JP2001514663A - アルツハイマー病を処置または予防するための方法 - Google Patents
アルツハイマー病を処置または予防するための方法Info
- Publication number
- JP2001514663A JP2001514663A JP53974498A JP53974498A JP2001514663A JP 2001514663 A JP2001514663 A JP 2001514663A JP 53974498 A JP53974498 A JP 53974498A JP 53974498 A JP53974498 A JP 53974498A JP 2001514663 A JP2001514663 A JP 2001514663A
- Authority
- JP
- Japan
- Prior art keywords
- insulin
- food
- disease
- agent
- per day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3960797P | 1997-03-12 | 1997-03-12 | |
| US60/039,607 | 1997-03-12 | ||
| PCT/US1998/004731 WO1998039967A1 (en) | 1997-03-12 | 1998-03-12 | A method for treating or preventing alzheimer's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009148356A Division JP2009280586A (ja) | 1997-03-12 | 2009-06-23 | アルツハイマー病を処置または予防するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001514663A true JP2001514663A (ja) | 2001-09-11 |
| JP2001514663A5 JP2001514663A5 (https=) | 2005-11-10 |
Family
ID=21906390
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53974498A Pending JP2001514663A (ja) | 1997-03-12 | 1998-03-12 | アルツハイマー病を処置または予防するための方法 |
| JP2009148356A Pending JP2009280586A (ja) | 1997-03-12 | 2009-06-23 | アルツハイマー病を処置または予防するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009148356A Pending JP2009280586A (ja) | 1997-03-12 | 2009-06-23 | アルツハイマー病を処置または予防するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7300927B2 (https=) |
| EP (1) | EP1006794B1 (https=) |
| JP (2) | JP2001514663A (https=) |
| CA (1) | CA2323889A1 (https=) |
| DE (1) | DE69838789T2 (https=) |
| WO (1) | WO1998039967A1 (https=) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004043443A (ja) * | 2002-05-14 | 2004-02-12 | Kumamoto Technology & Industry Foundation | アミロイドーシスの予防及び治療のための医薬 |
| JP2012500004A (ja) * | 2008-08-12 | 2012-01-05 | ジンファンデル ファーマシューティカルズ インコーポレイテッド | 疾患危険因子を同定する方法 |
| WO2019004321A1 (ja) * | 2017-06-28 | 2019-01-03 | 国立大学法人京都大学 | アルツハイマー病の予防及び/又は治療剤 |
| US11021751B2 (en) | 2008-08-12 | 2021-06-01 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
Families Citing this family (28)
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| EP1006794B1 (en) * | 1997-03-12 | 2007-11-28 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
| CA2311356C (en) * | 1998-01-28 | 2004-07-13 | Warner-Lambert Company | Method for treating alzheimer's disease |
| US6191154B1 (en) * | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
| WO2000043006A1 (en) * | 1999-01-19 | 2000-07-27 | Sankyo Company, Limited | Inhibitor for nerve cell death due to glutamic acid cytotoxicity |
| WO2007115282A2 (en) * | 2006-04-03 | 2007-10-11 | Accera, Inc. | Use of ketogenic compounds for treatment of age-associated memory impairment |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| AU2001257451A1 (en) | 2000-05-01 | 2001-11-12 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
| US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
| US6770797B2 (en) | 2001-06-01 | 2004-08-03 | Rhode Island Hospital | Non-Transgenic nonhuman model for Alzheimer's Disease using a AD7c-NTP nucleic acid |
| ATE476188T1 (de) * | 2002-05-14 | 2010-08-15 | Nipro Corp | Medikament zur prävention und behandlung von familiärer amyloid polyneuropathie |
| AU2003274052A1 (en) * | 2002-11-12 | 2004-06-03 | L'oreal | Use of cellulose microbeads to make the skin matt |
| US20060189545A1 (en) * | 2003-03-06 | 2006-08-24 | Henderson Samuel T | Novel chemical entities and methods for their use in treatment of metabolic disorders |
| US20090088367A1 (en) * | 2004-05-10 | 2009-04-02 | Burnham Institute For Medical Research | Treatment of Insulin Resistance/Metabolic Syndrome to Alleviate the Risks of Dementia |
| US7833513B2 (en) * | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
