|
US6602864B1
(en)
*
|
1996-12-13 |
2003-08-05 |
Aventis Pharma Deutschland Gmbh |
Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds
|
|
EP1009758B1
(en)
*
|
1997-08-29 |
2005-06-01 |
Tularik Limited |
Meta-benzamidine derivatives as serine protease inhibitors
|
|
AU753675B2
(en)
*
|
1998-03-19 |
2002-10-24 |
Ajinomoto Co., Inc. |
Aminoisoquinoline derivatives
|
|
WO2000009480A1
(en)
*
|
1998-08-11 |
2000-02-24 |
Daiichi Pharmaceutical Co., Ltd. |
Novel sulfonyl derivatives
|
|
ES2209337T3
(es)
|
1998-08-14 |
2004-06-16 |
Pfizer Inc. |
Agentes antitromboticos.
|
|
TW575567B
(en)
*
|
1998-10-23 |
2004-02-11 |
Akzo Nobel Nv |
Serine protease inhibitor
|
|
EP1058549A4
(en)
*
|
1998-12-23 |
2003-11-12 |
Bristol Myers Squibb Pharma Co |
FACTOR Xa OR THROMBIN INHIBITORS
|
|
KR20000047461A
(ko)
*
|
1998-12-29 |
2000-07-25 |
성재갑 |
트롬빈 억제제
|
|
US6653316B1
(en)
|
1999-05-19 |
2003-11-25 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
|
|
US6750342B1
(en)
|
1999-05-19 |
2004-06-15 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
|
|
US6716838B1
(en)
|
1999-05-19 |
2004-04-06 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents
|
|
MXPA01011805A
(es)
*
|
1999-05-19 |
2003-09-04 |
Pharmacia Corp |
Aril y heteroaril piridonas policiclicas, substituidas utiles para la inhibicion selectiva de la cascada de coagulacion.
|
|
US7015230B1
(en)
|
1999-05-19 |
2006-03-21 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
|
|
US6458952B1
(en)
|
1999-05-19 |
2002-10-01 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
|
|
US6867217B1
(en)
|
1999-05-19 |
2005-03-15 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
|
|
US6664255B1
(en)
|
1999-05-19 |
2003-12-16 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
|
|
WO2000071493A2
(en)
*
|
1999-05-24 |
2000-11-30 |
Cor Therapeutics, Inc. |
INHIBITORS OF FACTOR Xa
|
|
GB9929552D0
(en)
*
|
1999-12-14 |
2000-02-09 |
Proteus Molecular Design |
Compounds
|
|
WO2000076970A2
(en)
*
|
1999-06-14 |
2000-12-21 |
Eli Lilly And Company |
Serine protease inhibitors
|
|
CA2375920A1
(en)
*
|
1999-06-14 |
2000-12-21 |
Eli Lilly And Company |
Compounds
|
|
JP2003519120A
(ja)
*
|
1999-12-27 |
2003-06-17 |
オーソーマクニール ファーマシューティカル， インコーポレイテッド |
卵胞刺激ホルモンの拮抗物質としての置換したアミノアルキルアミド誘導体
|
|
WO2001068605A1
(en)
|
2000-03-13 |
2001-09-20 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
|
|
EP1267876A1
(en)
|
2000-03-23 |
2003-01-02 |
Merck & Co., Inc. |
Thrombin inhibitors
|
|
EP1268428A2
(en)
|
2000-04-05 |
2003-01-02 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade
|
|
US6875791B2
(en)
|
2000-04-05 |
2005-04-05 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
|
|
EP1274676A2
(en)
|
2000-04-17 |
2003-01-15 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade
|
|
SI20582A
(sl)
*
|
2000-05-05 |
2001-12-31 |
Univerza V Ljubljani |
Novi inhibitorji trombina, njihova priprava in uporaba
|
|
AU2001256733A1
(en)
*
|
2000-05-16 |
2001-11-26 |
Takeda Chemical Industries Ltd. |
Melanin-concentrating hormone antagonist
|
|
WO2001087851A1
(en)
*
|
2000-05-18 |
2001-11-22 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
|
|
GB0030305D0
(en)
|
2000-12-13 |
2001-01-24 |
Lilly Co Eli |
Compounds
|
|
US7074934B2
(en)
|
2000-06-13 |
2006-07-11 |
Tularik Limited |
Serine protease inhibitors
|
|
GB0030304D0
(en)
|
2000-12-13 |
