JP2001503778A5 - - Google Patents

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Publication number
JP2001503778A5
JP2001503778A5 JP1998522867A JP52286798A JP2001503778A5 JP 2001503778 A5 JP2001503778 A5 JP 2001503778A5 JP 1998522867 A JP1998522867 A JP 1998522867A JP 52286798 A JP52286798 A JP 52286798A JP 2001503778 A5 JP2001503778 A5 JP 2001503778A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998522867A
Other languages
English (en)
Japanese (ja)
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JP2001503778A (ja
Filing date
Publication date
Priority claimed from US08/749,114 external-priority patent/US5780484A/en
Application filed filed Critical
Publication of JP2001503778A publication Critical patent/JP2001503778A/ja
Publication of JP2001503778A5 publication Critical patent/JP2001503778A5/ja
Pending legal-status Critical Current

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JP52286798A 1996-11-13 1997-11-13 神経栄養因子と組み合わせてfkbp12に関するアフィニティを有する化合物を用いて神経突起の成長を刺激する方法および組成物 Pending JP2001503778A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/749,114 US5780484A (en) 1996-11-13 1996-11-13 Methods for stimulating neurite growth with piperidine compounds
US08/749,114 1996-11-13
PCT/US1997/020868 WO1998020893A1 (en) 1996-11-13 1997-11-13 Methods and compositions for stimulating neurite growth using compounds with affinity for fkbp12 in combination with neurotrophic factors

Publications (2)

Publication Number Publication Date
JP2001503778A JP2001503778A (ja) 2001-03-21
JP2001503778A5 true JP2001503778A5 (https=) 2005-07-14

Family

ID=25012320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52286798A Pending JP2001503778A (ja) 1996-11-13 1997-11-13 神経栄養因子と組み合わせてfkbp12に関するアフィニティを有する化合物を用いて神経突起の成長を刺激する方法および組成物

Country Status (19)

Country Link
US (1) US5780484A (https=)
EP (2) EP1666053A1 (https=)
JP (1) JP2001503778A (https=)
KR (1) KR100537866B1 (https=)
CN (1) CN1168443C (https=)
AR (1) AR015105A1 (https=)
AU (1) AU741186B2 (https=)
BR (1) BR9713037A (https=)
CA (1) CA2270985A1 (https=)
CO (1) CO5080733A1 (https=)
EA (1) EA003530B1 (https=)
IL (1) IL129557A0 (https=)
IN (1) IN183409B (https=)
NZ (1) NZ335396A (https=)
PL (1) PL191249B1 (https=)
TW (1) TW509572B (https=)
UA (1) UA61090C2 (https=)
WO (1) WO1998020893A1 (https=)
ZA (1) ZA9710248B (https=)

