AU8601898A - Dendritic nucleic acids exhibiting maximal self-assembly - Google Patents

Dendritic nucleic acids exhibiting maximal self-assembly

Info

Publication number
AU8601898A
AU8601898A AU86018/98A AU8601898A AU8601898A AU 8601898 A AU8601898 A AU 8601898A AU 86018/98 A AU86018/98 A AU 86018/98A AU 8601898 A AU8601898 A AU 8601898A AU 8601898 A AU8601898 A AU 8601898A
Authority
AU
Australia
Prior art keywords
assembly
monomers
nucleic acids
dendrimeric
subsequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU86018/98A
Other languages
English (en)
Inventor
Thor W. Nilsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Polyprobe Inc
Original Assignee
Polyprobe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyprobe Inc filed Critical Polyprobe Inc
Publication of AU8601898A publication Critical patent/AU8601898A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU86018/98A 1997-07-29 1998-07-29 Dendritic nucleic acids exhibiting maximal self-assembly Abandoned AU8601898A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5402097P 1997-07-29 1997-07-29
US60054020 1997-07-29
PCT/US1998/015764 WO1999006595A1 (en) 1997-07-29 1998-07-29 Dendritic nucleic acids exhibiting maximal self-assembly

Publications (1)

Publication Number Publication Date
AU8601898A true AU8601898A (en) 1999-02-22

Family

ID=21988251

Family Applications (1)

Application Number Title Priority Date Filing Date
AU86018/98A Abandoned AU8601898A (en) 1997-07-29 1998-07-29 Dendritic nucleic acids exhibiting maximal self-assembly

Country Status (8)

Country Link
US (1) US6274723B1 (enExample)
EP (1) EP1005573B1 (enExample)
JP (1) JP4221145B2 (enExample)
AT (1) ATE327344T1 (enExample)
AU (1) AU8601898A (enExample)
DE (1) DE69834645T2 (enExample)
ES (1) ES2270527T3 (enExample)
WO (1) WO1999006595A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040266706A1 (en) * 2002-11-05 2004-12-30 Muthiah Manoharan Cross-linked oligomeric compounds and their use in gene modulation
US5898031A (en) * 1996-06-06 1999-04-27 Isis Pharmaceuticals, Inc. Oligoribonucleotides for cleaving RNA
US7812149B2 (en) 1996-06-06 2010-10-12 Isis Pharmaceuticals, Inc. 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
US9096636B2 (en) * 1996-06-06 2015-08-04 Isis Pharmaceuticals, Inc. Chimeric oligomeric compounds and their use in gene modulation
GB9811403D0 (en) * 1998-05-27 1998-07-22 Isis Innovation Polynucleotide multimers and their use in hybridisation assays
AU2001247328C1 (en) * 2000-03-08 2006-10-26 Datascope Investment Corp. Methods for assay and detection on a microarray
DK1188841T3 (da) * 2000-03-31 2009-04-20 Sanko Junyaku Kk Probe til fremstilling af en polymerprobe, fremgangsmåde til fremstilling af en polymerprobe samt anvendelse af polymerproben
WO2002006511A2 (en) * 2000-07-19 2002-01-24 Genisphere Inc Methods for detecting and assaying nucleic acid sequences
US7011943B2 (en) * 2000-09-06 2006-03-14 Transnetyx, Inc. Method for detecting a designated genetic sequence in murine genomic DNA
ES2273892T3 (es) 2000-10-11 2007-05-16 Sanko Junyaku Co., Ltd. Procedimiento de construccion de sondas de autoensamblaje y procedimiento de deteccion de las mismas.
EP1451350A4 (en) * 2001-11-05 2006-05-10 Transgenomic Inc PROCESSES, SYSTEMS AND KITS FOR THE ANALYSIS OF POLYNUCLEOTIDES
US20040009495A1 (en) * 2001-12-07 2004-01-15 Whitehead Institute For Biomedical Research Methods and products related to drug screening using gene expression patterns
US20040023248A1 (en) * 2001-12-07 2004-02-05 Whitehead Institiute For Biomedical Research Methods and reagents for improving nucleic acid detection
US20030175709A1 (en) * 2001-12-20 2003-09-18 Murphy George L. Method and system for depleting rRNA populations
WO2004044136A2 (en) 2002-11-05 2004-05-27 Isis Pharmaceuticals, Inc. Compositions comprising alternating 2’-modified nucleosides for use in gene modulation
US8569474B2 (en) 2004-03-09 2013-10-29 Isis Pharmaceuticals, Inc. Double stranded constructs comprising one or more short strands hybridized to a longer strand
JP2007537450A (ja) 2004-05-12 2007-12-20 ナノスフェアー　インコーポレイテッド バイオバーコードに基づく標的検体の検出
US8394947B2 (en) 2004-06-03 2013-03-12 Isis Pharmaceuticals, Inc. Positionally modified siRNA constructs
US7884086B2 (en) 2004-09-08 2011-02-08 Isis Pharmaceuticals, Inc. Conjugates for use in hepatocyte free uptake assays
WO2007019444A2 (en) * 2005-08-05 2007-02-15 Euclid Diagnostics Llc Subtractive separation and amplification of non-ribosomal transcribed rna (nrrna)
US7942056B2 (en) * 2006-01-23 2011-05-17 Drexel University Self-exciting, self-sensing piezoelectric cantilever sensor
WO2007133619A1 (en) * 2006-05-10 2007-11-22 Drexel University Molecular control of surface coverage
US20070275388A1 (en) * 2006-05-25 2007-11-29 Daniel Ryan Dendrimers that possess a single target annealing site and uses thereof
US7892759B2 (en) 2007-02-16 2011-02-22 Drexel University Enhanced sensitivity of a cantilever sensor via specific bindings
US8512947B2 (en) * 2007-02-16 2013-08-20 Drexel University Detection of nucleic acids using a cantilever sensor
WO2008147526A1 (en) 2007-05-23 2008-12-04 The Trustees Of The University Of Pennsylvania Targeted carriers for intracellular drug delivery
US7993854B2 (en) * 2007-05-30 2011-08-09 Drexel University Detection and quantification of biomarkers via a piezoelectric cantilever sensor
US8236508B2 (en) * 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
WO2010017544A2 (en) 2008-08-08 2010-02-11 Genisphere, Inc. Long-acting dna dendrimers and methods thereof
US20110206611A1 (en) 2010-02-24 2011-08-25 Genisphere, Llc DNA Dendrimers as Thermal Ablation Devices
US20130035259A1 (en) 2010-11-22 2013-02-07 The University Of Chicago Methods and/or Systems Producing and Providing Sets of Oligonucleotide Conjugates for Assays and Detections
WO2013177046A1 (en) 2012-05-21 2013-11-28 Solulink, Inc. Methods and/or use of oligonucleotide conjugates for suppressing background due to cross-hybridization
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
WO2014153394A1 (en) 2013-03-21 2014-09-25 Genisphere, Llc Cellular delivery of dna intercalating agents
JP7366541B2 (ja) 2016-02-19 2023-10-23 コード バイオセラピューティクス インコーポレイテッド 核酸キャリア及び治療上の使用方法
WO2017143171A1 (en) * 2016-02-19 2017-08-24 Genisphere Llc Nucleic acid carriers and therapeutic methods of use
EP4215620A4 (en) * 2020-09-17 2024-10-23 Yokogawa Electric Corporation NUCLEIC ACID SEQUENCE MEASURING METHOD AND NUCLEIC ACID SEQUENCE MEASURING KIT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288609A (en) * 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
US5561043A (en) * 1994-01-31 1996-10-01 Trustees Of Boston University Self-assembling multimeric nucleic acid constructs

