JP2002516325A - 新規な置換イミダゾール化合物 - Google Patents
新規な置換イミダゾール化合物Info
- Publication number
- JP2002516325A JP2002516325A JP2000550846A JP2000550846A JP2002516325A JP 2002516325 A JP2002516325 A JP 2002516325A JP 2000550846 A JP2000550846 A JP 2000550846A JP 2000550846 A JP2000550846 A JP 2000550846A JP 2002516325 A JP2002516325 A JP 2002516325A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heterocyclic
- hydrogen
- aryl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8664598P | 1998-05-26 | 1998-05-26 | |
| US60/086,645 | 1998-05-26 | ||
| PCT/US1999/011455 WO1999061440A1 (fr) | 1998-05-26 | 1999-05-25 | Nouveaux composes d'imidazole substitue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002516325A true JP2002516325A (ja) | 2002-06-04 |
Family
ID=22199934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000550846A Withdrawn JP2002516325A (ja) | 1998-05-26 | 1999-05-25 | 新規な置換イミダゾール化合物 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1082320A4 (fr) |
| JP (1) | JP2002516325A (fr) |
| CA (1) | CA2333157A1 (fr) |
| WO (1) | WO1999061440A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004075915A1 (fr) * | 2003-02-26 | 2004-09-10 | Kowa Co. Ltd. | Traitement de la dermatite de contact allergique |
| JP2012522762A (ja) * | 2009-04-01 | 2012-09-27 | ザ メディカル リサーチ， インフラストラクチャー， アンド ヘルス サーヴィシーズ ファンド オブ ザ テル アヴィヴ メディカル センター | ケラチノサイトの増殖および分化を調節する方法 |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998056377A1 (fr) | 1997-06-13 | 1998-12-17 | Smithkline Beecham Corporation | Nouveaux composes de pyrazole et de pyrazoline substitues |
| US6610695B1 (en) | 1997-06-19 | 2003-08-26 | Smithkline Beecham Corporation | Aryloxy substituted pyrimidine imidazole compounds |
| US6489325B1 (en) | 1998-07-01 | 2002-12-03 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| US6562832B1 (en) | 1997-07-02 | 2003-05-13 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| JP2001518507A (ja) | 1997-10-08 | 2001-10-16 | スミスクライン・ビーチャム・コーポレイション | 新規シクロアルケニル置換化合物 |
| CA2341370A1 (fr) | 1998-08-20 | 2000-03-02 | Smithkline Beecham Corporation | Nouveaux composes de triazole substitues |
| WO2000035436A2 (fr) * | 1998-12-16 | 2000-06-22 | Warner-Lambert Company | Traitement de l'arthrite a l'aide d'inhibiteurs de la mek |
| JP2003514899A (ja) | 1999-11-23 | 2003-04-22 | スミスクライン・ビーチャム・コーポレイション | ＣＳＢＰ／ｐ３８キナーゼ阻害剤としての３，４‐ジヒドロ−（１Ｈ）−キナゾリン−２−オン化合物 |
| US6495582B1 (en) * | 2000-09-15 | 2002-12-17 | Vertex Pharmaceuticals Incorporated | Isoxazole compositions useful as inhibitors of ERK |
| EE200300437A (et) | 2001-03-09 | 2004-02-16 | Pfizer Products Inc. | Triasolopüridiinid kui põletikuvastased ained |
| DE60207390T2 (de) | 2001-03-09 | 2006-07-20 | Pfizer Products Inc., Groton | Entzündungshemmende benzimidazolverbindungen |
| ES2247271T3 (es) | 2001-04-04 | 2006-03-01 | Pfizer Products Inc. | Nuevos benzotriazoles como compuestos antiinflamatorios. |
| WO2004004725A2 (fr) | 2002-07-09 | 2004-01-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Nouvelles compositions pharmaceutiques a base de nouveaux anticholinergiques et d'inhibiteurs de la kinase p38 |
| EP1539121A4 (fr) * | 2002-08-29 | 2008-08-13 | Scios Inc | Methode pour favoriser l'osteogenese |
| US7012143B2 (en) | 2002-08-30 | 2006-03-14 | Dombroski Mark A | Cycloalkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines |
| US6949652B2 (en) | 2002-08-30 | 2005-09-27 | Pfizer, Inc. | Crystalline forms of 3-isopropyl-6-[4-(2,5-difluoro-phenyl)-oxazol-5-yl]-[1,2,4]triazolo-[4,3-A]pyridine |
| PA8579601A1 (es) | 2002-08-30 | 2004-05-07 | Pfizer Prod Inc | Compuestos antiinflamatorios de di y trifloruro-triazolo-piridinas |
| US7037923B2 (en) | 2002-08-30 | 2006-05-02 | Pfizer, Inc. | Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines |
| US7005523B2 (en) | 2002-08-30 | 2006-02-28 | Pfizer Inc. | Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines |
| US7244441B2 (en) | 2003-09-25 | 2007-07-17 | Scios, Inc. | Stents and intra-luminal prostheses containing map kinase inhibitors |
| US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
| WO2006050249A1 (fr) * | 2004-10-29 | 2006-05-11 | Vertex Pharmaceuticals Incorporated | Derives de diaminotriazole utilises comme inhibiteurs de proteine kinases |
| PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
| EP1676574A3 (fr) | 2004-12-30 | 2006-07-26 | Johnson & Johnson Vision Care, Inc. | Procédé favorisant la survie des tissus ou cellules griffées |
| EP1992344A1 (fr) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 alpha comme cible therapeutique pour les maladies associées á une mutation de FGFR3 |
| EP2350274B1 (fr) | 2008-10-21 | 2019-01-23 | The General Hospital Corporation | Transplantation de cellules |
| CN108504539B (zh) | 2010-08-06 | 2021-11-02 | 通用医院公司以麻省总医院名义经营 | 用于细胞处理相关应用的系统和设备 |
| CN113518779B (zh) | 2019-03-28 | 2024-03-15 | 江苏恒瑞医药股份有限公司 | 噻吩并杂环类衍生物、其制备方法及其在医药上的应用 |
| AU2020251621A1 (en) | 2019-03-29 | 2021-11-04 | Jiangsu Hengrui Medicine Co., Ltd. | Pyrroloheterocyclic derivative, preparation method therefor, and application thereof in medicine |
| US20220204512A1 (en) | 2019-05-24 | 2022-06-30 | Jiangsu Hengrui Medicine Co., Ltd. | Substituted fused bicyclic derivative, preparation method therefor, and application thereof in medicines |
| CN116437915A (zh) | 2020-09-29 | 2023-07-14 | 江苏恒瑞医药股份有限公司 | 一种吡咯并杂环类衍生物的晶型及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
| AU5147598A (en) * | 1996-10-17 | 1998-05-11 | Smithkline Beecham Corporation | Methods for reversibly inhibiting myelopoiesis in mammalian tissue |
-
1999
- 1999-05-25 CA CA002333157A patent/CA2333157A1/fr not_active Abandoned
- 1999-05-25 JP JP2000550846A patent/JP2002516325A/ja not_active Withdrawn
- 1999-05-25 EP EP99924480A patent/EP1082320A4/fr not_active Withdrawn
- 1999-05-25 WO PCT/US1999/011455 patent/WO1999061440A1/fr not_active Application Discontinuation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004075915A1 (fr) * | 2003-02-26 | 2004-09-10 | Kowa Co. Ltd. | Traitement de la dermatite de contact allergique |
| JPWO2004075915A1 (ja) * | 2003-02-26 | 2006-06-01 | 興和株式会社 | アレルギー性接触性皮膚炎治療薬 |
| JP2012522762A (ja) * | 2009-04-01 | 2012-09-27 | ザ メディカル リサーチ， インフラストラクチャー， アンド ヘルス サーヴィシーズ ファンド オブ ザ テル アヴィヴ メディカル センター | ケラチノサイトの増殖および分化を調節する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999061440A1 (fr) | 1999-12-02 |
| CA2333157A1 (fr) | 1999-12-02 |
| EP1082320A1 (fr) | 2001-03-14 |
| EP1082320A4 (fr) | 2001-11-21 |
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