JP2001506606A5 - - Google Patents
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- Publication number
- JP2001506606A5 JP2001506606A5 JP1998524829A JP52482998A JP2001506606A5 JP 2001506606 A5 JP2001506606 A5 JP 2001506606A5 JP 1998524829 A JP1998524829 A JP 1998524829A JP 52482998 A JP52482998 A JP 52482998A JP 2001506606 A5 JP2001506606 A5 JP 2001506606A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3182296P | 1996-11-26 | 1996-11-26 | |
| US60/031,822 | 1996-11-26 | ||
| PCT/US1997/021649 WO1998023565A2 (en) | 1996-11-26 | 1997-11-26 | Aminoguanidines and alkoxyguanidines as protease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001506606A JP2001506606A (ja) | 2001-05-22 |
| JP2001506606A5 true JP2001506606A5 (https=) | 2005-08-11 |
Family
ID=21861593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52482998A Ceased JP2001506606A (ja) | 1996-11-26 | 1997-11-26 | プロテアーゼインヒビターとしてのアミノグアニジンおよびアルコキシグアニジン |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US6235778B1 (https=) |
| EP (1) | EP0944590B1 (https=) |
| JP (1) | JP2001506606A (https=) |
| KR (1) | KR100587546B1 (https=) |
| CN (1) | CN1237961A (https=) |
| AR (1) | AR008327A1 (https=) |
| AT (1) | ATE214693T1 (https=) |
| AU (1) | AU725058B2 (https=) |
| BR (1) | BR9713328A (https=) |
| CA (1) | CA2273023C (https=) |
| DE (1) | DE69711222T2 (https=) |
| DK (1) | DK0944590T3 (https=) |
| EA (1) | EA002740B1 (https=) |
| ES (1) | ES2174309T3 (https=) |
| HU (1) | HUP0000733A3 (https=) |
| IL (1) | IL130102A (https=) |
| IN (1) | IN190530B (https=) |
| NO (1) | NO314140B1 (https=) |
| NZ (1) | NZ336093A (https=) |
| PL (1) | PL333434A1 (https=) |
| PT (1) | PT944590E (https=) |
| TW (1) | TW499412B (https=) |
| WO (1) | WO1998023565A2 (https=) |
| ZA (1) | ZA9710646B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999026926A1 (en) | 1997-11-26 | 1999-06-03 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors |
| US6344486B1 (en) | 1998-04-03 | 2002-02-05 | 3-Dimensional Pharmaceuticals, Inc. | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors |
| AU750561B2 (en) | 1998-04-24 | 2002-07-25 | 3-Dimensional Pharmaceuticals, Inc. | Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors |
| NZ508669A (en) | 1998-06-11 | 2003-06-30 | Dimensional Pharm Inc | Pyrazinone protease inhibitors |
| AU3731400A (en) | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Methods and compositions useful in inhibiting apoptosis |
| US6544541B1 (en) * | 1999-06-02 | 2003-04-08 | Cardiovascular Solutions, Inc. | Devices and compounds for treating arterial restenosis |
| US6476016B2 (en) | 2000-07-17 | 2002-11-05 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine pyrazinones as protease inhibitors |
| MXPA03000963A (es) | 2000-08-04 | 2004-04-05 | Dimensional Pharm Inc | Inhibidores de oxiguanidina ciclica proteasa. |
| KR100371008B1 (ko) * | 2000-08-05 | 2003-02-06 | 조동련 | 혈소판 응집 억제제 부착 스텐트의 그 제조 방법 |
| UA75093C2 (en) | 2000-10-06 | 2006-03-15 | Dimensional Pharm Inc | Aminopyridinyl-,aminoguanidinyl-, and alkoxyguanidinesubstituted phenylsubstituted phenylacetamides as protease inhibitors |
| CA2455951A1 (en) * | 2001-08-03 | 2003-02-20 | The Board Of Trustees Of The Leland Stanford Junior University | Bi-directional synthesis of oligoguanidine transport agents |
| US20060264608A1 (en) * | 2001-08-03 | 2006-11-23 | Wender Paul A | Bi-directional synthesis of oligoguanidine transport agents |
| JP4496407B2 (ja) * | 2002-05-13 | 2010-07-07 | ベクトン・ディキンソン・アンド・カンパニー | プロテアーゼ阻害剤試料採取システム |
| US7850970B2 (en) | 2003-08-26 | 2010-12-14 | The Regents Of The University Of Colorado | Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections |
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| CN101213172A (zh) * | 2005-06-30 | 2008-07-02 | 拜尔农作物科学股份公司 | 具有杀虫作用的(二取代丙烯基)苯基烷基取代的杂环类化合物的改良的制备方法 |
| EP1971336A2 (en) * | 2005-12-22 | 2008-09-24 | Shering Corporation | Thrombin receptor antagonists as phophylaxis to complications from cardiopulmonary surgery |
| ES2405655T3 (es) | 2006-12-26 | 2013-05-31 | Lantheus Medical Imaging, Inc. | N-[3-bromo-4-(3-[18F]fluoropropoxi)-bencil]-guanidina para la formación de imágenes de la inervación cardíaca |
| EP2434290B1 (en) * | 2009-05-20 | 2016-02-10 | Sekisui Medical Co., Ltd. | Blood coagulation time prolonging agent |
| ES2763815T3 (es) | 2010-05-11 | 2020-06-01 | Lantheus Medical Imaging Inc | Composiciones, métodos y sistemas para la síntesis y uso de agentes de formación de imágenes |
| CA2824599C (en) * | 2010-12-31 | 2020-03-10 | Astrazeneca Uk Limited | Arginase inhibitors and methods of use thereof |
| WO2012158983A2 (en) | 2011-05-17 | 2012-11-22 | Qiyong Peter Liu | Improved platelet storage using a sialidase inhibitor |
| US9788539B2 (en) | 2011-05-17 | 2017-10-17 | Velico Medical, Inc. | Platelet protection solution having beta-galactosidase and sialidase inhibitors |
| CN102850451B (zh) * | 2011-06-29 | 2014-05-07 | 辽宁诺康生物制药有限责任公司 | 具有抑制纤溶酶活性的重组textilinin-1及其制备方法和应用 |
| CA3194125A1 (en) | 2012-04-12 | 2013-10-17 | The Trustees Of The University Of Pennsylvania | Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
| EP2903430A1 (en) | 2012-10-05 | 2015-08-12 | Velico Medical, Inc. | Platelet additive solution having a beta-galactosidase inhibitor |
| WO2014120886A1 (en) | 2013-01-30 | 2014-08-07 | Velico Medical, Inc. | Platelet additive solution having a self-assembling hydrogel-forming peptide |
| US9555016B2 (en) | 2013-06-10 | 2017-01-31 | Covidien Lp | Lytic agents for use in treating intravascular clots |
| CN107382869A (zh) * | 2017-08-01 | 2017-11-24 | 李凯 | 一种治疗中风后遗症的化合物及制备方法和应用 |
| GB2568550B (en) * | 2017-11-21 | 2021-06-30 | Univ Cape Town | Method of synthesising 6-deoxy-6-amino-ß-d-glucopyranoside-containing polymers |
| EP4183777A4 (en) * | 2020-07-20 | 2023-11-29 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd | USE OF A PLATELET DISAGGREGATION COMPOSITION, DISAGGREGATION REAGENT AND DISAGGREGATION METHOD |
| GB202108544D0 (en) * | 2021-06-15 | 2021-07-28 | Z Factor Ltd | Compounds and their use for the treatment of alpha1-antitrypsin deficiency |
| CN115772196A (zh) * | 2021-09-08 | 2023-03-10 | 赛诺哈勃药业（成都）有限公司 | 一种纤溶酶抑制活性的化合物、其制备方法及应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3131218A (en) * | 1961-02-15 | 1964-04-28 | Smith Kline French Lab | N-amino guanidine derivatives |
| US3271448A (en) | 1961-11-21 | 1966-09-06 | Pfizer & Co C | Phenoxyalkyl aminoguanidines |
| BE663481A (https=) | 1964-05-05 | |||
| US3413303A (en) * | 1965-09-27 | 1968-11-26 | Ciba Geigy Corp | Aralkenyloxyguanidines |
| JPS57178739A (en) | 1981-04-27 | 1982-11-04 | Mitsubishi Heavy Ind Ltd | Bead supplying device for tire molding machine |
| US4429146A (en) * | 1982-04-15 | 1984-01-31 | Gaf Corporation | Substituted diphenyl ether herbicides and process for use |
| JPS6229566A (ja) | 1985-07-30 | 1987-02-07 | Taiyo Yakuhin Kogyo Kk | 新規グアニジノメチル安息香酸誘導体 |
| DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| EP0604022A1 (en) | 1992-12-22 | 1994-06-29 | Advanced Cardiovascular Systems, Inc. | Multilayered biodegradable stent and method for its manufacture |
| TW257757B (https=) | 1993-03-03 | 1995-09-21 | Boehringer Mannheim Gmbh | |
