JP2000334204A - 凍結濃縮晶析方法 - Google Patents
凍結濃縮晶析方法Info
- Publication number
- JP2000334204A JP2000334204A JP11153746A JP15374699A JP2000334204A JP 2000334204 A JP2000334204 A JP 2000334204A JP 11153746 A JP11153746 A JP 11153746A JP 15374699 A JP15374699 A JP 15374699A JP 2000334204 A JP2000334204 A JP 2000334204A
- Authority
- JP
- Japan
- Prior art keywords
- solution
- ice
- freeze
- heat transfer
- transfer surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002425 crystallisation Methods 0.000 title claims description 31
- 239000013078 crystal Substances 0.000 claims abstract description 58
- 238000012546 transfer Methods 0.000 claims abstract description 34
- 238000000034 method Methods 0.000 claims abstract description 21
- 238000001816 cooling Methods 0.000 claims abstract description 19
- 238000007710 freezing Methods 0.000 claims abstract description 19
- 230000008014 freezing Effects 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000004925 denaturation Methods 0.000 abstract description 4
- 230000036425 denaturation Effects 0.000 abstract description 4
- 239000002904 solvent Substances 0.000 abstract 3
- 230000000452 restraining effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 33
- 230000008025 crystallization Effects 0.000 description 21
- 238000000926 separation method Methods 0.000 description 11
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 8
- 239000002002 slurry Substances 0.000 description 8
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 7
- 150000001413 amino acids Chemical class 0.000 description 7
- 238000003756 stirring Methods 0.000 description 7
- 229930182816 L-glutamine Natural products 0.000 description 6
- 239000002245 particle Substances 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 238000000354 decomposition reaction Methods 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 229960004799 tryptophan Drugs 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 230000005484 gravity Effects 0.000 description 3
- 238000003505 heat denaturation Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 238000004781 supercooling Methods 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- 238000011017 operating method Methods 0.000 description 2
- 239000003507 refrigerant Substances 0.000 description 2
- 239000004278 EU approved seasoning Substances 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229910001514 alkali metal chloride Inorganic materials 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000011549 crystallization solution Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000020774 essential nutrients Nutrition 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 239000002777 nucleoside Substances 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 238000006798 ring closing metathesis reaction Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
Landscapes
- Physical Water Treatments (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11153746A JP2000334204A (ja) | 1999-06-01 | 1999-06-01 | 凍結濃縮晶析方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11153746A JP2000334204A (ja) | 1999-06-01 | 1999-06-01 | 凍結濃縮晶析方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000334204A true JP2000334204A (ja) | 2000-12-05 |
| JP2000334204A5 JP2000334204A5 (enExample) | 2005-06-09 |
Family
ID=15569218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11153746A Pending JP2000334204A (ja) | 1999-06-01 | 1999-06-01 | 凍結濃縮晶析方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2000334204A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006136811A (ja) * | 2004-11-12 | 2006-06-01 | Shin Nippon Air Technol Co Ltd | 融解分離方法及びこれを使用する融解分離装置 |
-
1999
- 1999-06-01 JP JP11153746A patent/JP2000334204A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006136811A (ja) * | 2004-11-12 | 2006-06-01 | Shin Nippon Air Technol Co Ltd | 融解分離方法及びこれを使用する融解分離装置 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20040820 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20040906 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080304 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20080701 |