|
DE69534530T2
(de)
*
|
1994-08-12 |
2006-07-06 |
Immunomedics, Inc. |
Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
|
|
US8771694B2
(en)
*
|
1994-08-12 |
2014-07-08 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for B-cell lymphoma and leukemia cells
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
US6653104B2
(en)
*
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
DK0932417T3
(da)
*
|
1996-10-17 |
2003-04-14 |
Immunomedics Inc |
Non-antigent toxinkonjugat og fusionsprotein af internaliserende receptorsystem
|
|
JP3835827B2
(ja)
*
|
1997-05-02 |
2006-10-18 |
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ，アズ リプレゼンティッド バイ ザ セクレタリーオブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
悪性細胞に対する、ｏｎｃタンパク質を含む、免疫毒素
|
|
US6187284B1
(en)
*
|
1997-09-03 |
2001-02-13 |
Immunomedics, Inc. |
Fluorination of proteins and peptides for F-18 positron emission tomography
|
|
JP2002509158A
(ja)
*
|
1998-01-15 |
2002-03-26 |
センター・フォー・モレキュラー・メディシン・アンド・イムノロジー |
アーム付きリガンドの送達向上のための抗体と受容体ターゲティング部分
|
|
US6703488B1
(en)
|
1998-01-15 |
2004-03-09 |
Center For Molecular Medicine And Immunology |
Antibody/receptor targeting moiety for enhanced delivery of armed ligand
|
|
US6869604B1
(en)
*
|
1998-03-27 |
2005-03-22 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Recombinant anti-tumor RNAse
|
|
WO2000067796A1
(en)
|
1999-05-07 |
2000-11-16 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
US6949520B1
(en)
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
|
US7045283B2
(en)
*
|
2000-10-18 |
2006-05-16 |
The Regents Of The University Of California |
Methods of high-throughput screening for internalizing antibodies
|
|
US7329405B2
(en)
*
|
2001-08-23 |
2008-02-12 |
Genmab A/S |
Human antibodies specific for interleukin 15 (IL-15)
|
|
US7247304B2
(en)
*
|
2001-08-23 |
2007-07-24 |
Genmab A/S |
Methods of treating using anti-IL-15 antibodies
|
|
RS51829B
(sr)
*
|
2001-08-23 |
2012-02-29 |
Genmab A/S. |
Ljudska antitela specifična za interleukin 15 (il-15)
|
|
CA2513287A1
(en)
*
|
2002-01-14 |
2003-07-17 |
William Herman |
Multispecific binding molecules
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US8658773B2
(en)
|
2011-05-02 |
2014-02-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
|
GB0308731D0
(en)
*
|
2003-04-15 |
2003-05-21 |
Anticancer Therapeutic Inv Sa |
Method of radiotherapy
|
|
US20050261170A1
(en)
*
|
2004-01-22 |
2005-11-24 |
Immunomedics, Inc. |
Folate conjugates and complexes
|
|
JP2008505853A
(ja)
|
2004-04-13 |
2008-02-28 |
クインテセンス バイオサイエンシーズ インコーポレーティッド |
細胞傷害性薬剤としての非天然のリボヌクレアーゼ複合体
|
|
JP2008515896A
(ja)
*
|
2004-10-05 |
2008-05-15 |
オクスナー クリニック ファウンデーション |
Ｉｌ−１５によるｂ細胞増殖の増強
|
|
JP5225069B2
(ja)
|
2005-03-23 |
2013-07-03 |
ゲンマブ エー／エス |
多発性骨髄腫の治療のためのｃｄ３８に対する抗体
|
|
US7842279B2
(en)
|
2005-08-31 |
2010-11-30 |
Immunomedics, Inc. |
F-18 peptides for pre targeted positron emission tomography imaging
|
|
CA2646329C
(en)
|
2006-03-20 |
2018-07-03 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
|
US8840882B2
(en)
*
|
2006-06-23 |
2014-09-23 |
Quintessence Biosciences, Inc. |
Modified ribonucleases
|
|
WO2008010991A2
(en)
|
2006-07-17 |
2008-01-24 |
Quintessence Biosciences, Inc. |
Methods and compositions for the treatment of cancer
|
|
WO2008037257A2
(en)
|
2006-09-26 |
2008-04-03 |
Genmab A/S |
Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
|
|
JPWO2008133141A1
(ja)
*
|
2007-04-24 |
2010-07-22 |
東洋紡績株式会社 |
オスモチン組換えタンパク質およびその製造方法、並びにその利用
|
|
WO2009032949A2
(en)
|
2007-09-04 |
2009-03-12 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
|
|
WO2009048909A1
(en)
*
|
2007-10-08 |
2009-04-16 |
Quintessence Biosciences, Inc. |
Compositions and methods for ribonuclease-based therapies
|
|
EP3043181B1
(en)
|
2008-01-15 |
2020-04-08 |
The Board of Trustees of the Leland Stanford Junior University |
Markers of acute myeloid leukemia stem cells
|
|
US11072655B2
(en)
|
2008-01-15 |
2021-07-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Markers of acute myeloid leukemia stem cells
|
|
ES2582340T3
(es)
|
2008-01-15 |
2016-09-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Métodos para manipular fagocitosis mediada por CD47
|
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
|
BRPI0920743A2
(pt)
|
2008-10-01 |
2016-09-20 |
Quintessence Biosciences Inc |
ribonucleases terapeuticas
|
|
ES3000111T3
(en)
|
2009-02-13 |
2025-02-27 |
Immunomedics Inc |
Intermediates for preparing conjugates with an intracellularly-cleavable linkage
|
|
US20160095939A1
(en)
|
2014-10-07 |
2016-04-07 |
Immunomedics, Inc. |
Neoadjuvant use of antibody-drug conjugates
|
|
ES2712732T3
(es)
|
2009-02-17 |
2019-05-14 |
Cornell Res Foundation Inc |
Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
|
|
GB0905438D0
(en)
*
|
2009-03-30 |
2009-05-13 |
Ge Healthcare Ltd |
Radiolabelling reagents and methods
|
|
CN102395602B
(zh)
|
2009-04-16 |
2017-10-24 |
夏里特柏林大学医学院 |
在疾病治疗方法中使用的b‑淋巴细胞靶向剂
|
|
MX341084B
(es)
|
2009-11-02 |
2016-08-05 |
Univ Washington |
Composiciones de nucleasas terapéuticas y métodos.
|
|
AU2010325969B2
(en)
|
2009-12-02 |
2016-10-20 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
|
|
GB201002508D0
(en)
|
2010-02-12 |
2010-03-31 |
Algeta As |
Product
|
|
SMT202000031T1
(it)
|
2010-06-09 |
2020-03-13 |
Genmab As |
Anticorpi contro cd38 umano
|
|
ES2666303T3
(es)
|
2011-04-29 |
2018-05-03 |
University Of Washington |
Composiciones terapéuticas de nucleasa y métodos
|
|
EP2825553B1
(en)
|
2012-03-14 |
2018-07-25 |
Regeneron Pharmaceuticals, Inc. |
Multispecific antigen-binding molecules and uses thereof
|
|
CN104619350A
(zh)
|
2012-06-14 |
2015-05-13 |
Ambrx公司 |
结合到核受体配体多肽的抗psma抗体
|
|
WO2017004144A1
(en)
|
2015-07-01 |
2017-01-05 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
CN107753954A
(zh)
|
2012-12-13 |
2018-03-06 |
免疫医疗公司 |
功效改进且毒性降低的抗体与sn‑38的免疫缀合物的剂量
|
|
US11559580B1
(en)
|
2013-09-17 |
2023-01-24 |
Blaze Bioscience, Inc. |
Tissue-homing peptide conjugates and methods of use thereof
|
|
HRP20192080T1
(hr)
|
2013-10-31 |
2020-02-07 |
Resolve Therapeutics, Llc |
Terapeutske fuzije nukleaza-albumine i postupci
|
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
|
US9603927B2
(en)
|
2014-02-28 |
2017-03-28 |
Janssen Biotech, Inc. |
Combination therapies with anti-CD38 antibodies
|
|
PH12017500442B1
(en)
|
2014-09-09 |
2023-05-24 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
|
CN107406506A
(zh)
|
2014-12-04 |
2017-11-28 |
詹森生物科技公司 |
用于治疗急性髓系白血病的抗cd38抗体
|
|
AU2016252771B2
(en)
|
2015-04-22 |
2021-12-16 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
|
|
EA201792546A1
(ru)
|
2015-05-20 |
2018-04-30 |
Янссен Байотек, Инк. |
Антитела к cd38 для лечения амилоидоза легких цепей и прочих cd38-положительных гематологических злокачественных опухолей
|
|
IL256242B2
(en)
