JP2002500020A - 嫌気性細菌の毒性化合物による阻止および殺害を迅速に評価する方法 - Google Patents
嫌気性細菌の毒性化合物による阻止および殺害を迅速に評価する方法Info
- Publication number
- JP2002500020A JP2002500020A JP2000526667A JP2000526667A JP2002500020A JP 2002500020 A JP2002500020 A JP 2002500020A JP 2000526667 A JP2000526667 A JP 2000526667A JP 2000526667 A JP2000526667 A JP 2000526667A JP 2002500020 A JP2002500020 A JP 2002500020A
- Authority
- JP
- Japan
- Prior art keywords
- water
- dye
- nutrient
- treated
- biocide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 92
- 230000002147 killing effect Effects 0.000 title description 6
- 241001148471 unidentified anaerobic bacterium Species 0.000 title description 5
- 231100000167 toxic agent Toxicity 0.000 title description 4
- 230000005764 inhibitory process Effects 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 58
- 239000004599 antimicrobial Substances 0.000 claims abstract description 39
- 230000002401 inhibitory effect Effects 0.000 claims abstract description 21
- 239000007793 ph indicator Substances 0.000 claims abstract description 18
- 239000004215 Carbon black (E152) Substances 0.000 claims abstract description 13
- 229930195733 hydrocarbon Natural products 0.000 claims abstract description 13
- 150000002430 hydrocarbons Chemical class 0.000 claims abstract description 13
- 230000007613 environmental effect Effects 0.000 claims abstract description 10
- 235000015097 nutrients Nutrition 0.000 claims description 57
- 230000008859 change Effects 0.000 claims description 34
- 239000000203 mixture Substances 0.000 claims description 22
- 239000000126 substance Substances 0.000 claims description 18
- 238000013207 serial dilution Methods 0.000 claims description 14
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 10
- 239000002207 metabolite Substances 0.000 claims description 10
- 235000013336 milk Nutrition 0.000 claims description 10
- 239000008267 milk Substances 0.000 claims description 10
- 210000004080 milk Anatomy 0.000 claims description 10
- 239000000498 cooling water Substances 0.000 claims description 8
- 239000008103 glucose Substances 0.000 claims description 7
- 238000004448 titration Methods 0.000 claims description 7
- 239000011261 inert gas Substances 0.000 claims description 6
- 239000001888 Peptone Substances 0.000 claims description 5
- 108010080698 Peptones Proteins 0.000 claims description 5
- 235000015278 beef Nutrition 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
- 235000019319 peptone Nutrition 0.000 claims description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
- WWAABJGNHFGXSJ-UHFFFAOYSA-N chlorophenol red Chemical compound C1=C(Cl)C(O)=CC=C1C1(C=2C=C(Cl)C(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 WWAABJGNHFGXSJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000005715 Fructose Substances 0.000 claims description 3
- 229930091371 Fructose Natural products 0.000 claims description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 3
- 229940041514 candida albicans extract Drugs 0.000 claims description 3
- 238000012258 culturing Methods 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 239000012137 tryptone Substances 0.000 claims description 3
- 239000002351 wastewater Substances 0.000 claims description 3
- 239000012138 yeast extract Substances 0.000 claims description 3
- ZPLCXHWYPWVJDL-UHFFFAOYSA-N 4-[(4-hydroxyphenyl)methyl]-1,3-oxazolidin-2-one Chemical compound C1=CC(O)=CC=C1CC1NC(=O)OC1 ZPLCXHWYPWVJDL-UHFFFAOYSA-N 0.000 claims description 2
- FRPHFZCDPYBUAU-UHFFFAOYSA-N Bromocresolgreen Chemical compound CC1=C(Br)C(O)=C(Br)C=C1C1(C=2C(=C(Br)C(O)=C(Br)C=2)C)C2=CC=CC=C2S(=O)(=O)O1 FRPHFZCDPYBUAU-UHFFFAOYSA-N 0.000 claims description 2
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 claims description 2
- 229910002091 carbon monoxide Inorganic materials 0.000 claims description 2
- 230000003111 delayed effect Effects 0.000 claims description 2