| US8114847B2 (en) | 2005-03-16 | 2012-02-14 | Case Western Reserve University | Selective inhibitors of translesion DNA replication |
| WO2008147454A1 (en) | 2006-11-16 | 2008-12-04 | Case Western Reserve University | Selective inhibitors of translesion dna replication |
| US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
| WO2007001883A2 (en) * | 2005-06-20 | 2007-01-04 | Accera, Inc. | Method to reduce oxidative damage and improve mitochondrial efficiency |
| CA2853992C (en) | 2007-07-31 | 2020-06-23 | Cerecin Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
| US20090216178A1 (en) * | 2008-02-26 | 2009-08-27 | Lee Susan J | Method And Apparatus For Preventing Localized Stasis Of Cerebrospinal Fluid |
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| EP2448412B1 (en) * | 2009-07-01 | 2019-05-01 | JDS Therapeutics, LLC | Chromium complexes as enhancers of brain glucose transporters |
| AU2012205798B2 (en) | 2011-01-10 | 2016-02-25 | Takeda Pharmaceutical Company Limited | Methods and drug products for treating Alzheimer's disease |
| US9988680B2 (en) | 2011-09-01 | 2018-06-05 | Case Western Reserve University | Non-natural nucleosides as theranostic agents |
| US9821173B2 (en) | 2013-02-08 | 2017-11-21 | Case Western Reserve University | Anti-cancer agents and methods of use |
| KR101642042B1 (ko) * | 2013-10-24 | 2016-07-22 | 건국대학교 글로컬산학협력단 | 티아졸리딘디온의 p35 및 p25 활성 변화에 대한 용도 |
| CA3014308A1 (en) | 2016-02-11 | 2017-08-17 | Nutrition 21, Llc | Chromium containing compositions for improving health and fitness |
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1998
- 1998-03-12 EP EP98909105A patent/EP1006794B1/en not_active Expired - Lifetime
- 1998-03-12 CA CA002323889A patent/CA2323889A1/en not_active Abandoned
- 1998-03-12 DE DE69838789T patent/DE69838789T2/de not_active Expired - Lifetime
- 1998-03-12 JP JP53974498A patent/JP2001514663A/ja active Pending
- 1998-03-12 WO PCT/US1998/004731 patent/WO1998039967A1/en not_active Ceased
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2003
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2004
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-
2009
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- 2009-07-20 US US12/505,868 patent/US20090280192A1/en not_active Abandoned
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| JP2004043443A (ja) * | 2002-05-14 | 2004-02-12 | Kumamoto Technology & Industry Foundation | アミロイドーシスの予防及び治療のための医薬 |
| JP2012500004A (ja) * | 2008-08-12 | 2012-01-05 | ジンファンデル ファーマシューティカルズ インコーポレイテッド | 疾患危険因子を同定する方法 |
| JP2016047058A (ja) * | 2008-08-12 | 2016-04-07 | ジンファンデル ファーマシューティカルズ インコーポレイテッド | 疾患危険因子を同定する方法 |
| JP2018075005A (ja) * | 2008-08-12 | 2018-05-17 | ジンファンデル ファーマシューティカルズ インコーポレイテッド | 疾患危険因子を同定する方法 |
| US10865449B2 (en) | 2008-08-12 | 2020-12-15 | Zinfandel Pharmaceuticals, Inc. | Method of identifying disease risk factors |
| US11021751B2 (en) | 2008-08-12 | 2021-06-01 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| WO2019004321A1 (ja) * | 2017-06-28 | 2019-01-03 | 国立大学法人京都大学 | アルツハイマー病の予防及び/又は治療剤 |
| JPWO2019004321A1 (ja) * | 2017-06-28 | 2020-04-30 | 国立大学法人京都大学 | アルツハイマー病の予防及び/又は治療剤 |
| US11554116B2 (en) | 2017-06-28 | 2023-01-17 | Kyoto University | Agent for preventing and/or treating alzheimer's disease |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1006794A4 (en) | 2004-07-07 |
| JP2009280586A (ja) | 2009-12-03 |
| US20040060077A1 (en) | 2004-03-25 |
| EP1006794A1 (en) | 2000-06-14 |
| DE69838789T2 (de) | 2008-10-30 |
| WO1998039967A1 (en) | 1998-09-17 |
| US7300927B2 (en) | 2007-11-27 |
| DE69838789D1 (de) | 2008-01-10 |
| CA2323889A1 (en) | 1998-09-17 |
| EP1006794B1 (en) | 2007-11-28 |
| US20050043242A1 (en) | 2005-02-24 |
| US20090280192A1 (en) | 2009-11-12 |
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