JP2001503396A - 治療用リポソーム組成物および方法 - Google Patents
治療用リポソーム組成物および方法Info
- Publication number
- JP2001503396A JP2001503396A JP51862298A JP51862298A JP2001503396A JP 2001503396 A JP2001503396 A JP 2001503396A JP 51862298 A JP51862298 A JP 51862298A JP 51862298 A JP51862298 A JP 51862298A JP 2001503396 A JP2001503396 A JP 2001503396A
- Authority
- JP
- Japan
- Prior art keywords
- liposome
- affinity moiety
- hydrophilic polymer
- bond
- liposomes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2792396P | 1996-10-11 | 1996-10-11 | |
| US60/027,923 | 1996-10-11 | ||
| PCT/US1997/018813 WO1998016201A1 (en) | 1996-10-11 | 1997-10-09 | Therapeutic liposome composition and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001503396A true JP2001503396A (ja) | 2001-03-13 |
| JP2001503396A5 JP2001503396A5 (https=) | 2005-06-16 |
Family
ID=21840552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51862298A Ceased JP2001503396A (ja) | 1996-10-11 | 1997-10-09 | 治療用リポソーム組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US6043094A (https=) |
| EP (1) | EP0932390A1 (https=) |
| JP (1) | JP2001503396A (https=) |
| AU (1) | AU4907897A (https=) |
| WO (1) | WO1998016201A1 (https=) |
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| JP2002542341A (ja) * | 1999-04-20 | 2002-12-10 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | カチオン性ｐｅｇ脂質および使用方法。 |
| JP2005513104A (ja) * | 2001-12-06 | 2005-05-12 | イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム | テンパミン（ｔｅｍｐａｍｉｎｅ）組成物および使用方法 |
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| GB8430252D0 (en) * | 1984-11-30 | 1985-01-09 | Beecham Group Plc | Compounds |
| US4952394A (en) * | 1987-11-23 | 1990-08-28 | Bristol-Myers Company | Drug-monoclonal antibody conjugates |
| US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| JP3220180B2 (ja) * | 1991-05-23 | 2001-10-22 | 三菱化学株式会社 | 薬剤含有タンパク質結合リポソーム |
| WO1994021281A1 (en) * | 1993-03-23 | 1994-09-29 | Liposome Technology, Inc. | Polymer-polypeptide composition and method |
| JP2001503396A (ja) * | 1996-10-11 | 2001-03-13 | アルザ コーポレイション | 治療用リポソーム組成物および方法 |
-
1997
- 1997-10-09 JP JP51862298A patent/JP2001503396A/ja not_active Ceased
- 1997-10-09 WO PCT/US1997/018813 patent/WO1998016201A1/en not_active Ceased
- 1997-10-09 EP EP97911782A patent/EP0932390A1/en not_active Withdrawn
- 1997-10-09 AU AU49078/97A patent/AU4907897A/en not_active Abandoned
- 1997-10-10 US US08/949,039 patent/US6043094A/en not_active Expired - Lifetime
-
2000
- 2000-02-10 US US09/501,857 patent/US6660525B2/en not_active Expired - Lifetime
-
2003
- 2003-07-08 US US10/616,094 patent/US6958241B2/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002542341A (ja) * | 1999-04-20 | 2002-12-10 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | カチオン性ｐｅｇ脂質および使用方法。 |
| JP2005513104A (ja) * | 2001-12-06 | 2005-05-12 | イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム | テンパミン（ｔｅｍｐａｍｉｎｅ）組成物および使用方法 |
| JP2010150264A (ja) * | 2005-12-19 | 2010-07-08 | Ind Technol Res Inst | グルタチオンベースデリバリーシステム |
| US8673863B2 (en) | 2005-12-19 | 2014-03-18 | Industrial Technology Research Institute | Glutathione-based delivery system |
| JPWO2008026781A1 (ja) * | 2006-08-31 | 2010-01-21 | 直人 奥 | 逆標的化脂質小胞体 |
| JP2013515767A (ja) * | 2009-12-29 | 2013-05-09 | キョンブク ナショナル ユニバーシティ インダストリー−アカデミック コーオペレーション ファウンデーション | インターロイキン−４受容体を特異的に標的とするペプチドで標識されたリポソームを含有する癌診断又は治療用標的指向型薬物伝達システム、及びその製造方法 |
| JP2020026397A (ja) * | 2018-08-09 | 2020-02-20 | 国立大学法人 岡山大学 | ＴｒｋＢアンタゴニストを含む医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6660525B2 (en) | 2003-12-09 |
| US20020102733A1 (en) | 2002-08-01 |
| EP0932390A1 (en) | 1999-08-04 |
| US20040009217A1 (en) | 2004-01-15 |
| US6043094A (en) | 2000-03-28 |
| WO1998016201A1 (en) | 1998-04-23 |
| US6958241B2 (en) | 2005-10-25 |
| AU4907897A (en) | 1998-05-11 |
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