JP2001506606A5 - - Google Patents
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- Publication number
- JP2001506606A5 JP2001506606A5 JP1998524829A JP52482998A JP2001506606A5 JP 2001506606 A5 JP2001506606 A5 JP 2001506606A5 JP 1998524829 A JP1998524829 A JP 1998524829A JP 52482998 A JP52482998 A JP 52482998A JP 2001506606 A5 JP2001506606 A5 JP 2001506606A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3182296P | 1996-11-26 | 1996-11-26 | |
| US60/031,822 | 1996-11-26 | ||
| PCT/US1997/021649 WO1998023565A2 (en) | 1996-11-26 | 1997-11-26 | Aminoguanidines and alkoxyguanidines as protease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001506606A JP2001506606A (ja) | 2001-05-22 |
| JP2001506606A5 true JP2001506606A5 (https=) | 2005-08-11 |
Family
ID=21861593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52482998A Ceased JP2001506606A (ja) | 1996-11-26 | 1997-11-26 | プロテアーゼインヒビターとしてのアミノグアニジンおよびアルコキシグアニジン |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US6235778B1 (https=) |
| EP (1) | EP0944590B1 (https=) |
| JP (1) | JP2001506606A (https=) |
| KR (1) | KR100587546B1 (https=) |
| CN (1) | CN1237961A (https=) |
| AR (1) | AR008327A1 (https=) |
| AT (1) | ATE214693T1 (https=) |
| AU (1) | AU725058B2 (https=) |
| BR (1) | BR9713328A (https=) |
| CA (1) | CA2273023C (https=) |
| DE (1) | DE69711222T2 (https=) |
| DK (1) | DK0944590T3 (https=) |
| EA (1) | EA002740B1 (https=) |
| ES (1) | ES2174309T3 (https=) |
| HU (1) | HUP0000733A3 (https=) |
| IL (1) | IL130102A (https=) |
| IN (1) | IN190530B (https=) |
| NO (1) | NO314140B1 (https=) |
| NZ (1) | NZ336093A (https=) |
| PL (1) | PL333434A1 (https=) |
| PT (1) | PT944590E (https=) |
| TW (1) | TW499412B (https=) |
| WO (1) | WO1998023565A2 (https=) |
| ZA (1) | ZA9710646B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI222441B (en) | 1997-11-26 | 2004-10-21 | Dimensional Pharm Inc | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors |
| US6344486B1 (en) | 1998-04-03 | 2002-02-05 | 3-Dimensional Pharmaceuticals, Inc. | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors |
| WO1999055355A1 (en) | 1998-04-24 | 1999-11-04 | 3-Dimensional Pharmaceuticals, Inc. | Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors |
| JP4554077B2 (ja) | 1998-06-11 | 2010-09-29 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | ピラジノンプロテアーゼインヒビター |
| AU3731400A (en) | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Methods and compositions useful in inhibiting apoptosis |
| US6544541B1 (en) * | 1999-06-02 | 2003-04-08 | Cardiovascular Solutions, Inc. | Devices and compounds for treating arterial restenosis |
| CA2415932A1 (en) | 2000-07-17 | 2002-01-24 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine pyrazinones as protease inhibitors |
| CA2417914A1 (en) | 2000-08-04 | 2002-02-14 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine protease inhibitors |
| KR100371008B1 (ko) * | 2000-08-05 | 2003-02-06 | 조동련 | 혈소판 응집 억제제 부착 스텐트의 그 제조 방법 |
| UA75093C2 (en) * | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| EP1419172A4 (en) * | 2001-08-03 | 2007-10-03 | Univ Leland Stanford Junior | BIDIRECTIONAL SYNTHESIS OF OLIGOGUANIDINTRANSPORTING MEANS |
| US20060264608A1 (en) * | 2001-08-03 | 2006-11-23 | Wender Paul A | Bi-directional synthesis of oligoguanidine transport agents |
| AU2003234382B2 (en) * | 2002-05-13 | 2010-07-08 | Becton, Dickinson And Company | Protease inhibitor sample collection system |
