JP2000502320A5 - - Google Patents

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Publication number
JP2000502320A5
JP2000502320A5 JP1997506287A JP50628797A JP2000502320A5 JP 2000502320 A5 JP2000502320 A5 JP 2000502320A5 JP 1997506287 A JP1997506287 A JP 1997506287A JP 50628797 A JP50628797 A JP 50628797A JP 2000502320 A5 JP2000502320 A5 JP 2000502320A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997506287A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000502320A (ja
JP3920919B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP1996/003129 external-priority patent/WO1997004005A2/de
Publication of JP2000502320A publication Critical patent/JP2000502320A/ja
Publication of JP2000502320A5 publication Critical patent/JP2000502320A5/ja
Application granted granted Critical
Publication of JP3920919B2 publication Critical patent/JP3920919B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50628797A 1995-07-17 1996-07-17 抗−hiv−作用を有するシクロスポリン誘導体 Expired - Fee Related JP3920919B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95111162.4 1995-07-17
EP95111162 1995-07-17
PCT/EP1996/003129 WO1997004005A2 (de) 1995-07-17 1996-07-17 Cyclosporin-derivate mit anti-hiv-wirkung

Publications (3)

Publication Number Publication Date
JP2000502320A JP2000502320A (ja) 2000-02-29
JP2000502320A5 true JP2000502320A5 (enExample) 2004-08-19
JP3920919B2 JP3920919B2 (ja) 2007-05-30

Family

ID=8219438

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50628797A Expired - Fee Related JP3920919B2 (ja) 1995-07-17 1996-07-17 抗−hiv−作用を有するシクロスポリン誘導体

Country Status (17)

Country Link
US (1) US5948884A (enExample)
EP (1) EP0842191B1 (enExample)
JP (1) JP3920919B2 (enExample)
KR (1) KR100441220B1 (enExample)
CN (1) CN1141317C (enExample)
AT (1) ATE209216T1 (enExample)
AU (1) AU722858B2 (enExample)
BR (1) BR9609795A (enExample)
CA (1) CA2226880C (enExample)
CZ (1) CZ290754B6 (enExample)
DE (1) DE59608274D1 (enExample)
HU (1) HUP9900405A3 (enExample)
IL (1) IL122754A (enExample)
NO (1) NO980195L (enExample)
NZ (1) NZ315324A (enExample)
PL (1) PL324531A1 (enExample)
WO (1) WO1997004005A2 (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757520B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2762843B1 (fr) * 1997-04-30 1999-12-10 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
US6270957B1 (en) 1997-08-26 2001-08-07 Wisconsin Alumni Research Foundation Non-Imuunosuppressive cyclosporins and their use in the prevention and treatment of HIV infection
AU8918998A (en) * 1997-08-26 1999-03-16 Wisconsin Alumni Research Foundation Non-immunosuppressive cyclosporins and their use in the prevention and treatmentof hiv infection
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
FR2772768B1 (fr) * 1997-12-19 2000-01-14 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
BR9911160A (pt) 1998-06-12 2001-04-03 Chem Ag C Ciclosporinas
ATE312843T1 (de) 1998-07-01 2005-12-15 Debiopharm Sa Neues cyclosporin mit verbesserter wirkung
KR100465012B1 (ko) * 2001-05-11 2005-01-13 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
BRPI0213658A8 (pt) 2001-10-19 2016-12-06 F Hoffmann La Roche Ltd Método para preparar uma mistura isomérica predeterminada ou não dos análogos de ciclosporina a modificados no resíduo de 1-aminoácido, métodopara produzir uma mistura enriquecida com e-isômero ou com z-isômero de análogos de ciclosporina a modificados no resíduo de 1-aminoácido, mistura de (e) e (z)-isômeros, composição, método para a síntese estereoseletiva do z-isômero de isatx247, método para a preparação de aldeído do ciclosporina a
US7108988B2 (en) 2001-11-02 2006-09-19 The J. David Gladstone Institutes Methods of identifying agents for inhibiting lentivirus replication
US6987090B2 (en) * 2002-05-09 2006-01-17 Lg Household & Health Care Ltd. Use of 3-position cyclosporin derivatives for hair growth
EP1603512A2 (en) * 2003-03-17 2005-12-14 Albany Molecular Research, Inc. Novel cyclosporins
EP1804823A4 (en) 2004-09-29 2010-06-09 Amr Technology Inc NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
JP2008514701A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
US7196161B2 (en) * 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
US7361636B2 (en) 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
US7754685B2 (en) * 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
WO2007041631A1 (en) * 2005-09-30 2007-04-12 Scynexis, Inc. ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION
US20070232532A1 (en) * 2006-03-28 2007-10-04 Amr Technology, Inc. Use of cyclosporin alkene analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
ATE502633T1 (de) 2006-05-19 2011-04-15 Scynexis Inc Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
KR101089112B1 (ko) * 2006-06-02 2011-12-06 피씨 제스띠옹 에스.아.에스. 활성 전자 관리
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
US20080255038A1 (en) * 2007-04-11 2008-10-16 Samuel Earl Hopkins Pharmaceutical compositions
WO2009148615A1 (en) * 2008-06-06 2009-12-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
CA2724523A1 (en) * 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
DE102008060549A1 (de) 2008-12-04 2010-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
JP5780969B2 (ja) * 2008-12-31 2015-09-16 サイネクシス,インコーポレーテッド シクロスポリンaの誘導体
CN101874902B (zh) * 2009-06-19 2013-04-03 清华大学 一种用于人工椎间盘髓核假体材料的制备方法
KR20120125610A (ko) 2009-12-30 2012-11-16 싸이넥시스, 인크. 시클로스포린 유사체
CN103153330B (zh) 2010-08-12 2017-08-18 美国科技环球有限公司 新的环孢霉素衍生物在病毒感染的治疗和预防中的应用
ES2625502T3 (es) * 2010-12-03 2017-07-19 S&T Global Inc Nuevos derivados de ciclosporina para el tratamiento y prevención de una infección vírica
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
KR102305423B1 (ko) 2010-12-15 2021-09-27 콘트라빌 파마슈티컬스, 인코퍼레이티드 아미노산 1 및 3에서 변형된 사이클로스포린 유사체 분자
EP2705856A1 (en) 2012-09-07 2014-03-12 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. Compounds for the treatment of neurodegenerative disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US5122511A (en) * 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
FI111730B (fi) * 1990-11-02 2003-09-15 Novartis Ag Menetelmä ei-immunosuppressiivisen syklosporiinin valmistamiseksi

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