JP2000302655A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To sufficiently improve the freshness of aftertaste of a composition for oral cavity. SOLUTION: This composition contains a functional substance capable of masking foreign tastes originated from compounding components and intensifying fresh feeling as an improving agent for aftertaste. The functional substance is selected from group consisting of substances having bitterness, sourness and astringency. A substance having bitterness (sourness or astringency) is a natural product having bitterness (sourness or astringency), an extract of a natural product having bitterness (sourness or astringency) and/or a compound having bitterness (sourness or astringency). A preferable mode of composition has a water content of 5 wt.% or less, and contains a heat generating body. In this case, the heat generating body is anhydrous zeolite, anhydrous magnesium sulfate, dextrin, sodium metaphosphate and/or calcium chloride.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an oral composition having an improved aftertaste.

[0002]

2. Description of the Related Art When an oral composition containing a base or the like having various off-tastes is used, even if it is gargled after use, the off-taste derived from these bases or the like remains, and after use, it is refreshed after use. There was a problem that a sense of sensation was not obtained. Japanese Patent Application Laid-Open No. Hei 8-24535 discloses a method for improving a refreshing aftertaste.
No. 0 publication, by containing at least one of 8-acetylated sucrose, quinine hydrochloride, quinine sulfate, caffeine, brucine, leaving no sweetness derived from the base,
It has also been reported that a refreshing aftertaste is provided, and that a refreshing sensation is enhanced by a pungent component. JP-A-57-
According to Japanese Patent No. 82300, a dentifrice composition that enhances a refreshing feeling without increasing the amount of menthol by adding one or more kinds of vanillyl alcohol derivatives, and gives a refreshing feeling and refreshing in the oral cavity Offering things.

[0003]

However, the refreshing feeling of the aftertaste of the oral composition has not been sufficiently improved.
Therefore, an object of the present invention is to sufficiently improve the refreshing feeling of the aftertaste of the oral composition.

[0004]

Means for Solving the Problems In order to improve the refreshing feeling of the aftertaste of the oral composition, the present inventors have proposed an active ingredient, a sweetener and an off-taste derived from an active ingredient which are usually contained in a base. It was thought that it was important to mask not only sweetness, bitterness, astringency, etc.) but also to enhance the refreshing sensation that is essential for oral compositions. Therefore, as a result of searching for a substance that satisfies these two at the same time, in an oral composition in which a functional substance selected from the group consisting of those having pungency, those having acidity, and those having astringency,
In the composition for the oral cavity, the simultaneous satisfying of two of the masking of the off-taste derived from the base and the enhancement of the refreshing sensation is further achieved.
And "enhancing the refreshing feeling" at the same time,
We have discovered for the first time that it has an effect on improving the “freshness of aftertaste”. Furthermore, the improvement in the refreshing feeling of the aftertaste can be proved to be more effective in a warm toothpaste in which the aftertaste is not refreshing as compared with a general toothpaste.

[0005] Accordingly, the gist of the present invention is an oral composition containing a functional substance that masks off-taste derived from the components and enhances a refreshing sensation as an agent for improving the refreshing feeling of aftertaste. The above-mentioned functional substance can be described as a functional substance that masks off-flavors derived from the components and enhances the refreshing sensation by improving the refreshing sensation. The above-mentioned functional substance is a substance that stimulates the oral cavity, and may be anything that enhances the refreshing sensation, and is selected from the group consisting of those having pungency, those having acidity, and those having astringency. In this case, the present invention is an oral composition containing a pungent, sour, or astringent as an agent for improving the refreshing aftertaste.

The above oral composition preferably has a water content of 5% by weight or less and has a heating element, more specifically, anhydrous zeolite, anhydrous magnesium sulfate, dextrin,
In this case, the present invention provides a functional substance which masks off-taste derived from the ingredients and enhances a refreshing sensation as an agent for improving the refreshing sensation of aftertaste, which contains sodium metaphosphate and / or calcium chloride. Contains substances selected from the group consisting of those having a pungent taste, those having a sour taste, and those having astringency, having a water content of 5% by weight or less, and a heating element, more specifically, anhydrous zeolite. An oral composition comprising anhydrous magnesium sulfate, dextrin sodium metaphosphate and / or calcium chloride.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The oral composition of the present invention comprises a "functional substance which masks off-taste derived from the ingredients and improves the refreshing feeling of aftertaste by enhancing the refreshing feeling". It can be found by searching for a substance that can be added to a substance and has both a masking function for off-taste and a function of enhancing a refreshing sensation from the blended base component. The off-taste derived from the above-mentioned components is the active agent, sweetener, and persistent sweetness, bitterness, and astringency derived from the base component, which are usually left in the oral composition after use, and remain even after gargle. Etc. means the aftertaste.

