CN1560249A - 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 - Google Patents

成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 Download PDF

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Publication number
CN1560249A
CN1560249A CNA2004100465359A CN200410046535A CN1560249A CN 1560249 A CN1560249 A CN 1560249A CN A2004100465359 A CNA2004100465359 A CN A2004100465359A CN 200410046535 A CN200410046535 A CN 200410046535A CN 1560249 A CN1560249 A CN 1560249A
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fgf
polypeptide
sequence
antibody
nucleic acid
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CNA2004100465359A
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Chinese (zh)
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蒂莫西・A・斯图尔特
蒂莫西·A·斯图尔特
白・汤姆林森
伊丽莎白·汤姆林森
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Genentech Inc
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Genentech Inc
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Priority claimed from PCT/US1999/020594 external-priority patent/WO2000015666A2/en
Priority claimed from PCT/US1999/021090 external-priority patent/WO2000015796A2/en
Priority claimed from PCT/US1999/030999 external-priority patent/WO2001005836A1/en
Priority claimed from PCT/US2000/004414 external-priority patent/WO2001004311A1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CN1560249A publication Critical patent/CN1560249A/zh
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CNA2004100465359A 1999-09-08 2000-03-09 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法 Pending CN1560249A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
USPCT/US99/20594 1999-09-08
PCT/US1999/020594 WO2000015666A2 (en) 1998-09-10 1999-09-08 Compositions and methods for the treatment of tumors
USPCT/US99/21090 1999-09-15
PCT/US1999/021090 WO2000015796A2 (en) 1998-09-16 1999-09-15 Secreted and transmembrane polypeptides and nucleic acids encoding the same
USPCT/US99/30999 1999-12-20
PCT/US1999/030999 WO2001005836A1 (en) 1999-07-20 1999-12-20 Polypeptidic compositions and methods for the treatment of tumors
USPCT/US00/04414 2000-02-22
PCT/US2000/004414 WO2001004311A1 (en) 1999-07-07 2000-02-22 Secreted and transmembrane polypeptides and nucleic acids encoding the same

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CN00815274A Division CN1387570A (zh) 1999-09-08 2000-03-09 成纤维细胞生长因子－19(fgf－19)的核酸和多肽以及用于治疗肥胖的方法

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CN1560249A true CN1560249A (zh) 2005-01-05

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CNA2004100465359A Pending CN1560249A (zh) 1999-09-08 2000-03-09 成纤维细胞生长因子-19（fgf-19）的核酸和多肽以及用于治疗肥胖的方法

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EP (1) EP1214409B1 (enExample)
JP (1) JP2004500037A (enExample)
CN (1) CN1560249A (enExample)
CA (1) CA2384089A1 (enExample)
DE (1) DE60028054T2 (enExample)
ES (1) ES2264929T3 (enExample)
WO (1) WO2001018210A1 (enExample)

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CN113105561A (zh) * 2021-04-30 2021-07-13 江南大学 一种双靶点融合蛋白的制备方法和应用

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US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
BRPI0206641B8 (pt) 2001-01-26 2021-05-25 Merck Sharp & Dohme uso de um inibidor da absorção de esteróis
SK288217B6 (sk) 2001-01-26 2014-08-05 Merck Sharp & Dohme Corp. Zmes, terapeutická kombinácia, farmaceutický prostriedok a ich použitie
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
EP1425029A4 (en) 2001-08-10 2006-06-07 Palatin Technologies Inc PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DE60216300T2 (de) 2001-09-21 2007-06-28 Schering Corp. Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
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US20050119206A1 (en) * 2002-03-14 2005-06-02 Develogen Aktiengesellschaft Fuerentwicklungsbolog Cg8327, cg10823, cg18418, cg15862, cg3768, cg11447 and cg16750 homologous proteins involved in the regulation of energy homeostasis
EP1553912A4 (en) 2002-06-07 2007-08-08 Genentech Inc COMPOSITIONS AND METHODS FOR TUMOR DIAGNOSIS AND TREATMENT
AU2003274715A1 (en) * 2002-06-10 2003-12-22 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung L(2)44 dea, wunen-2, grapes, cg2221, cg1172, rutabaga, cg11940, facl involved in the regulation of energy homeostasis
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AU2003268116A1 (en) * 2002-09-18 2004-04-08 Eli Lilly And Company Method for reducing morbidity and mortality in critically ill patients
AU2003291719A1 (en) 2002-11-06 2004-06-03 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US20060153806A1 (en) * 2002-12-16 2006-07-13 Develogen Aktiengesellschaft Fuer Entwicklungsbiol Ogical Forschung Proteins involved in the regulation of energy homeostasis
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
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CA2517573C (en) 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
CA2762955A1 (en) * 2003-10-16 2005-04-28 Imclone Llc Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
TWI388568B (zh) 2006-02-10 2013-03-11 Genentech Inc 抗ｆｇｆ１９抗體及其使用方法
WO2009035786A1 (en) 2007-08-03 2009-03-19 Genentech, Inc. Humanized anti-fgf19 antagonists and methods using same
WO2009046141A2 (en) 2007-10-01 2009-04-09 Isis Pharmaceuticals, Inc. Antisense modulation of fibroblast growth factor receptor 4 expression
CA2839437A1 (en) 2011-06-16 2012-12-20 Isis Pharmaceuticals, Inc. Antisense modulation of fibroblast growth factor receptor 4 expression
TWI670283B (zh) 2013-12-23 2019-09-01 美商建南德克公司 抗體及使用方法

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JP2001516580A (ja) * 1997-09-17 2001-10-02 ジェネンテック・インコーポレーテッド 分泌性の、および膜貫通性のポリぺプチド、およびそれをコードする核酸
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113105561A (zh) * 2021-04-30 2021-07-13 江南大学 一种双靶点融合蛋白的制备方法和应用
US11845781B2 (en) 2021-04-30 2023-12-19 Jiangnan University Fusion protein comprising fibroblast growth factor 19 (FGF 19) and glucagon-like peptide-1

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DE60028054D1 (de) 2006-06-22
WO2001018210A1 (en) 2001-03-15
DE60028054T2 (de) 2006-12-21
JP2004500037A (ja) 2004-01-08
EP1214409A1 (en) 2002-06-19
EP1214409B1 (en) 2006-05-17
ES2264929T3 (es) 2007-02-01

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