JP2001527032A5 - - Google Patents
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- Publication number
- JP2001527032A5 JP2001527032A5 JP2000526199A JP2000526199A JP2001527032A5 JP 2001527032 A5 JP2001527032 A5 JP 2001527032A5 JP 2000526199 A JP2000526199 A JP 2000526199A JP 2000526199 A JP2000526199 A JP 2000526199A JP 2001527032 A5 JP2001527032 A5 JP 2001527032A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- skin
- sunscreen
- vitamin
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 description 304
- 239000000516 sunscreening agent Substances 0.000 description 96
- 230000000475 sunscreen effect Effects 0.000 description 89
- 239000003963 antioxidant agent Substances 0.000 description 86
- 235000006708 antioxidants Nutrition 0.000 description 86
- 210000003491 skin Anatomy 0.000 description 76
- 238000009472 formulation Methods 0.000 description 71
- 230000003078 antioxidant effect Effects 0.000 description 50
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 46
- -1 slisobenzone Chemical compound 0.000 description 45
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 39
- 239000003995 emulsifying agent Substances 0.000 description 33
- 230000004224 protection Effects 0.000 description 31
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 26
- 229920002498 Beta-glucan Polymers 0.000 description 26
- 102000019197 Superoxide Dismutase Human genes 0.000 description 26
- 108010012715 Superoxide dismutase Proteins 0.000 description 26
- 238000004519 manufacturing process Methods 0.000 description 26
- 229940087603 grape seed extract Drugs 0.000 description 25
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- 239000003921 oil Substances 0.000 description 25
- 239000001717 vitis vinifera seed extract Substances 0.000 description 25
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 23
- 239000000839 emulsion Substances 0.000 description 23
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 22
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 21
- 229930003268 Vitamin C Natural products 0.000 description 21
- 238000000034 method Methods 0.000 description 21
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- 239000011719 vitamin A Substances 0.000 description 21
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- 239000011718 vitamin C Substances 0.000 description 21
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 20
- 230000003833 cell viability Effects 0.000 description 20
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- 239000011709 vitamin E Substances 0.000 description 20
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- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 19
- 229940045997 vitamin a Drugs 0.000 description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 229930003427 Vitamin E Natural products 0.000 description 18
- 238000004113 cell culture Methods 0.000 description 18
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 18
- 230000005855 radiation Effects 0.000 description 18
- 229940046009 vitamin E Drugs 0.000 description 17
- 239000012071 phase Substances 0.000 description 16
- 238000011002 quantification Methods 0.000 description 16
- 150000002148 esters Chemical class 0.000 description 15
- 239000004615 ingredient Substances 0.000 description 15
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 description 15
- 150000003839 salts Chemical class 0.000 description 15
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 14
- 229960001173 oxybenzone Drugs 0.000 description 14
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 13
- 229960001679 octinoxate Drugs 0.000 description 13
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 12
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 12
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 12
