JP2001516583A5 - - Google Patents
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- Publication number
- JP2001516583A5 JP2001516583A5 JP2000511872A JP2000511872A JP2001516583A5 JP 2001516583 A5 JP2001516583 A5 JP 2001516583A5 JP 2000511872 A JP2000511872 A JP 2000511872A JP 2000511872 A JP2000511872 A JP 2000511872A JP 2001516583 A5 JP2001516583 A5 JP 2001516583A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- rsv
- polypeptide
- lysine
- vertebrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229960005486 vaccine Drugs 0.000 description 27
- 108091006027 G proteins Proteins 0.000 description 26
- 102000030782 GTP binding Human genes 0.000 description 26
- 108091000058 GTP-Binding Proteins 0.000 description 26
- 229920001184 polypeptide Polymers 0.000 description 26
- 102000004196 processed proteins & peptides Human genes 0.000 description 26
- 108090000765 processed proteins & peptides Proteins 0.000 description 26
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 25
- 230000002163 immunogen Effects 0.000 description 22
- 150000001413 amino acids Chemical class 0.000 description 20
- 150000007523 nucleic acids Chemical class 0.000 description 16
- 108020004707 nucleic acids Proteins 0.000 description 15
- 102000039446 nucleic acids Human genes 0.000 description 15
- 201000010099 disease Diseases 0.000 description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 13
- 208000015181 infectious disease Diseases 0.000 description 10
- 230000004048 modification Effects 0.000 description 9
- 238000012986 modification Methods 0.000 description 9
- 230000005847 immunogenicity Effects 0.000 description 8
- 230000002238 attenuated effect Effects 0.000 description 6
- 239000004473 Threonine Substances 0.000 description 5
- 230000001939 inductive effect Effects 0.000 description 4
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 description 3
- 102000000743 Interleukin-5 Human genes 0.000 description 3
- 108010002616 Interleukin-5 Proteins 0.000 description 3
- 230000004075 alteration Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000037452 priming Effects 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 206010003757 Atypical pneumonia Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 229940031567 attenuated vaccine Drugs 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 206010014950 Eosinophilia Diseases 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000710959 Venezuelan equine encephalitis virus Species 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5968497P | 1997-09-19 | 1997-09-19 | |
| US60/059,684 | 1997-09-19 | ||
| US8486398P | 1998-05-08 | 1998-05-08 | |
| US60/084,863 | 1998-05-08 | ||
| PCT/US1998/019656 WO1999014334A1 (en) | 1997-09-19 | 1998-09-17 | Peptides derived from the attachment (g) protein of respiratory syncytial virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001516583A JP2001516583A (ja) | 2001-10-02 |
| JP2001516583A5 true JP2001516583A5 (enExample) | 2006-01-05 |
Family
ID=26739056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000511872A Withdrawn JP2001516583A (ja) | 1997-09-19 | 1998-09-17 | Ｒｓウイルスの付着（ｇ）タンパク質由来のペプチド |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1015595B1 (enExample) |
| JP (1) | JP2001516583A (enExample) |
| KR (1) | KR100550132B1 (enExample) |
| CN (1) | CN1259422C (enExample) |
| AT (1) | ATE287957T1 (enExample) |
| AU (1) | AU751022B2 (enExample) |
| BR (1) | BR9812240A (enExample) |
| CA (1) | CA2302833C (enExample) |
| CY (1) | CY1105010T1 (enExample) |
| DE (1) | DE69828801T2 (enExample) |
| ES (1) | ES2236946T3 (enExample) |
| PT (1) | PT1015595E (enExample) |
| WO (1) | WO1999014334A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1334119B2 (en) | 2000-10-18 | 2018-11-28 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Compositions and methods for modulating rsv infection and immunity |
