|
EP1146907A2
(en)
*
|
1999-02-05 |
2001-10-24 |
Genzyme Corporation |
Use of cationic lipids to generate anti-tumor immunity
|
|
EP1210046A4
(en)
*
|
1999-06-22 |
2007-05-02 |
Res Dev Foundation |
IMPROVED DRESSING THAT CAN ACCELERATE THE HEALING OF INJURIES
|
|
WO2001024773A1
(en)
*
|
1999-10-01 |
2001-04-12 |
Lipoxen Technologies Limited |
Liposome-entrapped dna oral vaccines
|
|
US7381421B2
(en)
|
1999-12-13 |
2008-06-03 |
Lipoxen Technologies Limited |
Liposomes
|
|
US6372250B1
(en)
*
|
2000-04-25 |
2002-04-16 |
The Regents Of The University Of California |
Non-invasive gene targeting to the brain
|
|
DE10109897A1
(de)
*
|
2001-02-21 |
2002-11-07 |
Novosom Ag |
Fakultativ kationische Liposomen und Verwendung dieser
|
|
US7604803B2
(en)
|
2002-07-05 |
2009-10-20 |
Lipoxen Technologies Limited |
Method to enhance an immune response of nucleic acid vaccination
|
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
|
JP4546115B2
(ja)
*
|
2004-03-05 |
2010-09-15 |
三菱化学メディエンス株式会社 |
細胞中ａｔｐの定量法
|
|
DE102004057303A1
(de)
*
|
2004-11-26 |
2006-06-01 |
Merck Patent Gmbh |
Stabile Kristallmodifikationen von DOTAP Chlorid
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
CN100400667C
(zh)
*
|
2006-06-27 |
2008-07-09 |
浙江大学 |
脂质体包裹弓形虫pGRA4真核表达质粒的方法及用途
|
|
CA2687208C
(en)
|
2006-12-22 |
2017-02-14 |
Soluciones Biotecnologicas Innovacion Ltda |
Process and formulation for immunizing fish in aquaculture systems
|
|
RU2367443C1
(ru)
*
|
2008-02-28 |
2009-09-20 |
Общество с ограниченной ответственностью "Битеп" |
Средство на основе природных фосфолипидов
|
|
EP2184054A1
(en)
|
2008-11-08 |
2010-05-12 |
Lipoxen Technologies Limited |
Small Interfering RNA Delivery
|
|
JP5854559B2
(ja)
*
|
2009-07-06 |
2016-02-09 |
ヴァリエーション バイオテクノロジーズ インコーポレイテッド |
小胞を調製する方法及びこれから製造される製剤
|
|
CA2803282C
(en)
|
2009-07-06 |
2018-05-01 |
David E. Anderson |
Methods for preparing vesicles and formulations produced therefrom
|
|
US12419839B2
(en)
|
2009-10-09 |
2025-09-23 |
Signablok, Inc. |
Methods and compositions for targeted delivery of protein fragments
|
|
US10525152B2
(en)
|
2009-10-09 |
2020-01-07 |
Signablok, Inc. |
Methods and compositions for targeted imaging
|
|
US10894098B2
(en)
|
2012-04-09 |
2021-01-19 |
Signablok, Inc. |
Methods and compositions for targeted imaging
|
|
EP3318248B1
(en)
|
2009-12-01 |
2019-04-10 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
KR101773643B1
(ko)
*
|
2010-04-28 |
2017-08-31 |
교와 핫꼬 기린 가부시키가이샤 |
양이온성 지질
|
|
NZ606591A
(en)
|
2010-07-06 |
2015-02-27 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
MX342608B
(es)
|
2010-07-06 |
2016-10-06 |
Novartis Ag * |
Particulas de suministro similares a viriones para moleculas de arn de autorreplicacion.
|
|
ES2557382T3
(es)
|
2010-07-06 |
2016-01-25 |
Glaxosmithkline Biologicals Sa |
Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN
|
|
EP2591114B1
(en)
|
2010-07-06 |
2016-06-08 |
GlaxoSmithKline Biologicals SA |
Immunisation of large mammals with low doses of rna
|
|
WO2012006367A2
(en)
|
2010-07-06 |
2012-01-12 |
Variation Biotechnologies, Inc. |
Compositions and methods for treating influenza
|
|
ES2646669T3
(es)
|
2010-07-06 |
2017-12-14 |
Glaxosmithkline Biologicals Sa |
Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
|
|
LT4226941T
(lt)
|
2010-08-31 |
2025-01-10 |
Glaxosmithkline Biologicals Sa |
Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui
|
|
WO2012051211A2
(en)
|
2010-10-11 |
2012-04-19 |
Novartis Ag |
Antigen delivery platforms
|
|
US10736844B2
(en)
|
2011-01-13 |
2020-08-11 |
Variation Biotechnologies Inc. |
Compositions and methods for treating viral infections
|
|
RU2491062C2
(ru)
*
|
2011-03-16 |
2013-08-27 |
Общество С Ограниченной Ответственностью "Биотехнологии Пущино" |
Композиции протекторов острых и хронических печеночных энцелопатий и способ лечения острых и хронических печеночных энцелопатий
|
|
PL3892295T3
(pl)
|
2011-05-24 |
2023-07-24 |
BioNTech SE |
Zindywidualizowane szczepionki przeciwnowotworowe
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
EP2729165B1
(en)
|
2011-07-06 |
2017-11-08 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
|
JP6059220B2
(ja)
|
2011-07-06 |
2017-01-18 |
ノバルティス アーゲー |
核酸を含む水中油型エマルジョン
|
|
MX350258B
(es)
|
2011-07-06 |
2017-08-31 |
Novartis Ag |
Emulsiones cationicas de aceite en agua.
|
|
AU2013208693B2
(en)
|
2012-01-12 |
2017-12-07 |
Variation Biotechnologies Inc. |
Compositions and methods for treating viral infections
|
|
EP2806894A4
(en)
|
2012-01-27 |
2015-11-04 |
Variation Biotechnologies Inc |
METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENTS
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
WO2013185067A1
(en)
|
2012-06-08 |
2013-12-12 |
Shire Human Genetic Therapies, Inc. |
Nuclease resistant polynucleotides and uses thereof
|
|
EP2858679B2
(en)
*
|
2012-06-08 |
2024-06-05 |
Translate Bio, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
|
EP3417874B1
(en)
|
2012-11-28 |
2024-09-11 |
BioNTech SE |
Individualized vaccines for cancer
|
|
JP6586075B2
(ja)
|
2013-03-14 |
2019-10-02 |
トランスレイト バイオ， インコーポレイテッド |
メッセンジャーｒｎａの精製方法
|
|
RS57739B1
(sr)
|
2013-03-14 |
2018-12-31 |
Translate Bio Inc |
Kompozicije cftr irnk i postupci i upotrebe u vezi sa njima
|
|
WO2014180490A1
(en)
|
2013-05-10 |
2014-11-13 |
Biontech Ag |
Predicting immunogenicity of t cell epitopes
|
|
JP6506749B2
(ja)
|
2013-10-22 |
2019-04-24 |
シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド |
フェニルケトン尿症のためのｍＲＮＡ療法
|
|
CN106413811A
(zh)
|
2013-10-22 |
2017-02-15 |
夏尔人类遗传性治疗公司 |
精氨基琥珀酸合成酶缺乏症的mrna疗法
|
|
US20160324986A1
(en)
*
|
2013-12-27 |
2016-11-10 |
Teloregen, Inc. |
Compositions and methods for providing active telomerase to cells in vivo
|
|
BR112016016356B1
(pt)
*
|
2014-01-17 |
2023-12-26 |
Fundació Institut Català De Nanociència I Nanotecnologia |
Lipossoma, usos dos mesmos, e composição farmacêutica ou veterinária
|
|
US9850269B2
(en)
|
2014-04-25 |
2017-12-26 |
Translate Bio, Inc. |
Methods for purification of messenger RNA
|
|
WO2016045732A1
(en)
|
2014-09-25 |
2016-03-31 |
Biontech Rna Pharmaceuticals Gmbh |
Stable formulations of lipids and liposomes
|
|
WO2016128060A1
(en)
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
WO2017059902A1
(en)
|
2015-10-07 |
2017-04-13 |
Biontech Rna Pharmaceuticals Gmbh |
3' utr sequences for stabilization of rna
|
|
EA201991747A1
(ru)
|
2017-02-27 |
2020-06-04 |
Транслейт Био, Инк. |
НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR
|
|
MX2019013752A
(es)
|
2017-05-16 |
2020-07-20 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
|
|
WO2018224166A1
(en)
|
2017-06-09 |
2018-12-13 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
|
|
KR102950141B1
(ko)
|
2018-08-24 |
2026-04-07 |
트랜슬레이트 바이오 인코포레이티드 |
전령 rna의 정제 방법
|
|
WO2020106946A1
(en)
|
2018-11-21 |
2020-05-28 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
EP4031662A1
(en)
|
2019-09-20 |
2022-07-27 |
Translate Bio, Inc. |
Mrna encoding engineered cftr
|
|
EP3892260A1
(en)
*
|
2020-04-10 |
2021-10-13 |
Bayer Animal Health GmbH |
Immunostimulatory compositions based on liposomes with zwiterionic and cationic lipids
|
|
WO2022204032A1
(en)
|
2021-03-22 |
2022-09-29 |
Illumina Cambridge Limited |
Methods for improving nucleic acid cluster clonality
|