- XJRPTMORGOIMMI-UHFFFAOYSA-N ethyl 2-amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate Chemical compound CCOC(=O)C=1SC(N)=NC=1C(F)(F)F XJRPTMORGOIMMI-UHFFFAOYSA-N 0.000 claims description 2
- 235000011187 glycerol Nutrition 0.000 claims description 2
- CEQFOVLGLXCDCX-WUKNDPDISA-N methyl red Chemical compound C1=CC(N(C)C)=CC=C1\N=N\C1=CC=CC=C1C(O)=O CEQFOVLGLXCDCX-WUKNDPDISA-N 0.000 claims description 2
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical compound [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 claims description 2
- 239000003208 petroleum Substances 0.000 claims description 2
- 229960003531 phenolsulfonphthalein Drugs 0.000 claims description 2
- 230000003134 recirculating effect Effects 0.000 claims description 2
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003139 biocide Substances 0.000 abstract description 77
- 230000003115 biocidal effect Effects 0.000 abstract description 53
- 244000005700 microbiome Species 0.000 abstract description 26
- 230000000845 anti-microbial effect Effects 0.000 abstract description 17
- 238000010998 test method Methods 0.000 abstract description 13
- 230000004060 metabolic process Effects 0.000 abstract description 10
- 239000006227 byproduct Substances 0.000 abstract description 7
- 230000015572 biosynthetic process Effects 0.000 abstract description 3
- 239000000523 sample Substances 0.000 description 52
- 239000000975 dye Substances 0.000 description 48
- 238000012360 testing method Methods 0.000 description 36
- 230000000813 microbial effect Effects 0.000 description 32
- 239000008235 industrial water Substances 0.000 description 17
- 230000003641 microbiacidal effect Effects 0.000 description 15
- 239000000243 solution Substances 0.000 description 15
- 241000894006 Bacteria Species 0.000 description 14
- 239000007788 liquid Substances 0.000 description 14
- 229940124561 microbicide Drugs 0.000 description 13
- 230000000694 effects Effects 0.000 description 10
- 238000007792 addition Methods 0.000 description 9
- 230000001580 bacterial effect Effects 0.000 description 8
- 239000002609 medium Substances 0.000 description 8
- 238000005260 corrosion Methods 0.000 description 7
- 230000007797 corrosion Effects 0.000 description 7
- 239000001963 growth medium Substances 0.000 description 7
- 230000001954 sterilising effect Effects 0.000 description 7
- 238000004659 sterilization and disinfection Methods 0.000 description 7
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- 239000002855 microbicide agent Substances 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 229920001817 Agar Polymers 0.000 description 5
- 235000010419 agar Nutrition 0.000 description 5
- 239000008272 agar Substances 0.000 description 4
- 239000012736 aqueous medium Substances 0.000 description 4
- 238000001479 atomic absorption spectroscopy Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002824 redox indicator Substances 0.000 description 4
- 239000002455 scale inhibitor Substances 0.000 description 4
- 238000012216 screening Methods 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000001569 carbon dioxide Substances 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- 239000008121 dextrose Substances 0.000 description 3
- 230000008030 elimination Effects 0.000 description 3
- 238000003379 elimination reaction Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000003623 enhancer Substances 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000037323 metabolic rate Effects 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000000700 radioactive tracer Substances 0.000 description 3
- 230000004044 response Effects 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- GUUULVAMQJLDSY-UHFFFAOYSA-N 4,5-dihydro-1,2-thiazole Chemical compound C1CC=NS1 GUUULVAMQJLDSY-UHFFFAOYSA-N 0.000 description 2
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- PLXBWHJQWKZRKG-UHFFFAOYSA-N Resazurin Chemical compound C1=CC(=O)C=C2OC3=CC(O)=CC=C3[N+]([O-])=C21 PLXBWHJQWKZRKG-UHFFFAOYSA-N 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 230000007269 microbial metabolism Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 238000010561 standard procedure Methods 0.000 description 2
- 238000012414 sterilization procedure Methods 0.000 description 2
- 239000012085 test solution Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- 241001112696 Clostridia Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 241000283070 Equus zebra Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000206672 Gelidium Species 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241000372132 Hydrometridae Species 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
- 230000004099 anaerobic respiration Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 1
- 230000003833 cell viability Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000010779 crude oil Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000005558 fluorometry Methods 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- JORABGDXCIBAFL-UHFFFAOYSA-M iodonitrotetrazolium chloride Chemical compound [Cl-].C1=CC([N+](=O)[O-])=CC=C1N1[N+](C=2C=CC(I)=CC=2)=NC(C=2C=CC=CC=2)=N1 JORABGDXCIBAFL-UHFFFAOYSA-M 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000020191 long-life milk Nutrition 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 1
- JWZXKXIUSSIAMR-UHFFFAOYSA-N methylene bis(thiocyanate) Chemical class N#CSCSC#N JWZXKXIUSSIAMR-UHFFFAOYSA-N 0.000 description 1
- 235000021243 milk fat Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 239000003128 rodenticide Substances 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
- 238000001429 visible spectrum Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 238000007704 wet chemistry method Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/22—Testing for sterility conditions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99514497A | 1997-12-29 | 1997-12-29 | |
US08/995,144 | 1997-12-29 | ||
PCT/US1998/025864 WO1999034013A1 (en) | 1997-12-29 | 1998-12-04 | A rapid method for the assessment of the inhibition and kill of anaerobic bacteria by toxic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002500020A true JP2002500020A (ja) | 2002-01-08 |
Family
ID=25541452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000526667A Pending JP2002500020A (ja) | 1997-12-29 | 1998-12-04 | 嫌気性細菌の毒性化合物による阻止および殺害を迅速に評価する方法 |
Country Status (10)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010539903A (ja) * | 2007-09-20 | 2010-12-24 | ダウ グローバル テクノロジーズ インコーポレイティド | 殺生物剤の嫌気性微生物に対する評価のための高処理量の試験方法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002054865A1 (fr) * | 2001-01-09 | 2002-07-18 | Kurita Water Industries Ltd. | Procede de selection d'un agent antimicrobien et procede d'utilisation de ce dernier |
EP1639122B1 (en) | 2003-07-02 | 2009-02-11 | DSM IP Assets B.V. | Improved test system for the determination of the presence of an antibiotic in a fluid |
CA2735467C (en) * | 2008-08-27 | 2017-05-09 | Stepan Company | Potentiated biocidal compositions including quaternary ammonium compound and methods of use |
CN105087361A (zh) * | 2015-09-08 | 2015-11-25 | 湖州一控医疗科技有限公司 | 一种悬液式生物指示剂及其制备方法 |
US11071301B2 (en) | 2016-10-21 | 2021-07-27 | Ecolab Usa Inc. | Anti-microbial agent to control biomass accumulation in SO2 scrubbers |
EP4288518B1 (de) * | 2021-02-08 | 2025-03-05 | C-Square Bioscience GmbH | Vorrichtung und verfahren zum regeln eines mikroorganismen-gehalts |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5094955A (en) * | 1988-03-15 | 1992-03-10 | Akzo N.V. | Device and method for detecting microorganisms |
US5252484A (en) * | 1988-11-29 | 1993-10-12 | Minnesota Mining And Manufacturing Company | Rapid read-out biological indicator |
US5206151A (en) * | 1990-06-11 | 1993-04-27 | Nalco Chemical Company | Rapid selection of biocide using a reduction oxidation indicator system |