| AUPR520201A0 (en) * | 2001-05-23 | 2001-06-14 | Commonwealth Scientific And Industrial Research Organisation | Antiviral compounds |
| NL1019228C1 (nl) | 2001-10-25 | 2003-04-28 | Duynstee Holding B V | Verbeterd gecombineerd ophang- en verlichtingssysteem voor bijvoorbeeld schilderijen e.d. |
| US6667327B2 (en) | 2002-02-04 | 2003-12-23 | Hoffmann-La Roche Inc. | Pyridine amido derivatives |
| DE10219219A1 (de) | 2002-04-29 | 2003-11-06 | Tampoflex Gmbh | Druckanlage |
| WO2004092207A2 (en) * | 2003-04-16 | 2004-10-28 | Algonomics N.V. | Respiratory syncytial virus (rsv) peptides |
| US7368537B2 (en) * | 2003-07-15 | 2008-05-06 | Id Biomedical Corporation Of Quebec | Subunit vaccine against respiratory syncytial virus infection |
| RU2006117366A (ru) | 2003-10-23 | 2007-12-10 | Ф.Хоффманн-Ля Рош Аг (Ch) | Производные бензазепина в качестве ингибиторов мао-в |
| US7666433B2 (en) * | 2004-06-30 | 2010-02-23 | Wyeth Holdings Corporation | Recombinant RSV strains with altered G protein |
| EP2181121A4 (en) * | 2007-03-21 | 2012-07-11 | Id Biomedical Corp Quebec | CHIMÄRE ANTIGENE |
| US8563002B2 (en) | 2007-12-24 | 2013-10-22 | Glaxosmithkline Biologicals, S.A. | Recombinant RSV antigens |
| SG176807A1 (en) | 2009-06-24 | 2012-01-30 | Id Biomedical Corp Quebec | Vaccine |
| PL2445526T3 (pl) | 2009-06-24 | 2017-08-31 | Glaxosmithkline Biologicals S.A. | Rekombinowane antygeny rsv |
| EP4183412B1 (en) | 2009-07-15 | 2024-08-14 | GlaxoSmithKline Biologicals SA | Rsv f protein compositions and methods for making same |
| EP2453903B1 (en) * | 2009-07-17 | 2016-08-17 | Industry Academic Cooperation Foundation, Hallym University | Immunostimulatory compositions comprising liposome-encapsulated oligonucleotides and epitopes |
| US8846056B2 (en) | 2009-08-04 | 2014-09-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control | Anti-RSV immunogens and methods of immunization |
| RS56748B1 (sr) | 2011-05-13 | 2018-03-30 | Glaxosmithkline Biologicals Sa | Pre-fuzioni rsv f antigeni |
| EP3956351A1 (en) * | 2019-04-18 | 2022-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Biological and synthetic molecules inhibiting respiratory syncytial virus infection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2726577B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Procede d'obtention d'un peptide derive du virus respiratoire syncitial, polypeptide et bacterie l'exprimant, et leurs applications a titre de medicament |
| AU722494C (en) * | 1996-06-05 | 2007-03-29 | Commonwealth Scientific And Industrial Research Organisation | Viral peptides with structural homology to protein G of respiratory syncytial virus |
| AUPO026596A0 (en) * | 1996-06-05 | 1996-06-27 | Biomolecular Research Institute Limited | Viral peptide |
-
1998
- 1998-09-17 CA CA002302833A patent/CA2302833C/en not_active Expired - Fee Related
- 1998-09-17 WO PCT/US1998/019656 patent/WO1999014334A1/en not_active Ceased
- 1998-09-17 PT PT98949392T patent/PT1015595E/pt unknown
- 1998-09-17 AU AU95725/98A patent/AU751022B2/en not_active Ceased
- 1998-09-17 BR BR9812240-1A patent/BR9812240A/pt not_active Application Discontinuation
- 1998-09-17 AT AT98949392T patent/ATE287957T1/de not_active IP Right Cessation
- 1998-09-17 ES ES98949392T patent/ES2236946T3/es not_active Expired - Lifetime
- 1998-09-17 DE DE69828801T patent/DE69828801T2/de not_active Expired - Fee Related
- 1998-09-17 KR KR1020007002861A patent/KR100550132B1/ko not_active Expired - Fee Related
- 1998-09-17 JP JP2000511872A patent/JP2001516583A/ja not_active Withdrawn
- 1998-09-17 EP EP98949392A patent/EP1015595B1/en not_active Expired - Lifetime
- 1998-09-17 CN CNB988104911A patent/CN1259422C/zh not_active Expired - Fee Related
-
2005
- 2005-02-24 CY CY20051100274T patent/CY1105010T1/el unknown
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