JP2001518509A5 - - Google Patents
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- Publication number
- JP2001518509A5 JP2001518509A5 JP2000514650A JP2000514650A JP2001518509A5 JP 2001518509 A5 JP2001518509 A5 JP 2001518509A5 JP 2000514650 A JP2000514650 A JP 2000514650A JP 2000514650 A JP2000514650 A JP 2000514650A JP 2001518509 A5 JP2001518509 A5 JP 2001518509A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor antagonist
- composition
- pharmaceutical composition
- glucocorticoid receptor
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003850 glucocorticoid receptor antagonist Substances 0.000 description 15
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- 239000000203 mixture Substances 0.000 description 13
- 229940126013 glucocorticoid receptor antagonist Drugs 0.000 description 11
- 208000028017 Psychotic disease Diseases 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 208000024714 major depressive disease Diseases 0.000 description 4
- VKHAHZOOUSRJNA-GCNJZUOMSA-N mifepristone Chemical compound C1([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=CC=C(N(C)C)C=C1 VKHAHZOOUSRJNA-GCNJZUOMSA-N 0.000 description 3
- 229960003248 mifepristone Drugs 0.000 description 3
- 150000003431 steroids Chemical group 0.000 description 3
- 208000014311 Cushing syndrome Diseases 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 201000009395 primary hyperaldosteronism Diseases 0.000 description 2
- 208000020016 psychiatric disease Diseases 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 208000022497 Cocaine-Related disease Diseases 0.000 description 1
- 201000006145 cocaine dependence Diseases 0.000 description 1
- -1 dimethylaminophenyl moiety Chemical group 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6097397P | 1997-10-06 | 1997-10-06 | |
| US60/060,973 | 1997-10-06 | ||
| PCT/US1998/020906 WO1999017779A1 (en) | 1997-10-06 | 1998-10-05 | Methods for treating psychosis associated with glucocorticoid related dysfunction |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008271442A Division JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Division JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001518509A JP2001518509A (ja) | 2001-10-16 |
| JP2001518509A5 true JP2001518509A5 (enExample) | 2006-01-05 |
Family
ID=22032889
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000514650A Withdrawn JP2001518509A (ja) | 1997-10-06 | 1998-10-05 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2008271442A Withdrawn JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008271442A Withdrawn JP2009051858A (ja) | 1997-10-06 | 2008-10-21 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
| JP2009071039A Expired - Fee Related JP5180125B2 (ja) | 1997-10-06 | 2009-03-23 | グルココルチコイド関連機能不全に関連した精神病の処置のための方法。 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6150349A (enExample) |
| EP (1) | EP1023074B1 (enExample) |
| JP (3) | JP2001518509A (enExample) |
| KR (2) | KR100840957B1 (enExample) |
| CN (3) | CN1528315A (enExample) |
| AT (1) | ATE332696T1 (enExample) |
| AU (1) | AU747956B2 (enExample) |
| CA (1) | CA2302586C (enExample) |
| CY (1) | CY1106330T1 (enExample) |
| DE (1) | DE69835225T2 (enExample) |
| DK (1) | DK1023074T3 (enExample) |
| ES (1) | ES2268792T3 (enExample) |
| IL (2) | IL135469A0 (enExample) |
| NO (1) | NO327233B1 (enExample) |
| NZ (1) | NZ503250A (enExample) |
| PT (1) | PT1023074E (enExample) |
| WO (1) | WO1999017779A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0903146A1 (en) * | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6620802B1 (en) * | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| SI1325022T1 (sl) * | 2000-09-18 | 2007-04-30 | Applied Research Systems | Metoda za pripravo 21-hidroksi-6,19-oksidoprogesterona (21oh-6op) |
| CN1820756A (zh) | 2001-03-23 | 2006-08-23 | 科塞普特治疗公司 | 使用糖皮质激素受体特效拮抗剂治疗压力症的方法 |
| EP1390037B1 (en) * | 2001-05-04 | 2010-12-22 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor-specific antagonists for the treatment of delirium |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| WO2003009853A1 (en) * | 2001-07-23 | 2003-02-06 | Corcept Therapeutics, Inc. | Methods for preventing antipsychotic-induced weight gain |
| NZ531477A (en) | 2001-08-31 | 2006-10-27 | Corcept Therapeutics Inc | Use of a glucocorticoid receptor antagonist comprising a steroidal skeleton with at least one phenyl-containing moiety in the 11-beta position of the steroidal skeleton to decrease cognitive deterioration in adults with Down's syndrome |
| DE60230936D1 (de) * | 2001-10-26 | 2009-03-05 | Organon Nv | Verwendung von (11beta, 17beta)-11-(1,3-Benzodioxol-5-yl)-17-Hydroxy-17-(1-Propinyl)-estra-4,9-dien-3-on zur Behandlung von schweren Depressionen |
| AU2002366217A1 (en) * | 2001-11-23 | 2003-06-10 | Akzo Nobel N.V. | Treatment of major depressive disorder using glucocorticoid receptor antagonists |