| US7850970B2 (en) | 2003-08-26 | 2010-12-14 | The Regents Of The University Of Colorado | Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections |
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| JP2008544987A (ja) * | 2005-06-30 | 2008-12-11 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | 殺虫性の（二置換プロペニル）フェニルアルキル置換複素環式環を調製するための改善された方法 |
| JP2009521472A (ja) * | 2005-12-22 | 2009-06-04 | シェーリング コーポレイション | 心肺手術の合併症の予防としてのトロンビンレセプターアンタゴニスト |
| TWI618544B (zh) | 2006-12-26 | 2018-03-21 | 藍瑟斯醫學影像公司 | 使心臟神經分布顯像之配位體 |
| WO2010134345A1 (ja) * | 2009-05-20 | 2010-11-25 | 積水メディカル株式会社 | 血液凝固時間延長剤 |
| AU2011253052B2 (en) | 2010-05-11 | 2015-05-14 | Lantheus Medical Imaging, Inc. | Compositions, methods and systems for the synthesis and use of imaging agents |
| CA2824599C (en) * | 2010-12-31 | 2020-03-10 | Astrazeneca Uk Limited | Arginase inhibitors and methods of use thereof |
| JP2014515352A (ja) | 2011-05-17 | 2014-06-30 | ベリコ メディカル インコーポレイティッド | シアリダーゼ阻害剤を用いた血小板の保存の改善法 |
| US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
| CN102850451B (zh) * | 2011-06-29 | 2014-05-07 | 辽宁诺康生物制药有限责任公司 | 具有抑制纤溶酶活性的重组textilinin-1及其制备方法和应用 |
| CA3194125A1 (en) | 2012-04-12 | 2013-10-17 | The Trustees Of The University Of Pennsylvania | Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
| EP2903430A1 (en) | 2012-10-05 | 2015-08-12 | Velico Medical, Inc. | Platelet additive solution having a beta-galactosidase inhibitor |
| WO2014120886A1 (en) | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
| US9555016B2 (en) | 2013-06-10 | 2017-01-31 | Covidien Lp | Lytic agents for use in treating intravascular clots |
| CN107382869A (zh) * | 2017-08-01 | 2017-11-24 | 李凯 | 一种治疗中风后遗症的化合物及制备方法和应用 |
| GB2568550B (en) * | 2017-11-21 | 2021-06-30 | Univ Cape Town | Method of synthesising 6-deoxy-6-amino-ß-d-glucopyranoside-containing polymers |
| WO2022016345A1 (zh) * | 2020-07-20 | 2022-01-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种组合物的血小板解聚用途、解聚试剂及解聚方法 |
| GB202108544D0 (en) * | 2021-06-15 | 2021-07-28 | Z Factor Ltd | Compounds and their use for the treatment of alpha1-antitrypsin deficiency |
| CN115772196A (zh) * | 2021-09-08 | 2023-03-10 | 赛诺哈勃药业（成都）有限公司 | 一种纤溶酶抑制活性的化合物、其制备方法及应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3131218A (en) * | 1961-02-15 | 1964-04-28 | Smith Kline French Lab | N-amino guanidine derivatives |
| US3271448A (en) | 1961-11-21 | 1966-09-06 | Pfizer & Co C | Phenoxyalkyl aminoguanidines |
| BE663481A (https=) * | 1964-05-05 | |||
| US3413303A (en) * | 1965-09-27 | 1968-11-26 | Ciba Geigy Corp | Aralkenyloxyguanidines |
| JPS57178739A (en) | 1981-04-27 | 1982-11-04 | Mitsubishi Heavy Ind Ltd | Bead supplying device for tire molding machine |
| US4429146A (en) * | 1982-04-15 | 1984-01-31 | Gaf Corporation | Substituted diphenyl ether herbicides and process for use |
| JPS6229566A (ja) | 1985-07-30 | 1987-02-07 | Taiyo Yakuhin Kogyo Kk | 新規グアニジノメチル安息香酸誘導体 |
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| EP0604022A1 (en) | 1992-12-22 | 1994-06-29 | Advanced Cardiovascular Systems, Inc. | Multilayered biodegradable stent and method for its manufacture |
| TW257757B (https=) | 1993-03-03 | 1995-09-21 | Boehringer Mannheim Gmbh | |
| GB9318637D0 (en) | 1993-09-08 | 1993-10-27 | Ferring Res Ltd | Enzyme inhibitors |
| US6087479A (en) | 1993-09-17 | 2000-07-11 | Nitromed, Inc. | Localized use of nitric oxide-adducts to prevent internal tissue damage |
