JP2004500037A5 - - Google Patents

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Publication number
JP2004500037A5
JP2004500037A5 JP2001521746A JP2001521746A JP2004500037A5 JP 2004500037 A5 JP2004500037 A5 JP 2004500037A5 JP 2001521746 A JP2001521746 A JP 2001521746A JP 2001521746 A JP2001521746 A JP 2001521746A JP 2004500037 A5 JP2004500037 A5 JP 2004500037A5
Authority
JP
Japan
Prior art keywords
fgf
polypeptide
seq
nucleic acid
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001521746A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004500037A (ja
Filing date
Publication date
Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/en
Priority claimed from PCT/US1999/021090 external-priority patent/WO2000015796A2/en
Priority claimed from PCT/US1999/030999 external-priority patent/WO2001005836A1/en
Priority claimed from PCT/US2000/004414 external-priority patent/WO2001004311A1/en
Application filed filed Critical
Priority claimed from PCT/US2000/006471 external-priority patent/WO2001018210A1/en
Publication of JP2004500037A publication Critical patent/JP2004500037A/ja
Publication of JP2004500037A5 publication Critical patent/JP2004500037A5/ja
Withdrawn legal-status Critical Current

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JP2001521746A 1999-09-08 2000-03-09 繊維芽細胞成長因子−19(fgf−19)核酸及びポリペプチド並びに肥満の治療のための利用の方法 Withdrawn JP2004500037A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/US1999/020594 WO2000015666A2 (en) 1998-09-10 1999-09-08 Compositions and methods for the treatment of tumors
PCT/US1999/021090 WO2000015796A2 (en) 1998-09-16 1999-09-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US1999/030999 WO2001005836A1 (en) 1999-07-20 1999-12-20 Polypeptidic compositions and methods for the treatment of tumors
PCT/US2000/004414 WO2001004311A1 (en) 1999-07-07 2000-02-22 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2000/006471 WO2001018210A1 (en) 1999-09-08 2000-03-09 Fibroblast growth factor-19 (fgf-19) nucleic acids and polypeptides and methods of use for the treatment of obesity

Publications (2)

Publication Number Publication Date
JP2004500037A JP2004500037A (ja) 2004-01-08
JP2004500037A5 true JP2004500037A5 (enExample) 2007-05-10

Family

ID=27485920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001521746A Withdrawn JP2004500037A (ja) 1999-09-08 2000-03-09 繊維芽細胞成長因子−19(fgf−19)核酸及びポリペプチド並びに肥満の治療のための利用の方法

Country Status (7)

Country Link
EP (1) EP1214409B1 (enExample)
JP (1) JP2004500037A (enExample)
CN (1) CN1560249A (enExample)
CA (1) CA2384089A1 (enExample)
DE (1) DE60028054T2 (enExample)
ES (1) ES2264929T3 (enExample)
WO (1) WO2001018210A1 (enExample)

Families Citing this family (31)

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DE60043197D1 (enExample) * 1999-11-18 2009-12-03 Univ Kyoto
US6716626B1 (en) 1999-11-18 2004-04-06 Chiron Corporation Human FGF-21 nucleic acids
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
BRPI0206641B8 (pt) 2001-01-26 2021-05-25 Merck Sharp & Dohme uso de um inibidor da absorção de esteróis
SK288217B6 (sk) 2001-01-26 2014-08-05 Merck Sharp & Dohme Corp. Zmes, terapeutická kombinácia, farmaceutický prostriedok a ich použitie
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
EP1425029A4 (en) 2001-08-10 2006-06-07 Palatin Technologies Inc PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DE60216300T2 (de) 2001-09-21 2007-06-28 Schering Corp. Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
ES2363765T3 (es) * 2002-01-31 2011-08-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Agonistas de fgfr.
US20050119206A1 (en) * 2002-03-14 2005-06-02 Develogen Aktiengesellschaft Fuerentwicklungsbolog Cg8327, cg10823, cg18418, cg15862, cg3768, cg11447 and cg16750 homologous proteins involved in the regulation of energy homeostasis
EP1553912A4 (en) 2002-06-07 2007-08-08 Genentech Inc COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT
AU2003274715A1 (en) * 2002-06-10 2003-12-22 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung L(2)44 dea, wunen-2, grapes, cg2221, cg1172, rutabaga, cg11940, facl involved in the regulation of energy homeostasis
AU2003236557B2 (en) * 2002-06-27 2009-10-01 Verva Pharmaceuticals Pty Ltd Differentiation modulating agents and uses therefor
AU2003268116A1 (en) * 2002-09-18 2004-04-08 Eli Lilly And Company Method for reducing morbidity and mortality in critically ill patients
AU2003291719A1 (en) 2002-11-06 2004-06-03 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US20060153806A1 (en) * 2002-12-16 2006-07-13 Develogen Aktiengesellschaft Fuer Entwicklungsbiol Ogical Forschung Proteins involved in the regulation of energy homeostasis
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CN1756756A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
CA2517573C (en) 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
CA2762955A1 (en) * 2003-10-16 2005-04-28 Imclone Llc Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
TWI388568B (zh) 2006-02-10 2013-03-11 Genentech Inc 抗fgf19抗體及其使用方法
WO2009035786A1 (en) 2007-08-03 2009-03-19 Genentech, Inc. Humanized anti-fgf19 antagonists and methods using same
WO2009046141A2 (en) 2007-10-01 2009-04-09 Isis Pharmaceuticals, Inc. Antisense modulation of fibroblast growth factor receptor 4 expression
CA2839437A1 (en) 2011-06-16 2012-12-20 Isis Pharmaceuticals, Inc. Antisense modulation of fibroblast growth factor receptor 4 expression
TWI670283B (zh) 2013-12-23 2019-09-01 美商建南德克公司 抗體及使用方法
CN113105561B (zh) * 2021-04-30 2021-12-03 江南大学 一种双靶点融合蛋白的制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001516580A (ja) * 1997-09-17 2001-10-02 ジェネンテック・インコーポレーテッド 分泌性の、および膜貫通性のポリぺプチド、およびそれをコードする核酸
AU9312198A (en) * 1997-09-17 1999-04-05 Genentech Inc. Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer
NZ504425A (en) * 1997-11-25 2001-10-26 Genentech Inc Nucleic acid molecules and polypeptides of fibroblast growth factor-19 (PRO533)

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