| US7326697B2 (en) * | 2002-04-29 | 2008-02-05 | Corcept Therapeutics, Inc. | Methods for increasing the therapeutic response to electroconvulsive therapy |
| WO2004004653A2 (en) * | 2002-07-02 | 2004-01-15 | Corcept Therapeutics, Inc. | Methods for treating psychosis associated with interferon-alpha therapy |
| AU2003299311A1 (en) * | 2002-12-18 | 2004-07-09 | University Of Zurich | Treatment of neuro-psychiatric disorders |
| US20040229855A1 (en) * | 2003-02-04 | 2004-11-18 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of postpartum psychosis |
| US8097606B2 (en) * | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| WO2006060736A2 (en) * | 2004-12-03 | 2006-06-08 | The Children's Hospital Of Philadelphia | A composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug |
| CN100588393C (zh) * | 2004-12-15 | 2010-02-10 | 上海三合生物技术有限公司 | 赛米司酮类用于治疗抑郁症的用途 |
| US20060229505A1 (en) * | 2005-04-08 | 2006-10-12 | Mundt James C | Method and system for facilitating respondent identification with experiential scaling anchors to improve self-evaluation of clinical treatment efficacy |
| JP2009535430A (ja) * | 2006-05-02 | 2009-10-01 | コーセプト セラピューティクス， インコーポレイテッド | Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用 |
| EP1987814A1 (en) * | 2007-04-30 | 2008-11-05 | Exelgyn | Mifepristone pharmaceutical compositions and their methods of preparation |
| RU2327448C1 (ru) | 2007-05-23 | 2008-06-27 | Виктор Иванович Рощин | Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов |
| WO2008157460A1 (en) * | 2007-06-15 | 2008-12-24 | Cook, Kevin, M. | Androstane and pregnane steroids with potent allosteric gaba receptor chloride ionophore modulating properties |
| US11103514B2 (en) * | 2010-05-26 | 2021-08-31 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| JP5804395B2 (ja) * | 2011-02-03 | 2015-11-04 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| EP3265127B1 (en) * | 2015-03-02 | 2024-02-21 | Corcept Therapeutics, Inc. | Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| EP3297728A4 (en) * | 2015-05-18 | 2019-07-03 | Corcept Therapeutics Incorporated | METHOD FOR DIAGNOSIS AND ASSESSMENT OF THE TREATMENT OF THE CUSHING SYNDROME |
| CN114680890A (zh) * | 2016-10-21 | 2022-07-01 | 西铁城时计株式会社 | 检测装置 |
| KR20210153056A (ko) | 2019-03-18 | 2021-12-16 | 리네트 케이. 니만 | 인슐린 감수성 개선 방법 |
| WO2021119432A1 (en) | 2019-12-11 | 2021-06-17 | Corcept Therapeutics Incorporated | Methods of treating antipsychotic-induced weight gain with miricorilant |
| US11878025B2 (en) * | 2021-09-06 | 2024-01-23 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| FR2739029B1 (fr) * | 1995-09-21 | 1997-11-21 | Roussel Uclaf | Nouvelle application therapeutique des composes antimineralo-corticoides |
| CA2250874A1 (en) * | 1996-04-09 | 1997-10-16 | Btg International Limited | Use of 7 alpha-substituted steroids to treat neuropsychiatric, immune or endocrine disorders |
| FR2757400B1 (fr) * | 1996-12-19 | 1999-12-17 | Hoechst Marion Roussel Inc | Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs |
-
1998
- 1998-10-05 DK DK98950911T patent/DK1023074T3/da active
- 1998-10-05 KR KR1020077003769A patent/KR100840957B1/ko not_active Expired - Fee Related
- 1998-10-05 EP EP98950911A patent/EP1023074B1/en not_active Expired - Lifetime
- 1998-10-05 AU AU96832/98A patent/AU747956B2/en not_active Ceased
- 1998-10-05 CA CA002302586A patent/CA2302586C/en not_active Expired - Fee Related
- 1998-10-05 CN CNA200410039908XA patent/CN1528315A/zh active Pending
- 1998-10-05 KR KR1020007003683A patent/KR100804558B1/ko not_active Expired - Fee Related
- 1998-10-05 DE DE69835225T patent/DE69835225T2/de not_active Expired - Lifetime
- 1998-10-05 WO PCT/US1998/020906 patent/WO1999017779A1/en not_active Ceased
- 1998-10-05 ES ES98950911T patent/ES2268792T3/es not_active Expired - Lifetime
- 1998-10-05 AT AT98950911T patent/ATE332696T1/de active
- 1998-10-05 JP JP2000514650A patent/JP2001518509A/ja not_active Withdrawn
- 1998-10-05 IL IL13546998A patent/IL135469A0/xx active IP Right Grant
- 1998-10-05 NZ NZ503250A patent/NZ503250A/en not_active IP Right Cessation
- 1998-10-05 CN CNB988097923A patent/CN1187053C/zh not_active Expired - Fee Related
- 1998-10-05 PT PT98950911T patent/PT1023074E/pt unknown
- 1998-10-05 CN CNA2006101003657A patent/CN1919199A/zh active Pending
-
1999
- 1999-02-04 US US09/244,457 patent/US6150349A/en not_active Expired - Lifetime
-
2000
- 2000-04-04 IL IL135469A patent/IL135469A/en not_active IP Right Cessation
- 2000-04-05 NO NO20001744A patent/NO327233B1/no not_active IP Right Cessation
- 2000-08-15 US US09/639,377 patent/US6362173B1/en not_active Expired - Lifetime
-
2006
- 2006-10-05 CY CY20061101439T patent/CY1106330T1/el unknown
-
2008
- 2008-10-21 JP JP2008271442A patent/JP2009051858A/ja not_active Withdrawn
-
2009
- 2009-03-23 JP JP2009071039A patent/JP5180125B2/ja not_active Expired - Fee Related
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