JP2001258868A5 - - Google Patents
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- JP2001258868A5 JP2001258868A5 JP2000120189A JP2000120189A JP2001258868A5 JP 2001258868 A5 JP2001258868 A5 JP 2001258868A5 JP 2000120189 A JP2000120189 A JP 2000120189A JP 2000120189 A JP2000120189 A JP 2000120189A JP 2001258868 A5 JP2001258868 A5 JP 2001258868A5
- Authority
- JP
- Japan
- Prior art keywords
- blood
- microcapillary
- flow path
- serum
- analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000008280 blood Substances 0.000 description 87
- 210000004369 blood Anatomy 0.000 description 86
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 41
- 239000010453 quartz Substances 0.000 description 40
- 210000002966 serum Anatomy 0.000 description 38
- 238000001914 filtration Methods 0.000 description 36
- 239000000758 substrate Substances 0.000 description 32
- 238000004458 analytical method Methods 0.000 description 31
- 210000002381 plasma Anatomy 0.000 description 26
- 238000000926 separation method Methods 0.000 description 26
- 238000004159 blood analysis Methods 0.000 description 25
- 238000000034 method Methods 0.000 description 24
- 229920000642 polymer Polymers 0.000 description 19
- 238000005370 electroosmosis Methods 0.000 description 17
- 238000005259 measurement Methods 0.000 description 17
- 239000000126 substance Substances 0.000 description 17
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 15
- 239000008103 glucose Substances 0.000 description 15
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 12
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 10
- 239000011248 coating agent Substances 0.000 description 10
- 238000000576 coating method Methods 0.000 description 10
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 10
- 239000011162 core material Substances 0.000 description 9
- 230000036541 health Effects 0.000 description 9
- 239000008055 phosphate buffer solution Substances 0.000 description 9
- 238000011144 upstream manufacturing Methods 0.000 description 8
- 230000009471 action Effects 0.000 description 7
- 239000011651 chromium Substances 0.000 description 7
- 239000011521 glass Substances 0.000 description 7
- 150000002500 ions Chemical class 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 6
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 6
- 238000009534 blood test Methods 0.000 description 6
- 239000011575 calcium Substances 0.000 description 6
- 229910052791 calcium Inorganic materials 0.000 description 6
- 230000005684 electric field Effects 0.000 description 6
- 239000004310 lactic acid Substances 0.000 description 6
- 235000014655 lactic acid Nutrition 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- 239000011591 potassium Substances 0.000 description 6
- 229910052700 potassium Inorganic materials 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 229910052708 sodium Inorganic materials 0.000 description 6
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 5
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 5
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 5
- 239000003114 blood coagulation factor Substances 0.000 description 5
- 239000012888 bovine serum Substances 0.000 description 5
- 239000001569 carbon dioxide Substances 0.000 description 5
- 229910002092 carbon dioxide Inorganic materials 0.000 description 5
- 150000001768 cations Chemical class 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000007789 gas Substances 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000011574 phosphorus Substances 0.000 description 5
- 229910052698 phosphorus Inorganic materials 0.000 description 5
- 229910001220 stainless steel Inorganic materials 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- 238000003860 storage Methods 0.000 description 5
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 4
