JP2001508061A - キトサン−ゼラチンａ微粒子 - Google Patents

キトサン−ゼラチンａ微粒子

Info

Publication number
JP2001508061A
JP2001508061A JP53067598A JP53067598A JP2001508061A JP 2001508061 A JP2001508061 A JP 2001508061A JP 53067598 A JP53067598 A JP 53067598A JP 53067598 A JP53067598 A JP 53067598A JP 2001508061 A JP2001508061 A JP 2001508061A
Authority
JP
Japan
Prior art keywords
chitosan
composition
gelatin
therapeutic substance
microspheres
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP53067598A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001508061A5 (enExample
Inventor
ワット、ピーター、ジェームズ
イルム、リズベス
Original Assignee
ウエスト・ファーマシュティカル・サービス・ドラッグ・デリバリー・エンド・クリニカル・リサーチ・センター・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ウエスト・ファーマシュティカル・サービス・ドラッグ・デリバリー・エンド・クリニカル・リサーチ・センター・リミテッド filed Critical ウエスト・ファーマシュティカル・サービス・ドラッグ・デリバリー・エンド・クリニカル・リサーチ・センター・リミテッド
Publication of JP2001508061A publication Critical patent/JP2001508061A/ja
Publication of JP2001508061A5 publication Critical patent/JP2001508061A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP53067598A 1997-01-14 1998-01-14 キトサン−ゼラチンａ微粒子 Ceased JP2001508061A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9700624.1 1997-01-14
GBGB9700624.1A GB9700624D0 (en) 1997-01-14 1997-01-14 Drug delivery composition
PCT/GB1998/000108 WO1998030207A1 (en) 1997-01-14 1998-01-14 Chitosan-gelatin a microparticles

Publications (2)

Publication Number Publication Date
JP2001508061A true JP2001508061A (ja) 2001-06-19
JP2001508061A5 JP2001508061A5 (enExample) 2005-09-08

Family

ID=10805925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53067598A Ceased JP2001508061A (ja) 1997-01-14 1998-01-14 キトサン−ゼラチンａ微粒子

Country Status (15)

Country Link
US (1) US6465626B1 (enExample)
EP (1) EP0952822B1 (enExample)
JP (1) JP2001508061A (enExample)
AT (1) ATE235889T1 (enExample)
AU (1) AU725460B2 (enExample)
CA (1) CA2275717C (enExample)
DE (1) DE69812887T2 (enExample)
DK (1) DK0952822T3 (enExample)
ES (1) ES2200306T3 (enExample)
GB (2) GB9700624D0 (enExample)
NO (1) NO993195L (enExample)
NZ (1) NZ335815A (enExample)
PT (1) PT952822E (enExample)
WO (1) WO1998030207A1 (enExample)
ZA (1) ZA98273B (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503432A (ja) * 1999-07-02 2003-01-28 コグニス・イベリア・ソシエダッド・リミターダ マイクロカプセル−ｉｉ
JP2006525354A (ja) * 2003-05-01 2006-11-09 アルキメデス・ディヴェロップメント・リミテッド Ｌｈ−ｒｈアナログロイプロイドの経鼻投与
JP2007006849A (ja) * 2005-07-04 2007-01-18 Japan Science & Technology Agency ６−アミノ−６−デオキシキトサン誘導体から成る核酸導入剤
JP5415769B2 (ja) * 2006-12-26 2014-02-12 株式会社新日本科学 経鼻投与用製剤
JP2014510778A (ja) * 2011-04-11 2014-05-01 アヤンダ グループ エーエス 経口医薬分散組成物
JP2017019847A (ja) * 2010-04-14 2017-01-26 アヤンダ グループ エーエス 経口医薬分散組成物
JP2022528430A (ja) * 2019-03-22 2022-06-10 ノー－キューティカルズ・ビー．ブイ． 一酸化窒素ドナー（ｎｏドナー）として使用するためのキトサン硝酸塩

