|
WO1998054207A1
(en)
*
|
1997-05-30 |
1998-12-03 |
Celltech Therapeutics Limited |
Anti-inflammatory tyrosine derivatives
|
|
DE69818049T2
(de)
|
1997-06-23 |
2004-07-15 |
Tanabe Seiyaku Co., Ltd. |
Inhibitoren der alpha4-beta1 vermittelten zelladhäsion
|
|
US6362341B1
(en)
|
1997-07-31 |
2002-03-26 |
Athena Neurosciences, Inc. |
Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6559127B1
(en)
|
1997-07-31 |
2003-05-06 |
Athena Neurosciences, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6939855B2
(en)
|
1997-07-31 |
2005-09-06 |
Elan Pharmaceuticals, Inc. |
Anti-inflammatory compositions and method
|
|
US6492421B1
(en)
|
1997-07-31 |
2002-12-10 |
Athena Neurosciences, Inc. |
Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6423688B1
(en)
|
1997-07-31 |
2002-07-23 |
Athena Neurosciences, Inc. |
Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6489300B1
(en)
|
1997-07-31 |
2002-12-03 |
Eugene D. Thorsett |
Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6583139B1
(en)
|
1997-07-31 |
2003-06-24 |
Eugene D. Thorsett |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US7030114B1
(en)
|
1997-07-31 |
2006-04-18 |
Elan Pharmaceuticals, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6291453B1
(en)
|
1997-07-31 |
2001-09-18 |
Athena Neurosciences, Inc. |
4-amino-phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6645939B1
(en)
|
1997-11-24 |
2003-11-11 |
Merck & Co., Inc. |
Substituted β-alanine derivatives as cell adhesion inhibitors
|
|
MY153569A
(en)
|
1998-01-20 |
2015-02-27 |
Mitsubishi Tanabe Pharma Corp |
Inhibitors of ?4 mediated cell adhesion
|
|
US6329372B1
(en)
|
1998-01-27 |
2001-12-11 |
Celltech Therapeutics Limited |
Phenylalanine derivatives
|
|
ATE273273T1
(de)
|
1998-02-26 |
2004-08-15 |
Celltech Therapeutics Ltd |
Phenylalaninderivate als inhibitoren von alpha4 integrinen
|
|
US6521626B1
(en)
|
1998-03-24 |
2003-02-18 |
Celltech R&D Limited |
Thiocarboxamide derivatives
|
|
GB9811159D0
(en)
|
1998-05-22 |
1998-07-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9811969D0
(en)
|
1998-06-03 |
1998-07-29 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6685617B1
(en)
|
1998-06-23 |
2004-02-03 |
Pharmacia & Upjohn Company |
Inhibitors of α4β1 mediated cell adhesion
|
|
GB9814414D0
(en)
|
1998-07-03 |
1998-09-02 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9821061D0
(en)
|
1998-09-28 |
1998-11-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9821222D0
(en)
|
1998-09-30 |
1998-11-25 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9825652D0
(en)
|
1998-11-23 |
1999-01-13 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9826174D0
(en)
|
1998-11-30 |
1999-01-20 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9828074D0
(en)
|
1998-12-18 |
1999-02-17 |
Glaxo Group Ltd |
Therapeutically useful compounds
|
|
CA2356969A1
(en)
*
|
1998-12-31 |
2000-07-13 |
Aventis Pharmaceuticals Inc. |
3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases
|
|
US6486193B2
(en)
|
1998-12-31 |
2002-11-26 |
Aventis Pharmaceuticals Inc. |
3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases
|
|
US6545003B1
(en)
|
1999-01-22 |
2003-04-08 |
Elan Pharmaceuticals, Inc. |
Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
KR100711840B1
(ko)
|
1999-01-22 |
2007-05-02 |
엘란 파마슈티칼스, 인크. |
Ｖｌａ-4 관련 질환 치료용 아실 유도체
|
|
US6436904B1
(en)
|
1999-01-25 |
2002-08-20 |
Elan Pharmaceuticals, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