Also Published As

Publication number Publication date
EP1005573B1 (en) 2006-05-24
DE69834645D1 (de) 2006-06-29
JP4221145B2 (ja) 2009-02-12
US6274723B1 (en) 2001-08-14
JP2001512034A (ja) 2001-08-21
EP1005573A1 (en) 2000-06-07
DE69834645T2 (de) 2007-05-03
EP1005573A4 (en) 2004-11-10
ES2270527T3 (es) 2007-04-01
ATE327344T1 (de) 2006-06-15
WO1999006595A1 (en) 1999-02-11

Similar Documents

Publication Publication Date Title
AU8601898A (en) Dendritic nucleic acids exhibiting maximal self-assembly
Hudson Ferrocene polymers: current architectures, syntheses and utility
EP1700603A3 (en) Immunostimulatory nucleic acids
EP1310507A3 (en) Novel peptide nucleic acids
WO1998026093A3 (en) Fluorescent nucleotide analog hairpin formation for detection of nucleic acid hybridization
EP1857547A3 (en) Further novel forms of interfering RNA molecules
CA2382521A1 (en) Oligonucleotide n3'.fwdarw.p5' thiophosphoramidates: their synthesis and use
CA2283509A1 (en) Novel bicyclonucleoside and oligonucleotide analogue
ATE225369T1 (de) Doppelsträngige peptidenukleinsäuren
HUT66597A (en) Peptide nucleic acids
EP1700915A3 (en) Enzymatic DNA molecules
CA2223678A1 (en) Covalently linked oligonucleotide minor groove binder conjugates
WO1998002582A3 (en) Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m?
AU4966997A (en) Novel nucleotide analogues
CA2202280A1 (en) Sugar modified nucleosides and their use for synthesis of oligonucleotides
WO1999010358A3 (de) Verfahren zum herstellen von nukleinsäurepolymeren
CA2082842A1 (en) Nucleic acid target generation
EP2631293A3 (en) Human microRNAs and methods for inhibiting same
WO2001049687A3 (en) Cyclohexene nucleic acids
WO1999049082A3 (en) Modified nucleotides and methods useful for nucleic acid sequencing
DE69838950D1 (de) Multiplex strandverdrängungsamplifizierung
ATE174599T1 (de) Bindungskompetente oligomere, die 2',5'-bindungen enthalten
JP2001120012A5 (enExample)
Nielsen et al. Incorporation of (R)-and (S)-3′, 4′-seco-thymidine into oligodeoxynucleotides: hybridization properties and enzymatic stability
DE69833435D1 (de) Peptidnukleinsäure monomere und oligomere

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase