JP2002508656A - 抗−アルファベータ３ヒト化モノクローナル抗体 - Google Patents
抗−アルファベータ３ヒト化モノクローナル抗体Info
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- JP2002508656A JP2002508656A JP53986098A JP53986098A JP2002508656A JP 2002508656 A JP2002508656 A JP 2002508656A JP 53986098 A JP53986098 A JP 53986098A JP 53986098 A JP53986098 A JP 53986098A JP 2002508656 A JP2002508656 A JP 2002508656A
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3960997P | 1997-03-12 | 1997-03-12 | |
| US60/039,609 | 1997-03-12 | ||
| PCT/US1998/004987 WO1998040488A1 (en) | 1997-03-12 | 1998-03-12 | Anti-alphabeta3 humanized monoclonal antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002508656A true JP2002508656A (ja) | 2002-03-19 |
| JP2002508656A5 JP2002508656A5 (enExample) | 2005-11-10 |
Family
ID=21906403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53986098A Pending JP2002508656A (ja) | 1997-03-12 | 1998-03-12 | 抗−アルファベータ３ヒト化モノクローナル抗体 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7230083B2 (enExample) |
| EP (2) | EP0968290B1 (enExample) |
| JP (1) | JP2002508656A (enExample) |
| AU (1) | AU6702998A (enExample) |
| CA (1) | CA2284518A1 (enExample) |
| DE (1) | DE69828154T2 (enExample) |
| ES (1) | ES2234099T3 (enExample) |
| WO (1) | WO1998040488A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023523016A (ja) * | 2020-04-23 | 2023-06-01 | アルファ・ベータ・ホールディングス，リミテッド・ライアビリティ・カンパニー | がんを処置するための組成物および方法 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002508656A (ja) * | 1997-03-12 | 2002-03-19 | スミスクライン・ビーチャム・コーポレイション | 抗−アルファベータ３ヒト化モノクローナル抗体 |
| GB9823071D0 (en) * | 1998-10-21 | 1998-12-16 | Affibody Technology Ab | A method |
| US6160099A (en) * | 1998-11-24 | 2000-12-12 | Jonak; Zdenka Ludmila | Anti-human αv β3 and αv β5 antibodies |
| US7306925B2 (en) | 2001-11-09 | 2007-12-11 | Vanderbilt University | Phage antibodies to radiation-inducible neoantigens |
| US7906102B2 (en) | 2001-10-03 | 2011-03-15 | Vanderbilt University | Ligands to radiation-induced molecules |
| AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| US7674884B2 (en) * | 2003-12-10 | 2010-03-09 | Novimmune S.A. | Neutralizing antibodies and methods of use thereof |
| US7351739B2 (en) | 2004-04-30 | 2008-04-01 | Wellgen, Inc. | Bioactive compounds and methods of uses thereof |
| DE102004059357B8 (de) * | 2004-12-03 | 2009-12-03 | Universität Leipzig | Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung |
| CA2611519A1 (en) | 2005-06-17 | 2006-12-28 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
| WO2008094176A2 (en) * | 2006-06-19 | 2008-08-07 | Tolerx, Inc. | Ilt3 binding molecules and uses therefor |
| AU2007272970C1 (en) | 2006-07-11 | 2013-01-10 | Roy C. Levitt | Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors |
| CA2660519A1 (en) | 2006-08-10 | 2008-02-21 | Roy C. Levitt | Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors |
| WO2010002862A2 (en) * | 2008-07-01 | 2010-01-07 | Aveo Pharmaceuticals, Inc. | Fibroblast growth factor receptor 3 (fgfr3) binding proteins |
| WO2013019730A1 (en) | 2011-07-29 | 2013-02-07 | The Washington University | Antibodies to tip-1 and grp78 |
| US10449261B2 (en) | 2014-07-24 | 2019-10-22 | Washington University | Compositions targeting radiation-induced molecules and methods of use thereof |
| WO2018148595A1 (en) | 2017-02-10 | 2018-08-16 | Washington University | Antibodies to tip1 and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2807189A (en) * | 1987-11-19 | 1989-07-05 | Scripps Clinic And Research Foundation | Monoclonal antibody against the rgd-directed adhesion receptor of endothelial cells |
| DE69322860T2 (de) * | 1992-04-03 | 1999-07-01 | Genentech, Inc., South San Francisco, Calif. | Antikörper gegen alpha v beta 3 integrin |
| AU679626B2 (en) * | 1994-03-08 | 1997-07-03 | Wyeth | Thiazolidinedione derivatives as anti-hyperglycemic agents |
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| JP2002508656A (ja) * | 1997-03-12 | 2002-03-19 | スミスクライン・ビーチャム・コーポレイション | 抗−アルファベータ３ヒト化モノクローナル抗体 |
| US6160099A (en) * | 1998-11-24 | 2000-12-12 | Jonak; Zdenka Ludmila | Anti-human αv β3 and αv β5 antibodies |
-
1998
- 1998-03-12 JP JP53986098A patent/JP2002508656A/ja active Pending
- 1998-03-12 WO PCT/US1998/004987 patent/WO1998040488A1/en not_active Ceased
- 1998-03-12 ES ES98909183T patent/ES2234099T3/es not_active Expired - Lifetime
- 1998-03-12 AU AU67029/98A patent/AU6702998A/en not_active Abandoned
- 1998-03-12 EP EP98909183A patent/EP0968290B1/en not_active Expired - Lifetime
- 1998-03-12 DE DE69828154T patent/DE69828154T2/de not_active Expired - Fee Related
- 1998-03-12 EP EP04077315A patent/EP1491632A3/en not_active Withdrawn
- 1998-03-12 CA CA002284518A patent/CA2284518A1/en not_active Abandoned
-
2002
- 2002-08-20 US US10/223,880 patent/US7230083B2/en not_active Expired - Fee Related
-
2006
- 2006-10-18 US US11/582,745 patent/US7504102B2/en not_active Expired - Fee Related
-
2007
- 2007-04-25 US US11/739,755 patent/US20080160576A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023523016A (ja) * | 2020-04-23 | 2023-06-01 | アルファ・ベータ・ホールディングス，リミテッド・ライアビリティ・カンパニー | がんを処置するための組成物および方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7230083B2 (en) | 2007-06-12 |
| AU6702998A (en) | 1998-09-29 |
| US20080160576A1 (en) | 2008-07-03 |
| DE69828154T2 (de) | 2005-06-23 |
| EP1491632A3 (en) | 2006-01-04 |
| DE69828154D1 (de) | 2005-01-20 |
| US7504102B2 (en) | 2009-03-17 |
| CA2284518A1 (en) | 1998-09-17 |
| EP0968290B1 (en) | 2004-12-15 |
| US20070053902A1 (en) | 2007-03-08 |
| WO1998040488A1 (en) | 1998-09-17 |
| US20030152571A1 (en) | 2003-08-14 |
| EP0968290A1 (en) | 2000-01-05 |
| ES2234099T3 (es) | 2005-06-16 |
| EP1491632A2 (en) | 2004-12-29 |
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