JP2001511644A - 核酸を精製するための方法および装置 - Google Patents
核酸を精製するための方法および装置Info
- Publication number
- JP2001511644A JP2001511644A JP53160798A JP53160798A JP2001511644A JP 2001511644 A JP2001511644 A JP 2001511644A JP 53160798 A JP53160798 A JP 53160798A JP 53160798 A JP53160798 A JP 53160798A JP 2001511644 A JP2001511644 A JP 2001511644A
- Authority
- JP
- Japan
- Prior art keywords
- container
- sample
- nucleic acid
- nucleic acids
- sealing member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 111
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- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
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- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 2
- 229910021536 Zeolite Inorganic materials 0.000 claims description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 229910044991 metal oxide Inorganic materials 0.000 claims description 2
- 150000004706 metal oxides Chemical class 0.000 claims description 2
- 229910003455 mixed metal oxide Inorganic materials 0.000 claims description 2
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 claims description 2
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 2
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims description 2
- 239000010457 zeolite Substances 0.000 claims description 2
- 229910001928 zirconium oxide Inorganic materials 0.000 claims description 2
- 238000002955 isolation Methods 0.000 abstract description 7
- 230000005012 migration Effects 0.000 abstract description 2
- 238000013508 migration Methods 0.000 abstract description 2
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- 108090000623 proteins and genes Proteins 0.000 description 9
- 102000004169 proteins and genes Human genes 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
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- 238000003752 polymerase chain reaction Methods 0.000 description 5
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- 150000003839 salts Chemical class 0.000 description 4
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- 230000003196 chaotropic effect Effects 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
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- 102000004190 Enzymes Human genes 0.000 description 2
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- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
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- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
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- 101000749837 Bos taurus Leukocyte cell-derived chemotaxin 1 Proteins 0.000 description 1
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 description 1
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- 108010067770 Endopeptidase K Proteins 0.000 description 1
- 101710181478 Envelope glycoprotein GP350 Proteins 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 101710163270 Nuclease Proteins 0.000 description 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 description 1
- 108091093037 Peptide nucleic acid Proteins 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920004890 Triton X-100 Polymers 0.000 description 1
- 239000013504 Triton X-100 Substances 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 241000726445 Viroids Species 0.000 description 1
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- ZRALSGWEFCBTJO-UHFFFAOYSA-O guanidinium Chemical compound NC(N)=[NH2+] ZRALSGWEFCBTJO-UHFFFAOYSA-O 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 239000012139 lysis buffer Substances 0.000 description 1
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- 238000010369 molecular cloning Methods 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
- B01L3/5635—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors connecting two containers face to face, e.g. comprising a filter
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702907.8 | 1997-01-28 | ||
| DE19702907A DE19702907A1 (de) | 1997-01-28 | 1997-01-28 | Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren |
| PCT/EP1998/000408 WO1998032877A1 (de) | 1997-01-28 | 1998-01-26 | Verfahren und vorrichtung zur reinigung von nukleinsäuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001511644A true JP2001511644A (ja) | 2001-08-14 |
| JP2001511644A5 JP2001511644A5 (enExample) | 2005-08-11 |
Family
ID=7818496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53160798A Withdrawn JP2001511644A (ja) | 1997-01-28 | 1998-01-26 | 核酸を精製するための方法および装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6720417B1 (enExample) |
| EP (1) | EP0964934A1 (enExample) |
| JP (1) | JP2001511644A (enExample) |
| AU (1) | AU6213298A (enExample) |
| DE (1) | DE19702907A1 (enExample) |
| WO (1) | WO1998032877A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004329213A (ja) * | 2003-05-01 | 2004-11-25 | Veridex Llc | 細胞および組織からのｒｎａ迅速抽出 |
| WO2008075501A1 (ja) | 2006-12-19 | 2008-06-26 | Konica Minolta Medical & Graphic, Inc. | 回転式抽出容器、それを用いた細胞種の同定方法、遺伝子検出方法、及び自動核酸抽出装置 |
| JP2016524706A (ja) * | 2013-05-24 | 2016-08-18 | オッカム バイオラブス，インコーポレイティド | 核酸サンプルを回収するためのシステム及び方法 |
| US10287570B2 (en) | 2014-11-21 | 2019-05-14 | Occam Biolabs, Inc. | System and method for collecting a sample of nucleic acid |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19702907A1 (de) * | 1997-01-28 | 1998-07-30 | Boehringer Mannheim Gmbh | Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren |
| DE19746874A1 (de) * | 1997-10-23 | 1999-04-29 | Qiagen Gmbh | Verfahren zur Isolierung und Reinigung von Nukleinsäuren an hydrophoben Oberflächen - insbesondere unter Verwendung hydrophober Membranen |
| DE19836559A1 (de) * | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| DE60010058T2 (de) * | 1999-02-26 | 2005-04-28 | Exact Sciences Corp., Marlborough | Biochemische reinigungsgeräte mit immobilisierten fangsonden und ihre anwendungen |
| SE9904539D0 (sv) * | 1999-12-10 | 1999-12-10 | Alphahelix Ab | Method and device for the handling of samples and reagents |
| DE10006662A1 (de) | 2000-02-15 | 2001-08-23 | Antigen Produktions Gmbh | Gefäß zur Nukleinsäureanalytik |
| AU2002325617A1 (en) * | 2001-08-29 | 2003-03-10 | Hexal Pharma Gmbh | Method and device for preparing a sample of biological origin in order to determine at least one constituent contained therein |
| WO2004080357A1 (es) | 2003-03-14 | 2004-09-23 | Ferreyro Irigoyen Roque Humber | Dispositivo hidraulico de inyección de cemento oseo en la vertebroplastiá percutánea |
| US8066713B2 (en) | 2003-03-31 | 2011-11-29 | Depuy Spine, Inc. | Remotely-activated vertebroplasty injection device |
| US8415407B2 (en) | 2004-03-21 | 2013-04-09 | Depuy Spine, Inc. | Methods, materials, and apparatus for treating bone and other tissue |
| WO2006011152A2 (en) | 2004-06-17 | 2006-02-02 | Disc-O-Tech Medical Technologies, Ltd. | Methods for treating bone and other tissue |
| WO2005030034A2 (en) | 2003-09-26 | 2005-04-07 | Depuy Spine, Inc. | Device for delivering viscous material |
| US7897378B2 (en) | 2004-03-18 | 2011-03-01 | Roche Molecular Systems, Inc. | Method and device for purifying nucleic acids |
| DE102004058828B4 (de) * | 2004-10-28 | 2010-08-19 | Progen Biotechnik Gmbh | Vorrichtung und Verfahren zur parallelen Aufbereitung von Biopolymeren |
| US20060166223A1 (en) * | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
| US9381024B2 (en) | 2005-07-31 | 2016-07-05 | DePuy Synthes Products, Inc. | Marked tools |
| US9918767B2 (en) | 2005-08-01 | 2018-03-20 | DePuy Synthes Products, Inc. | Temperature control system |
| US8360629B2 (en) | 2005-11-22 | 2013-01-29 | Depuy Spine, Inc. | Mixing apparatus having central and planetary mixing elements |
| US7608399B2 (en) * | 2006-06-26 | 2009-10-27 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
| US8163535B2 (en) * | 2006-06-26 | 2012-04-24 | Blood Cell Storage, Inc. | Devices and processes for nucleic acid extraction |
| KR100805449B1 (ko) | 2006-08-18 | 2008-02-20 | 배정훈 | 비석분말을 분자체로 이용하여 아가로스겔에서 dna를정제하는 방법 |
| AU2007297097A1 (en) | 2006-09-14 | 2008-03-20 | Depuy Spine, Inc. | Bone cement and methods of use thereof |