EP1150997A1
(en)
*
|
1999-01-25 |
2001-11-07 |
Elan Pharmaceuticals, Inc. |
Compounds which inhibit leukocyte adhesion mediated by vla-4
|
|
US6407066B1
(en)
|
1999-01-26 |
2002-06-18 |
Elan Pharmaceuticals, Inc. |
Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6518283B1
(en)
|
1999-05-28 |
2003-02-11 |
Celltech R&D Limited |
Squaric acid derivatives
|
|
US6756378B2
(en)
|
1999-06-30 |
2004-06-29 |
Pharmacopeia Drug Discovery, Inc. |
VLA-4 inhibitor compounds
|
|
GB2354440A
(en)
*
|
1999-07-20 |
2001-03-28 |
Merck & Co Inc |
Aryl amides as cell adhesion inhibitors
|
|
ATE343383T1
(de)
|
1999-08-13 |
2006-11-15 |
Biogen Idec Inc |
Hemmer der zelladhäsion
|
|
US6534513B1
(en)
|
1999-09-29 |
2003-03-18 |
Celltech R&D Limited |
Phenylalkanoic acid derivatives
|
|
US6380387B1
(en)
|
1999-12-06 |
2002-04-30 |
Hoffmann-La Roche Inc. |
4-Pyrimidinyl-n-acyl-l phenylalanines
|
|
JP3824935B2
(ja)
*
|
1999-12-06 |
2006-09-20 |
エフ．ホフマン−ラ ロシュ アーゲー |
４−ピリミジニル−ｎ−アシル−ｌ−フェニルアラニン
|
|
US6388084B1
(en)
|
1999-12-06 |
2002-05-14 |
Hoffmann-La Roche Inc. |
4-pyridinyl-n-acyl-l-phenylalanines
|
|
JP2003516392A
(ja)
*
|
1999-12-06 |
2003-05-13 |
エフ．ホフマン−ラ ロシュ アーゲー |
４−ピリジニル−ｎ−アシル−ｌ−フェニルアラニン
|
|
US6455539B2
(en)
|
1999-12-23 |
2002-09-24 |
Celltech R&D Limited |
Squaric acid derivates
|
|
DE19962936A1
(de)
|
1999-12-24 |
2001-06-28 |
Bayer Ag |
Neue beta-Aminosäureverbindungen als Integrinantagonisten
|
|
AU2018301A
(en)
|
1999-12-28 |
2001-07-24 |
Pfizer Products Inc. |
Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
|
|
ATE375330T1
(de)
|
2000-04-17 |
2007-10-15 |
Ucb Pharma Sa |
Enamin-derivate als zell-adhäsionsmoleküle
|
|
US6545013B2
(en)
|
2000-05-30 |
2003-04-08 |
Celltech R&D Limited |
2,7-naphthyridine derivatives
|
|
US6403608B1
(en)
|
2000-05-30 |
2002-06-11 |
Celltech R&D, Ltd. |
3-Substituted isoquinolin-1-yl derivatives
|
|
US6960597B2
(en)
*
|
2000-06-30 |
2005-11-01 |
Orth-Mcneil Pharmaceutical, Inc. |
Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists
|
|
AU2001267753A1
(en)
|
2000-07-07 |
2002-01-21 |
Celltech R And D Limited |
Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists
|
|
JP2004505110A
(ja)
|
2000-08-02 |
2004-02-19 |
セルテック アール アンド ディ リミテッド |
３位置換イソキノリン−１−イル誘導体
|
|
MY129000A
(en)
|
2000-08-31 |
2007-03-30 |
Tanabe Seiyaku Co |
INHIBITORS OF a4 MEDIATED CELL ADHESION
|
|
YU23503A
(sh)
*
|
2000-09-29 |
2006-03-03 |
Neurogen Corporation |
Mali molekuli kao modulatori receptora c5a visokog afiniteta
|
|
AR038957A1
(es)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
|
SI1485127T1
(sl)
|
2002-02-25 |
2011-09-30 |
Elan Pharm Inc |
Dajanje aktivne snovi za zdravljenje vnetja
|
|
TWI281470B
(en)
|
2002-05-24 |
2007-05-21 |
Elan Pharm Inc |
Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
|
|
TW200307671A
(en)
|
2002-05-24 |
2003-12-16 |
Elan Pharm Inc |
Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
|
|
CN1703395A
(zh)
|
2002-08-09 |
2005-11-30 |
特兰斯泰克制药公司 |
芳基和杂芳基化合物以及调节凝血的方法
|
|
WO2004041279A1
(en)
|
2002-10-30 |
2004-05-21 |
Merck & Co., Inc. |
Gamma-aminoamide modulators of chemokine receptor activity
|
|
AU2004207536B2
(en)
|
2003-01-24 |
2010-05-20 |
Elan Pharmaceuticals Inc. |
Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
|
|
WO2005014532A1
(en)
|
2003-08-08 |
2005-02-17 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions and methods of use
|
|
US7208601B2
(en)
|
2003-08-08 |
2007-04-24 |
