JP2001511121A5 - - Google Patents

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Publication number
JP2001511121A5
JP2001511121A5 JP1998531108A JP53110898A JP2001511121A5 JP 2001511121 A5 JP2001511121 A5 JP 2001511121A5 JP 1998531108 A JP1998531108 A JP 1998531108A JP 53110898 A JP53110898 A JP 53110898A JP 2001511121 A5 JP2001511121 A5 JP 2001511121A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998531108A
Other languages
English (en)
Japanese (ja)
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JP2001511121A (ja
JP4216342B2 (ja
Filing date
Publication date
Priority claimed from IL11998997A external-priority patent/IL119989A0/xx
Application filed filed Critical
Publication of JP2001511121A publication Critical patent/JP2001511121A/ja
Publication of JP2001511121A5 publication Critical patent/JP2001511121A5/ja
Application granted granted Critical
Publication of JP4216342B2 publication Critical patent/JP4216342B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP53110898A 1997-01-10 1998-01-12 コポリマー1の摂取又は吸入を通じての多発性硬化症の治療 Expired - Lifetime JP4216342B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL11998997A IL119989A0 (en) 1997-01-10 1997-01-10 Pharmaceutical compositions for oral treatment of multiple sclerosis
IL119,989 1997-01-10
PCT/US1998/000375 WO1998030227A1 (en) 1997-01-10 1998-01-12 Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1

Publications (3)

Publication Number Publication Date
JP2001511121A JP2001511121A (ja) 2001-08-07
JP2001511121A5 true JP2001511121A5 (https=) 2005-09-08
JP4216342B2 JP4216342B2 (ja) 2009-01-28

Family

ID=11069682

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53110898A Expired - Lifetime JP4216342B2 (ja) 1997-01-10 1998-01-12 コポリマー1の摂取又は吸入を通じての多発性硬化症の治療

Country Status (18)

Country Link
EP (1) EP0975351B1 (https=)
JP (1) JP4216342B2 (https=)
KR (1) KR20000070058A (https=)
CN (1) CN100528222C (https=)
AT (1) ATE356608T1 (https=)
AU (1) AU737287B2 (https=)
BR (1) BRPI9807076B8 (https=)
CA (1) CA2277365C (https=)
CZ (1) CZ297983B6 (https=)
DE (1) DE69837324T2 (https=)
EA (1) EA003128B1 (https=)
HU (1) HU226612B1 (https=)
IL (2) IL119989A0 (https=)
NZ (1) NZ336690A (https=)
PL (1) PL193300B1 (https=)
SK (1) SK284029B6 (https=)
WO (1) WO1998030227A1 (https=)
ZA (1) ZA98214B (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
JP2003521448A (ja) * 1998-07-23 2003-07-15 ザ・プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 合成ペプチドおよび自己免疫疾患治療のための使用方法
WO2000005250A1 (en) 1998-07-23 2000-02-03 Yeda Research And Development Co., Ltd Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US6872739B1 (en) * 1999-06-04 2005-03-29 Vereniging Voor Christelijk Wetenshappelikjk Onderwijs Use of riluzole for the treatment of multiple sclerosis
EP1187612B1 (en) * 1999-06-04 2005-01-26 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Use of riluzole for the treatment of multiple sclerosis
US7022663B2 (en) 2000-02-18 2006-04-04 Yeda Research And Development Co., Ltd. Oral, nasal and pulmonary dosage formulations of copolymer 1
WO2001060392A1 (en) * 2000-02-18 2001-08-23 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Oral, nasal and pulmonary dosage formualtions of copolymer 1
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
CA2411536A1 (en) * 2000-06-05 2001-12-13 V. Wee Yong The use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2002076503A1 (en) 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
SI1459065T1 (sl) 2001-12-04 2010-11-30 Teva Pharma Postopki za merjenje potentnosti glatiramer acetata
PL215263B1 (pl) 2002-02-25 2013-11-29 Elan Pharm Inc Kompozycja do przewleklego leczenia patologicznego zapalenia i zastosowanie natalizumabu lub jego immunologicznie aktywnego fragmentu do wytwarzania leku
CA2514125A1 (en) * 2003-01-24 2004-08-12 Elan Pharmaceuticals, Inc. Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
WO2006029411A2 (en) 2004-09-09 2006-03-16 Yeda Research And Development Co. Ltd. Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof
ES2612001T4 (es) 2009-08-20 2018-02-07 Yeda Research & Development Company, Ltd. Terapia de baja frecuencia con acetato de glatirámero
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
MX2015004563A (es) 2012-10-10 2015-07-14 Teva Pharma Biomarcadores predictivos para respuesta clinica para acetato de glatiramero.
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
CN105884866B (zh) * 2015-01-26 2021-04-20 漳州未名博欣生物医药有限公司 格拉替雷的化学合成方法
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
CN112649537B (zh) * 2015-04-28 2024-03-29 深圳翰宇药业股份有限公司 多肽混合物高效液相色谱分析方法
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu) 2016-08-31 2025-07-28 Mapi Pharma Ltd Glatiramer-acetátot tartalmazó depórendszerek
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
JP2020525459A (ja) 2017-06-26 2020-08-27 アンスティテュ・パストゥール Hivリザーバーを排除し、ウイルス負荷を低減する処置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113812A (en) * 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
US5719296A (en) * 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins

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