|
2015-06-22 |
2024-09-01 |
Janssen Biotech Inc |
Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors
|
|
US20170044265A1
(en)
|
2015-06-24 |
2017-02-16 |
Janssen Biotech, Inc. |
Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
|
|
JP6980980B2
(ja)
|
2015-06-25 |
2021-12-15 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
抗ｈｌａ‐ｄｒまたは抗ｔｒｏｐ‐２抗体と微小管阻害剤、ｐａｒｐ阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド３‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する
|
|
IL296285A
(en)
|
2015-07-06 |
2022-11-01 |
Regeneron Pharma |
Multispecific antigen-binding molecules and uses thereof
|
|
US11254744B2
(en)
|
2015-08-07 |
2022-02-22 |
Imaginab, Inc. |
Antigen binding constructs to target molecules
|
|
WO2017044894A2
(en)
|
2015-09-09 |
2017-03-16 |
Fred Hutchinson Cancer Research Center |
Cartilage-homing peptides
|
|
CA3004152C
(en)
|
2015-11-03 |
2024-04-16 |
Janssen Biotech, Inc. |
Subcutaneous formulations of anti-cd38 antibodies and their uses
|
|
US10781261B2
(en)
|
2015-11-03 |
2020-09-22 |
Janssen Biotech, Inc. |
Subcutaneous formulations of anti-CD38 antibodies and their uses
|
|
EP3448891A1
(en)
|
2016-04-28 |
2019-03-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of making multispecific antigen-binding molecules
|
|
US20190233533A1
(en)
|
2016-06-28 |
2019-08-01 |
Umc Utrecht Holding B.V. |
Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
|
|
CA3029627A1
(en)
|
2016-07-01 |
2018-01-04 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
|
WO2018136614A1
(en)
|
2017-01-18 |
2018-07-26 |
Fred Hutchinson Cancer Research Center |
Peptide compositions and methods of use thereof for disrupting tead interactions
|
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
|
EP3595699A4
(en)
|
2017-03-16 |
2020-12-23 |
Blaze Bioscience, Inc. |
PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE
|
|
EP3630046B1
(en)
|
2017-05-30 |
2024-12-25 |
The Board of Regents of the University of Oklahoma |
Anti-doublecortin-like kinase 1 antibodies and methods of use
|
|
DK3635009T3
(da)
|
2017-06-07 |
2026-03-30 |
Regeneron Pharma |
Sammensætninger og fremgangsmåder til internalisering af enzymer
|
|
EP3638290A4
(en)
|
2017-06-15 |
2021-04-07 |
Blaze Bioscience, Inc. |
KIDNEY HOMING PEPTIDE CONJUGATES AND METHOD OF USING THEREOF
|
|
CA3073537A1
(en)
|
2017-08-22 |
2019-02-28 |
Sanabio, Llc |
Soluble interferon receptors and uses thereof
|
|
MA50514A
(fr)
|
2017-10-31 |
2020-09-09 |
Janssen Biotech Inc |
Méthodes de traitement du myélome multiple à haut risque
|
|
CA3086040A1
(en)
*
|
2017-12-19 |
2019-06-27 |
Blaze Bioscience, Inc. |
Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof
|
|
US12258597B2
(en)
|
2018-02-07 |
2025-03-25 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for therapeutic protein delivery
|
|
BR112020023145A2
(pt)
|
2018-05-17 |
2021-02-02 |
Regeneron Pharmaceuticals, Inc. |
anticorpo anti-cd63 ou fragmento de ligação ao antígeno do mesmo, molécula de ligação ao antígeno biespecífica, proteína terapêutica de múltiplos domínios, polinucleotídeo composição farmacêutica, e, composto
|
|
WO2021050789A1
(en)
|
2019-09-10 |
2021-03-18 |
Obsidian Therapeutics, Inc. |
Ca2-il15 fusion proteins for tunable regulation
|
|
US12043671B2
(en)
|
2021-06-16 |
2024-07-23 |
Gundersen Lutheran Medical Foundation, Inc. |
Antibodies targeting an amphiregulin-derived cell surface neo-epitope
|