JP2000503591A - 霧化装置及びその方法 - Google Patents

霧化装置及びその方法

Info

Publication number
JP2000503591A
JP2000503591A JP9540553A JP54055397A JP2000503591A JP 2000503591 A JP2000503591 A JP 2000503591A JP 9540553 A JP9540553 A JP 9540553A JP 54055397 A JP54055397 A JP 54055397A JP 2000503591 A JP2000503591 A JP 2000503591A
Authority
JP
Japan
Prior art keywords
liquid
atomizing
gas
outlet
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP9540553A
Other languages
English (en)
Japanese (ja)
Inventor
カルボ，アルフォンソ ガンナン
リポール，アントニオ バレロ
Original Assignee
ユニバーシィダッド デ セヴィラ，ヴィセレクトラド デ インベスティゲーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ユニバーシィダッド デ セヴィラ，ヴィセレクトラド デ インベスティゲーション filed Critical ユニバーシィダッド デ セヴィラ，ヴィセレクトラド デ インベスティゲーション
Publication of JP2000503591A publication Critical patent/JP2000503591A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0441—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber
    • B05B7/0475—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber with means for deflecting the peripheral gas flow towards the central liquid flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/06—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/061—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with several liquid outlets discharging one or several liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/06—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/062—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet
    • B05B7/065—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet an inner gas outlet being surrounded by an annular adjacent liquid outlet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/06—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/062—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet
    • B05B7/066—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet with an inner liquid outlet surrounded by at least one annular gas outlet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B05B7/0884—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point the outlet orifices for jets constituted by a liquid or a mixture containing a liquid being aligned
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02M—SUPPLYING COMBUSTION ENGINES IN GENERAL WITH COMBUSTIBLE MIXTURES OR CONSTITUENTS THEREOF
    • F02M43/00—Fuel-injection apparatus operating simultaneously on two or more fuels, or on a liquid fuel and another liquid, e.g. the other liquid being an anti-knock additive
    • F02M43/04—Injectors peculiar thereto
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02M—SUPPLYING COMBUSTION ENGINES IN GENERAL WITH COMBUSTIBLE MIXTURES OR CONSTITUENTS THEREOF
    • F02M67/00—Apparatus in which fuel-injection is effected by means of high-pressure gas, the gas carrying the fuel into working cylinders of the engine, e.g. air-injection type
    • F02M67/10—Injectors peculiar thereto, e.g. valve less type
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02M—SUPPLYING COMBUSTION ENGINES IN GENERAL WITH COMBUSTIBLE MIXTURES OR CONSTITUENTS THEREOF
    • F02M69/00—Low-pressure fuel-injection apparatus ; Apparatus with both continuous and intermittent injection; Apparatus injecting different types of fuel
    • F02M69/04—Injectors peculiar thereto
    • F02M69/047—Injectors peculiar thereto injectors with air chambers, e.g. communicating with atmosphere for aerating the nozzles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F23—COMBUSTION APPARATUS; COMBUSTION PROCESSES
    • F23D—BURNERS
    • F23D11/00—Burners using a direct spraying action of liquid droplets or vaporised liquid into the combustion space
    • F23D11/10—Burners using a direct spraying action of liquid droplets or vaporised liquid into the combustion space the spraying being induced by a gaseous medium, e.g. water vapour
    • F23D11/106—Burners using a direct spraying action of liquid droplets or vaporised liquid into the combustion space the spraying being induced by a gaseous medium, e.g. water vapour medium and fuel meeting at the burner outlet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/02—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops, or having an outlet of particular shape

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Nozzles (AREA)
  • Fuel-Injection Apparatus (AREA)
  • Special Spraying Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
JP9540553A 1996-05-13 1997-02-18 霧化装置及びその方法 Withdrawn JP2000503591A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009601101A ES2140998B1 (es) 1996-05-13 1996-05-13 Procedimiento de atomizacion de liquidos.
ES9601101 1996-05-13
PCT/ES1997/000034 WO1997043048A1 (fr) 1996-05-13 1997-02-18 Procede d'atomisation de liquides