Mjalli Adnan M M |
Aryl and heteroaryl compounds, compositions, and methods of use
|
|
JP2007501844A
(ja)
|
2003-08-08 |
2007-02-01 |
トランス テック ファーマ，インコーポレイテッド |
アリール及びヘテロアリール化合物、組成物並びに使用方法
|
|
GEP20094680B
(en)
|
2004-04-13 |
2009-05-10 |
Incyte Corp |
Piperazinylpiperidine derivatives as chemokine receptor antagonists
|
|
FR2869904B1
(fr)
*
|
2004-05-07 |
2006-07-28 |
Fournier S A Sa Lab |
Modulateurs des recepteurs lxr
|
|
CN101035563B
(zh)
|
2004-07-08 |
2012-03-28 |
艾伦药物公司 |
包括聚合物部分的多价vla-4拮抗剂
|
|
US7196112B2
(en)
|
2004-07-16 |
2007-03-27 |
Biogen Idec Ma Inc. |
Cell adhesion inhibitors
|
|
DE602006020754D1
(de)
|
2005-09-29 |
2011-04-28 |
Elan Pharm Inc |
Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren
|
|
AU2006297220B8
(en)
|
2005-09-29 |
2013-01-31 |
Elan Pharmaceuticals, Inc. |
Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
MEP1008A
(xx)
|
2005-12-21 |
2010-02-10 |
Incyte Corp |
3-aminociklopentankarboksamidi kao modulatori receptora hemokina
|
|
TWI389904B
(zh)
|
2006-02-27 |
2013-03-21 |
Elan Pharm Inc |
抑制由ｖｌａ-４所調節的白血球黏附之嘧啶磺醯胺化合物
|
|
TW200811164A
(en)
*
|
2006-05-12 |
2008-03-01 |
Jerini Ag |
New heterocyclic compounds for the inhibition of integrins and use thereof
|
|
US20100150915A1
(en)
|
2007-02-20 |
2010-06-17 |
Stewart Edward J |
Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
|
|
KR20110008086A
(ko)
|
2008-04-11 |
2011-01-25 |
메리맥 파마슈티컬즈, 인크. |
인간 혈청 알부민 링커 및 그 콘쥬게이트
|
|
PT2370442E
(pt)
|
2008-11-26 |
2013-06-27 |
Pfizer |
3-aminociclopentanocarboxamidas como moduladores de receptor de quimiocina
|
|
CN102307875A
(zh)
|
2009-02-09 |
2012-01-04 |
苏伯俭股份有限公司 |
吡咯并嘧啶基axl激酶抑制剂
|
|
MA33364B1
(fr)
|
2009-05-28 |
2012-06-01 |
Novartis Ag |
Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine
|
|
MX2011012628A
(es)
|
2009-05-28 |
2011-12-14 |
Novartis Ag |
Derivados amino-propionicos sustituidos como inhibidores de neprilisina.
|
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
|
AU2014216417B2
(en)
|
2013-02-14 |
2016-05-12 |
Novartis Ag |
Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy
|
|
HRP20180958T1
(hr)
|
2013-02-14 |
2018-07-27 |
Novartis Ag |
Supstituirani derivati bisfenolbutanfosfonske kiseline kao inhibitori za nep (neutralnu endopeptidazu)
|
|
EP3116910A1
(en)
|
2014-03-13 |
2017-01-18 |
Prothena Biosciences Limited |
Combination treatment for multiple sclerosis
|
|
WO2018085578A1
(en)
*
|
2016-11-02 |
2018-05-11 |
Saint Louis University |
Integrin inhibitors in combination with an agent which interacts with a chemokine receptor
|
|
US11179383B2
(en)
|
2018-10-30 |
2021-11-23 |
Gilead Sciences, Inc. |
Compounds for inhibition of α4β7 integrin
|
|
WO2020092394A1
(en)
|
2018-10-30 |
2020-05-07 |
Gilead Sciences, Inc. |
Imidazopyridine derivatives as alpha4beta7 integrin inhibitors
|
|
JP7189368B2
(ja)
|
2018-10-30 |
2022-12-13 |
ギリアード サイエンシーズ， インコーポレイテッド |
アルファ４ベータ７インテグリンの阻害のための化合物
|
|
KR102630416B1
(ko)
|
2018-10-30 |
2024-02-01 |
길리애드 사이언시즈, 인코포레이티드 |
알파4베타7 인테그린 억제제로서의 퀴놀린 유도체
|
|
CN114222730B
(zh)
|
2019-08-14 |
2024-09-10 |
吉利德科学公司 |
用于抑制α4β7整合素的化合物
|
|
AU2021289665A1
(en)
|
2020-06-10 |
2022-12-15 |
Aligos Therapeutics, Inc. |
Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
|
|
IL309732A
(en)
|
2021-07-09 |
2024-02-01 |
Aligos Therapeutics Inc |
Antiviral compounds
|
|
WO2023043816A1
(en)
|
2021-09-17 |
2023-03-23 |
Aligos Therapeutics, Inc. |
Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
|