|
CA2259437C
(en)
*
|
1996-07-03 |
2006-12-05 |
Altea Technologies, Inc. |
Multiple mechanical microporation of skin or mucosa
|
|
US6797276B1
(en)
|
1996-11-14 |
2004-09-28 |
The United States Of America As Represented By The Secretary Of The Army |
Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
|
|
US20060002949A1
(en)
|
1996-11-14 |
2006-01-05 |
Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. |
Transcutaneous immunization without heterologous adjuvant
|
|
US5980898A
(en)
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
|
US6517532B1
(en)
|
1997-05-15 |
2003-02-11 |
Palomar Medical Technologies, Inc. |
Light energy delivery head
|
|
US6527716B1
(en)
|
1997-12-30 |
2003-03-04 |
Altea Technologies, Inc. |
Microporation of tissue for delivery of bioactive agents
|
|
US6173202B1
(en)
|
1998-03-06 |
2001-01-09 |
Spectrx, Inc. |
Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
|
|
US20020102729A1
(en)
*
|
1998-06-08 |
2002-08-01 |
Maclaughlin Fiona |
Formulations for electroporation
|
|
EP1124607B1
(en)
|
1998-07-14 |
2008-11-12 |
Altea Therapeutics Corporation |
Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport
|
|
CA2358584A1
(en)
*
|
1999-01-22 |
2000-07-27 |
Powderject Research Limited |
Method of enhancing needleless transdermal powdered drug delivery
|
|
ATE324922T1
(de)
|
1999-06-08 |
2006-06-15 |
Altea Therapeutics Corp |
Vorrichtung zur mikroporation eines biologischen gewebes mittels einer filmgewebe schnittstellenvorrichtung und verfahren
|
|
AU6076200A
(en)
|
1999-07-08 |
2001-01-30 |
Johnson & Johnson Consumer Companies, Inc. |
Exothermic bandage
|
|
US6890553B1
(en)
|
1999-07-08 |
2005-05-10 |
Johnson & Johnson Consumer Companies, Inc. |
Exothermic topical delivery device
|
|
US20030078499A1
(en)
|
1999-08-12 |
2003-04-24 |
Eppstein Jonathan A. |
Microporation of tissue for delivery of bioactive agents
|
|
US7113821B1
(en)
|
1999-08-25 |
2006-09-26 |
Johnson & Johnson Consumer Companies, Inc. |
Tissue electroperforation for enhanced drug delivery
|
|
US7133717B2
(en)
|
1999-08-25 |
2006-11-07 |
Johnson & Johnson Consumer Companies, Inc. |
Tissue electroperforation for enhanced drug delivery and diagnostic sampling
|
|
US7089053B1
(en)
*
|
1999-10-14 |
2006-08-08 |
Pola Chemical Industries Inc |
Compositions for drug administration by electroporation
|
|
WO2001076553A2
(en)
*
|
2000-04-06 |
2001-10-18 |
Sontra Medical, Inc. |
Method and device for enhanced transdermal drug delivery
|
|
US7404815B2
(en)
|
2000-05-01 |
2008-07-29 |
Lifescan, Inc. |
Tissue ablation by shear force for sampling biological fluids and delivering active agents
|
|
IL137689A0
(en)
*
|
2000-08-03 |
2001-10-31 |
L R Res & Dev Ltd |
System for enhanced chemical debridement
|
|
CN100421653C
(zh)
*
|
2000-09-08 |
2008-10-01 |
阿尔扎公司 |
通过抑制通道关闭来抑制药物透皮通量减少的方法
|
|
US7632522B2
(en)
|
2000-09-28 |
2009-12-15 |
Nanocyte Inc. |
Use of stinging cells/capsules for the delivery of active agents to keratinous substances
|
|
AU2001295850A1
(en)
|
2000-09-28 |
2002-04-08 |
Nanocyte Inc. |
Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
|
|
US6882884B1
(en)
|
2000-10-13 |
2005-04-19 |
Soundskin, L.L.C. |
Process for the stimulation of production of extracellular dermal proteins in human tissue
|
|
US6794376B2
(en)
*
|
2000-12-06 |
2004-09-21 |
William Beaumont Hospital |
Methods and compositions for enhancing diffusion of therapeutic agents through tissue
|
|
ES2310201T3
(es)
|
2001-02-13 |
2009-01-01 |
Government Of The United States Of America, As Represented By The Secretary Of The Army |
Vacuna para inmunizacion transcutanea contra la diarrea de los viajeros.
|
|
JP2004529906A
(ja)
|
2001-03-19 |
2004-09-30 |
イオマイ コーポレイシヨン |
経皮的免疫賦活
|
|
CA2476452A1
(en)
*
|
2002-02-15 |
2003-08-28 |
Zycos Inc. |
Electroporation methods for introducing bioactive agents into cells
|
|
CA2478822C
(en)
|
2002-03-11 |
2016-07-12 |
Passport Technologies, Inc. |
Transdermal drug delivery patch system, method of making same and method of using same
|
|
US9918665B2
(en)
|
2002-03-11 |
2018-03-20 |
Nitto Denko Corporation |
Transdermal porator and patch system and method for using same
|
|
ATE394125T1
(de)
|
2002-03-26 |
2008-05-15 |
Nanocyte Inc |
Nesselzellen mit expression eines exogenen polynucleotids, das ein therapeutisches, diagnostisches oder kosmetisches mittel kodiert, und diese nesselzellen verwendende verfahren, zusammensetzungen und vorrichtungen oder daraus gewonnene kapseln zur abgabe des therapeutischen, diagnostischen oder kosmetischen mittels in ein gewebe
|
|
WO2003089043A2
(en)
|
2002-04-19 |
2003-10-30 |
Transpharma Medical Ltd. |
Handheld transdermal drug delivery and analyte extraction
|
|
CA2489506A1
(en)
|
2002-06-19 |
2003-12-31 |
Palomar Medical Technologies, Inc. |
Method and apparatus for treatment of cutaneous and subcutaneous conditions
|
|
WO2006111201A1
(en)
|
2005-04-18 |
2006-10-26 |
Pantec Biosolutions Ag |
Laser microporator
|
|
US8834862B2
(en)
|
2005-04-19 |
2014-09-16 |
Nanocyte Inc. |
Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
|
|
US7856985B2
(en)
|
2005-04-22 |
2010-12-28 |
Cynosure, Inc. |
Method of treatment body tissue using a non-uniform laser beam
|
|
CA2620943A1
(en)
|
2005-09-02 |
2007-03-08 |
Iomai Corporation |
Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
|
|
US8346347B2
(en)
|
2005-09-15 |
2013-01-01 |
Palomar Medical Technologies, Inc. |
Skin optical characterization device
|
|
JP4921795B2
(ja)
|
2006-01-06 |
2012-04-25 |
株式会社東芝 |
超音波薬剤導入装置及び医用画像診断装置
|
|
JP4703724B2
(ja)
|
2006-04-28 |
2011-06-15 |
ゼルティック エステティックス インコーポレイテッド |
皮下の脂質リッチ細胞の冷却が改善された治療装置に使用する凍結防止剤
|
|
US7586957B2
(en)
|
2006-08-02 |
2009-09-08 |
Cynosure, Inc |
Picosecond laser apparatus and methods for its operation and use
|
|
US9132031B2
(en)
|
2006-09-26 |
2015-09-15 |
Zeltiq Aesthetics, Inc. |
Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
|
|
US8192474B2
(en)
|
2006-09-26 |
2012-06-05 |
Zeltiq Aesthetics, Inc. |
Tissue treatment methods
|
|
US20080077201A1
(en)
|
2006-09-26 |
2008-03-27 |
Juniper Medical, Inc. |
Cooling devices with flexible sensors
|
|
US20100004582A1
(en)
|
2006-10-25 |
2010-01-07 |
Pantec Biosolutions Ag |
Wide-Area Parasystemic Treatment of Skin Related Conditions
|
|
WO2008091878A1
(en)
|
2007-01-22 |
2008-07-31 |
Altea Therapeutics Corporation |
Transdermal porator and patch system and method for using same
|
|
US20080287839A1
(en)
|
2007-05-18 |
2008-11-20 |
Juniper Medical, Inc. |
Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
|
|
US8523927B2
(en)
|
2007-07-13 |
2013-09-03 |
Zeltiq Aesthetics, Inc. |
System for treating lipid-rich regions
|
|
EP3488833B1
(en)
|
2007-08-21 |
2025-10-22 |
Zeltiq Aesthetics, Inc. |
Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
|
|
CA2704740C
(en)
|
2007-10-09 |
2016-05-17 |
Transpharma Ltd. |
Magnetic patch coupling
|
|
CA2696227A1
(en)
|
2007-10-17 |
2009-04-23 |
Transpharma Medical Ltd. |
Dissolution rate verification
|
|
JP2011505899A
(ja)
|
2007-12-05 |
2011-03-03 |
シネロン メディカル リミテッド |
使い捨て可能な電磁気エネルギーアプリケータ及びそれを使用する方法
|
|
US8603073B2
(en)
|
2008-12-17 |
2013-12-10 |
Zeltiq Aesthetics, Inc. |
Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
|
|
US8606366B2
(en)
|
2009-02-18 |
2013-12-10 |
Syneron Medical Ltd. |
Skin treatment apparatus for personal use and method for using same
|
|
CA2760610C
(en)
|
2009-04-30 |
2017-09-19 |
Zeltiq Aesthetics, Inc. |
Device, system and method of removing heat from subcutaneous lipid-rich cells
|
|
US9919168B2
(en)
|
2009-07-23 |
2018-03-20 |
Palomar Medical Technologies, Inc. |
Method for improvement of cellulite appearance
|
|
KR101358374B1
(ko)
|
2009-07-30 |
2014-02-05 |
알마 레이저 엘티디. |
초음파발생봉
|
|
US9014799B2
(en)
*
|
2009-10-08 |
2015-04-21 |
Palo Alto Research Center Incorporated |
Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
|
|
US8834423B2
(en)
|
2009-10-23 |
2014-09-16 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Dissolvable microneedle arrays for transdermal delivery to human skin
|
|
JP2013517897A
(ja)
|
2010-01-25 |
2013-05-20 |
ゼルティック エステティックス インコーポレイテッド |
熱を皮下多脂質細胞から相変化冷却剤を介して非侵襲的に除去するための家庭用アプリケータ及びそれと関連した装置、システム及び方法
|
|
JP2013535998A
(ja)
*
|
2010-07-13 |
2013-09-19 |
スコット マクナルティ |
バイオメトリック情報をセンシングするためのシステム、方法、及び装置
|
|
US8676338B2
(en)
|
2010-07-20 |
2014-03-18 |
Zeltiq Aesthetics, Inc. |
Combined modality treatment systems, methods and apparatus for body contouring applications
|
|
SMT201700124T1
(it)
|
2010-09-03 |
2017-05-08 |
Valneva Austria Gmbh |
Polipeptide isolato delle proteine di tossina a e tossina b di c. difficile e relativi usi
|
|
US10722395B2
(en)
|
2011-01-25 |
2020-07-28 |
Zeltiq Aesthetics, Inc. |
Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
|
|
KR102136901B1
(ko)
|
2012-04-18 |
2020-07-22 |
싸이노슈어, 엘엘씨 |
피코초 레이저 장치 및 그를 사용한 표적 조직의 치료 방법
|
|
EP4112112A1
(en)
*
|
2012-05-01 |
2023-01-04 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
Tip-loaded microneedle arrays for transdermal insertion
|
|
US9545523B2
(en)
|
2013-03-14 |
2017-01-17 |
Zeltiq Aesthetics, Inc. |
Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
|
|
US9844460B2
(en)
|
2013-03-14 |
2017-12-19 |
Zeltiq Aesthetics, Inc. |
Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
|
|
EP2973894A2
(en)
|
2013-03-15 |
2016-01-20 |
Cynosure, Inc. |
Picosecond optical radiation systems and methods of use
|
|
US10517892B2
(en)
*
|
2013-10-22 |
2019-12-31 |
Medtronic Minimed, Inc. |
Methods and systems for inhibiting foreign-body responses in diabetic patients
|
|
WO2015117036A2
(en)
|
2014-01-30 |
2015-08-06 |
Zeltiq Aesthetics, Inc. |
Treatment systems, methods, and apparatuses for improving the appearance of skin and providing for other treatments
|
|
US10675176B1
(en)
|
2014-03-19 |
2020-06-09 |
Zeltiq Aesthetics, Inc. |
Treatment systems, devices, and methods for cooling targeted tissue
|
|
USD777338S1
(en)
|
2014-03-20 |
2017-01-24 |
Zeltiq Aesthetics, Inc. |
Cryotherapy applicator for cooling tissue
|
|
US11178823B2
(en)
|
2014-04-07 |
2021-11-23 |
Premier Citrus Apz, Llc |
Systems and methods for using light energy to facilitate penetration of substances in plants
|
|
US10278334B2
(en)
|
2014-04-07 |
2019-05-07 |
Premier Citrus Apz, Llc |
Systems and methods for delivering nucleic acids to a plant
|
|
US9265260B1
(en)
|
2014-04-07 |
2016-02-23 |
Gpd Technologies Llc |
Systems and methods for using light energy to facilitate penetration of substances in plants
|
|
US10952891B1
(en)
|
2014-05-13 |
2021-03-23 |
Zeltiq Aesthetics, Inc. |
Treatment systems with adjustable gap applicators and methods for cooling tissue
|
|
US10568759B2
(en)
|
2014-08-19 |
2020-02-25 |
Zeltiq Aesthetics, Inc. |