CA2058252A1 (en) * | 1991-03-18 | 1992-09-19 | Linda R. Robertson | Synergistic product selection test for biocides |
US5885791A (en) * | 1995-11-16 | 1999-03-23 | The Research And Development Institute, Inc. | Antifungal and antibacterial susceptibility assay |
-
1998
- 1998-12-04 CN CN98813419A patent/CN1284135A/zh active Pending
- 1998-12-04 ID IDW20001264A patent/ID26631A/id unknown
- 1998-12-04 WO PCT/US1998/025864 patent/WO1999034013A1/en not_active Application Discontinuation
- 1998-12-04 NZ NZ505399A patent/NZ505399A/xx unknown
- 1998-12-04 KR KR1020007007249A patent/KR20010033726A/ko not_active Withdrawn
- 1998-12-04 EP EP98960774A patent/EP1051510A4/en not_active Withdrawn
- 1998-12-04 JP JP2000526667A patent/JP2002500020A/ja active Pending
- 1998-12-04 AU AU16292/99A patent/AU1629299A/en not_active Abandoned
- 1998-12-04 CA CA002316806A patent/CA2316806A1/en not_active Abandoned
- 1998-12-07 IN IN2139CA1998 patent/IN185760B/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010539903A (ja) * | 2007-09-20 | 2010-12-24 | ダウ グローバル テクノロジーズ インコーポレイティド | 殺生物剤の嫌気性微生物に対する評価のための高処理量の試験方法 |
Also Published As
Publication number | Publication date |
---|---|
KR20010033726A (ko) | 2001-04-25 |
WO1999034013A1 (en) | 1999-07-08 |
AU1629299A (en) | 1999-07-19 |
IN185760B (enrdf_load_stackoverflow) | 2001-04-21 |
EP1051510A1 (en) | 2000-11-15 |
CN1284135A (zh) | 2001-02-14 |
NZ505399A (en) | 2002-10-25 |
ID26631A (id) | 2001-01-25 |
CA2316806A1 (en) | 1999-07-08 |
EP1051510A4 (en) | 2003-01-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3855762T2 (de) | Direkte Methode zum Nachweis von sehr niedrigerem Grad der Coliform-Kontamination | |
Sherr et al. | Estimating abundance and single-cell characteristics of respiring bacteria via the redox dye CTC | |
Edberg et al. | A defined substrate technology for the enumeration of microbial indicators of environmental pollution | |
DE69214931T2 (de) | Verfahren und Kit zum Nachweis von mikrobiellem Metabolismus | |
US6046021A (en) | Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a multiwell testing device | |
DE69815038T2 (de) | Universales testsystem und verfahren zu seiner verwendung zur identifizierung diverse familien von mikroorganismen | |
DE69531007T2 (de) | Medium zum nachweis von enterococci in einer probe | |
JP5554711B2 (ja) | 殺生物剤の嫌気性微生物に対する評価のための高処理量の試験方法 | |
DE69018567T2 (de) | Verfahren zum Nachweis von Mikroorganismen durch Verwendung von Resorufin oder Orcirufin. | |
DE2841896C3 (de) | Verfahren zum Nachweis einer toxischen Substanz | |
EP0505023B1 (en) | Synergistic, additive or antagonistic product selection test for biocides | |
EP0336281A1 (de) | Verfahren zur Steuerung biologischer Klärstufen | |
DE69535747T2 (de) | Medium zum Nachweis bestimmter Mikroben in einer Probe | |
EP1177319B1 (de) | Verfahren zum nachweisen von mikroorganismen in einer probe | |
AU2005217026B2 (en) | Measuring contamination | |
HUE035702T2 (en) | Detection and quantification of microorganisms | |
JP2002500020A (ja) | 嫌気性細菌の毒性化合物による阻止および殺害を迅速に評価する方法 | |
CN102725418B (zh) | 联用荧光底物和pH-敏感性荧光团用于荧光法检测微生物的生长培养基 | |
EP1341897B1 (de) | In situ-hybridisierungs-anordnung zum spezifischen nachweis von mikroorganismen | |
WO1998012348A9 (en) | Microbial monitoring device | |
DE60114459T3 (de) | Zusammensetzungen und Verfahren zum Nachweis von Mikroorganismen in einer Probe | |
Hoffman et al. | Measurement of the effects of cadmium stress on protozoan grazing of bacteria (bacterivory) in activated sludge by fluorescence microscopy | |
EP0244148A1 (en) | Method and device for enumerating microorganisms | |
Arshad et al. | Manipulation of different media and methods for cost-effective characterization of Escherichia coli strains collected from different habitats | |
DE10214153A1 (de) | Verfahren zum Nachweis von Mikroorganismen mittels in situ-Hybridisierung und Durchflusszytometrie |