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 229920001971 elastomer Polymers 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 238000005530 etching Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 229910052697 platinum Inorganic materials 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 229910001415 sodium ion Inorganic materials 0.000 description 4
- WOQDKFVDSKUVFC-UHFFFAOYSA-O CC(=C)C(=O)CCP(=O)=C(O)C[N+](C)(C)C Chemical compound CC(=C)C(=O)CCP(=O)=C(O)C[N+](C)(C)C WOQDKFVDSKUVFC-UHFFFAOYSA-O 0.000 description 3
- 150000001450 anions Chemical class 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 239000012503 blood component Substances 0.000 description 3
- 210000001772 blood platelet Anatomy 0.000 description 3
- 239000007853 buffer solution Substances 0.000 description 3
- UBAZGMLMVVQSCD-UHFFFAOYSA-N carbon dioxide;molecular oxygen Chemical compound O=O.O=C=O UBAZGMLMVVQSCD-UHFFFAOYSA-N 0.000 description 3
- 230000015271 coagulation Effects 0.000 description 3
- 238000005345 coagulation Methods 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000001962 electrophoresis Methods 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 238000009616 inductively coupled plasma Methods 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 210000000265 leukocyte Anatomy 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000007935 neutral effect Effects 0.000 description 3
- 230000003405 preventing effect Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- OXJGJKIURHREKH-UHFFFAOYSA-O CC(=C)C(=O)OCCP(=O)=C(O)C[N+](C)(C)C Chemical compound CC(=C)C(=O)OCCP(=O)=C(O)C[N+](C)(C)C OXJGJKIURHREKH-UHFFFAOYSA-O 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 229940019700 blood coagulation factors Drugs 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 238000005251 capillar electrophoresis Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000003792 electrolyte Substances 0.000 description 2
- 239000008151 electrolyte solution Substances 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 238000000691 measurement method Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 description 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 description 2
- 229920002120 photoresistant polymer Polymers 0.000 description 2
- 229910001414 potassium ion Inorganic materials 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- MBVFRSJFKMJRHA-UHFFFAOYSA-N 4-fluoro-1-benzofuran-7-carbaldehyde Chemical compound FC1=CC=C(C=O)C2=C1C=CO2 MBVFRSJFKMJRHA-UHFFFAOYSA-N 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 229910019213 POCl3 Inorganic materials 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229910052581 Si3N4 Inorganic materials 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- FNEPSTUXZLEUCK-UHFFFAOYSA-N benzo-15-crown-5 Chemical compound O1CCOCCOCCOCCOC2=CC=CC=C21 FNEPSTUXZLEUCK-UHFFFAOYSA-N 0.000 description 1
- FJSZDECKJYYBGE-UHFFFAOYSA-N bis(1,4,7,10-tetraoxacyclododec-2-ylmethyl) 2-dodecyl-2-methylpropanedioate Chemical compound C1OCCOCCOCCOC1COC(=O)C(C)(CCCCCCCCCCCC)C(=O)OCC1COCCOCCOCCO1 FJSZDECKJYYBGE-UHFFFAOYSA-N 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000000598 endocrine disruptor Substances 0.000 description 1
- 231100000049 endocrine disruptor Toxicity 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- KTWOOEGAPBSYNW-UHFFFAOYSA-N ferrocene Chemical compound [Fe+2].C=1C=C[CH-]C=1.C=1C=C[CH-]C=1 KTWOOEGAPBSYNW-UHFFFAOYSA-N 0.000 description 1
- 230000005669 field effect Effects 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000001139 pH measurement Methods 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 210000004180 plasmocyte Anatomy 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920006254 polymer film Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
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- 238000012797 qualification Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000007740 vapor deposition Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000120189A JP3847053B2 (ja) | 2000-03-15 | 2000-03-15 | 血液分析装置 |
