JP2001512034A5 - - Google Patents

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Publication number
JP2001512034A5
JP2001512034A5 JP2000505334A JP2000505334A JP2001512034A5 JP 2001512034 A5 JP2001512034 A5 JP 2001512034A5 JP 2000505334 A JP2000505334 A JP 2000505334A JP 2000505334 A JP2000505334 A JP 2000505334A JP 2001512034 A5 JP2001512034 A5 JP 2001512034A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000505334A
Other languages
Japanese (ja)
Other versions
JP4221145B2 (ja
JP2001512034A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/015764 external-priority patent/WO1999006595A1/en
Publication of JP2001512034A publication Critical patent/JP2001512034A/ja
Publication of JP2001512034A5 publication Critical patent/JP2001512034A5/ja
Application granted granted Critical
Publication of JP4221145B2 publication Critical patent/JP4221145B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2000505334A 1997-07-29 1998-07-29 最大の自己アセンブリを行う樹枝状核酸 Expired - Lifetime JP4221145B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5402097P 1997-07-29 1997-07-29
US60/054,020 1997-07-29
PCT/US1998/015764 WO1999006595A1 (en) 1997-07-29 1998-07-29 Dendritic nucleic acids exhibiting maximal self-assembly

Publications (3)

Publication Number Publication Date
JP2001512034A JP2001512034A (ja) 2001-08-21
JP2001512034A5 true JP2001512034A5 (enExample) 2005-12-22
JP4221145B2 JP4221145B2 (ja) 2009-02-12

Family

ID=21988251

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000505334A Expired - Lifetime JP4221145B2 (ja) 1997-07-29 1998-07-29 最大の自己アセンブリを行う樹枝状核酸

Country Status (8)

Country Link
US (1) US6274723B1 (enExample)
EP (1) EP1005573B1 (enExample)
JP (1) JP4221145B2 (enExample)
AT (1) ATE327344T1 (enExample)
AU (1) AU8601898A (enExample)
DE (1) DE69834645T2 (enExample)
ES (1) ES2270527T3 (enExample)
WO (1) WO1999006595A1 (enExample)

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US20040266706A1 (en) * 2002-11-05 2004-12-30 Muthiah Manoharan Cross-linked oligomeric compounds and their use in gene modulation
US9096636B2 (en) * 1996-06-06 2015-08-04 Isis Pharmaceuticals, Inc. Chimeric oligomeric compounds and their use in gene modulation
US7812149B2 (en) 1996-06-06 2010-10-12 Isis Pharmaceuticals, Inc. 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
US5898031A (en) * 1996-06-06 1999-04-27 Isis Pharmaceuticals, Inc. Oligoribonucleotides for cleaving RNA
GB9811403D0 (en) * 1998-05-27 1998-07-22 Isis Innovation Polynucleotide multimers and their use in hybridisation assays
WO2001066555A1 (en) * 2000-03-08 2001-09-13 Datascope Investment Corp. Methods for assay and detection on a microarray
CA2387755C (en) * 2000-03-31 2007-07-03 Sanko Junyaku Co., Ltd. Probe for constructing probe polymer, method of constructing probe polymer and utilization thereof
AU2001282920A1 (en) * 2000-07-19 2002-01-30 Genisphere Inc Methods for detecting and assaying nucleic acid sequences
US7011943B2 (en) * 2000-09-06 2006-03-14 Transnetyx, Inc. Method for detecting a designated genetic sequence in murine genomic DNA
ES2273892T3 (es) 2000-10-11 2007-05-16 Sanko Junyaku Co., Ltd. Procedimiento de construccion de sondas de autoensamblaje y procedimiento de deteccion de las mismas.
WO2003040411A1 (en) * 2001-11-05 2003-05-15 Transgenomic, Inc. Methods, systems, and kits for analysis of polynucleotides
US20040009495A1 (en) * 2001-12-07 2004-01-15 Whitehead Institute For Biomedical Research Methods and products related to drug screening using gene expression patterns
US20040023248A1 (en) * 2001-12-07 2004-02-05 Whitehead Institiute For Biomedical Research Methods and reagents for improving nucleic acid detection
US20030175709A1 (en) * 2001-12-20 2003-09-18 Murphy George L. Method and system for depleting rRNA populations
EP2957568B1 (en) 2002-11-05 2016-12-21 Ionis Pharmaceuticals, Inc. Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
US8569474B2 (en) 2004-03-09 2013-10-29 Isis Pharmaceuticals, Inc. Double stranded constructs comprising one or more short strands hybridized to a longer strand
ATE541054T1 (de) 2004-05-12 2012-01-15 Nanosphere Inc Bio-barcode erkennung für zielmoleküle
US8394947B2 (en) 2004-06-03 2013-03-12 Isis Pharmaceuticals, Inc. Positionally modified siRNA constructs
US7884086B2 (en) 2004-09-08 2011-02-08 Isis Pharmaceuticals, Inc. Conjugates for use in hepatocyte free uptake assays
US20090137415A1 (en) * 2005-08-05 2009-05-28 Euclid Diagnostics Llc SUBTRACTIVE SEPARATION AND AMPLIFICATION OF NON-RIBOSOMAL TRANSCRIBED RNA (nrRNA)
AU2007208310B2 (en) * 2006-01-23 2012-05-31 Drexel University Self-exciting, self-sensing piezoelectric cantilever sensor
US8286486B2 (en) * 2006-05-10 2012-10-16 Drexel University Molecular control of surface coverage
US20070275388A1 (en) * 2006-05-25 2007-11-29 Daniel Ryan Dendrimers that possess a single target annealing site and uses thereof
US8512947B2 (en) * 2007-02-16 2013-08-20 Drexel University Detection of nucleic acids using a cantilever sensor
US7892759B2 (en) 2007-02-16 2011-02-22 Drexel University Enhanced sensitivity of a cantilever sensor via specific bindings
US9707299B2 (en) * 2007-05-23 2017-07-18 The Trustees Of The University Of Pennsylvania Targeted carriers for intracellular drug delivery
WO2009035732A2 (en) * 2007-05-30 2009-03-19 Drexel University Detection and quantification of biomarkers via a piezoelectric cantilever sensor
US8236508B2 (en) * 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
EP2320953B1 (en) 2008-08-08 2015-07-15 Genisphere, LLC Long-acting dna dendrimers and methods thereof
US20110206611A1 (en) 2010-02-24 2011-08-25 Genisphere, Llc DNA Dendrimers as Thermal Ablation Devices
US20130035259A1 (en) 2010-11-22 2013-02-07 The University Of Chicago Methods and/or Systems Producing and Providing Sets of Oligonucleotide Conjugates for Assays and Detections
WO2013177046A1 (en) 2012-05-21 2013-11-28 Solulink, Inc. Methods and/or use of oligonucleotide conjugates for suppressing background due to cross-hybridization
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
CN105188764B (zh) 2013-03-21 2020-03-20 詹尼斯费尔公司 Dna嵌入剂的细胞递送
WO2017143171A1 (en) * 2016-02-19 2017-08-24 Genisphere Llc Nucleic acid carriers and therapeutic methods of use
AU2017220012B2 (en) 2016-02-19 2024-05-02 Code Biotherapeutics, Inc. Nucleic acid carriers and therapeutic methods of use
WO2022059462A1 (ja) * 2020-09-17 2022-03-24 横河電機株式会社 核酸配列計測方法、および核酸配列計測用キット

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
US5288609A (en) * 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US5175270A (en) 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
US5561043A (en) * 1994-01-31 1996-10-01 Trustees Of Boston University Self-assembling multimeric nucleic acid constructs

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