The above-mentioned functional substance may be any substance that stimulates the oral cavity and enhances the refreshing sensation, and is preferably a substance having a pungent, sour, or astringent taste. As an example. Those having pungency are pungent natural products, extracts extracted from pungent natural products, and / or pungent compounds. Examples of natural products having pungency include spices such as pepper, ginger, wasabi, pepper, mustard and the like. Examples of extracts extracted from pungent natural products and pungent compounds include piperine, isopiperine, shavicin, isosabicin, capsaicin, capsicum extract, zingerone, and vanillyl ether. Those having a sour taste are more specifically natural products having a sour taste, extracts extracted from natural products having a sour taste and / or compounds having a sour taste, more specifically citric acid, malic acid, tartaric acid , Fumaric acid, ascorbic acid and the like. Those having astringency are, more specifically, natural products having astringency, extracts extracted from natural products having astringency, and compounds having astringency, more specifically, tannic acid and lactic acid. Astringents such as aluminum and magnesium sulfate.

[0009] The content of the substance having pungency is defined as a range which can effectively exert two functions of masking the off-taste derived from the blended base ingredients and improving the refreshing sensation at the same time to improve the refreshing feeling of the aftertaste. It can be appropriately determined by experiments and the like. Usually, a compound having a pungency of 0.01 to
Contains 100 ppm. If the compound having pungency is less than 0.01 ppm as a compound having pungency, the off-taste derived from the compounded components cannot be masked. If the compound having pungency is more than 100 ppm as a compound having pungency, the oral composition itself becomes spicy and the aftertaste is not improved. The content of those having sourness is determined by sensory experiments, etc., in order to improve the refreshing feeling of aftertaste by simultaneously exerting the two functions of masking of off-taste and improving function of refreshing sensation derived from the formulated base ingredients at the same time. It can be determined appropriately. Usually, it contains 0.01 to 100 ppm as a compound having a sour taste. Those with sourness are 0.01p as compounds with sourness
When the amount is less than pm, off-flavors derived from the components cannot be masked. A compound having acidity but having an acidity of 10
If it is more than 0 ppm, the oral composition itself becomes sour and the aftertaste is not improved. The content of those with astringency is based on the range in which the masking function of off-taste derived from the formulated base component and the function of improving the refreshing sensation can be simultaneously and effectively exerted to improve the refreshing feeling of the aftertaste. Can be determined as appropriate. Usually, the compound having astringency is 0.1.
It contains from 01 to 100 ppm. If the compound having astringency is less than 0.01 ppm as a compound having astringency, the off-taste derived from the compounded components cannot be masked. When the compound having astringency but having a pungency is more than 100 ppm, the oral composition itself becomes harsh and the aftertaste is not improved.

The oral composition, especially a dentifrice, having an improved aftertaste of the present invention preferably has a water content of 5% by weight.
And a heating element is contained. When the water content is 5% by weight or less, the adsorption rate of the compounded medicinal agent in the oral cavity can be increased. By adding a heating element, a heating effect can be obtained. By the warming effect, the adsorption rate of the medicinal agent can be increased, and by the warming effect, the blood circulation of gums can be promoted, and the effect of preventing and treating periodontal disease can be enhanced.

The medicinal agent to be combined may be any as long as it is a medicinal agent incorporated into an oral composition for the purpose of preventing and treating periodontal disease. Examples of the blood circulation promoter include vitamin E, dl-α-tocopherol nicotinate, sodium chloride and the like; examples of the anti-inflammatory agent include allantoin;
β-glycyrrhetinic acid, glycyrrhizic acid, epidihydrocholesterin, dihydrocholesterol, ε-aminocaproic acid, hinokitiol, lysozyme chloride and the like; fungicides such as benzetium chloride, chlorhexidine hydrochloride, triclosan, cetylpyridium chloride, isopropyl chloride Methyl phenol, decalinium chloride, alkyl diaminoethyl glycine hydrochloride and the like can be mentioned. One or more of these medicinal agents can be used,
0.1 to 5% by weight, especially 0.01 to 1% by weight in the total composition
It is preferable to mix them. By increasing the adsorption rate of the medicinal agent into the oral cavity, it is possible to enhance the effect of preventing and treating periodontal disease.

