AU747956B2 - Methods for treating psychosis associated with glucocorticoid related dysfunction - Google Patents
Methods for treating psychosis associated with glucocorticoid related dysfunction Download PDFInfo
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- AU747956B2 AU747956B2 AU96832/98A AU9683298A AU747956B2 AU 747956 B2 AU747956 B2 AU 747956B2 AU 96832/98 A AU96832/98 A AU 96832/98A AU 9683298 A AU9683298 A AU 9683298A AU 747956 B2 AU747956 B2 AU 747956B2
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- psychosis
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- receptor antagonist
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Public Health (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Epidemiology (AREA)
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- Organic Chemistry (AREA)
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- Psychiatry (AREA)
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- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| AU9683298A AU9683298A (en) | 1999-04-27 |
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| CN (3) | CN1187053C (enExample) |
| AT (1) | ATE332696T1 (enExample) |
| AU (1) | AU747956B2 (enExample) |
| CA (1) | CA2302586C (enExample) |
| CY (1) | CY1106330T1 (enExample) |
| DE (1) | DE69835225T2 (enExample) |
| DK (1) | DK1023074T3 (enExample) |
| ES (1) | ES2268792T3 (enExample) |
| IL (2) | IL135469A0 (enExample) |
| NO (1) | NO327233B1 (enExample) |
| NZ (1) | NZ503250A (enExample) |
| PT (1) | PT1023074E (enExample) |
| WO (1) | WO1999017779A1 (enExample) |
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| EP0903146A1 (en) * | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6620802B1 (en) * | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| AU1817902A (en) * | 2000-09-18 | 2002-03-26 | Applied Research Systems | Method for the preparation of 21-hydroxy-6,19-oxidoprogesterone (21oh-6op) |
| NZ528147A (en) * | 2001-03-23 | 2005-06-24 | Corcept Therapeutics Inc | Methods for treating stress disorders using glucocorticoid receptor-specific antagonists |
| WO2002096433A1 (en) * | 2001-05-04 | 2002-12-05 | Corcept Therapeutics, Inc. | Methods for treating delirium using glucocorticoid receptor-specific antagonists |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| JP2004537563A (ja) | 2001-07-23 | 2004-12-16 | コーセプト セラピューティクス， インコーポレイテッド | 抗神経病薬誘導性体重増加を予防するための方法 |
| MXPA04001893A (es) * | 2001-08-31 | 2005-03-07 | Corcept Therapeutics Inc | Metodos para inhibir deterioro cognoscitivo en adultos con sindrome de down. |
| BR0213466A (pt) * | 2001-10-26 | 2004-11-09 | Akzo Nobel Nv | Uso de (11beta,17beta)-11-(1,3- benzodioxol-s-il)-17-hidróxi-17-(1-propinil) estra-4,9-dien-3-ona, preparação farmacêutica, e, método para o tratamento de um paciente sofrendo de distúrbio depressivo grave |
| JP2005513024A (ja) * | 2001-11-23 | 2005-05-12 | アクゾ・ノベル・エヌ・ベー | グルココルチコイド受容体アンタゴニストを用いる大うつ病性障害の治療 |
| US7326697B2 (en) * | 2002-04-29 | 2008-02-05 | Corcept Therapeutics, Inc. | Methods for increasing the therapeutic response to electroconvulsive therapy |
| CN1665515A (zh) * | 2002-07-02 | 2005-09-07 | 科塞普特治疗公司 | 治疗与干扰素α治疗相关的精神病的方法 |
| WO2004054587A1 (en) * | 2002-12-18 | 2004-07-01 | University Of Zurich | Treatment of neuro-psychiatric disorders |
| CA2514966A1 (en) * | 2003-02-04 | 2004-08-19 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of postpartum psychosis |
| US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| US20090156565A1 (en) * | 2004-12-03 | 2009-06-18 | The Children's Hospital Of Philadelphia | Composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug |
| CN100588393C (zh) * | 2004-12-15 | 2010-02-10 | 上海三合生物技术有限公司 | 赛米司酮类用于治疗抑郁症的用途 |
| US20060229505A1 (en) * | 2005-04-08 | 2006-10-12 | Mundt James C | Method and system for facilitating respondent identification with experiential scaling anchors to improve self-evaluation of clinical treatment efficacy |
| WO2007131041A2 (en) * | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
| EP1987814A1 (en) * | 2007-04-30 | 2008-11-05 | Exelgyn | Mifepristone pharmaceutical compositions and their methods of preparation |
| RU2327448C1 (ru) | 2007-05-23 | 2008-06-27 | Виктор Иванович Рощин | Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов |
| AU2008265898B2 (en) * | 2007-06-15 | 2013-11-28 | Research Triangle Institute | Androstane and pregnane steroids with potent allosteric GABA receptor chloride ionophore modulating properties |
| EP2576582B1 (en) * | 2010-05-26 | 2019-09-18 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| WO2012106514A2 (en) | 2011-02-03 | 2012-08-09 | Pop Test Cortisol Llc | System and method for diagnosis and treatment |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| AU2016226451B2 (en) * | 2015-03-02 | 2019-12-19 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonist and somatostatin analogues to treat ACTH-secreting tumors |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| EP3297728A4 (en) | 2015-05-18 | 2019-07-03 | Corcept Therapeutics Incorporated | METHOD FOR DIAGNOSIS AND ASSESSMENT OF THE TREATMENT OF THE CUSHING SYNDROME |
| CN109843183B (zh) * | 2016-10-21 | 2022-04-12 | 西铁城时计株式会社 | 检测装置 |
| KR20210153056A (ko) | 2019-03-18 | 2021-12-16 | 리네트 케이. 니만 | 인슐린 감수성 개선 방법 |
| US11903945B2 (en) | 2019-12-11 | 2024-02-20 | Corcept Therapeutics Incorporated | Methods of treating antipsychotic-induced weight gain with miricorilant |
| WO2023033900A1 (en) * | 2021-09-06 | 2023-03-09 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008588A1 (fr) * | 1992-10-20 | 1994-04-28 | Conservatoire National Des Arts Et Metiers | Compositions pharmaceutiques contenant des derives de steroides naturels 3beta hydroxyles et leur utilisation |
| EP0763541A1 (en) * | 1995-08-17 | 1997-03-19 | Akzo Nobel N.V. | 11-(Substituted phenyl)-estra-4,9-diene derivatives |
| WO1997010827A1 (fr) * | 1995-09-21 | 1997-03-27 | Hoechst Marion Roussel | Utilisation des composes antimineralocorticoides contre le syndrome de sevrage des narcotiques |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| ATE363908T1 (de) * | 1996-04-09 | 2007-06-15 | Univ Edinburgh | Verwendung von 7-alpha-substituierten steroiden zur behandlung von neuropsychiatrischen erkrankungen |
| FR2757400B1 (fr) * | 1996-12-19 | 1999-12-17 | Hoechst Marion Roussel Inc | Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs |
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1998
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- 1998-10-05 JP JP2000514650A patent/JP2001518509A/ja not_active Withdrawn
- 1998-10-05 DK DK98950911T patent/DK1023074T3/da active
- 1998-10-05 EP EP98950911A patent/EP1023074B1/en not_active Expired - Lifetime
- 1998-10-05 NZ NZ503250A patent/NZ503250A/en not_active IP Right Cessation