| US5466811A (en) | 1994-07-18 | 1995-11-14 | Merck & Co., Inc. | Dioxolenylmethyl carbamates pro moieties for amine drugs |
| US5643580A (en) | 1994-10-17 | 1997-07-01 | Surface Genesis, Inc. | Biocompatible coating, medical device using the same and methods |
| ES2235174T3 (es) | 1994-10-17 | 2005-07-01 | Kabushikikaisha Igaki Iryo Sekkei | Stent liberador de medicamento. |
| US5637113A (en) | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
| DE19514104C2 (de) | 1995-04-13 | 1997-05-28 | Behringwerke Ag | Beschichtung für in den Blutstrom oder in das Gewebe des menschlichen Körpers einbringbares Biomaterial |
| HU211262A9 (hu) | 1995-05-12 | 1995-11-28 | Hoechst Ag | Benzoil-guanidinek |
| WO1997011693A1 (en) | 1995-09-29 | 1997-04-03 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| US5792769A (en) | 1995-09-29 | 1998-08-11 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| GB9525620D0 (en) | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
| WO1997024135A1 (en) | 1995-12-29 | 1997-07-10 | 3-Dimensional Pharmaceuticals, Inc. | Amidino protease inhibitors |
| US5891909A (en) | 1996-03-29 | 1999-04-06 | 3-Dimensional Pharmaceuticals, Inc. | Amidinohydrazones as protease inhibitors |
| SE9602646D0 (sv) | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically-useful compounds |
-
1997
- 1997-11-25 TW TW086117721A patent/TW499412B/zh not_active IP Right Cessation
- 1997-11-26 US US08/979,234 patent/US6235778B1/en not_active Expired - Lifetime
- 1997-11-26 EP EP97948537A patent/EP0944590B1/en not_active Expired - Lifetime
- 1997-11-26 ZA ZA9710646A patent/ZA9710646B/xx unknown
- 1997-11-26 WO PCT/US1997/021649 patent/WO1998023565A2/en not_active Ceased
- 1997-11-26 HU HU0000733A patent/HUP0000733A3/hu unknown
- 1997-11-26 AR ARP970105565A patent/AR008327A1/es active IP Right Grant
- 1997-11-26 DE DE69711222T patent/DE69711222T2/de not_active Expired - Fee Related
- 1997-11-26 IL IL13010297A patent/IL130102A/xx not_active IP Right Cessation
- 1997-11-26 ES ES97948537T patent/ES2174309T3/es not_active Expired - Lifetime
- 1997-11-26 AU AU54584/98A patent/AU725058B2/en not_active Ceased
- 1997-11-26 BR BR9713328-0A patent/BR9713328A/pt not_active Application Discontinuation
- 1997-11-26 EA EA199900544A patent/EA002740B1/ru not_active IP Right Cessation
- 1997-11-26 PL PL97333434A patent/PL333434A1/xx not_active Application Discontinuation
- 1997-11-26 IN IN2232CA1997 patent/IN190530B/en unknown
- 1997-11-26 KR KR1019997004642A patent/KR100587546B1/ko not_active Expired - Fee Related
- 1997-11-26 JP JP52482998A patent/JP2001506606A/ja not_active Ceased
- 1997-11-26 AT AT97948537T patent/ATE214693T1/de not_active IP Right Cessation
- 1997-11-26 NZ NZ336093A patent/NZ336093A/xx unknown
- 1997-11-26 CN CN97199940A patent/CN1237961A/zh active Pending
- 1997-11-26 CA CA002273023A patent/CA2273023C/en not_active Expired - Fee Related
- 1997-11-26 DK DK97948537T patent/DK0944590T3/da active
- 1997-11-26 PT PT97948537T patent/PT944590E/pt unknown
-
1999
- 1999-05-25 NO NO19992512A patent/NO314140B1/no unknown
-
2000
- 2000-11-28 US US09/722,363 patent/US6638931B1/en not_active Expired - Lifetime
-
2001
- 2001-03-16 US US09/809,293 patent/US6518310B2/en not_active Expired - Lifetime
-
2003
- 2003-02-06 US US10/359,078 patent/US6706765B2/en not_active Expired - Lifetime
- 2003-04-22 US US10/419,972 patent/US6730783B2/en not_active Expired - Lifetime