- 239000002537 cosmetic Substances 0.000 description 12
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 12
- 235000019198 oils Nutrition 0.000 description 12
- 229940101267 panthenol Drugs 0.000 description 12
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- 239000011619 pantothenol Substances 0.000 description 12
- 239000003642 reactive oxygen metabolite Substances 0.000 description 12
- 229940108325 retinyl palmitate Drugs 0.000 description 12
- 235000019172 retinyl palmitate Nutrition 0.000 description 12
- 239000011769 retinyl palmitate Substances 0.000 description 12
- 238000012360 testing method Methods 0.000 description 12
- 235000014113 dietary fatty acids Nutrition 0.000 description 11
- 239000000194 fatty acid Substances 0.000 description 11
- 229930195729 fatty acid Natural products 0.000 description 11
- 230000009931 harmful effect Effects 0.000 description 11
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 11
- 229920001296 polysiloxane Polymers 0.000 description 11
- 229940042585 tocopherol acetate Drugs 0.000 description 11
- 239000007762 w/o emulsion Substances 0.000 description 11
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 description 10
- 229940085262 cetyl dimethicone Drugs 0.000 description 10
- SNPLKNRPJHDVJA-UHFFFAOYSA-N dl-panthenol Chemical compound OCC(C)(C)C(O)C(=O)NCCCO SNPLKNRPJHDVJA-UHFFFAOYSA-N 0.000 description 10
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 10
- 239000004166 Lanolin Substances 0.000 description 9
- 239000004205 dimethyl polysiloxane Substances 0.000 description 9
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 150000004665 fatty acids Chemical class 0.000 description 9
- 235000019388 lanolin Nutrition 0.000 description 9
- 230000001681 protective effect Effects 0.000 description 9
- MEZZCSHVIGVWFI-UHFFFAOYSA-N 2,2'-Dihydroxy-4-methoxybenzophenone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1O MEZZCSHVIGVWFI-UHFFFAOYSA-N 0.000 description 8
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 description 8
- 230000006378 damage Effects 0.000 description 8
- 229940008099 dimethicone Drugs 0.000 description 8
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 8
- 239000003974 emollient agent Substances 0.000 description 8
- 229960004881 homosalate Drugs 0.000 description 8
- 229940039717 lanolin Drugs 0.000 description 8
- CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 7
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 7
- 235000021355 Stearic acid Nutrition 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 7
- 229940100463 hexyl laurate Drugs 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 239000006210 lotion Substances 0.000 description 7
- 229940078752 magnesium ascorbyl phosphate Drugs 0.000 description 7
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 7
- 229910052708 sodium Inorganic materials 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 230000037072 sun protection Effects 0.000 description 7
- HTJNEBVCZXHBNJ-XCTPRCOBSA-H trimagnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;diphosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O HTJNEBVCZXHBNJ-XCTPRCOBSA-H 0.000 description 7
- 238000004078 waterproofing Methods 0.000 description 7
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 description 6
- 235000021314 Palmitic acid Nutrition 0.000 description 6
- 238000000692 Student's t-test Methods 0.000 description 6
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 6
- 229960004960 dioxybenzone Drugs 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 229940068171 ethyl hexyl salicylate Drugs 0.000 description 6
- 150000002191 fatty alcohols Chemical class 0.000 description 6
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 6
- 239000011777 magnesium Substances 0.000 description 6
- 229910052749 magnesium Inorganic materials 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 230000003020 moisturizing effect Effects 0.000 description 6
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 6
- 229960004838 phosphoric acid Drugs 0.000 description 6
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- 230000000699 topical effect Effects 0.000 description 6
- UEVAMYPIMMOEFW-UHFFFAOYSA-N trolamine salicylate Chemical compound OCCN(CCO)CCO.OC(=O)C1=CC=CC=C1O UEVAMYPIMMOEFW-UHFFFAOYSA-N 0.000 description 6
- 239000001993 wax Substances 0.000 description 6
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- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 5
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- 150000001298 alcohols Chemical class 0.000 description 5
- XNEFYCZVKIDDMS-UHFFFAOYSA-N avobenzone Chemical compound C1=CC(OC)=CC=C1C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1 XNEFYCZVKIDDMS-UHFFFAOYSA-N 0.000 description 5
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- 229910052700 potassium Inorganic materials 0.000 description 5
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- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical class CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 5
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- WYWZRNAHINYAEF-UHFFFAOYSA-N Padimate O Chemical compound CCCCC(CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-UHFFFAOYSA-N 0.000 description 2
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| US08/998,238 US6036946A (en) | 1997-12-24 | 1997-12-24 | Methods for protecting skin from damaging effects of ultraviolet light |
| US09/113,815 | 1998-07-10 | ||
| US08/998,238 | 1998-07-10 | ||
| US09/113,815 US6015548A (en) | 1998-07-10 | 1998-07-10 | High efficiency skin protection formulation with sunscreen agents and antioxidants |
| PCT/US1998/027433 WO1999033439A1 (en) | 1997-12-24 | 1998-12-22 | Composition with high efficiency skin protection from damaging effects of ultraviolet light |
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| JP2007332328A Division JP2008088188A (ja) | 1997-12-24 | 2007-12-25 | 紫外光の傷害作用からの高効率皮膚保護を備える組成物 |
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|---|---|
| JP2001527032A JP2001527032A (ja) | 2001-12-25 |
| JP2001527032A5 true JP2001527032A5 (enExample) | 2006-03-09 |
| JP4150501B2 JP4150501B2 (ja) | 2008-09-17 |
Family
ID=26811508
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000526199A Expired - Lifetime JP4150501B2 (ja) | 1997-12-24 | 1998-12-22 | 紫外光の傷害作用からの高効率皮膚保護を備える組成物 |
| JP2007332328A Pending JP2008088188A (ja) | 1997-12-24 | 2007-12-25 | 紫外光の傷害作用からの高効率皮膚保護を備える組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007332328A Pending JP2008088188A (ja) | 1997-12-24 | 2007-12-25 | 紫外光の傷害作用からの高効率皮膚保護を備える組成物 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1047392A4 (enExample) |
| JP (2) | JP4150501B2 (enExample) |
| AU (1) | AU1944599A (enExample) |
| CA (1) | CA2318345C (enExample) |
| WO (1) | WO1999033439A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9803936A (pt) * | 1998-09-08 | 2000-04-04 | Cosmeticos Natural Ind Com | Processo e composição para aumentar a ação de vitamina a na atividade celular de um indivìduo e uso de vitamina c. |
| BR9902972B1 (pt) * | 1999-07-16 | 2012-02-22 | Natura Cosméticos S.A. | composição bifásica de uso cosmético ou farmacêutico. |
| BRPI0003166B1 (pt) * | 1999-07-16 | 2015-08-25 | Natura Cosmeticos Sa | Processo para estabilização de compostos antioxidantes, e composições aquosas |
| ES2161161B1 (es) * | 1999-08-30 | 2002-07-01 | Consejo Superior Investigacion | Extracto de uva para proteccion solar. |
| GB9921238D0 (en) * | 1999-09-09 | 1999-11-10 | Boots Co Plc | Skincare composition |
| US6358517B1 (en) * | 1999-10-22 | 2002-03-19 | Unilever Home & Personal Care Usa, Division Of Conopco | Cosmetic compositions containing resveratrol and retinoids |
| CN1111068C (zh) * | 2000-07-27 | 2003-06-11 | 上海北医大生物科技有限公司 | 一种葡萄籽提取物opc强抗氧化复合胶囊及其制造方法 |
| FR2812190B1 (fr) * | 2000-07-28 | 2003-01-31 | Oreal | Utilisation d'agonistes non prostanoiques des recepteurs des prostaglandines ep-2 et/ou ep-4 comme agent cosmetique permettant d'attenuer, de diminuer ou d'arreter la chute des cheveux et des poils |
| FR2812192B1 (fr) * | 2000-07-28 | 2003-01-31 | Oreal | Utilisation d'antagonistes de recepteur des prostaglandines ep-3 comme agent cosmetique permettant d'attenuer, de diminuer ou d'arreter la chute des cheveux et des poils |
| JP2002204687A (ja) * | 2000-11-09 | 2002-07-23 | Onaka Yasushi | β−１．３−１．６グルカン（アウレオバシジウム培養液）の医療、保健、福祉、食品および各種産業分野での応用 |
| JP4824181B2 (ja) * | 2001-02-13 | 2011-11-30 | 日本メナード化粧品株式会社 | 皮膚外用剤 |
| US6436378B1 (en) * | 2001-02-28 | 2002-08-20 | Colgate-Palmolive Company | Composition |
| EP1398019A1 (de) * | 2002-09-13 | 2004-03-17 | Cognis France S.A. | Verfahren zum Schutz und zur Modulation von Dermal Epidermal Junctions |
| FR2845002B1 (fr) * | 2002-09-30 | 2004-11-05 | Oreal | Composition cosmetique ou dermatologique contenant un derive d'acide ascorbique et un filtre |
| JP2006525945A (ja) * | 2003-05-16 | 2006-11-16 | 美時化学製薬股▲ふん▼有限公司 | 皮膚を通して投薬される外用組成物 |
| ITMI20040402A1 (it) | 2004-03-03 | 2004-06-03 | Isagro Spa | Miscele e metodo per l'induzione di resistenza nella pianta |
| ES2582485T3 (es) * | 2004-09-29 | 2016-09-13 | Basf Se | Composiciones cosméticas o dermatológicas fotoestables |
| US7348034B2 (en) * | 2005-03-07 | 2008-03-25 | Access Business Group International Llc | Plant based formulations for improving skin moisture, texture, and appearance |
| EP1959913A1 (en) | 2005-12-09 | 2008-08-27 | DSMIP Assets B.V. | Stabilizing composition |
| KR20090009513A (ko) * | 2007-07-20 | 2009-01-23 | 한국원자력연구원 | 방사선 조사에 의한 저 분자량의 베타글루칸의 제조 방법및 방사선 조사에 의하여 제조된 저 분자량의 베타글루칸 |
| US8427384B2 (en) | 2007-09-13 | 2013-04-23 | Aerosat Corporation | Communication system with broadband antenna |
| EP2229180A1 (en) * | 2007-12-27 | 2010-09-22 | D.M.G. Italia Srl | Composition comprising superoxide dismutase and carboxv methyl beta-1,3 glucan |
| CN103394088B (zh) | 2008-01-25 | 2017-01-18 | Msd 消费保健品公司 | 选择用于局部施用组合物的抗氧化剂的方法 |
| EP2284281A4 (en) | 2008-03-28 | 2011-08-10 | Sysmex Corp | REAGENT COMPRISING A PRIMER FOR THE DETECTION OF MRM FOR CYTOKERATIN-7 |
| ITMI20080560A1 (it) * | 2008-04-01 | 2009-10-02 | Lodovico Gianluca Braguti | Composizioni preventive-protettive contro l'insorgenza di manifestazioni cutanee fotoallergiche e fototossiche |
| EP2135598B1 (en) * | 2008-06-16 | 2011-08-03 | Rohm and Haas Company | Particle Containing Ultraviolet Absorber |
| WO2010042991A1 (en) * | 2008-10-15 | 2010-04-22 | Novogen Research Pty Ltd | Methods of treatment utilising glucan formulations |
| US9126061B2 (en) * | 2008-11-12 | 2015-09-08 | June Jacobs Laboratories, Llc | Antioxidant compositions for the cleansing and conditioning of skin |
| EP2263481A1 (en) | 2009-05-29 | 2010-12-22 | Nestec S.A. | Green tea extracts of improved bioavailability |
| BR112013032410A2 (pt) * | 2011-06-24 | 2017-01-17 | Epitogenesis Inc | composições farmacêuticas compreendendo uma combinação de veículos, vitaminas, taninos e flavonoides de seleção como imunomoduladores específicos de antígeno |
| CN102793642B (zh) * | 2012-08-28 | 2014-01-15 | 广州丹奇日用化工厂有限公司 | 一种护肤品组合物 |
| JP2014162756A (ja) * | 2013-02-26 | 2014-09-08 | Kowa Company Ltd | パンテノール類を含有する含水組成物 |
| CN103520058B (zh) * | 2013-10-18 | 2015-03-25 | 山东省农业科学院农产品研究所 | 一种蚕蛹活性多肽晒后修复凝露及其制备方法 |
| CN103690450B (zh) * | 2013-12-20 | 2016-04-20 | 中兴能源（天津）有限公司 | 具有美白抗衰老功效的组合物、护肤品及制备方法与应用 |