Treatment systems, small volume applicators, and methods for treating submental tissue
|
|
US10935174B2
(en)
|
2014-08-19 |
2021-03-02 |
Zeltiq Aesthetics, Inc. |
Stress relief couplings for cryotherapy apparatuses
|
|
WO2016054079A1
(en)
|
2014-09-29 |
2016-04-07 |
Zyomed Corp. |
Systems and methods for blood glucose and other analyte detection and measurement using collision computing
|
|
WO2016149673A1
(en)
|
2015-03-18 |
2016-09-22 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Bioactive components conjugated to substrates of microneedle arrays
|
|
WO2017066768A1
(en)
|
2015-10-16 |
2017-04-20 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
|
|
WO2017070112A1
(en)
|
2015-10-19 |
2017-04-27 |
Zeltiq Aesthetics, Inc. |
Vascular treatment systems, cooling devices, and methods for cooling vascular structures
|
|
ES2828686T3
(es)
*
|
2015-12-10 |
2021-05-27 |
Premier Citrus Apz Llc |
Método para usar la energía luminosa para facilitar la penetración de sustancias en plantas
|
|
US11744889B2
(en)
|
2016-01-05 |
2023-09-05 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Skin microenvironment targeted delivery for promoting immune and other responses
|
|
CA3009414A1
(en)
|
2016-01-07 |
2017-07-13 |
Zeltiq Aesthetics, Inc. |
Temperature-dependent adhesion between applicator and skin during cooling of tissue
|
|
US10765552B2
(en)
|
2016-02-18 |
2020-09-08 |
Zeltiq Aesthetics, Inc. |
Cooling cup applicators with contoured heads and liner assemblies
|
|
US11191278B2
(en)
|
2016-03-25 |
2021-12-07 |
Premier Citrus Apz, Llc |
Systems and methods for delivering nucleic acids to a plant
|
|
US9554738B1
(en)
|
2016-03-30 |
2017-01-31 |
Zyomed Corp. |
Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
|
|
US10555831B2
(en)
|
2016-05-10 |
2020-02-11 |
Zeltiq Aesthetics, Inc. |
Hydrogel substances and methods of cryotherapy
|
|
US10682297B2
(en)
|
2016-05-10 |
2020-06-16 |
Zeltiq Aesthetics, Inc. |
Liposomes, emulsions, and methods for cryotherapy
|
|
US11382790B2
(en)
|
2016-05-10 |
2022-07-12 |
Zeltiq Aesthetics, Inc. |
Skin freezing systems for treating acne and skin conditions
|
|
KR101929761B1
(ko)
*
|
2017-01-03 |
2018-12-17 |
(주)엠큐어 |
약물주입홀이 형성된 니들모듈
|
|
KR101938187B1
(ko)
*
|
2017-01-03 |
2019-01-14 |
(주)엠큐어 |
약물주입홀의 개폐가 가능한 니들모듈
|
|
CN110582245B
(zh)
|
2017-03-27 |
2022-09-16 |
诺服塞尔有限公司 |
用于皮内溶液递送的系统、设备和方法
|
|
US11076879B2
(en)
|
2017-04-26 |
2021-08-03 |
Zeltiq Aesthetics, Inc. |
Shallow surface cryotherapy applicators and related technology
|
|
WO2019165426A1
(en)
|
2018-02-26 |
2019-08-29 |
Cynosure, Inc. |
Q-switched cavity dumped sub-nanosecond laser
|
|
CN110604867B
(zh)
*
|
2018-06-15 |
2024-08-02 |
海创医疗科技(深圳)有限公司 |
一种超声中频导药仪
|
|
CA3107932A1
(en)
|
2018-07-31 |
2020-02-06 |
Zeltiq Aesthetics, Inc. |
Methods, devices, and systems for improving skin characteristics
|
|
US11622943B2
(en)
*
|
2019-05-10 |
2023-04-11 |
Chamkurkishtiah Panduranga Rao |
System and method for allergen-specific epicutaneous immunotherapy
|
|
US12588862B2
(en)
*
|
2019-05-10 |
2026-03-31 |
Tepit, Llc |
System and method for allergen-specific epicutaneous immunotherapy
|
|
CN113874065A
(zh)
|
2019-05-16 |
2021-12-31 |
联邦高等教育系统匹兹堡大学 |
用于皮肤和非皮肤药物递送的具有底切特征的微针阵列
|
|
CN112490602B
(zh)
*
|
2020-10-19 |
2021-09-24 |
电子科技大学 |
一种基于多层结构的THz导波调控装置
|
|
EP4482415A1
(en)
*
|
2022-02-24 |
2025-01-01 |
Teoresi S.p.A. |
Device for inducing cell permeability in a portion of tissue by opto-poration
|
|
KR102892381B1
(ko)
*
|
2024-08-20 |
2025-12-02 |
엘지전자 주식회사 |
미용장치
|