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US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
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US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
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US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
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US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
AU2001267011B2 (en) * 2000-06-21 2006-02-02 Cubist Pharmaceuticals, Inc. Compositions and methods to improve the oral absorption of antimicrobial agents
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EP1443944A1 (de) * 2001-11-12 2004-08-11 Johannes Reinmüller Pharmazeutische anwendungen von hyaluronsäure-präparaten
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EP1638491A4 (en) * 2003-06-16 2008-05-28 Univ Loma Linda Med ABLEABLE MULTIFUNCTIONAL HEMOSTASIS
US20050118238A1 (en) * 2003-06-16 2005-06-02 Zhu Yong H. Deployable hemostatic agent
CN100381110C (zh) * 2003-06-16 2008-04-16 洛马林达大学医学中心 可展开的止血剂
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JP4694214B2 (ja) * 2004-02-20 2011-06-08 ローム株式会社 比較器、ａｄ変換回路、半導体装置、および撮像装置
EP1718147B1 (en) 2004-02-23 2012-03-28 Loma Linda University Medical Center Hemostatic agent for topical and internal use
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US7740883B2 (en) * 2004-03-28 2010-06-22 University Of Debrecen Nanoparticles from chitosan
JP2007536259A (ja) * 2004-05-06 2007-12-13 イヴレア ファーマスーティカルズ インコーポレイテッド 活性薬剤の送達のための粒子
EP1758633B1 (en) * 2004-05-13 2015-03-18 Medtronic Vascular, Inc. Methods for compounding a therapeutic agent to the adventitia of a vessel
GB0416328D0 (en) * 2004-07-21 2004-08-25 Univ Cardiff Use of dry powder compositions for pulmonary delivery
WO2006016530A1 (ja) 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
DE102004059792A1 (de) * 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
EP1824459A1 (en) * 2004-12-17 2007-08-29 Medipol S.A. Hydrophilic particles based on cationic chitosan derivatives
US20090136505A1 (en) * 2005-02-23 2009-05-28 Johanna Bentz Intranasal Administration of Active Agents to the Central Nervous System
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US8303972B2 (en) * 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
NZ580951A (en) * 2005-04-29 2011-06-30 Cubist Pharm Inc Therapeutic compositions
AU2007285472B2 (en) * 2006-03-30 2013-10-24 Engene, Inc. Non-viral compositions and methods for transfecting gut cells in vivo
CA2848648C (en) * 2006-06-02 2017-10-10 Synedgen, Inc. Chitosan-derivative compounds and methods of controlling microbial populations
WO2007148048A1 (en) 2006-06-20 2007-12-27 Cmp Therapeutics Limited Compositions comprising chitin microparticles and their medical uses
US20080248508A1 (en) * 2006-08-17 2008-10-09 Shenda Baker Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
US8741326B2 (en) * 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
EP2112923A1 (en) 2007-01-22 2009-11-04 Targacept Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
GB0716907D0 (en) * 2007-08-31 2007-10-10 Archimedes Dev Ltd Pharmaceutical powder compositions
GB0722507D0 (en) * 2007-11-19 2007-12-27 Zhao Xiaobin Hyaluronic acid personal lubricant
DE102008059857A1 (de) * 2008-12-01 2010-06-02 Forschungsinstitut für Leder und Kunststoffbahnen gGmbH Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen
US9101539B2 (en) 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
US8827946B2 (en) 2009-07-31 2014-09-09 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
WO2011066471A1 (en) 2009-11-25 2011-06-03 Loma Linda University Medical Center Chitosan-based hemostatic textile
US8968790B2 (en) * 2011-12-09 2015-03-03 Shaker A. Mousa Nanoformulation of vitamin D derivatives and/or vitamin D metabolites
FR2991172A1 (fr) * 2012-06-01 2013-12-06 Galderma Res & Dev Compositions pharmaceutiques topiques comprenant des microcapsules
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US9878000B2 (en) 2012-06-20 2018-01-30 University Of Waterloo Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof
US9259357B2 (en) 2014-04-16 2016-02-16 Loma Linda University Composition, preparation, and use of chitosan shards for biomedical applications
US10182993B2 (en) 2015-04-06 2019-01-22 Patheon Softgels Inc. Compositions for colonic delivery of drugs
US12427224B1 (en) 2015-10-15 2025-09-30 Oceanit Laboratories, Inc. Hemostatic microparticles and dressing
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KR20200125632A (ko) * 2018-02-26 2020-11-04 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. 분말 제제, 카트리지 및 디바이스
IL279713B2 (en) 2018-06-27 2025-01-01 Bioxcel Therapeutics Inc Dexmedetomidine-containing layer compositions and methods for their production
EP3999058A4 (en) 2019-07-19 2023-05-03 Bioxcel Therapeutics, Inc. TREATMENT SCHEMES FOR NON-SEDATING DEXMEDETOMIDIN
CN112370437B (zh) * 2020-10-20 2022-10-21 好医生药业集团有限公司 一种阿莫西林胶囊及其制备方法
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
CN118304423B (zh) * 2023-05-25 2024-10-11 无锡市第二人民医院 多层级壳聚糖明胶颗粒载P4HA1 siRNA通过抑制细胞EMT治疗脑胶质瘤的研究