| CA2747850C (en) * | 2006-10-19 | 2013-05-14 | Depuy Spine, Inc. | Fluid delivery system |
| JP2010537797A (ja) * | 2007-05-23 | 2010-12-09 | ニプロ インク | 真空濾過システム中の泡の制御のための方法及び装置 |
| US8231012B2 (en) * | 2007-07-26 | 2012-07-31 | Roush Life Sciences, Llc | Filtrate storage system |
| EP2183040B1 (en) * | 2007-07-26 | 2012-03-07 | Roush Life Sciences, LLC | Methods and apparatus for supporting a vacuum filtration device |
| US20090048438A1 (en) * | 2007-08-13 | 2009-02-19 | Taigen Bioscience Corporation. | Method for washing a column and method for extracting membrane-bound target molecules |
| EP2055385B1 (en) | 2007-10-31 | 2010-05-26 | Roche Diagnostics GmbH | Method and device for purifying nucleic acids |
| KR20110101143A (ko) * | 2008-11-04 | 2011-09-15 | 블러드 셀 스토리지 인코퍼레이티드 | 굴곡 유리 표면 상에서의 핵산 추출 |
| WO2012159063A2 (en) | 2011-05-19 | 2012-11-22 | Blood Cell Strorage, Inc. | Gravity flow fluidic device for nucleic acid extraction |
| IL321539A (en) * | 2017-07-27 | 2025-08-01 | Bio Merieux Inc | Isolation tube |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991007648A1 (en) * | 1989-11-08 | 1991-05-30 | Fmc Corporation | Combined centrifuge tube and porous selection means for separation and recovery of biological materials |
| US5438128A (en) * | 1992-02-07 | 1995-08-01 | Millipore Corporation | Method for rapid purifiction of nucleic acids using layered ion-exchange membranes |
| CA2170604C (en) * | 1993-08-30 | 2007-03-13 | Vikas V. Padhye | Nucleic acid purification compositions and methods |
| DE19581626T1 (de) * | 1994-04-08 | 1997-04-24 | Amicon Inc | Verfahren und Vorrichtung zur Ioslierung und Reinigung von biologisch aktiven Komplexen |
| JPH10504834A (ja) * | 1994-08-29 | 1998-05-12 | アクゾ・ノベル・エヌ・ベー | 核酸などの生物材料の単離に使用する装置 |
| DE19512369A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | Vorrichtung zur Isolierung von Nukleinsäuren |
| ES2181819T3 (es) * | 1995-04-01 | 2003-03-01 | Roche Diagnostics Gmbh | Procedimiento para la fijacion de un material biologico. |
| US5733449A (en) | 1995-12-08 | 1998-03-31 | Orbital Biosciences, Llc | Microconcentrator device |
| DE19702907A1 (de) * | 1997-01-28 | 1998-07-30 | Boehringer Mannheim Gmbh | Verfahren und Vorrichtung zur Reinigung von Nukleinsäuren |
| DE19725190A1 (de) * | 1997-06-14 | 1998-12-17 | Innova Gmbh | Vorrichtungen mit integrierten Elektroden aus elektrisch leitfähigen Kunststoffen |
| EP1027145A4 (en) * | 1997-09-17 | 2004-08-25 | Gentra Systems Inc | APPARATUS AND METHODS FOR ISOLATING NUCLEIC ACID |
-
1997
- 1997-01-28 DE DE19702907A patent/DE19702907A1/de not_active Withdrawn
-
1998
- 1998-01-26 EP EP98904143A patent/EP0964934A1/de not_active Withdrawn
- 1998-01-26 WO PCT/EP1998/000408 patent/WO1998032877A1/de not_active Ceased
- 1998-01-26 US US09/355,365 patent/US6720417B1/en not_active Expired - Fee Related
- 1998-01-26 AU AU62132/98A patent/AU6213298A/en not_active Abandoned
- 1998-01-26 JP JP53160798A patent/JP2001511644A/ja not_active Withdrawn
-
2004
- 2004-02-25 US US10/786,835 patent/US20040166524A1/en not_active Abandoned
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004329213A (ja) * | 2003-05-01 | 2004-11-25 | Veridex Llc | 細胞および組織からのｒｎａ迅速抽出 |
| JP2011115173A (ja) * | 2003-05-01 | 2011-06-16 | Veridex Llc | 細胞および組織からのｒｎａ迅速抽出 |
| WO2008075501A1 (ja) | 2006-12-19 | 2008-06-26 | Konica Minolta Medical & Graphic, Inc. | 回転式抽出容器、それを用いた細胞種の同定方法、遺伝子検出方法、及び自動核酸抽出装置 |
| JP2016524706A (ja) * | 2013-05-24 | 2016-08-18 | オッカム バイオラブス，インコーポレイティド | 核酸サンプルを回収するためのシステム及び方法 |
| US10370650B2 (en) | 2013-05-24 | 2019-08-06 | Occam Biolabs, Inc. | System and method for collecting a sample of nucleic acid |
| US10287570B2 (en) | 2014-11-21 | 2019-05-14 | Occam Biolabs, Inc. | System and method for collecting a sample of nucleic acid |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6213298A (en) | 1998-08-18 |
| EP0964934A1 (de) | 1999-12-22 |
| US6720417B1 (en) | 2004-04-13 |
| US20040166524A1 (en) | 2004-08-26 |
| WO1998032877A1 (de) | 1998-07-30 |
| DE19702907A1 (de) | 1998-07-30 |
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