The heating element is preferably used so as to have an exothermic temperature of 38 to 50 ° C., particularly 40 to 45 ° C. Specifically, anhydrous zeolite, anhydrous magnesium sulfate, sodium metaphosphate, calcium chloride, dextrin, etc. Is mentioned. One or more heating elements can be used, and it is preferable to add 0 to 5% by weight, particularly 20 to 30% by weight in the total composition.

The above-mentioned oral composition may contain glycerin, propylene glycol, polyethylene glycol, triglyceride, diglyceride, liquid paraffin and the like as a liquid vehicle. These liquid vehicles are:
One or more kinds can be used, and it is preferable to mix 30 to 80% by weight, particularly 40 to 60% by weight in the total composition. In addition, the viscosity can be adjusted by adding a thickener to the above oral composition, and when a heating element is added, the heat generation temperature can be adjusted. Examples of the thickener include xanthan gum, silica (silicic anhydride), dextrin, carrageenan, hydroxypropyl cellulose, and hydroxyethyl cellulose. Among these, xanthan gum is most preferred in the embodiment having a water content of 5% by weight.
With such a thickener, the viscosity of the composition at 25 ° C is 3000 to 15000 dPa · s, particularly 4000 to 100 dPa · s.
It is preferably prepared so as to be 00 dPa · s.

[0014] The oral composition of the present invention may further contain components usually used in the oral composition, for example, surfactants, abrasives, sweeteners, flavors, preservatives, whitening agents, wetting agents, binders and the like. Can be appropriately compounded within a range that does not impair the effects of the present invention.

The oral composition of the present invention can be formulated by a usual method. In the case of a dentifrice, the form may be any of powder, paste, and solution. In the case of a toothpaste, the desired paste can be obtained by mixing and stirring the components and then degassing. It can be applied intraorally by the usual methods.

[0016]

The refreshing taste of the aftertaste of the oral composition is enhanced by the masking of the off-flavor derived from the formulated base component and the enhancement of the refreshing feeling.
The improvement can be achieved by adding a functional base which satisfies both conditions at the same time, more specifically, a base having a pungent taste, a base having a sour taste, or a base having astringency. In addition, the improvement of the aftertaste of the aftertaste by adding a functional substance is intended for preventing and treating periodontal disease, for oral compositions containing various medicinal agents, particularly for oral mucosa of the combination. By increasing the adsorption rate of the compound, there is a remarkable effect in an oral composition having an excellent effect of preventing and treating periodontal disease.

[0017]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described in detail with reference to embodiments.

Example 1 A toothpaste having the composition shown in Table 1 was prepared. Using this dentifrice, toothpaste was performed according to a conventional method, and (1) an unpleasant muskin ゛, (2) a refreshing sensation of aftertaste, and (3) an effect of improving aftertaste were evaluated. Table 2 shows the results.

[0019]

[Table 1] ──────────────────────── Component usage (% by weight) ──────────────カ ル シ ウ ム Calcium carbonate 35.00 sorbitol 25.00 Saccharin sodium 0.10 Propylene glycol 5.00 Carboxymethylcellulose 1.00 Carrageenan 1.00 Methyl parahydroxybenzoate 0.10 Sodium lauryl sulfate 1.50 Flavor 1.00 Pungent, astringent, and sour (see Table 2) Purified water Balance ────────────────────────

[0020]

[Table 2] も の Those with pungent, sour and astringent taste No masquenque ゛ Refreshing aftertaste Aftertaste evaluation (ppm) な し None 0 × △ × Piperine 10 ◎ ◎ ◎ Capsaicin 10 ◎ ◎ 〇 Capsicum oleoresin 10 〇 〇 〇 Vanillyl butyl ether 10 〇 〇 ク エ ン Citric acid 10 ◎ ◎ リ ン ゴ Malic acid 10 ◎ 〇 ◎ Tartaric acid 10 △ ◎ 〇 Ascorbic acid 10 〇 〇 〇 Acid 10 △ 〇 〇 Tannic acid 10 ◎ ◎ ◎ Aluminum lactate 10 〇 〇 マ グ ネ シ ウ ム Magnesium sulfate 10 〇 〇 〇 ─────────────────────────── ───────