2001-01-24 |
Lilly Co Eli |
Compounds
|
|
GB0030306D0
(en)
|
2000-12-13 |
2001-01-24 |
Lilly Co Eli |
Compounds
|
|
GB0030303D0
(en)
|
2000-12-13 |
2001-01-24 |
Lilly Co Eli |
Compounds
|
|
WO2002004423A1
(en)
|
2000-07-12 |
2002-01-17 |
Akzo Nobel N.V. |
Thrombin inhibitors comprising an aminoisoquinoline group
|
|
US6906192B2
(en)
|
2000-11-07 |
2005-06-14 |
Bristol Myers Squibb Company |
Processes for the preparation of acid derivatives useful as serine protease inhibitors
|
|
HUP0400651A2
(hu)
|
2000-11-07 |
2004-06-28 |
Bristol-Myers Squibb Company |
Szerin proteáz inhibitorokként alkalmazható savszármazékok és ezeket tartalmazó gyógyszerkészítmények
|
|
US7015223B1
(en)
|
2000-11-20 |
2006-03-21 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade
|
|
WO2002042272A2
(en)
|
2000-11-20 |
2002-05-30 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
|
|
US7119094B1
(en)
|
2000-11-20 |
2006-10-10 |
Warner-Lambert Company |
Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
|
|
GB0114185D0
(en)
|
2001-06-12 |
2001-08-01 |
Protherics Molecular Design Lt |
Compounds
|
|
JP2004518688A
(ja)
|
2001-01-30 |
2004-06-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
ファクターＸａ阻害剤のスルホンアミドラクタムおよびその方法
|
|
GB0114004D0
(en)
|
2001-06-08 |
2001-08-01 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0114005D0
(en)
|
2001-06-08 |
2001-08-01 |
Glaxo Group Ltd |
Chemical compounds
|
|
US6905813B2
(en)
*
|
2001-08-29 |
2005-06-14 |
Chugai Photo Chemical Co., Ltd. |
Processing agent for silver halide color photosensitive material and processing method thereof
|
|
MXPA04003170A
(es)
|
2001-10-03 |
2004-07-08 |
Pharmacia Corp |
Compuestos policiclicos, sustituidos, provisto de 5 miembros, utiles para la inhibicion selectiva de la cascada de coagulacion.
|
|
CA2462305A1
(en)
|
2001-10-03 |
2003-04-10 |
Michael S. South |
6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade
|
|
WO2004072102A2
(en)
*
|
2003-02-11 |
2004-08-26 |
Bristol-Myers Squibb Company |
Benzene acetamide compounds useful as serine protease inhibitors
|
|
US7122559B2
(en)
*
|
2003-02-11 |
2006-10-17 |
Bristol-Myers Squibb Company |
Phenylglycine derivatives useful as serine protease inhibitors
|
|
US20070179155A1
(en)
*
|
2003-06-20 |
2007-08-02 |
Brian Smith |
N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
|
|
US7202363B2
(en)
|
2003-07-24 |
2007-04-10 |
Abbott Laboratories |
Thienopyridine and furopyridine kinase inhibitors
|
|
JPWO2006064780A1
(ja)
*
|
2004-12-14 |
2008-06-12 |
塩野義製薬株式会社 |
便秘治療剤
|
|
US8193359B2
(en)
|
2004-12-24 |
2012-06-05 |
Prosidion Limited |
G-protein coupled receptor agonists
|
|
ATE479676T1
(de)
*
|
2005-01-10 |
2010-09-15 |
Bristol Myers Squibb Co |
Als antikoagulanzien verwendbare phenylglycinamid-derivate
|
|
GB0507577D0
(en)
|
2005-04-14 |
2005-05-18 |
Novartis Ag |
Organic compounds
|
|
DE602006011752D1
(de)
*
|
2005-06-24 |
2010-03-04 |
Bristol Myers Squibb Co |
Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate
|
|
TWI389899B
(zh)
*
|
2006-08-08 |
2013-03-21 |
Msd Oss Bv |
具口服活性之凝血酶抑制劑
|
|
AR063258A1
(es)
*
|
2006-10-13 |
2009-01-14 |
Actelion Pharmaceuticals Ltd |
Derivados de 2-aminocarbonil-piridina, una composicion farmaceutica que los contiene y su uso en la preparacion de un medicamento para el tratamiento de trastornos vasculares oclusivos.
|
|
US8247403B2
(en)
|
2007-03-07 |
2012-08-21 |
Takeda Pharmaceutical Company Limited |
Benzoxazepine derivatives and use thereof
|
|
WO2008144483A2
(en)
*
|
2007-05-18 |
2008-11-27 |
Armgo Pharma, Inc. |
Agents for treating disorders involving modulation of ryanodine receptors
|
|
EP2138495A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
|
|
EP2138485A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted N-Oxide pyrazine derivatives
|
|
EP2138493A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidone derivatives
|
|
EP2138492A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidin-4-one derivatives
|
|
EP2138498A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted tricyclic derivatives against neurodegenerative diseases
|
|
EP2138494A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted alkyl pyrimidin-4-one derivatives
|
|
EP2138488A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
|
|
CN101684077B
(zh)
|
2008-09-24 |
2013-01-02 |
浙江九洲药业股份有限公司 |
N-酰基联苯丙氨酸的制备方法
|
|
CN101774941A
(zh)
|
2009-01-13 |
2010-07-14 |
浙江九洲药业股份有限公司 |
2-酰基氨基-3-联苯基丙酸的制备及拆分方法
|
|
CN101555211B
(zh)
*
|
2009-05-13 |
2012-01-25 |
浙江九洲药业股份有限公司 |
2-酰基氨基-3-联苯基丙酸的化学合成方法
|
|
EP2480523B1
(en)
*
|
2009-09-23 |
2017-03-01 |
Zhejiang Jiuzhou Pharmaceutical Co., Ltd. |
Process for manufacture of n-acylbphenyl alanine
|
|
WO2012015949A2
(en)
*
|
2010-07-29 |
2012-02-02 |
Joule Unlimited Technologies, Inc. |
Methods and compositions for improving yields of reduced products of photosynthetic microorganisms
|
|
MY182666A
(en)
|
2010-11-05 |
2021-01-28 |
Senomyx Inc |
Compounds useful as modulators of trpm8
|
|
EP2606893A1
(en)
*
|
2011-12-21 |
2013-06-26 |
Sanofi |
Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application
|
|
WO2014188211A1
(en)
|
2013-05-23 |
2014-11-27 |
Kalvista Pharmaceuticals Limited |
Heterocyclic derivates
|
|
ITUB20150417A1
(it)
*
|
2015-05-08 |
2016-11-08 |
Dipharma Francis Srl |
Procedimento per la preparazione di composti piperidinici
|
|
JP6865743B2
(ja)
|
2015-10-01 |
2021-04-28 |
フィルメニッヒ インコーポレイテッドＦｉｒｍｅｎｉｃｈ Ｉｎｃｏｒｐｏｒａｔｅｄ |
Ｔｒｐｍ８の活性調節因子として有用な化合物
|
|
GB201805174D0
(en)
*
|
2018-03-29 |
2018-05-16 |
Univ Leeds Innovations Ltd |
Compounds
|
|
GB201807014D0
(en)
*
|
2018-04-30 |
2018-06-13 |
Univ Leeds Innovations Ltd |
Factor xlla inhibitors
|
|
SMT202400527T1
(it)
|
2019-07-01 |
2025-01-14 |
Tonix Pharma Ltd |
Anticorpi anti-cd154 e loro usi
|
|
CA3147564A1
(en)
*
|
2019-08-21 |
2021-02-25 |
Kalvista Pharmaceuticals Limited |
Enzyme inhibitors
|
|
CN114258392A
(zh)
*
|
2019-08-21 |
2022-03-29 |
卡尔维斯塔制药有限公司 |
酶抑制剂
|
|
AR121715A1
(es)
*
|
2020-04-03 |
2022-06-29 |
Biocryst Pharm Inc |
Pirrolopirimidinaminas como inhibidores del sistema del complemento
|
|
CA3207098A1
(en)
|
2021-01-06 |
2022-07-14 |
Tonix Pharma Limited |
Methods of inducing immune tolerance with modified anti-cd154 antibodies
|
|
WO2024044098A2
(en)
*
|
2022-08-23 |
2024-02-29 |
Alexion Pharmaceuticals, Inc. |
Pharmaceutical compounds for the treatment of complement mediated disorders
|
|
WO2025248134A1
(en)
|
2024-05-31 |
2025-12-04 |
Tonix Pharma Limited |
Treatment methods comprising administration of modified cd154 antibodies
|
|
CN119954681A
(zh)
*
|
2025-02-05 |
2025-05-09 |
南京工业大学 |
一种小分子光交联剂、制备方法及应用
|