| GB9318637D0 (en) | 1993-09-08 | 1993-10-27 | Ferring Res Ltd | Enzyme inhibitors |
| US6087479A (en) | 1993-09-17 | 2000-07-11 | Nitromed, Inc. | Localized use of nitric oxide-adducts to prevent internal tissue damage |
| US5466811A (en) | 1994-07-18 | 1995-11-14 | Merck & Co., Inc. | Dioxolenylmethyl carbamates pro moieties for amine drugs |
| US5643580A (en) | 1994-10-17 | 1997-07-01 | Surface Genesis, Inc. | Biocompatible coating, medical device using the same and methods |
| AU699821B2 (en) | 1994-10-17 | 1998-12-17 | Kabushikikaisha Igaki Iryo Sekkei | Stent for liberating drug |
| US5637113A (en) | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
| DE19514104C2 (de) | 1995-04-13 | 1997-05-28 | Behringwerke Ag | Beschichtung für in den Blutstrom oder in das Gewebe des menschlichen Körpers einbringbares Biomaterial |
| HU211262A9 (hu) | 1995-05-12 | 1995-11-28 | Hoechst Ag | Benzoil-guanidinek |
| US5792769A (en) | 1995-09-29 | 1998-08-11 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| CA2233344A1 (en) | 1995-09-29 | 1997-04-03 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| GB9525620D0 (en) | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
| EP0883405B1 (en) | 1995-12-29 | 2004-02-25 | 3-Dimensional Pharmaceuticals, Inc. | Amidino protease inhibitors |
| CA2250426C (en) | 1996-03-29 | 2006-05-02 | 3-Dimensional Pharmaceuticals, Inc. | Amidinohydrazones as protease inhibitors |
| SE9602646D0 (sv) | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically-useful compounds |
-
1997
- 1997-11-25 TW TW086117721A patent/TW499412B/zh not_active IP Right Cessation
- 1997-11-26 AR ARP970105565A patent/AR008327A1/es active IP Right Grant
- 1997-11-26 EP EP97948537A patent/EP0944590B1/en not_active Expired - Lifetime
- 1997-11-26 IL IL13010297A patent/IL130102A/xx not_active IP Right Cessation
- 1997-11-26 BR BR9713328-0A patent/BR9713328A/pt not_active Application Discontinuation
- 1997-11-26 NZ NZ336093A patent/NZ336093A/xx unknown
- 1997-11-26 ES ES97948537T patent/ES2174309T3/es not_active Expired - Lifetime
- 1997-11-26 KR KR1019997004642A patent/KR100587546B1/ko not_active Expired - Fee Related
- 1997-11-26 AT AT97948537T patent/ATE214693T1/de not_active IP Right Cessation
- 1997-11-26 WO PCT/US1997/021649 patent/WO1998023565A2/en not_active Ceased
- 1997-11-26 US US08/979,234 patent/US6235778B1/en not_active Expired - Lifetime
- 1997-11-26 EA EA199900544A patent/EA002740B1/ru not_active IP Right Cessation
- 1997-11-26 AU AU54584/98A patent/AU725058B2/en not_active Ceased
- 1997-11-26 CA CA002273023A patent/CA2273023C/en not_active Expired - Fee Related
- 1997-11-26 PT PT97948537T patent/PT944590E/pt unknown
- 1997-11-26 ZA ZA9710646A patent/ZA9710646B/xx unknown
- 1997-11-26 JP JP52482998A patent/JP2001506606A/ja not_active Ceased
- 1997-11-26 HU HU0000733A patent/HUP0000733A3/hu unknown
- 1997-11-26 DK DK97948537T patent/DK0944590T3/da active
- 1997-11-26 IN IN2232CA1997 patent/IN190530B/en unknown
- 1997-11-26 PL PL97333434A patent/PL333434A1/xx not_active Application Discontinuation
- 1997-11-26 DE DE69711222T patent/DE69711222T2/de not_active Expired - Fee Related
- 1997-11-26 CN CN97199940A patent/CN1237961A/zh active Pending
-
1999
- 1999-05-25 NO NO19992512A patent/NO314140B1/no unknown
-
2000
- 2000-11-28 US US09/722,363 patent/US6638931B1/en not_active Expired - Lifetime
-
2001
- 2001-03-16 US US09/809,293 patent/US6518310B2/en not_active Expired - Lifetime
-
2003
- 2003-02-06 US US10/359,078 patent/US6706765B2/en not_active Expired - Lifetime
- 2003-04-22 US US10/419,972 patent/US6730783B2/en not_active Expired - Lifetime