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2003014024A Division JP2004000904A (ja) 1996-05-13 2003-01-22 粒子の製造方法およびその製造方法に製造された粒子並びに液滴の製造装置
JP2004083760A Division JP3664404B2 (ja) 1996-05-13 2004-03-23 液滴の製造方法

Publications (1)

Publication Number Publication Date
JP2000503591A true JP2000503591A (ja) 2000-03-28

Family

ID=8294847

Family Applications (3)

Application Number Title Priority Date Filing Date
JP9540553A Withdrawn JP2000503591A (ja) 1996-05-13 1997-02-18 霧化装置及びその方法
JP2003014024A Pending JP2004000904A (ja) 1996-05-13 2003-01-22 粒子の製造方法およびその製造方法に製造された粒子並びに液滴の製造装置
JP2004083760A Expired - Fee Related JP3664404B2 (ja) 1996-05-13 2004-03-23 液滴の製造方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2003014024A Pending JP2004000904A (ja) 1996-05-13 2003-01-22 粒子の製造方法およびその製造方法に製造された粒子並びに液滴の製造装置
JP2004083760A Expired - Fee Related JP3664404B2 (ja) 1996-05-13 2004-03-23 液滴の製造方法

Country Status (7)

Country Link
US (3) US6119953A (fr)
EP (1) EP0899017B1 (fr)
JP (3) JP2000503591A (fr)
CA (1) CA2254969C (fr)
DE (1) DE69714583T2 (fr)
ES (2) ES2140998B1 (fr)
WO (1) WO1997043048A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013519503A (ja) * 2010-02-10 2013-05-30 ゾレッジ‐ガレトン，アルフレド 液体にプラズマ粒子を当てるための方法及び装置、並びに水を殺菌するための使用

Families Citing this family (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6189803B1 (en) 1996-05-13 2001-02-20 University Of Seville Fuel injection nozzle and method of use
US6792940B2 (en) * 1996-05-13 2004-09-21 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6197835B1 (en) * 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for creating spherical particles of uniform size
ES2158741B1 (es) * 1997-12-17 2002-03-16 Univ Sevilla Dispositivo de sipersion de un fluido en otro inmiscible en forma de microgotas o microburbujas de tamaño uniforme.
US6299145B1 (en) 1996-05-13 2001-10-09 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6187214B1 (en) * 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6595202B2 (en) 1996-05-13 2003-07-22 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6196525B1 (en) 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6386463B1 (en) 1996-05-13 2002-05-14 Universidad De Sevilla Fuel injection nozzle and method of use
US6405936B1 (en) 1996-05-13 2002-06-18 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US6248378B1 (en) * 1998-12-16 2001-06-19 Universidad De Sevilla Enhanced food products
ES2140998B1 (es) 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
DE69806504T2 (de) * 1997-12-17 2003-02-27 Universidad De Sevilla, Sevilla Verfahren zur erzeugung von hohlen tröpfchen
AU745904B2 (en) * 1997-12-17 2002-04-11 Universidad De Sevilla Device and method for creating spherical particles of uniform size
WO1999030831A1 (fr) * 1997-12-17 1999-06-24 Universidad De Sevilla Injecteur et son procede d'utilisation
US6234167B1 (en) * 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6450189B1 (en) 1998-11-13 2002-09-17 Universidad De Sevilla Method and device for production of components for microfabrication
ES2424713T4 (es) * 1999-06-11 2014-01-23 Aradigm Corporation Método para producir un aerosol
US20060169800A1 (en) * 1999-06-11 2006-08-03 Aradigm Corporation Aerosol created by directed flow of fluids and devices and methods for producing same
US6576191B1 (en) * 1999-09-30 2003-06-10 Therox, Inc. Apparatus for blood oxygenation
US6860434B2 (en) * 2000-04-18 2005-03-01 Kang Ho Ahn Apparatus for manufacturing ultra-fine particles using electrospray device and method thereof
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
AU2001277230A1 (en) * 2000-08-01 2002-02-13 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution andparticles made thereby
AU2001284982A1 (en) * 2000-08-15 2002-02-25 Board Of Trustees Of The University Of Illinois Method of forming microparticles
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6701921B2 (en) * 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US7077130B2 (en) * 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6761109B2 (en) 2001-03-28 2004-07-13 The Boc Group, Inc. Apparatus and method for mixing a gas and a liquid
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) * 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
GB2384198B (en) 2002-01-18 2005-03-02 Profile Drug Delivery Ltd Nebulizer metering
DE60320383D1 (de) * 2002-02-04 2008-05-29 Univ Sevilla Vorrichtung zur erzeugung kapillarer strahlen und mikro- und nanometerteilchen
US6871792B2 (en) * 2002-03-22 2005-03-29 Chrysalis Technologies Incorporated Apparatus and method for preparing and delivering fuel
US6779513B2 (en) * 2002-03-22 2004-08-24 Chrysalis Technologies Incorporated Fuel injector for an internal combustion engine
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US6889690B2 (en) * 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US7677411B2 (en) 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
US6958848B2 (en) 2002-05-23 2005-10-25 E Ink Corporation Capsules, materials for use therein and electrophoretic media and displays containing such capsules
US7008658B2 (en) 2002-05-29 2006-03-07 The Boc Group, Inc. Apparatus and method for providing treatment to a continuous supply of food product by impingement
JP2006507921A (ja) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
DE10234165B4 (de) * 2002-07-26 2008-01-03 Advanced Micro Devices, Inc., Sunnyvale Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material
US7297179B2 (en) * 2002-09-30 2007-11-20 Fujifilm Corporation Method of producing metal particles, and metal oxide obtained from the particles
GB2396825B (en) * 2002-11-20 2004-12-08 Profile Respiratory Systems Lt Improved inhalation method and apparatus
GB2395437C (en) * 2002-11-20 2010-10-20 Profile Respiratory Systems Ltd Improved inhalation method and apparatus
KR20050088243A (ko) 2002-12-30 2005-09-02 넥타르 테라퓨틱스 프리필름화 분무기
US6779413B1 (en) * 2003-03-06 2004-08-24 Fm Global Technologies Llc Clean room fire simulation
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
EP1610888A2 (fr) 2003-04-10 2006-01-04 President And Fellows Of Harvard College Formation et regulation d'especes fluidiques
