ATE327344T1 - Dendritische nukleinsäuren mit maximaler selbstzusammenlagerung - Google Patents
Dendritische nukleinsäuren mit maximaler selbstzusammenlagerungInfo
- Publication number
- ATE327344T1 ATE327344T1 AT98937269T AT98937269T ATE327344T1 AT E327344 T1 ATE327344 T1 AT E327344T1 AT 98937269 T AT98937269 T AT 98937269T AT 98937269 T AT98937269 T AT 98937269T AT E327344 T1 ATE327344 T1 AT E327344T1
- Authority
- AT
- Austria
- Prior art keywords
- monomers
- nucleic acids
- collective storage
- maximum self
- dendrimeric
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 239000000178 monomer Substances 0.000 abstract 4
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000001338 self-assembly Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5402097P | 1997-07-29 | 1997-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE327344T1 true ATE327344T1 (de) | 2006-06-15 |
Family
ID=21988251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98937269T ATE327344T1 (de) | 1997-07-29 | 1998-07-29 | Dendritische nukleinsäuren mit maximaler selbstzusammenlagerung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6274723B1 (enExample) |
| EP (1) | EP1005573B1 (enExample) |
| JP (1) | JP4221145B2 (enExample) |
| AT (1) | ATE327344T1 (enExample) |
| AU (1) | AU8601898A (enExample) |
| DE (1) | DE69834645T2 (enExample) |
| ES (1) | ES2270527T3 (enExample) |
| WO (1) | WO1999006595A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040266706A1 (en) * | 2002-11-05 | 2004-12-30 | Muthiah Manoharan | Cross-linked oligomeric compounds and their use in gene modulation |
| US5898031A (en) * | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| US7812149B2 (en) | 1996-06-06 | 2010-10-12 | Isis Pharmaceuticals, Inc. | 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations |
| US9096636B2 (en) * | 1996-06-06 | 2015-08-04 | Isis Pharmaceuticals, Inc. | Chimeric oligomeric compounds and their use in gene modulation |
| GB9811403D0 (en) * | 1998-05-27 | 1998-07-22 | Isis Innovation | Polynucleotide multimers and their use in hybridisation assays |
| AU2001247328C1 (en) * | 2000-03-08 | 2006-10-26 | Datascope Investment Corp. | Methods for assay and detection on a microarray |
| DK1188841T3 (da) * | 2000-03-31 | 2009-04-20 | Sanko Junyaku Kk | Probe til fremstilling af en polymerprobe, fremgangsmåde til fremstilling af en polymerprobe samt anvendelse af polymerproben |
| WO2002006511A2 (en) * | 2000-07-19 | 2002-01-24 | Genisphere Inc | Methods for detecting and assaying nucleic acid sequences |
| US7011943B2 (en) * | 2000-09-06 | 2006-03-14 | Transnetyx, Inc. | Method for detecting a designated genetic sequence in murine genomic DNA |
| ES2273892T3 (es) | 2000-10-11 | 2007-05-16 | Sanko Junyaku Co., Ltd. | Procedimiento de construccion de sondas de autoensamblaje y procedimiento de deteccion de las mismas. |
| EP1451350A4 (en) * | 2001-11-05 | 2006-05-10 | Transgenomic Inc | PROCESSES, SYSTEMS AND KITS FOR THE ANALYSIS OF POLYNUCLEOTIDES |
| US20040009495A1 (en) * | 2001-12-07 | 2004-01-15 | Whitehead Institute For Biomedical Research | Methods and products related to drug screening using gene expression patterns |
| US20040023248A1 (en) * | 2001-12-07 | 2004-02-05 | Whitehead Institiute For Biomedical Research | Methods and reagents for improving nucleic acid detection |
| US20030175709A1 (en) * | 2001-12-20 | 2003-09-18 | Murphy George L. | Method and system for depleting rRNA populations |
| WO2004044136A2 (en) | 2002-11-05 | 2004-05-27 | Isis Pharmaceuticals, Inc. | Compositions comprising alternating 2’-modified nucleosides for use in gene modulation |
| US8569474B2 (en) | 2004-03-09 | 2013-10-29 | Isis Pharmaceuticals, Inc. | Double stranded constructs comprising one or more short strands hybridized to a longer strand |
| JP2007537450A (ja) | 2004-05-12 | 2007-12-20 | ナノスフェアー インコーポレイテッド | バイオバーコードに基づく標的検体の検出 |
| US8394947B2 (en) | 2004-06-03 | 2013-03-12 | Isis Pharmaceuticals, Inc. | Positionally modified siRNA constructs |
| US7884086B2 (en) | 2004-09-08 | 2011-02-08 | Isis Pharmaceuticals, Inc. | Conjugates for use in hepatocyte free uptake assays |
| WO2007019444A2 (en) * | 2005-08-05 | 2007-02-15 | Euclid Diagnostics Llc | Subtractive separation and amplification of non-ribosomal transcribed rna (nrrna) |
| US7942056B2 (en) * | 2006-01-23 | 2011-05-17 | Drexel University | Self-exciting, self-sensing piezoelectric cantilever sensor |
| WO2007133619A1 (en) * | 2006-05-10 | 2007-11-22 | Drexel University | Molecular control of surface coverage |
| US20070275388A1 (en) * | 2006-05-25 | 2007-11-29 | Daniel Ryan | Dendrimers that possess a single target annealing site and uses thereof |
| US7892759B2 (en) | 2007-02-16 | 2011-02-22 | Drexel University | Enhanced sensitivity of a cantilever sensor via specific bindings |
| US8512947B2 (en) * | 2007-02-16 | 2013-08-20 | Drexel University | Detection of nucleic acids using a cantilever sensor |
| WO2008147526A1 (en) | 2007-05-23 | 2008-12-04 | The Trustees Of The University Of Pennsylvania | Targeted carriers for intracellular drug delivery |
| US7993854B2 (en) * | 2007-05-30 | 2011-08-09 | Drexel University | Detection and quantification of biomarkers via a piezoelectric cantilever sensor |
| US8236508B2 (en) * | 2008-01-29 | 2012-08-07 | Drexel University | Detecting and measuring live pathogens utilizing a mass detection device |
| WO2010017544A2 (en) | 2008-08-08 | 2010-02-11 | Genisphere, Inc. | Long-acting dna dendrimers and methods thereof |
| US20110206611A1 (en) | 2010-02-24 | 2011-08-25 | Genisphere, Llc | DNA Dendrimers as Thermal Ablation Devices |
| US20130035259A1 (en) | 2010-11-22 | 2013-02-07 | The University Of Chicago | Methods and/or Systems Producing and Providing Sets of Oligonucleotide Conjugates for Assays and Detections |
| WO2013177046A1 (en) | 2012-05-21 | 2013-11-28 | Solulink, Inc. | Methods and/or use of oligonucleotide conjugates for suppressing background due to cross-hybridization |
| US9651549B2 (en) | 2012-07-13 | 2017-05-16 | Genisphere, Llc | Lateral flow assays using DNA dendrimers |
| WO2014153394A1 (en) | 2013-03-21 | 2014-09-25 | Genisphere, Llc | Cellular delivery of dna intercalating agents |
| JP7366541B2 (ja) | 2016-02-19 | 2023-10-23 | コード バイオセラピューティクス インコーポレイテッド | 核酸キャリア及び治療上の使用方法 |
| WO2017143171A1 (en) * | 2016-02-19 | 2017-08-24 | Genisphere Llc | Nucleic acid carriers and therapeutic methods of use |
| EP4215620A4 (en) * | 2020-09-17 | 2024-10-23 | Yokogawa Electric Corporation | NUCLEIC ACID SEQUENCE MEASURING METHOD AND NUCLEIC ACID SEQUENCE MEASURING KIT |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5288609A (en) * | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
| US5175270A (en) * | 1986-09-10 | 1992-12-29 | Polyprobe, Inc. | Reagents for detecting and assaying nucleic acid sequences |
| CA2039517C (en) * | 1990-04-03 | 2006-11-07 | David Segev | Dna probe signal amplification |
| US5561043A (en) * | 1994-01-31 | 1996-10-01 | Trustees Of Boston University | Self-assembling multimeric nucleic acid constructs |
-
1998
- 1998-07-29 DE DE69834645T patent/DE69834645T2/de not_active Expired - Lifetime
- 1998-07-29 EP EP98937269A patent/EP1005573B1/en not_active Expired - Lifetime
- 1998-07-29 AU AU86018/98A patent/AU8601898A/en not_active Abandoned
- 1998-07-29 WO PCT/US1998/015764 patent/WO1999006595A1/en not_active Ceased
- 1998-07-29 JP JP2000505334A patent/JP4221145B2/ja not_active Expired - Lifetime
- 1998-07-29 AT AT98937269T patent/ATE327344T1/de not_active IP Right Cessation
- 1998-07-29 ES ES98937269T patent/ES2270527T3/es not_active Expired - Lifetime
-
2000
- 2000-01-27 US US09/492,471 patent/US6274723B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1005573B1 (en) | 2006-05-24 |
| AU8601898A (en) | 1999-02-22 |
| DE69834645D1 (de) | 2006-06-29 |
| JP4221145B2 (ja) | 2009-02-12 |
| US6274723B1 (en) | 2001-08-14 |
| JP2001512034A (ja) | 2001-08-21 |
| EP1005573A1 (en) | 2000-06-07 |
| DE69834645T2 (de) | 2007-05-03 |
| EP1005573A4 (en) | 2004-11-10 |
| ES2270527T3 (es) | 2007-04-01 |
| WO1999006595A1 (en) | 1999-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |