DE102004059357B8 - Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung - Google Patents
Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung Download PDFInfo
- Publication number
- DE102004059357B8 DE102004059357B8 DE102004059357A DE102004059357A DE102004059357B8 DE 102004059357 B8 DE102004059357 B8 DE 102004059357B8 DE 102004059357 A DE102004059357 A DE 102004059357A DE 102004059357 A DE102004059357 A DE 102004059357A DE 102004059357 B8 DE102004059357 B8 DE 102004059357B8
- Authority
- DE
- Germany
- Prior art keywords
- ligands
- interaction
- antibody blocking
- human thy
- thy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004059357A DE102004059357B8 (de) | 2004-12-03 | 2004-12-03 | Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004059357A DE102004059357B8 (de) | 2004-12-03 | 2004-12-03 | Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung |
Publications (3)
Publication Number | Publication Date |
---|---|
DE102004059357A1 DE102004059357A1 (de) | 2006-06-14 |
DE102004059357B4 DE102004059357B4 (de) | 2009-02-12 |
DE102004059357B8 true DE102004059357B8 (de) | 2009-12-03 |
Family
ID=36500169
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE102004059357A Expired - Fee Related DE102004059357B8 (de) | 2004-12-03 | 2004-12-03 | Antikörper, welcher die Interaktion von humanem Thy-1 und dessen Liganden blockiert, sowie dessen Verwendung |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE102004059357B8 (de) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69315847T2 (de) * | 1992-08-21 | 1998-06-25 | Genentech Inc | Verfahren zur behandlung einer durch lfa-1 vermittelten störung |
DE19944995C1 (de) * | 1999-07-29 | 2000-12-21 | Gsf Forschungszentrum Umwelt | Nachweis einer irreversiblen Schädigung von IgG Antikörpern |
DE10242337A1 (de) * | 2002-09-09 | 2004-03-18 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antikörper zur Isolierung und/oder Identifizierung neuronaler Stammzellen und Verfahren zur Isolierung und/oder Identifizierung neuronaler Vorläuferzellen |
DE69828154T2 (de) * | 1997-03-12 | 2005-06-23 | Smithkline Beecham Corp. | Anti-alphavbeta3 humanizierte monoklonale antikörper |
-
2004
- 2004-12-03 DE DE102004059357A patent/DE102004059357B8/de not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69315847T2 (de) * | 1992-08-21 | 1998-06-25 | Genentech Inc | Verfahren zur behandlung einer durch lfa-1 vermittelten störung |
DE69828154T2 (de) * | 1997-03-12 | 2005-06-23 | Smithkline Beecham Corp. | Anti-alphavbeta3 humanizierte monoklonale antikörper |
DE19944995C1 (de) * | 1999-07-29 | 2000-12-21 | Gsf Forschungszentrum Umwelt | Nachweis einer irreversiblen Schädigung von IgG Antikörpern |
DE10242337A1 (de) * | 2002-09-09 | 2004-03-18 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antikörper zur Isolierung und/oder Identifizierung neuronaler Stammzellen und Verfahren zur Isolierung und/oder Identifizierung neuronaler Vorläuferzellen |
Non-Patent Citations (6)
Title |
---|
Anne Wetzel et al.,"Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)", Journal of Immunology (15. März 2004), Vol. 172, 3850-3859 * |
CA AN 125:139735 * |
Forschungsbericht der Univ. Leipzig 1999, Dr. Saalbach * |
Forschungsbericht der Univ. Leipzig 2003, Dr. Saalbach * |
Medline Abstr. AN 96021265 * |
Medline Abstr. AN 96021265 CA AN 125:139735 Forschungsbericht der Univ. Leipzig 1999, Dr. Saalbach Forschungsbericht der Univ. Leipzig 2003, Dr. Saalbach Anne Wetzel et al.,"Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)", Journal of Immunology (15. März 2004), Vol. 172, 3850-3859 |
Also Published As
Publication number | Publication date |
---|---|
DE102004059357A1 (de) | 2006-06-14 |
DE102004059357B4 (de) | 2009-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
OP8 | Request for examination as to paragraph 44 patent law | ||
8364 | No opposition during term of opposition | ||
8381 | Inventor (new situation) |
Inventor name: WETZEL, ANNE, DIPL.-BIOL., 04299 LEIPZIG, DE Inventor name: ANDEREGG, ULF, DR.RER.NAT.HABIL., 04416 MARKKL, DE Inventor name: SAALBACH, ANJA, DR.RER.NAT.HABIL., 04435 SCHKE, DE |
|
8396 | Reprint of erroneous front page | ||
R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Effective date: 20130702 |