WO2004112799A1 (fr) * 2003-06-13 2004-12-29 Chrysalis Technologies Incorporated Procedes et appareils de production de particules nanometriques
EP2662135A3 (fr) 2003-08-27 2013-12-25 President and Fellows of Harvard College Méthode de mélange de gouttelettes dans un microcanal
US7309500B2 (en) * 2003-12-04 2007-12-18 The Board Of Trustees Of The University Of Illinois Microparticles
DE102004009386A1 (de) * 2004-02-24 2005-09-08 Cavis Microcaps Gmbh Gerät und Anordnung zur Erzeugung von Einzeltropfen aus Flüssigkeiten unterschiedlicher Viskosität in gasförmigen und/oder flüssigen Medien
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
ES2257151B1 (es) * 2004-05-20 2007-07-16 Universidad De Sevilla Dispositivo y procedimiento para romper gotas y burbujas de tamaño milimetrico y micrometrico.
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
ES2264608B2 (es) * 2004-09-30 2007-08-16 Universidad De Sevilla Dispositivo y procedimiento para la atomizacion neumatica de liquidos mediante flujo implosivo de gas.
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2006042297A2 (fr) * 2004-10-12 2006-04-20 Aradigm Corporation Dispositif et procede de generation d'un aerosol a partir d'une formulation liquide et assurant la sterilite de cette formulation
US7748343B2 (en) 2004-11-22 2010-07-06 The Board Of Trustees Of The University Of Illinois Electrohydrodynamic spraying system
US8201351B2 (en) * 2005-01-17 2012-06-19 Alfonso Miguel Ganan Calvo Procedure and device for the micro-mixing of fluids through reflux cell
WO2006082588A2 (fr) * 2005-02-07 2006-08-10 Pharmalight Inc. Procede et dispositif d'administration ophtalmique d'ingredients pharmaceutiquement actifs
AU2006220816A1 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
US20100137163A1 (en) 2006-01-11 2010-06-03 Link Darren R Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors
CA2640024A1 (fr) * 2006-01-27 2007-08-09 President And Fellows Of Harvard College Coalescence de gouttelettes fluidiques
CA2640508C (fr) 2006-02-13 2014-04-15 Olga Ornatsky Analyse de l'expression d'un gene oligonucleotidique marque par un element
CA2571904A1 (fr) * 2006-02-15 2007-08-15 Fio Corporation Systeme et methode de detection d'agents pathogenes
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2481815B1 (fr) 2006-05-11 2016-01-27 Raindance Technologies, Inc. Dispositifs microfluidiques
US9074242B2 (en) 2010-02-12 2015-07-07 Raindance Technologies, Inc. Digital analyte analysis
WO2008021123A1 (fr) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Tensioactifs fluorocarbonés stabilisateurs d'émulsions
US20090065714A1 (en) * 2006-11-30 2009-03-12 Keady John P Eletrofluid collisional accelerator and fusion reactor
CA2580589C (fr) 2006-12-19 2016-08-09 Fio Corporation Systeme de detection microfluidique
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008116950A1 (fr) * 2007-03-27 2008-10-02 Universidad De Sevilla Procédé de génération de gouttes et de bulles micro et submicrométriques au moyen de co-flux visqueux
US7776927B2 (en) * 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
CA2682826C (fr) 2007-04-02 2013-08-13 Fio Corporation Systeme et procede de deconvolution de signaux spectraux de fluorescence multiplexes produits par une technique de codage optique par points quantiques
WO2008130623A1 (fr) 2007-04-19 2008-10-30 Brandeis University Manipulation de fluides, composants fluidiques et réactions dans des systèmes microfluidiques
WO2009000084A1 (fr) 2007-06-22 2008-12-31 Fio Corporation Systèmes et procédés pour fabriquer un polymère dopé par des points quantiques
EP2174115B1 (fr) 2007-07-09 2013-08-28 Fio Corporation Systèmes et procédés pour améliorer la détection de fluorescence de molécules cibles dans un échantillon de test
SG183034A1 (en) * 2007-07-23 2012-08-30 Fio Corp A method and system for collating, storing, analyzing and enabling access to collected and analyzed data associated with biological and environmental test subjects
EP2209549A4 (fr) 2007-10-12 2014-03-05 Fio Corp Procédé de focalisation d'écoulement et système de création de volumes concentrés de microbilles, et microbilles formées à la suite de celui-ci
US8876022B2 (en) * 2008-04-11 2014-11-04 Postech Academy—Industry Foundation Droplet discharge head and droplet discharge apparatus
KR20090109222A (ko) * 2008-04-15 2009-10-20 삼성전기주식회사 디스펜서
US9091434B2 (en) * 2008-04-18 2015-07-28 The Board Of Trustees Of The University Of Alabama Meso-scaled combustion system
CA2729023C (fr) 2008-06-25 2013-02-26 Fio Corporation Systeme d'avertissement de menace biologique
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP2315629B1 (fr) * 2008-07-18 2021-12-15 Bio-Rad Laboratories, Inc. Bibliothèque de gouttelettes
CN105759021A (zh) 2008-08-29 2016-07-13 Fio公司 用于检测生物和环境检测样品的一次性手持式诊断检测设备和相关系统与方法
