210000001236 prokaryotic cell Anatomy 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9364398P | 1998-07-21 | 1998-07-21 | |
| US60/093,643 | 1998-07-21 | ||
| PCT/US1999/016424 WO2000005371A1 (en) | 1998-07-21 | 1999-07-21 | Keratinocyte derived interferon |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002522021A JP2002522021A (ja) | 2002-07-23 |
| JP2002522021A5 true JP2002522021A5 (enExample) | 2006-09-07 |
Family
ID=22240013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000561317A Pending JP2002522021A (ja) | 1998-07-21 | 1999-07-21 | ケラチノサイト由来のインターフェロン |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1100902A4 (enExample) |
| JP (1) | JP2002522021A (enExample) |
| KR (1) | KR100688051B1 (enExample) |
| CN (1) | CN1319137A (enExample) |
| AU (1) | AU765890B2 (enExample) |
| CA (1) | CA2335655A1 (enExample) |
| NZ (1) | NZ509402A (enExample) |
| WO (1) | WO2000005371A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60037978T2 (de) | 1999-12-08 | 2008-05-21 | Amgen Inc., Thousand Oaks | Interferon ähnliche moleküle, und deren verwendungen |
| JP2003529350A (ja) * | 2000-02-15 | 2003-10-07 | キュラジェン コーポレイション | ポリペプチドおよびそれをコードする核酸 |
| EP1605045A3 (en) * | 2000-02-15 | 2006-03-01 | Curagen Corporation | Polypeptides and nucleic acids encoding same |
| KR100975013B1 (ko) * | 2008-02-29 | 2010-08-09 | 김성일 | 원터치로 개폐되는 키홀더 |
| KR200457865Y1 (ko) * | 2009-09-11 | 2012-01-05 | 한국알프스 주식회사 | 자동차용 키 |
| CN108752457B (zh) * | 2018-05-23 | 2019-06-21 | 华中农业大学 | 一种来源于草鱼干扰素的衍生多肽及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
-
1999
- 1999-07-21 EP EP99935752A patent/EP1100902A4/en not_active Withdrawn
- 1999-07-21 AU AU51161/99A patent/AU765890B2/en not_active Ceased
- 1999-07-21 JP JP2000561317A patent/JP2002522021A/ja active Pending
- 1999-07-21 WO PCT/US1999/016424 patent/WO2000005371A1/en not_active Ceased
- 1999-07-21 CN CN99811157A patent/CN1319137A/zh active Pending
- 1999-07-21 KR KR1020017000891A patent/KR100688051B1/ko not_active Expired - Fee Related
- 1999-07-21 CA CA002335655A patent/CA2335655A1/en not_active Abandoned
- 1999-07-21 NZ NZ509402A patent/NZ509402A/en unknown
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