JP2000508899A - キメライソプレノイド合成酵素およびその使用 - Google Patents

キメライソプレノイド合成酵素およびその使用

Info

Publication number
JP2000508899A
JP2000508899A JP9537218A JP53721897A JP2000508899A JP 2000508899 A JP2000508899 A JP 2000508899A JP 9537218 A JP9537218 A JP 9537218A JP 53721897 A JP53721897 A JP 53721897A JP 2000508899 A JP2000508899 A JP 2000508899A
Authority
JP
Japan
Prior art keywords
synthase
chimeric
isoprenoid
domain
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP9537218A
Other languages
English (en)
Japanese (ja)
Inventor
ジョゼフ チャペル
キョンハム バック
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kentucky
Original Assignee
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Kentucky filed Critical University of Kentucky
Publication of JP2000508899A publication Critical patent/JP2000508899A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP9537218A 1996-04-12 1997-04-11 キメライソプレノイド合成酵素およびその使用 Withdrawn JP2000508899A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/631,341 1996-04-12
US08/631,341 US5824774A (en) 1996-04-12 1996-04-12 Chimeric isoprenoid synthases and uses thereof
PCT/US1997/005986 WO1997038703A1 (en) 1996-04-12 1997-04-11 Chimeric isoprenoid synthases and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011186897A Division JP2012005499A (ja) 1996-04-12 2011-08-30 キメライソプレノイド合成酵素およびその使用

Publications (1)

Publication Number Publication Date
JP2000508899A true JP2000508899A (ja) 2000-07-18

Family

ID=24530791

Family Applications (4)

Application Number Title Priority Date Filing Date
JP9537218A Withdrawn JP2000508899A (ja) 1996-04-12 1997-04-11 キメライソプレノイド合成酵素およびその使用
JP2011186897A Pending JP2012005499A (ja) 1996-04-12 2011-08-30 キメライソプレノイド合成酵素およびその使用
JP2014259849A Pending JP2015057074A (ja) 1996-04-12 2014-12-24 キメライソプレノイド合成酵素およびその使用
JP2015134197A Pending JP2015171387A (ja) 1996-04-12 2015-07-03 キメライソプレノイド合成酵素およびその使用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2011186897A Pending JP2012005499A (ja) 1996-04-12 2011-08-30 キメライソプレノイド合成酵素およびその使用
JP2014259849A Pending JP2015057074A (ja) 1996-04-12 2014-12-24 キメライソプレノイド合成酵素およびその使用
JP2015134197A Pending JP2015171387A (ja) 1996-04-12 2015-07-03 キメライソプレノイド合成酵素およびその使用

Country Status (25)

Country Link
US (2) US5824774A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0904095B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (4) JP2000508899A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR20000005385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AP (1) AP808A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR006638A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE223225T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2726497A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9708650A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2250712C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ294613B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE69715192T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EA (1) EA001622B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2132046T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR990300025T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ID (1) ID19769A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (2) IL126486A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN186316B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA10895A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL329404A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT904095E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR199802043T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW509724B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1997038703A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA973108B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013162776A (ja) * 2012-02-13 2013-08-22 Sumitomo Rubber Ind Ltd イソプレノイドの製造方法、及びイソプレノイド

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186891B1 (en) * 1996-04-12 2007-03-06 University Of Kentucky, Research Foundation Plant cells and plants expressing chimeric isoprenoid synthases
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US8106260B2 (en) * 1996-04-12 2012-01-31 The Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof
US5945726A (en) * 1996-12-16 1999-08-31 Micron Technology, Inc. Lateral bipolar transistor
AR022383A1 (es) 1998-09-18 2002-09-04 Univ Kentucky Res Found Sintasas
ATE439437T1 (de) * 1999-01-05 2009-08-15 Univ Boston Verbessertes klonierungsverfahren
US6358712B1 (en) 1999-01-05 2002-03-19 Trustee Of Boston University Ordered gene assembly
US20040005673A1 (en) * 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
WO2002010398A2 (en) 2000-07-31 2002-02-07 Hahn Frederick M Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
AU2013204829B2 (en) * 2001-03-09 2013-07-04 University Of Kentucky Research Foundation Cytochrome P450s and uses thereof
US7405057B2 (en) * 2001-03-09 2008-07-29 Board Of Trustees Of The University Of Kentucky Cytochrome P450s and uses thereof
AU2012202780B2 (en) * 2001-03-09 2014-07-03 University Of Kentucky Research Foundation Cytochrome P450s and Uses Thereof
US7192751B2 (en) * 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7172886B2 (en) * 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7442785B2 (en) 2003-07-24 2008-10-28 The University Of Kentucky Research Foundation Sesquiterpene synthase gene and protein
US8124811B2 (en) * 2007-03-20 2012-02-28 Allylix, Inc. Fragrance and methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one
US8143039B2 (en) 2007-06-01 2012-03-27 Sapphire Energy, Inc. Use of genetically modified organisms to generate biomass degrading enzymes
JP2010539294A (ja) 2007-09-11 2010-12-16 サファイア エナジー,インコーポレイティド 光合成生物を用いた有機製品の製造方法ならびにその製品および組成物
CL2008002690A1 (es) * 2007-09-11 2009-07-17 Sapphire Energy Inc Vector aislado que comprende un acido nucleico que codifica una enzima que produce un isoprenoide con dos fosfatos y un promotor que permite la expresion en un cloroplasto; celula huesped que lo contiene y metodo para producir un isoprenoide.
MX2010006576A (es) * 2007-12-13 2010-10-15 Danisco Us Inc Composiciones y metodos para producir isopreno.
US8034992B2 (en) * 2008-06-16 2011-10-11 Academia Sinica Gibberellin 2-oxidase genes and uses thereof
WO2010019696A2 (en) 2008-08-12 2010-02-18 Allylix, Inc. Method for production of isoprenoids
US9303252B2 (en) 2010-10-29 2016-04-05 Evolva, Inc. Modified valencene synthase polypeptides, encoding nucleic acid molecules and uses thereof
WO2013110191A1 (en) 2012-01-23 2013-08-01 The University Of British Columbia Abc trepenoid transporters and methods of using the same
EP3929289A1 (en) 2012-07-30 2021-12-29 Evolva, Inc. Sclareol and labdenediol diphosphate synthase polypeptides, encoding nucleic acid molecules and uses thereof
AU2013337574B2 (en) 2012-11-01 2018-07-05 The University Of British Columbia Cytochrome P450 and cytochrome P450 reductase polypeptides, encoding nucleic acid molecules and uses thereof
HUE035866T2 (en) 2013-03-14 2018-05-28 Evolva Inc Valencene synthase polypeptides, coding nucleic acid molecules and their use
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6449794A (en) * 1993-04-02 1994-10-24 Pioneer Hi-Bred International, Inc. Southern corn rootworm control with limonene
CA2118071C (en) * 1993-10-28 2004-09-14 Rodney B. Croteau Dna encoding limonene synthase from mentha spicata
US5824774A (en) * 1996-04-12 1998-10-20 Board Of Trustees Of The University Of Kentucky Chimeric isoprenoid synthases and uses thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013162776A (ja) * 2012-02-13 2013-08-22 Sumitomo Rubber Ind Ltd イソプレノイドの製造方法、及びイソプレノイド