| PCT/JP2001/001896 WO2001069242A1 (en) | 2000-03-15 | 2001-03-12 | Blood analyzing method and apparatus |
| US10/221,505 US20030114785A1 (en) | 2000-03-15 | 2001-03-12 | Blood analyzing method and apparatus |
| EP01912255A EP1267166A4 (en) | 2000-03-15 | 2001-03-12 | BLOOD ANALYSIS PROCESS AND DEVICE |
| KR1020027012030A KR20030004356A (ko) | 2000-03-15 | 2001-03-12 | 혈액 분석방법 및 장치 |
| AU2001241091A AU2001241091A1 (en) | 2000-03-15 | 2001-03-12 | Blood analyzing method and apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000120189A JP3847053B2 (ja) | 2000-03-15 | 2000-03-15 | 血液分析装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001258868A JP2001258868A (ja) | 2001-09-25 |
| JP2001258868A5 true JP2001258868A5 (enExample) | 2004-12-02 |
| JP3847053B2 JP3847053B2 (ja) | 2006-11-15 |
Family
ID=18631049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000120189A Expired - Fee Related JP3847053B2 (ja) | 2000-03-15 | 2000-03-15 | 血液分析装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20030114785A1 (enExample) |
| EP (1) | EP1267166A4 (enExample) |
| JP (1) | JP3847053B2 (enExample) |
| KR (1) | KR20030004356A (enExample) |
| AU (1) | AU2001241091A1 (enExample) |
| WO (1) | WO2001069242A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003084393A1 (en) | 2002-04-09 | 2003-10-16 | Matsushita Electric Industrial Co., Ltd. | Health management system and health management method |
| JP3803078B2 (ja) * | 2002-09-20 | 2006-08-02 | 独立行政法人科学技術振興機構 | 血液分析装置及び血漿分離方法 |
| JP2004354364A (ja) * | 2002-12-02 | 2004-12-16 | Nec Corp | 微粒子操作ユニット、それを搭載したチップと検出装置、ならびにタンパク質の分離、捕獲、および検出方法 |
| EP1600778B1 (en) | 2003-02-19 | 2013-07-24 | Japan Science and Technology Agency | Blood analysis device and blood analysis method |
| JP2004325185A (ja) * | 2003-04-23 | 2004-11-18 | Arkray Inc | 二段式検体分析用具 |
| US20040265172A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method and apparatus for entry and storage of specimens into a microfluidic device |
| WO2005024436A1 (ja) * | 2003-09-02 | 2005-03-17 | Nec Corporation | カスタマイズ可能なチップおよびその製造方法 |
| US7384791B2 (en) * | 2004-01-21 | 2008-06-10 | Hewlett-Packard Development Company, L.P. | Method of analyzing blood |
| WO2005088300A1 (en) * | 2004-03-16 | 2005-09-22 | Fuji Photo Film Co., Ltd. | Assay chip |
| KR20060130657A (ko) * | 2004-03-18 | 2006-12-19 | 후지 샤신 필름 가부시기가이샤 | 검체 검사방법에 사용되는 분석요소 |
| JP4478776B2 (ja) | 2004-08-09 | 2010-06-09 | 独立行政法人物質・材料研究機構 | 血液分析装置及び血液分析方法 |
| JP2006058093A (ja) * | 2004-08-18 | 2006-03-02 | National Institute For Materials Science | 血液分析装置 |
| US8140140B2 (en) * | 2005-02-14 | 2012-03-20 | Optiscan Biomedical Corporation | Analyte detection system for multiple analytes |
| EP2597471A3 (en) * | 2005-04-01 | 2014-03-05 | Konica Minolta Medical & Graphic, Inc. | Micro integrated analysis system, testing chip, and testing method |
| JP2007298502A (ja) * | 2006-04-04 | 2007-11-15 | Fujifilm Corp | 血球分離用フィルター |
| JP4893195B2 (ja) * | 2006-09-27 | 2012-03-07 | カシオ計算機株式会社 | 送液装置の接続構造体、燃料電池型発電装置及び電子機器 |
| EA201201363A1 (ru) * | 2006-11-21 | 2013-08-30 | Медимейт Холдинг Б.В. | Датчик ионов для текучей среды и способ его изготовления |
| EP1932924A1 (en) | 2006-11-22 | 2008-06-18 | FUJIFILM Corporation | Nucleic acid amplification method using microchip and microchip, and nucleic acid amplification system using the same |
| KR101346468B1 (ko) | 2007-05-18 | 2014-01-02 | 메디메이트 홀딩 비.브이. | 액체 중의 분석물질의 농도를 측정하기 위한 플러그를 갖는 시험 칩, 시험 칩용 하우징 및 플러그용 소켓 |
| CN104062454B (zh) | 2007-10-30 | 2016-01-20 | 松下健康医疗控股株式会社 | 分析用仪器 |
| JP2010025880A (ja) * | 2008-07-24 | 2010-02-04 | Takashi Omori | 生体細胞の機能の評価方法 |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| KR101057148B1 (ko) * | 2009-09-25 | 2011-08-17 | 주식회사 아이센스 | 휴대용 혈액 분석 장치 |