CN102348986B (zh) 2009-01-13 2015-05-06 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备和方法
EP3415235A1 (fr) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation de gouttelettes microfluidiques
CN102574078B (zh) 2009-09-02 2016-05-18 哈佛学院院长等 使用喷射和其它技术产生的多重乳液
WO2011042564A1 (fr) 2009-10-09 2011-04-14 Universite De Strasbourg Nanomatériau marqué à base de silice à propriétés améliorées et ses utilisations
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
CN102971069A (zh) * 2010-03-17 2013-03-13 哈佛学院院长等 熔体乳化
ES2406630B1 (es) * 2010-03-18 2014-04-24 Universidad De Sevilla Metodo para el control de la irradiacion solar sobre la superficie terrestre mediante la dispersion controlada de aerosoles
EP3409314B1 (fr) 2010-08-24 2020-12-30 Trudell Medical International Dispositif de distribution d'aérosol
EP3447155A1 (fr) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Dosages en sandwich dans des gouttelettes
EP3412778A1 (fr) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Procédés permettant de former des gouttelettes mélangées
CA2767773C (fr) 2011-02-11 2015-11-24 Grain Processing Corporation Composition comprenant un sel et un agent d'interruption de cristallisation
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
EP2714254B1 (fr) 2011-05-23 2017-09-06 President and Fellows of Harvard College Génération d'émulsions et, notamment, d'émulsions multiples
US9556470B2 (en) 2011-06-02 2017-01-31 Raindance Technologies, Inc. Enzyme quantification
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
WO2013006661A2 (fr) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Émulsions multiples et techniques de formation d'émulsions multiples
GB2492831A (en) 2011-07-14 2013-01-16 Hkpb Scient Ltd Workpiece surface modification during ultrasonic peening
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US8955325B1 (en) 2011-08-31 2015-02-17 The United States Of America, As Represented By The Secretary Of The Navy Charged atomization of fuel for increased combustion efficiency in jet engines
CN102500489A (zh) * 2011-11-06 2012-06-20 中国科学技术大学 一种可实现微细雾化的喷枪喷头
ES2444021B1 (es) * 2012-02-22 2014-10-21 Universidad De Sevilla Procedimiento y dispositivo para microfabricación y micro-soldadura
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (fr) 2013-12-31 2015-07-09 Raindance Technologies, Inc. Système et procédé de détection d'une espèce d'arn
EP2962751B1 (fr) 2014-07-03 2017-04-05 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Procédé de formation de gouttelettes dans un système à phases multiples
JP6866296B2 (ja) 2015-02-27 2021-04-28 ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System ポリペプチド治療及びその使用
DE102015206843A1 (de) 2015-04-16 2016-10-20 Hte Gmbh The High Throughput Experimentation Company Vorrichtung und Verfahren zum Versprühen von Flüssigkeiten und der Erzeugung von Feinstnebel
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
JP6840468B2 (ja) * 2016-03-29 2021-03-10 三菱重工業株式会社 ガスタービン燃焼器
US9573147B1 (en) 2016-04-15 2017-02-21 Kaer Biotherapeutics Corporation Aerosolizing nozzle and method of operating such aerosolizing nozzle
US10654040B2 (en) 2016-08-18 2020-05-19 Northeastern University Platform for liquid droplet formation and isolation
US10443838B2 (en) * 2017-04-05 2019-10-15 Hall Labs Llc Method for forming consistently-sized and controllably-timed droplets
US10969350B2 (en) 2017-05-22 2021-04-06 Arizona Board Of Regents On Behalf Of Arizona Stat Metal electrode based 3D printed device for tuning microfluidic droplet generation frequency and synchronizing phase for serial femtosecond crystallography
US11173487B2 (en) 2017-12-19 2021-11-16 Arizona Board Of Regents On Behalf Of Arizona State University Deterministic ratchet for sub-micrometer bioparticle separation
US10369579B1 (en) 2018-09-04 2019-08-06 Zyxogen, Llc Multi-orifice nozzle for droplet atomization
JP7496826B2 (ja) 2018-09-10 2024-06-07 ラング セラピューティクス，エルエルシー Ｃａｖ－１タンパク質の修飾ペプチドフラグメント及び線維症の治療におけるその使用
US11318487B2 (en) * 2019-05-14 2022-05-03 Arizona Board Of Regents On Behalf Of Arizona State University Co-flow injection for serial crystallography
US11624718B2 (en) 2019-05-14 2023-04-11 Arizona Board Of Regents On Behalf Of Arizona State University Single piece droplet generation and injection device for serial crystallography
WO2021191266A1 (fr) 2020-03-25 2021-09-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Aérosolisation de hdl pour traiter des infections pulmonaires
EP3892275A1 (fr) 2020-04-08 2021-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Production d'aérosols de hcq ou de ses métabolites pour le traitement d'infections pulmonaires
GB202103194D0 (en) * 2020-06-23 2021-04-21 Micromass Ltd Nebuliser outlet
US11485632B2 (en) 2020-10-09 2022-11-01 Arizona Board Of Regents On Behalf Of Arizona State University Modular 3-D printed devices for sample delivery and method

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB652206A (en) * 1948-01-02 1951-04-18 Charles Reinhold Improvements in or relating to nozzles for spray guns
FR1011655A (fr) * 1949-02-25 1952-06-25 Pierre Bevengut Ets Bec atomiseur
CS153231B1 (fr) * 1970-11-18 1974-02-25
DE7206538U (de) * 1971-03-01 1972-10-26 The Perkin-Elmer Corp Zerstaeuber
US3804255A (en) * 1972-10-18 1974-04-16 R Speece Recycling gas contact apparatus
CH563807A5 (en) * 1973-02-14 1975-07-15 Battelle Memorial Institute Fine granules and microcapsules mfrd. from liquid droplets - partic. of high viscosity requiring forced sepn. of droplets
JPS5254583A (en) 1975-10-29 1977-05-04 Hitachi Ltd Method of encasing electronic parts in magazine
US4162282A (en) * 1976-04-22 1979-07-24 Coulter Electronics, Inc. Method for producing uniform particles
US4141055A (en) * 1977-04-27 1979-02-20 Bell Telephone Laboratories, Incorporated Crossover structure for microelectronic circuits
US4347935A (en) * 1979-05-16 1982-09-07 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for electrostatically sorting biological cells
DE3005857A1 (de) * 1980-02-16 1981-09-10 Robert Bosch Gmbh, 7000 Stuttgart Kraftstoffeinspritzduese
US4352789A (en) * 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
CA1166413A (fr) * 1980-10-30 1984-05-01 Edward E. Timm Methode et dispositif pour la preparation de perles de polymere dimensionnellement uniformes
DE3105686A1 (de) * 1981-02-17 1982-09-02 Robert Bosch Gmbh, 7000 Stuttgart "kraftstoffeinspritzduese"
DE3217887A1 (de) * 1981-05-15 1982-12-02 Kabushiki Kaisha Komatsu Seisakusho, Tokyo Kraftstoff-einspritzsystem fuer brennkraftmaschinen
EP0083348B1 (fr) * 1981-07-07 1986-11-05 Piper Fm Limited Alimentation en carburant pour moteurs a combustion interne
JPS59174561A (ja) * 1983-03-18 1984-10-03 三井造船株式会社 多孔質セラミツクスの製造方法
US4603671A (en) * 1983-08-17 1986-08-05 Nippon Soken, Inc. Fuel injector for an internal combustion engine
CA1235367A (fr) * 1984-04-05 1988-04-19 Gary J. Green Methode et dispositif pour engendrer des gouttelettes uniformes
US4717049A (en) * 1984-04-05 1988-01-05 Mobil Oil Corporation Droplet generating apparatus
US4781968A (en) * 1986-02-28 1988-11-01 Digital Equipment Corporation Micro-electronics devices and methods of manufacturing same
JPS62289257A (ja) * 1986-06-09 1987-12-16 Ikeuchi:Kk 超微霧噴射ノズル
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
AU592033B2 (en) * 1987-01-21 1989-12-21 Michael Nicolaas Aloysius Noordermeer One-piece high-solids nebulizer
US4787404A (en) * 1987-06-12 1988-11-29 International Business Machines Corporation Low flow rate-low pressure atomizer device
DE3724156A1 (de) * 1987-07-22 1989-02-02 Norddeutsche Affinerie Verfahren zum herstellen von metallischen oder keramischen hohlkugeln
US5167798A (en) * 1988-01-27 1992-12-01 Virginia Tech Intellectual Properties, Inc. Apparatus and process for the separation of hydrophobic and hydrophilic particles using microbubble column flotation together with a process and apparatus for generation of microbubbles
EP0445169A1 (fr) * 1988-11-22 1991-09-11 Dunne Miller Weston Limited Dispositif permettant de melanger un gaz et un liquide
DE3844365A1 (de) * 1988-12-30 1990-07-05 Bosch Gmbh Robert Kraftstoffeinspritzvorrichtung
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
FR2645456B1 (fr) * 1989-04-11 1994-02-11 Air Liquide Procede et installation de traitement d'un liquide avec un gaz