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003503432A (ja) * 1999-07-02 2003-01-28 コグニス・イベリア・ソシエダッド・リミターダ マイクロカプセル−ｉｉ
JP4822642B2 (ja) * 1999-07-02 2011-11-24 コグニス・アイピー・マネージメント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング マイクロカプセル−ｉｉ
JP2006525354A (ja) * 2003-05-01 2006-11-09 アルキメデス・ディヴェロップメント・リミテッド Ｌｈ−ｒｈアナログロイプロイドの経鼻投与
JP2007006849A (ja) * 2005-07-04 2007-01-18 Japan Science & Technology Agency ６−アミノ−６−デオキシキトサン誘導体から成る核酸導入剤
JP5415769B2 (ja) * 2006-12-26 2014-02-12 株式会社新日本科学 経鼻投与用製剤
JP2017019847A (ja) * 2010-04-14 2017-01-26 アヤンダ グループ エーエス 経口医薬分散組成物
US10966926B2 (en) 2010-04-14 2021-04-06 Vitux Group As Oral pharmaceutical dispersion compositions
JP2014510778A (ja) * 2011-04-11 2014-05-01 アヤンダ グループ エーエス 経口医薬分散組成物
JP2022528430A (ja) * 2019-03-22 2022-06-10 ノー－キューティカルズ・ビー．ブイ． 一酸化窒素ドナー（ｎｏドナー）として使用するためのキトサン硝酸塩
JP7618241B2 (ja) 2019-03-22 2025-01-21 ノー－キューティカルズ・ビー．ブイ． 一酸化窒素ドナー（ｎｏドナー）として使用するためのキトサン硝酸塩

Also Published As

Publication number Publication date
PT952822E (pt) 2003-08-29
EP0952822B1 (en) 2003-04-02
DE69812887D1 (de) 2003-05-08
GB9700624D0 (en) 1997-03-05
CA2275717C (en) 2007-09-11
ES2200306T3 (es) 2004-03-01
NO993195D0 (no) 1999-06-28
US6465626B1 (en) 2002-10-15
DE69812887T2 (de) 2003-12-18
AU725460B2 (en) 2000-10-12
GB9916018D0 (en) 1999-09-08
EP0952822A1 (en) 1999-11-03
NZ335815A (en) 2001-03-30
WO1998030207A1 (en) 1998-07-16
ZA98273B (en) 1999-07-13
GB2335357A (en) 1999-09-22
CA2275717A1 (en) 1998-07-16
NO993195L (no) 1999-06-28
ATE235889T1 (de) 2003-04-15
DK0952822T3 (da) 2003-07-21
GB2335357B (en) 2000-12-13
AU5568998A (en) 1998-08-03

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