| JP5728778B2 (ja) * | 2010-06-01 | 2015-06-03 | 国立大学法人九州工業大学 | 解析装置及び解析装置の製造方法 |
| KR101379824B1 (ko) * | 2012-01-13 | 2014-04-01 | (주)유 바이오메드 | 실시간 분석물질 분리 및 동시진단할 수 있는 마이크로필터 칩 |
| WO2015157447A1 (en) * | 2014-04-08 | 2015-10-15 | Diagnostic Biochips | Device for biosensing with indwelling venous catheter |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
| EP4406654A3 (en) | 2015-01-12 | 2024-10-23 | Instrumentation Laboratory Company | Spatial separation of particles in a particle containing solution for biomedical sensing and detection |
| WO2017096284A1 (en) * | 2015-12-03 | 2017-06-08 | Ca Casyso Ag | Blood testing system and method |
| EP3459460A4 (en) | 2016-05-18 | 2020-01-29 | Terumo Kabushiki Kaisha | BLOOD INSPECTION SYSTEM AND BLOOD INSPECTION SYSTEM CONTROL METHOD |
| DE102018214459B3 (de) * | 2018-08-27 | 2019-12-24 | Robert Bosch Gmbh | Handgehaltenes Messgerät zur Analyse von Körperflüssigkeiten |
| DK3861318T3 (da) | 2018-10-02 | 2023-05-15 | Instr Laboratory Co | Engangshæmolysesensor |
| AU2021291903A1 (en) * | 2020-06-19 | 2023-03-02 | Sicong TAN | Integrated device, system and method for blood collection and analysis as well as intelligent image identification and diagnosis |
| WO2024014634A1 (ko) * | 2022-07-13 | 2024-01-18 | 주식회사 뮨 | 혈액 진단기능을 갖는 폐쇄채혈 자동화 장치 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3880592A (en) * | 1973-07-05 | 1975-04-29 | Instrumentation Labor Inc | Blood analysis system including a plasma separator |
| US4740472A (en) * | 1985-08-05 | 1988-04-26 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for automated processing and aliquoting of whole blood samples for analysis in a centrifugal fast analyzer |
| US5110724A (en) * | 1990-04-02 | 1992-05-05 | Cholestech Corporation | Multi-analyte assay device |
| US5242606A (en) * | 1990-06-04 | 1993-09-07 | Abaxis, Incorporated | Sample metering port for analytical rotor having overflow chamber |
| US5211310A (en) * | 1991-04-30 | 1993-05-18 | Andronic Devices Ltd. | Apparatus and method for dispensing phases of blood |
| US5730883A (en) * | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
| JPH05220218A (ja) * | 1992-02-13 | 1993-08-31 | Norio Nakabayashi | 抗血栓性再生セルロース系膜及びその製造方法 |
| US5591643A (en) * | 1993-09-01 | 1997-01-07 | Abaxis, Inc. | Simplified inlet channels |
| JP3443891B2 (ja) * | 1993-09-14 | 2003-09-08 | 日本油脂株式会社 | タンパク質吸着防止剤 |
| US5580523A (en) * | 1994-04-01 | 1996-12-03 | Bard; Allen J. | Integrated chemical synthesizers |
| US5651766A (en) * | 1995-06-07 | 1997-07-29 | Transfusion Technologies Corporation | Blood collection and separation system |
| US5589399A (en) * | 1994-10-21 | 1996-12-31 | First Medical, Inc. | System and method for plasma separation and measurement |
| JP3477918B2 (ja) * | 1995-05-29 | 2003-12-10 | 株式会社島津製作所 | キャピラリ電気泳動チップ |
| JP3166144B2 (ja) * | 1995-06-28 | 2001-05-14 | 横河電機株式会社 | マイクロ・ラボラトリー・システム |
| JP3884510B2 (ja) * | 1996-10-14 | 2007-02-21 | 日本油脂株式会社 | 固定化免疫学的活性物質の保存時安定化方法 |
| EP0913416B1 (en) * | 1997-04-17 | 2005-10-19 | Toyobo Co., Ltd. | Biocompatible polymers |
| JP3654481B2 (ja) * | 1997-06-05 | 2005-06-02 | 独立行政法人理化学研究所 | 生化学反応用マイクロリアクタ |
| CA2254223A1 (en) * | 1998-11-16 | 2000-05-16 | Biophys, Inc. | Device and method for analyzing a biologic sample |
| US6444106B1 (en) * | 1999-07-09 | 2002-09-03 | Orchid Biosciences, Inc. | Method of moving fluid in a microfluidic device |
-
2000
- 2000-03-15 JP JP2000120189A patent/JP3847053B2/ja not_active Expired - Fee Related
-
2001
- 2001-03-12 WO PCT/JP2001/001896 patent/WO2001069242A1/ja not_active Ceased
- 2001-03-12 KR KR1020027012030A patent/KR20030004356A/ko not_active Ceased
- 2001-03-12 US US10/221,505 patent/US20030114785A1/en not_active Abandoned
- 2001-03-12 AU AU2001241091A patent/AU2001241091A1/en not_active Abandoned
- 2001-03-12 EP EP01912255A patent/EP1267166A4/en not_active Withdrawn
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