JPH03169331A (ja) * 1989-11-30 1991-07-23 Fuji Debuison Kagaku Kk エマルシヨンの調製方法
JPH05507439A (ja) * 1990-05-30 1993-10-28 ワイヤーハウザー　カンパニー 材料を気体に被覆する装置
US5077176A (en) * 1990-07-30 1991-12-31 At&T Bell Laboratories Pre-plate cleaning process
TW226977B (fr) * 1990-09-06 1994-07-21 Teijin Ltd
GB2248031B (en) * 1990-09-19 1994-07-06 Yakuzky Ni I Pi Almazodobyva Flotation machine
US5194915A (en) * 1990-09-20 1993-03-16 Millipore Corporation Photometric apparatus and process
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
GB2255291A (en) * 1991-05-03 1992-11-04 Exxon Research Engineering Co Bitumen emulsions.
US5230850A (en) * 1991-05-16 1993-07-27 Lewis Raymond O Fan blade reinforcement using bonded hollow spheres
ES2141108T3 (es) * 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
US5180465A (en) * 1991-07-22 1993-01-19 Nippon Cmk Corp. Etching method of forming microcircuit patterns on a printed circuit board
DE4128590A1 (de) * 1991-08-28 1993-03-04 Kumag Ag Verfahren zum auftragen von druckfarbe und dafuer geeigneter druckkopf
US5174247A (en) * 1992-01-22 1992-12-29 Mitsubishi Jukogyo Kabushiki Kaisha Water injection diesel engine
US5554646A (en) * 1992-04-29 1996-09-10 Wisconsin Alumni Research Foundation Method for reducing body fat in animals
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
BR9307399A (pt) * 1992-11-06 1999-08-31 Patrick Sundholm Processo e aparelho para revestir papel ou assemelhado
US5378355A (en) * 1992-12-04 1995-01-03 Water Pollution Control Corporation Direct delivery in-situ diffuser cleaning
US5364838A (en) * 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
GB9306290D0 (en) * 1993-03-26 1993-05-19 Exxon Research Engineering Co Bituminous surface construction
GB9403702D0 (en) * 1994-02-25 1994-04-13 Flow Research Evaluation Diagn Improvements relating to spray generators
US5458292A (en) * 1994-05-16 1995-10-17 General Electric Company Two-stage fuel injection nozzle
US5464157A (en) * 1994-07-18 1995-11-07 The Perkin-Elmer Corporation Nebulizer for use in an atomic absorption system
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
GB9423618D0 (en) * 1994-11-23 1995-01-11 North West Water Group Plc Optical instrument
US5725153A (en) * 1995-01-10 1998-03-10 Georgia Tech Research Corporation Oscillating capillary nebulizer
US5697341A (en) * 1995-11-20 1997-12-16 Caterpillar, Inc. Fill metered hydraulically actuated fuel injection system and method of fuel injection
US5752663A (en) * 1996-01-26 1998-05-19 Hewlett-Packard Company Micro concentric tube nebulizer for coupling liquid devices to chemical analysis devices
US5868322A (en) * 1996-01-31 1999-02-09 Hewlett-Packard Company Apparatus for forming liquid droplets having a mechanically fixed inner microtube
ES2140998B1 (es) * 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
US5884846A (en) * 1996-09-19 1999-03-23 Tan; Hsiaoming Sherman Pneumatic concentric nebulizer with adjustable and capillaries

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013519503A (ja) * 2010-02-10 2013-05-30 ゾレッジ‐ガレトン，アルフレド 液体にプラズマ粒子を当てるための方法及び装置、並びに水を殺菌するための使用

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CA2254969A1 (fr) 1997-11-20
US6174469B1 (en) 2001-01-16
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WO1997043048A1 (fr) 1997-11-20
ES2180931T3 (es) 2003-02-16
ES2140998A1 (es) 2000-03-01
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DE69714583T2 (de) 2003-04-03

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