JP2000507950A5 - - Google Patents

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Publication number
JP2000507950A5
JP2000507950A5 JP1997534907A JP53490797A JP2000507950A5 JP 2000507950 A5 JP2000507950 A5 JP 2000507950A5 JP 1997534907 A JP1997534907 A JP 1997534907A JP 53490797 A JP53490797 A JP 53490797A JP 2000507950 A5 JP2000507950 A5 JP 2000507950A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997534907A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000507950A (ja
JP4118337B2 (ja
Filing date
Publication date
Priority claimed from GBGB9606508.1A external-priority patent/GB9606508D0/en
Priority claimed from GBGB9623001.6A external-priority patent/GB9623001D0/en
Application filed filed Critical
Priority claimed from PCT/EP1997/001530 external-priority patent/WO1997036903A1/en
Publication of JP2000507950A publication Critical patent/JP2000507950A/ja
Publication of JP2000507950A5 publication Critical patent/JP2000507950A5/ja
Application granted granted Critical
Publication of JP4118337B2 publication Critical patent/JP4118337B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP53490797A 1996-03-28 1997-03-26 好中球エラスターゼのインヒビターとしてのピロロピロロン誘導体 Expired - Fee Related JP4118337B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9606508.1 1996-03-28
GBGB9606508.1A GB9606508D0 (en) 1996-03-28 1996-03-28 Chemical componds
GBGB9623001.6A GB9623001D0 (en) 1996-11-05 1996-11-05 Chemical compounds
GB9623001.6 1996-11-05
PCT/EP1997/001530 WO1997036903A1 (en) 1996-03-28 1997-03-26 Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase

Publications (3)

Publication Number Publication Date
JP2000507950A JP2000507950A (ja) 2000-06-27
JP2000507950A5 true JP2000507950A5 (enExample) 2006-02-02
JP4118337B2 JP4118337B2 (ja) 2008-07-16

Family

ID=26309008

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53490797A Expired - Fee Related JP4118337B2 (ja) 1996-03-28 1997-03-26 好中球エラスターゼのインヒビターとしてのピロロピロロン誘導体

Country Status (30)

Country Link
US (3) US5994344A (enExample)
EP (1) EP0891362B1 (enExample)
JP (1) JP4118337B2 (enExample)
KR (1) KR20000005039A (enExample)
CN (1) CN1067075C (enExample)
AP (1) AP823A (enExample)
AR (1) AR006401A1 (enExample)
AT (1) ATE261969T1 (enExample)
AU (1) AU726649B2 (enExample)
BR (1) BR9708449A (enExample)
CA (1) CA2250209A1 (enExample)
CO (1) CO4790152A1 (enExample)
CZ (1) CZ309798A3 (enExample)
DE (1) DE69728139T2 (enExample)
DK (1) DK0891362T3 (enExample)
EA (1) EA001437B1 (enExample)
EE (1) EE9800335A (enExample)
ES (1) ES2217404T3 (enExample)
HU (1) HUP9900567A3 (enExample)
IL (1) IL125859A0 (enExample)
IS (1) IS4837A (enExample)
NO (1) NO984470L (enExample)
NZ (1) NZ331490A (enExample)
PE (1) PE55298A1 (enExample)
PL (1) PL329153A1 (enExample)
PT (1) PT891362E (enExample)
SK (1) SK132498A3 (enExample)
TR (1) TR199801935T2 (enExample)
WO (1) WO1997036903A1 (enExample)
YU (1) YU41198A (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9719189D0 (en) * 1997-09-09 1997-11-12 Glaxo Group Ltd New therapeutic method
GB9719172D0 (en) 1997-09-09 1997-11-12 Glaxo Group Ltd Compounds
PE107899A1 (es) * 1997-09-09 1999-11-17 Glaxo Group Ltd Derivados de pirrolopirrolona como inhibidores de elastasa leucocitaria
GB9719187D0 (en) * 1997-09-09 1997-11-12 Glaxo Group Ltd Compounds
GB9821199D0 (en) * 1998-09-30 1998-11-25 Glaxo Group Ltd Chemical compounds
GB9905418D0 (en) * 1999-03-09 1999-05-05 Glaxo Group Ltd Process
WO2004081015A1 (en) * 2003-03-10 2004-09-23 Hetero Drugs Limited Amorphous clopidogrel hydrogen sulfate
WO2004080966A1 (ja) 2003-03-14 2004-09-23 Ono Pharmaceutical Co., Ltd. 含窒素複素環誘導体およびそれらを有効成分とする薬剤
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7692037B2 (en) * 2004-09-02 2010-04-06 Eastman Chemical Company Optimized liquid-phase oxidation
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
NZ553696A (en) 2004-09-13 2010-02-26 Ono Pharmaceutical Co Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient
GB0512238D0 (en) * 2005-06-15 2005-07-27 Univ Cambridge Tech Anti-inflammatory agents
WO2007105637A1 (ja) 2006-03-10 2007-09-20 Ono Pharmaceutical Co., Ltd. 含窒素複素環誘導体およびそれらを有効成分とする薬剤
CN104758281A (zh) * 2007-04-23 2015-07-08 西佳技术公司 用于治疗和预防正痘病毒感染和相关疾病的化合物、组合物和方法
JP5544296B2 (ja) 2007-11-16 2014-07-09 ライジェル ファーマシューティカルズ, インコーポレイテッド 代謝障害のためのカルボキサミド、スルホンアミド、およびアミン化合物
ES2553340T3 (es) 2007-12-12 2015-12-07 Rigel Pharmaceuticals, Inc. Compuestos de carboxamida, sulfonamida y amina para trastornos metabólicos
JP5658138B2 (ja) 2008-04-23 2015-01-21 ライジェル ファーマシューティカルズ, インコーポレイテッド 代謝障害の処置のためのカルボキサミド化合物
PT2935274T (pt) * 2012-12-18 2018-12-05 Chiesi Farm Spa Derivados de 3-oxo-2,3,5,8-tetrahidro-[1,2,4]triazolo[4,3- a]pirimidina para o tratamento de doenças respiratórias
WO2021053058A1 (en) 2019-09-17 2021-03-25 Mereo Biopharma 4 Limited Alvelestat for use in the treatment of graft rejection, bronchiolitis obliterans syndrome and graft versus host disease
LT4106757T (lt) 2020-04-16 2023-11-10 Mereo Biopharma 4 Limited Neutrofilų elastazės inhibitoriaus alvelestato panaudojimas kvėpavimo sistemos ligų, nulemtų alfa-1 antitripsino nepakankamumo, gydymui
JP2024540952A (ja) 2021-10-20 2024-11-06 メレオ バイオファーマ 4 リミテッド 線維化の治療における使用のための好中球エラスターゼ阻害剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2932650A (en) * 1957-11-19 1960-04-12 Arthur C Cope 2-6-diazabicyclo (3. 3. 0) octanes
US4997950A (en) * 1989-04-20 1991-03-05 Richard Finbar Murphy Novel C-terminal gastrin antagonists
GB9211783D0 (en) * 1992-06-04 1992-07-15 Ici Plc Amide derivatives
GB9402680D0 (en) * 1994-02-11 1994-04-06 Zeneca Ltd Pyrrolidine derivatives
US5610296A (en) * 1994-12-05 1997-03-11 G. D. Searle & Co. Process for the preparation of amidino phenyl pyrrolidine beta-alanine urea analogs

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