| US20150202145A1 (en) * | 2014-01-21 | 2015-07-23 | Md Solarciences Corp. | Sunscreen composition with improved aesthetic properties |
| CN107106462A (zh) * | 2014-12-15 | 2017-08-29 | 荷兰联合利华有限公司 | 用于提供改进的防晒保护的组合物 |
| AR102008A1 (es) * | 2015-09-24 | 2017-01-25 | Brix S R L | Ingrediente farmacéutico activo (ifa) oleoso para el tratamiento de afecciones de la piel, composiciones que lo comprenden y su uso para prepararlas |
| WO2018017518A2 (en) | 2016-07-21 | 2018-01-25 | Astronics Aerosat Corporation | Multi-channel communications antenna |
| FR3060383B1 (fr) * | 2016-12-21 | 2019-10-18 | L'oreal | Composition contenant une phase huileuse continue, un filtre uv liquide ss,ss-diphenylacrylate, un filtre uv liquide salicylate et une huile siliconee volatile non cyclique |
| US10992052B2 (en) | 2017-08-28 | 2021-04-27 | Astronics Aerosat Corporation | Dielectric lens for antenna system |
| US20210322297A9 (en) * | 2018-02-23 | 2021-10-21 | Givaudan Italia S.P.A | Cosmetic compositions for protection against light-induced damages |
| JP2022508832A (ja) * | 2018-10-18 | 2022-01-19 | ベク クリニカル インコーポレイテッド | 高効力ビタミンｃ局所用製剤 |
| ES2776773A1 (es) * | 2019-01-31 | 2020-07-31 | Actigolden S L | Composicion protectora del color y el olor |
| JP2020158493A (ja) * | 2019-03-20 | 2020-10-01 | ジャパンメディック株式会社 | パンテノールを含有する油中水型（ｗ／ｏ型）クリーム |
| KR102182966B1 (ko) * | 2019-05-02 | 2020-11-25 | 주식회사 비타월드 | 비타민 복합체 조성물, 이를 포함하는 코어-쉘 구조의 복합비타민, 이의 제조방법 및 이를 포함하는 화장료 조성물 |
| WO2021212075A1 (en) | 2020-04-16 | 2021-10-21 | Baek Clinical Inc. | Stabilizing vitamin c application formulations |
| US11696888B2 (en) | 2020-05-27 | 2023-07-11 | Mary Kay Inc. | Topical compositions and methods |
| US11572420B1 (en) | 2021-07-30 | 2023-02-07 | Tissue repair ltd | Isolated biological polysaccharide compound, methods of use and methods of manufacture thereof |
| US11384160B1 (en) | 2021-07-30 | 2022-07-12 | Tissue repair ltd | Method of making a beta glucan compound |
| CN113952250B (zh) * | 2021-11-02 | 2023-11-21 | 上海忱扬生物科技有限公司 | 一种稳定的抗光老化组合物及其制备方法 |
| US20230233467A1 (en) * | 2022-01-24 | 2023-07-27 | Nutraceutical Corporation | Multiple nutrient liposomal supplement and methods of manufacturing the same |
| WO2024262012A1 (ja) * | 2023-06-23 | 2024-12-26 | 株式会社アンプリー | 炭酸ガスパック用キット |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5158772A (en) * | 1991-09-23 | 1992-10-27 | Davis Walter B | Unique bacterial polysaccharide polymer gel in cosmetics, pharmaceuticals and foods |
| US5279817A (en) * | 1992-10-02 | 1994-01-18 | Ricardo Franco | Suntanning oil formulation containing annatto |
| JP3770922B2 (ja) * | 1993-05-28 | 2006-04-26 | 株式会社コーセー | 皮膚外用剤 |
| GB9403153D0 (en) * | 1994-02-18 | 1994-04-06 | Ciba Geigy Ag | Cosmetic compositions |
| US5505935A (en) * | 1994-05-09 | 1996-04-09 | Elizabeth Arden Company, Division Of Conopco, Inc. | Sunscreen compositions |
| US5486352A (en) * | 1995-01-03 | 1996-01-23 | Elizabeth Arden Company | Sunscreen compositions |
| AUPN166195A0 (en) * | 1995-03-13 | 1995-04-06 | Norvet Research Pty Limited | Process for glucan extraction |
| US5609854A (en) * | 1995-06-06 | 1997-03-11 | Elizabeth Arden Company, Division Of Conopco, Inc. | Thickened and stabilized cosmetic emulsion compositions |
| AU2741197A (en) * | 1996-04-22 | 1997-11-12 | Henkel Corporation | Natural antioxidant composition |
-
1998
- 1998-12-22 JP JP2000526199A patent/JP4150501B2/ja not_active Expired - Lifetime
- 1998-12-22 EP EP98964275A patent/EP1047392A4/en not_active Withdrawn
- 1998-12-22 CA CA2318345A patent/CA2318345C/en not_active Expired - Lifetime
- 1998-12-22 WO PCT/US1998/027433 patent/WO1999033439A1/en not_active Ceased
- 1998-12-22 AU AU19445/99A patent/AU1944599A/en not_active Abandoned
-
2007
- 2007-12-25 JP JP2007332328A patent/JP2008088188A/ja active Pending
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