Also Published As

Publication number Publication date
GR990300025T1 (en) 1999-07-30
DE69715192T2 (de) 2003-04-30
ZA973108B (en) 1997-11-04
EP0904095B1 (en) 2002-09-04
ID19769A (id) 1998-07-30
CZ317998A3 (cs) 1999-02-17
DE904095T1 (de) 1999-10-07
OA10895A (en) 2001-10-11
JP2015171387A (ja) 2015-10-01
CA2250712C (en) 2008-07-08
JP2012005499A (ja) 2012-01-12
ES2132046T3 (es) 2003-03-16
ES2132046T1 (es) 1999-08-16
IN186316B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2001-08-04
EP0904095A1 (en) 1999-03-31
AU2726497A (en) 1997-11-07
AP808A (en) 2000-02-29
IL126486A0 (en) 1999-08-17
AP9700971A0 (en) 1997-07-31
ATE223225T1 (de) 2002-09-15
TW509724B (en) 2002-11-11
DE69715192D1 (de) 2002-10-10
KR20000005385A (ko) 2000-01-25
EP1229122A2 (en) 2002-08-07
HK1017275A1 (en) 1999-11-19
EP0904095A4 (en) 1999-07-07
PT904095E (pt) 2002-12-31
CZ294613B6 (cs) 2005-02-16
TR199802043T2 (xx) 1999-01-18
PL329404A1 (en) 1999-03-29
CA2250712A1 (en) 1997-10-23
EA001622B1 (ru) 2001-06-25
EP1229122A3 (en) 2002-10-09
BR9708650A (pt) 1999-08-03
WO1997038703A1 (en) 1997-10-23
EA199800917A1 (ru) 1999-04-29
US5824774A (en) 1998-10-20
US6072045A (en) 2000-06-06
JP2015057074A (ja) 2015-03-26
AR006638A1 (es) 1999-09-08
IL126486A (en) 2006-04-10

Similar Documents

Publication Publication Date Title
JP2000508899A (ja) キメライソプレノイド合成酵素およびその使用
US8354504B2 (en) Chimeric isoprenoid synthases and uses thereof
US7186891B1 (en) Plant cells and plants expressing chimeric isoprenoid synthases
WO1997038703A9 (en) Chimeric isoprenoid synthases and uses thereof
AU2018216169B2 (en) Expression of nitrogenase polypeptides in plant cells
JP2002529077A (ja) イチイのゲラニルゲラニル二リン酸シンターゼをコードする核酸、及び使用方法。
EP2718309B1 (en) Transcription factor modulating terpene biosynthesis
KR102410996B1 (ko) 식물 세포에서 감수분열의 염색체 교차 재조합을 증가시키는 Protein phosphatase 4 복합체 및 이의 용도
US10550409B2 (en) Drimenol synthases III
CN109897860B (zh) 小麦UDP-葡萄糖基转移酶TaUGT6及其应用
Chappell et al. Chimeric Isoprenoid Synthases and Uses Thereof
WO2025080679A9 (en) Methods and compositions for making ketocarotenoids
WO2025080679A1 (en) Methods and compositions for making ketocarotenoids
HK1017275B (en) Chimeric isoprenoid synthases and uses thereof
CH OH y—CHACONINE

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20040315

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060822

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20061120

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20070122

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070221

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20080311

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080703

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20080611

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110524

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110530

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20110906