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US6133456A (en) * 1994-08-18 2000-10-17 Ariad Gene Therapeutics, Inc. Synthetic multimerizing agents
US6150527A (en) * 1994-08-18 2000-11-21 Ariad Pharmaceuticals, Inc. Synthetic multimerizing agents
US20030036654A1 (en) * 1994-08-18 2003-02-20 Holt Dennis A. Synthetic multimerizing agents
US5859031A (en) 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
US6242468B1 (en) 1997-02-27 2001-06-05 Jia-He Li Carbamate and urea compositions and neurotrophic uses
ZA98825B (en) * 1997-02-27 1998-10-19 Guilford Pharm Inc Method of using neurotrophic carbamates and ureas
US6514686B2 (en) 1997-04-28 2003-02-04 The University Of British Columbia Method and composition for modulating amyloidosis
US20010049381A1 (en) 1997-06-04 2001-12-06 Gpl Nil Holdings, Inc., Pyrrolidine derivative hair growth compositions and uses
US5945441A (en) 1997-06-04 1999-08-31 Gpi Nil Holdings, Inc. Pyrrolidine carboxylate hair revitalizing agents
US6852496B1 (en) * 1997-08-12 2005-02-08 Oregon Health And Science University Methods of screening for agents that promote nerve cell growth
US5968921A (en) 1997-10-24 1999-10-19 Orgegon Health Sciences University Compositions and methods for promoting nerve regeneration
PL348671A1 (en) * 1998-06-03 2002-06-03 Gpi Nil Holdings Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres
US6331537B1 (en) 1998-06-03 2001-12-18 Gpi Nil Holdings, Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds
CN1295561A (zh) 1998-06-03 2001-05-16 Gpinil控股公司 N-杂环羧酸或羧酸等排物的n-结合氨磺酰
PT1098897E (pt) 1998-07-17 2004-10-29 Agouron Pharma Compostos composicoes e metodos para estimular o crescimento e a elongacao neuronal
GB9815880D0 (en) 1998-07-21 1998-09-16 Pfizer Ltd Heterocycles
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
US7338976B1 (en) * 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
US6395758B1 (en) 1998-08-14 2002-05-28 Gpi Nil Holdings, Inc. Small molecule carbamates or ureas for vision and memory disorders
US6462072B1 (en) 1998-09-21 2002-10-08 Gpi Nil Holdings, Inc. Cyclic ester or amide derivatives
US6228872B1 (en) * 1998-11-12 2001-05-08 Bristol-Myers Squibb Company Neurotrophic diamide and carbamate agents
WO2001002368A1 (en) * 1999-07-06 2001-01-11 Vertex Pharmaceuticals Incorporated N-heterocyclic derivatives with neuronal activity
US6809107B1 (en) * 1999-07-09 2004-10-26 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic pyrrolidines and piperidines, and related compositions and methods
US6734211B1 (en) 1999-07-09 2004-05-11 Oregon Health & Sciences University Compositions and methods for promoting nerve regeneration
WO2001017953A1 (en) 1999-09-08 2001-03-15 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
HK1046108B (en) * 1999-11-12 2007-01-05 Alcon, Inc. Neurophilin ligands for treating ocular conditions
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6818643B1 (en) 1999-12-08 2004-11-16 Bristol-Myers Squibb Company Neurotrophic bicyclic diamides
CA2393466C (en) 1999-12-21 2010-01-19 Gpi Nil Holdings, Inc. Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same
JP2004532187A (ja) 2001-01-25 2004-10-21 ギルフォード ファーマシュウティカルズ インコーポレイテッド 三置換カルボサイクリックサイクロフィリン結合化合物とその用途
WO2002096420A2 (en) * 2001-05-29 2002-12-05 Guilford Pharmaceuticals Inc. Method for treating nerve injury caused by surgery
US20040147433A1 (en) * 2001-06-14 2004-07-29 Marcus Keep Neuroimmunophilins for selective neuronal radioprotection
WO2003062773A1 (en) * 2002-01-24 2003-07-31 Pei Electronics, Inc. Compact integrated infrared scene projector
MXPA05003471A (es) * 2002-10-03 2005-07-01 Vertex Pharma Derivados de piperazina y piperadina para el tratamiento de enfermedades neurologicas.
US20060189551A1 (en) * 2004-10-04 2006-08-24 Duke University Combination therapies for fungal pathogens
AU2005319454B2 (en) * 2004-12-20 2012-08-09 Wyeth Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders
CA2590254A1 (en) * 2004-12-20 2006-06-29 Wyeth Rapamycin derivatives and the uses thereof in the treatment of neurological disorders
ES2528674T3 (es) * 2005-02-17 2015-02-11 Astellas Pharma Inc. Piperidina y carboxilatos de piperacina como inhibidores de FAAH
EP1988920A1 (en) * 2006-02-02 2008-11-12 Rinat Neuroscience Corp. Methods for treating obesity by administering a trkb antagonist
EP1988923A1 (en) * 2006-02-02 2008-11-12 Rinat Neuroscience Corp. Methods for treating unwanted weight loss or eating disorders by administering a trkb agonist
CN112218683A (zh) 2018-05-30 2021-01-12 睿谱外科系统股份有限公司 靠近关键结构的辐射外科手术神经调节
CN116763768B (zh) * 2022-03-15 2026-03-20 润佳(苏州)医药科技有限公司 同位素富集的3-氨基-1-丙磺酸衍生物及其用途

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US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
ES2137186T3 (es) * 1991-05-09 1999-12-16 Vertex Pharma Nuevos compuestos inmunosupresores.
NZ314207A (en) * 1992-09-28 2000-12-22 Vertex Pharma 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers
US5744485A (en) * 1994-03-25 1998-04-28 Vertex Pharmaceuticals Incorporated Carbamates and ureas as modifiers of multi-drug resistance
IL115685A (en) * 1994-11-16 2000-08-31 Vertex Pharma Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
US5543423A (en) * 1994-11-16 1996-08-06 Vertex Pharmaceuticals, Incorporated Amino acid derivatives with improved multi-drug resistance activity
US5726184A (en) * 1995-05-19 1998-03-10 Vertex Pharmaceuticals Incorporated Tetralin compounds with improved MDR activity
US5614547A (en) * 1995-06-07 1997-03-25 Guilford Pharmaceuticals Inc. Small molecule inhibitors of rotamase enzyme
US5696135A (en) * 1995-06-07 1997-12-09 Gpi Nil Holdings, Inc. Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth
US5859031A (en) * 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
US6037370A (en) * 1995-06-08 2000-03-14 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth
US5801197A (en) * 1995-10-31 1998-09-01 Gpi Nil Holdings, Inc. Rotamase enzyme activity inhibitors
US5811434A (en) * 1996-11-13 1998-09-22 Vertex Pharmacueticals Incorporated Methods and compositions for stimulating neurite growth
US5840736A (en) * 1996-11-13 1998-11-24 Vertex Pharmaceuticals Incorporated Methods and compositions for stimulating neurite growth
US9604852B2 (en) * 2012-09-28 2017-03-28 Dic Corporation α-alumina particles and method for manufacturing the same

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