JP2001514879A5 - - Google Patents

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Publication number
JP2001514879A5
JP2001514879A5 JP2000509807A JP2000509807A JP2001514879A5 JP 2001514879 A5 JP2001514879 A5 JP 2001514879A5 JP 2000509807 A JP2000509807 A JP 2000509807A JP 2000509807 A JP2000509807 A JP 2000509807A JP 2001514879 A5 JP2001514879 A5 JP 2001514879A5
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JP
Japan
Prior art keywords
vanilloid
receptor
polypeptide
compound
host cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000509807A
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English (en)
Japanese (ja)
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JP2001514879A (ja
JP4444493B2 (ja
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Priority claimed from PCT/US1998/017466 external-priority patent/WO1999009140A1/en
Publication of JP2001514879A publication Critical patent/JP2001514879A/ja
Publication of JP2001514879A5 publication Critical patent/JP2001514879A5/ja
Application granted granted Critical
Publication of JP4444493B2 publication Critical patent/JP4444493B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2000509807A 1997-08-20 1998-08-20 カプサイシン受容体およびカプサイシン受容体関連ポリペプチドをコードする核酸配列ならびにその使用 Expired - Lifetime JP4444493B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US91546197A 1997-08-20 1997-08-20
US08/915,461 1997-08-20
US7215198P 1998-01-22 1998-01-22
US60/072,151 1998-01-22
PCT/US1998/017466 WO1999009140A1 (en) 1997-08-20 1998-08-20 Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof

Publications (3)

Publication Number Publication Date
JP2001514879A JP2001514879A (ja) 2001-09-18
JP2001514879A5 true JP2001514879A5 (https=) 2006-02-16
JP4444493B2 JP4444493B2 (ja) 2010-03-31

Family

ID=26753050

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000509807A Expired - Lifetime JP4444493B2 (ja) 1997-08-20 1998-08-20 カプサイシン受容体およびカプサイシン受容体関連ポリペプチドをコードする核酸配列ならびにその使用

Country Status (8)

Country Link
US (3) US6335180B1 (https=)
EP (1) EP1009804B1 (https=)
JP (1) JP4444493B2 (https=)
AT (1) ATE253111T1 (https=)
AU (1) AU742391B2 (https=)
CA (1) CA2298540A1 (https=)
DE (1) DE69819345T2 (https=)
WO (1) WO1999009140A1 (https=)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444440B1 (en) 1997-03-07 2002-09-03 Human Genome Sciences, Inc. Vanilloid receptor-2
WO1999009140A1 (en) 1997-08-20 1999-02-25 The Regents Of The University Of California Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
CA2309903C (en) * 1998-01-22 2012-03-27 The Regents Of The University Of California Nucleic acid sequences encoding capsaicin receptor
WO1999037765A1 (en) * 1998-01-27 1999-07-29 Smithkline Beecham Plc Human vanilloid receptor homologues
EP0943683A1 (en) 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP0953638A1 (en) * 1998-03-11 1999-11-03 Synthelabo Human vanilloid receptor-like cation channel
US6906178B2 (en) 1998-08-11 2005-06-14 Human Genome Sciences, Inc. Vanilloid receptor-2
EP1131433A1 (en) * 1998-11-13 2001-09-12 Millennium Pharmaceuticals, Inc. Members of the capsaicin/vanilloid receptor family of proteins and uses thereof
US7063951B1 (en) 1998-11-13 2006-06-20 Millennium Pharmaceuticals, Inc. Members of the capsaicin/vanilloid receptor family of proteins and uses thereof
GB9826359D0 (en) * 1998-12-01 1999-01-27 Glaxo Group Ltd Novel receptors
GB9827016D0 (en) 1998-12-08 1999-02-03 Merck Sharp & Dohme Receptor protein
GB9907097D0 (en) * 1999-03-26 1999-05-19 Novartis Ag Organic compounds
CA2370570A1 (en) * 1999-04-15 2000-10-26 Adrienne Dubin Dna encoding the human vanilloid receptor vr1
US6421613B1 (en) * 1999-07-09 2002-07-16 Pioneer Hi-Bred International, Inc. Data processing of the maize prolifera genetic sequence
US6482611B1 (en) 1999-09-23 2002-11-19 Neurogen Corporation Human capsaicin receptor and uses thereof
US6455278B1 (en) * 2000-02-08 2002-09-24 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding human vanilloid receptor VR3
HUP0300489A3 (en) * 2000-02-25 2006-06-28 Daiichi Seiyaku Co Novel protein and gene encoding the same
DE10043674A1 (de) * 2000-09-02 2002-03-21 Gruenenthal Gmbh Antisense Oligonukleotide
AU2001295531A1 (en) * 2000-09-02 2002-03-13 Grünenthal GmbH Antisense oligonucleotides against vanilloid receptor 1
US7112685B2 (en) 2000-10-10 2006-09-26 Ortho-Mcneil Pharmaceutical, Inc. Labeled resiniferatoxin derivatives
JP2004511803A (ja) 2000-10-16 2004-04-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド バニロイド受容体についての改良リガンド結合アッセイ
US20030027164A1 (en) * 2000-12-01 2003-02-06 Gaughan Glen T. Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain
US20030171275A1 (en) * 2000-12-20 2003-09-11 Baughn Mariah R. Transporters and ion channels
GB0128161D0 (en) * 2001-11-23 2002-01-16 Merck Sharp & Dohme Receptor protein
US7071335B2 (en) 2002-02-01 2006-07-04 Euro-Celtique S.A. 2-pyridinyl-1-piperazine therapeutic agents useful for treating pain
AU2002318168B2 (en) 2002-02-25 2007-12-13 Vaxiion Therapeutics, Llc Minicell compositions and methods
US6974818B2 (en) * 2002-03-01 2005-12-13 Euro-Celtique S.A. 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
EP1497328A2 (en) * 2002-04-16 2005-01-19 Bayer HealthCare AG Regulation of human transient receptor potential channel
EP1532452A4 (en) * 2002-05-31 2006-11-29 Sloan Kettering Inst Cancer HETEROLOGY STIMULUS-CONTROLLED ION CHANNELS AND METHOD FOR USE THEREOF
AR041191A1 (es) 2002-08-08 2005-05-04 Amgen Inc Ligandos del receptor vanilloide y su uso en tratamientos
AU2003259846A1 (en) * 2002-08-16 2004-03-03 The General Hospital Corporation Non-invasive functional imaging of peripheral nervous system activation in humans and animals
US7582635B2 (en) 2002-12-24 2009-09-01 Purdue Pharma, L.P. Therapeutic agents useful for treating pain
US20050085652A1 (en) * 2003-04-08 2005-04-21 Algorx Pharmaceuticals, Inc. Preparation and purification of synthetic capsaicin
TWI287010B (en) * 2003-06-12 2007-09-21 Euro Celtique Sa Therapeutic agents useful for treating pain
WO2005006881A2 (en) * 2003-07-09 2005-01-27 Virginia Commonwealth University Salt taste modification
DE602004017316D1 (de) 2003-07-24 2008-12-04 Euro Celtique Sa Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen
GEP20094676B (en) * 2003-07-24 2009-05-10 Euro Celtique Sa Piperidine compounds and pharmaceutical compositions containing them
EP1867644B1 (en) 2003-07-24 2009-05-20 Euro-Celtique S.A. Heteroaryl-tetrahydropiperidyl compounds useful for treating or preventing pain
WO2005012287A1 (en) * 2003-08-01 2005-02-10 Euro-Celtique S.A. Therapeutic agents useful for treating pain
SI1664016T1 (sl) * 2003-09-22 2009-04-30 Euro Celtique Sa Terapevtska sredstva, uporabna za zdravljenje bolečine
PL1664041T3 (pl) * 2003-09-22 2008-12-31 Euro Celtique Sa Przydatne do leczenia bólu związki fenylowo-karboksyamidowe
PL1727801T3 (pl) * 2003-12-30 2009-08-31 Euro Celtique Sa Piperazyny użyteczne do leczenia bólu
US20070159522A1 (en) * 2004-02-20 2007-07-12 Harmut Neven Image-based contextual advertisement method and branded barcodes
US7751805B2 (en) * 2004-02-20 2010-07-06 Google Inc. Mobile image-based information retrieval system
US20050266435A1 (en) * 2004-03-09 2005-12-01 David Hackos VR1 receptors and uses thereof
GB0412769D0 (en) 2004-06-08 2004-07-07 Novartis Ag Organic compounds
AU2005309586A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
EP2500429A3 (en) * 2005-05-31 2015-10-28 Devgen N.V. RNAi for the control of insects and arachnids
WO2007149559A2 (en) 2006-06-22 2007-12-27 Board Of Regents Of The University Of Nebraska Magnetically coupleable robotic devices and related methods
US8679096B2 (en) 2007-06-21 2014-03-25 Board Of Regents Of The University Of Nebraska Multifunctional operational component for robotic devices
US20080153845A1 (en) * 2006-10-27 2008-06-26 Redpoint Bio Corporation Trpv1 antagonists and uses thereof
MX2009011601A (es) 2007-04-27 2009-11-10 Purdue Pharma Lp Agentes terapeuticos utiles para tratar el dolor.
CA2685266C (en) * 2007-04-27 2014-01-28 Purdue Pharma L.P. Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal
EP2170564A4 (en) 2007-07-12 2015-10-07 Univ Nebraska ACTUATING PROCESSES AND SYSTEMS IN ROBOTIC EQUIPMENT
JP2010536435A (ja) 2007-08-15 2010-12-02 ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ 医療用膨張、取り付けおよび送達装置、ならびに関連する方法
WO2009114143A1 (en) * 2008-03-12 2009-09-17 Brown University Treatment and prophylaxis of epilepsy and febrile seizures
US8546388B2 (en) * 2008-10-24 2013-10-01 Purdue Pharma L.P. Heterocyclic TRPV1 receptor ligands
US8703962B2 (en) * 2008-10-24 2014-04-22 Purdue Pharma L.P. Monocyclic compounds and their use as TRPV1 ligands
US8759362B2 (en) * 2008-10-24 2014-06-24 Purdue Pharma L.P. Bicycloheteroaryl compounds and their use as TRPV1 ligands
WO2010124200A2 (en) * 2009-04-23 2010-10-28 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for cancer
EP2449112A1 (en) 2009-07-01 2012-05-09 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (scid)
WO2011014721A2 (en) * 2009-07-30 2011-02-03 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for pharmacokinetics
WO2011017518A2 (en) * 2009-08-05 2011-02-10 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for drug metabolism
WO2011022634A2 (en) * 2009-08-20 2011-02-24 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for pain
WO2013048595A1 (en) 2011-06-10 2013-04-04 Board Of Regents Of The University Of Nebraska Methods, systems, and devices relating to surgical end effectors
PE20141531A1 (es) 2011-06-22 2014-10-23 Purdue Pharma Lp Antagonistas de trpv1 que incluyen sustituyentes dihidroxi y sus usos
EP3588217A1 (en) 2011-07-11 2020-01-01 Board of Regents of the University of Nebraska Robotic surgical devices, systems and related methods
AU2012293417A1 (en) 2011-08-10 2013-05-02 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
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EP2806941B1 (en) 2012-01-10 2021-10-27 Board of Regents of the University of Nebraska Systems and devices for surgical access and insertion
WO2014011238A2 (en) 2012-05-01 2014-01-16 Board Of Regents Of The University Of Nebraska Single site robotic device and related systems and methods
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US9770305B2 (en) 2012-08-08 2017-09-26 Board Of Regents Of The University Of Nebraska Robotic surgical devices, systems, and related methods
WO2014152418A1 (en) 2013-03-14 2014-09-25 Board Of Regents Of The University Of Nebraska Methods, systems, and devices relating to force control surgical systems
US9743987B2 (en) 2013-03-14 2017-08-29 Board Of Regents Of The University Of Nebraska Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers
WO2014144220A1 (en) 2013-03-15 2014-09-18 Board Of Regents Of The University Of Nebraska Robotic surgical devices, systems, and related methdos
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EP3457951B1 (en) 2016-05-18 2024-03-06 Virtual Incision Corporation Robotic surgical devices and systems
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GB201918103D0 (en) 2019-12-10 2020-01-22 Oblique Therapeutics Ab Epitopes and antibodies
CA3186863A1 (en) 2020-07-06 2022-01-13 Virtual Incision Corporation Surgical robot positioning system and related devices and methods

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5074977A (en) 1987-05-05 1991-12-24 The Washington Technology Center Digital biosensors and method of using same
US5234566A (en) 1988-08-18 1993-08-10 Australian Membrane And Biotechnology Research Institute Ltd. Sensitivity and selectivity of ion channel biosensor membranes
ES2102364T3 (es) 1989-01-27 1997-08-01 Au Membrane & Biotech Res Inst Membranas receptoras y control del paso a su traves por medio de ionoforos.
US5491097A (en) 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5328847A (en) 1990-02-20 1994-07-12 Case George D Thin membrane sensor with biochemical switch
US5232684A (en) * 1990-06-29 1993-08-03 The United States Of America As Represented By The Department Of Health And Human Services Labelled resiniferatoxin, compositions thereof, and methods for using the same
WO1999009140A1 (en) 1997-08-20 1999-02-25 The Regents Of The University Of California Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
WO1999037765A1 (en) 1998-01-27 1999-07-29 Smithkline Beecham Plc Human vanilloid receptor homologues
EP0943683A1 (en) 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP0953638A1 (en) 1998-03-11 1999-11-03 Synthelabo Human vanilloid receptor-like cation channel
EP1131433A1 (en) 1998-11-13 2001-09-12 Millennium Pharmaceuticals, Inc. Members of the capsaicin/vanilloid receptor family of proteins and uses thereof
GB9826359D0 (en) * 1998-12-01 1999-01-27 Glaxo Group Ltd Novel receptors
CA2370570A1 (en) 1999-04-15 2000-10-26 Adrienne Dubin Dna encoding the human vanilloid receptor vr1
EP1144628A3 (en) 1999-11-12 2002-02-27 Abbott Laboratories Human vanilloid receptor gene
WO2001068857A2 (en) 2000-03-15 2001-09-20 Millennium Pharmaceuticals, Inc. 18615 and 48003, human ion channels and uses therefor
JP3501775B2 (ja) 2000-05-31 2004-03-02 ファイザー株式会社 ヒトバニロイド受容体様タンパク質

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