- 1998-10-05 CA CA002302586A patent/CA2302586C/en not_active Expired - Fee Related
- 1998-10-05 CN CNB988097923A patent/CN1187053C/zh not_active Expired - Fee Related
- 1998-10-05 KR KR1020077003769A patent/KR100840957B1/ko not_active Expired - Fee Related
- 1998-10-05 KR KR1020007003683A patent/KR100804558B1/ko not_active Expired - Fee Related
- 1998-10-05 CN CNA2006101003657A patent/CN1919199A/zh active Pending
- 1998-10-05 CN CNA200410039908XA patent/CN1528315A/zh active Pending
- 1998-10-05 DE DE69835225T patent/DE69835225T2/de not_active Expired - Lifetime
- 1998-10-05 AU AU96832/98A patent/AU747956B2/en not_active Ceased
- 1998-10-05 PT PT98950911T patent/PT1023074E/pt unknown
- 1998-10-05 WO PCT/US1998/020906 patent/WO1999017779A1/en not_active Ceased
- 1998-10-05 IL IL13546998A patent/IL135469A0/xx active IP Right Grant
- 1998-10-05 AT AT98950911T patent/ATE332696T1/de active
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1999
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2000
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- 2000-04-05 NO NO20001744A patent/NO327233B1/no not_active IP Right Cessation
- 2000-08-15 US US09/639,377 patent/US6362173B1/en not_active Expired - Lifetime
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2006
- 2006-10-05 CY CY20061101439T patent/CY1106330T1/el unknown
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2008
- 2008-10-21 JP JP2008271442A patent/JP2009051858A/ja not_active Withdrawn
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2009
- 2009-03-23 JP JP2009071039A patent/JP5180125B2/ja not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994008588A1 (fr) * | 1992-10-20 | 1994-04-28 | Conservatoire National Des Arts Et Metiers | Compositions pharmaceutiques contenant des derives de steroides naturels 3beta hydroxyles et leur utilisation |
| EP0763541A1 (en) * | 1995-08-17 | 1997-03-19 | Akzo Nobel N.V. | 11-(Substituted phenyl)-estra-4,9-diene derivatives |
| WO1997010827A1 (fr) * | 1995-09-21 | 1997-03-27 | Hoechst Marion Roussel | Utilisation des composes antimineralocorticoides contre le syndrome de sevrage des narcotiques |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001518509A (ja) | 2001-10-16 |
| KR20070032822A (ko) | 2007-03-22 |
| EP1023074B1 (en) | 2006-07-12 |
| CA2302586A1 (en) | 1999-04-15 |
| IL135469A0 (en) | 2001-05-20 |
| KR100804558B1 (ko) | 2008-02-20 |
| WO1999017779A1 (en) | 1999-04-15 |
| NO327233B1 (no) | 2009-05-18 |
| KR20010024431A (ko) | 2001-03-26 |
| PT1023074E (pt) | 2006-12-29 |
| JP2009132743A (ja) | 2009-06-18 |
| JP5180125B2 (ja) | 2013-04-10 |
| CY1106330T1 (el) | 2011-10-12 |
| NZ503250A (en) | 2001-09-28 |
| CA2302586C (en) | 2008-06-10 |
| DE69835225T2 (de) | 2007-07-05 |
| NO20001744D0 (no) | 2000-04-05 |
| ATE332696T1 (de) | 2006-08-15 |
| KR100840957B1 (ko) | 2008-06-24 |
| US6150349A (en) | 2000-11-21 |
| US6362173B1 (en) | 2002-03-26 |
| NO20001744L (no) | 2000-04-05 |
| JP2009051858A (ja) | 2009-03-12 |
| AU9683298A (en) | 1999-04-27 |
| CN1187053C (zh) | 2005-02-02 |
| CN1272788A (zh) | 2000-11-08 |
| EP1023074A1 (en) | 2000-08-02 |
| IL135469A (en) | 2007-03-08 |
| CN1919199A (zh) | 2007-02-28 |
| DE69835225D1 (de) | 2006-08-24 |
| DK1023074T3 (da) | 2006-11-06 |
| CN1528315A (zh) | 2004-09-15 |
| ES2268792T3 (es) | 2007-03-16 |
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