The evaluation criteria in Table 2 are as follows. [Maskink of off-flavors ゛ Evaluation criteria] ：: No off-flavors at all ほ と ん ど: Almost no off-flavors Δ: Off-flavors ×: Off-flavors are quite persistent [Evaluation criteria for refreshing sensation of aftertaste] ：: Refreshing sensation very strong 〇: Refreshing Slightly strong △: Refreshing feeling slightly weak ×: Refreshing feeling weak [Aftertaste evaluation criteria] ◎: Aftertaste is very refreshing 〇: Aftertaste is refreshing △: Aftertaste is not refreshing ×: Aftertaste is not refreshing

As is clear from Table 2, toothpaste can be obtained by mixing piperine, capsaicin, capsicum oleoresin, vanillyl butyl ether, citric acid, malic acid, tartaric acid, fumaric acid, tannic acid, aluminum lactate and magnesium sulfate. It can be seen that the masking of unpleasant taste, the refreshing sensation of the aftertaste, and the effect of improving the aftertaste are improved, especially when piperine is added.

Example 2 A toothpaste having a composition shown in Table 3, containing a medicinal agent, having a water content of 5% by weight or less, and containing a heating element was prepared. Brush your teeth using this dentifrice in the usual way,
(1) Unpleasant muskin ゛, (2) cool feeling of aftertaste, and (3) effect of improving aftertaste were evaluated. Table 4 shows the results.

[0024]

[Table 3] ───────────────────────── Component usage (% by weight) ───────────── Dl dl-α-tocopherol acetate 0.10 benzethonium chloride 0.01 β-glycyrrhetinic acid 0.01 concentrated glycerin 28.00 propylene glycol balance saccharin sodium 0.20 xanthan gum 0.50 anhydrous Silicic acid 10.00 Calcium hydrogen phosphate 10.00 Anhydrous zeolite 20.00 Sodium lauryl sulfate 1.00 Fragrance 1.00 Pungent, sour and astringent (described in Table 4) ─────────────────

[0025]

[Table 4] も の Those with pungent, sour and astringent taste Unpleasant muskin ゛ Refreshing aftertaste Aftertaste evaluation (ppm) な し None 0 × △ × Piperine 10 ◎ ◎ ◎ Capsaicin 10 〇 ◎ 〇 Capsicum oleoresin 10 ◎ 〇 〇 Vanillyl butyl ether 10 〇 〇 〇 Citric acid 10 ◎ ◎ リ ン ゴ Malic acid 10 〇 ◎ ◎ Tartaric acid 10 〇 〇 ア ス Ascorbic acid 10 〇 〇 Fumaric acid 10 〇 〇 Tannic acid 10 ◎ ◎ ア ル ミ ニ ウ ム Aluminum lactate 10 〇 〇 マ グ ネ シ ウ ム Magnesium sulfate 10 ◎ ◎ ◎ ─────────────────────────評 価 The evaluation criteria in Table 4 are the same as in Table 2.

As is apparent from Table 4, when piperine, capsaicin, capsicum oleoresin, vanillyl butyl ether, citric acid, malic acid, tartaric acid, fumaric acid, tannic acid, aluminum lactate, and magnesium sulfate are added, a medicinal agent is obtained. In a toothpaste containing 5% by weight or less of water and containing a heating element, the masking of the off-taste, the refreshing feeling of the after-taste, and the effect of improving the after-taste are improved, especially with piperine or sulfuric acid. It can be seen that the addition of magnesium significantly improves the performance.

Example 3 A mouthwash having the composition shown in Table 5 was prepared. The mouth washes were performed using the mouthwash according to a conventional method, and (1) off-flavored musqueine, (2)
The refreshing feeling of the aftertaste and (3) the effect of improving the aftertaste were evaluated. Table 6 shows the results.

[0028]

[Table 5] ──────────────────────────── Component usage (% by weight) ──────────エ タ ノ ー ル Ethanol 15.00 Glycerin 10.00 Saccharin sodium 0.20 Licorice extract 0.10 Polyoxyethylene hydrogenated castor oil 1.00 Methyl benzoate 0.10 Sodium paraoxybenzoate 0.10 Sodium dihydrogen phosphate 0.10 Fragrance 0.50 Colorant Appropriate amount Pungent, sour, astringent (described in Table 6) Purified water Balance ────────── ──────────────────

[0029]

[Table 6] も の Those with pungent, sour and astringent taste No masquenque ゛ Refreshing taste of aftertaste (ppm) な し None 0 × △ × Piperine 5 ◎ ◎ ◎ Capsaicin 5 ◎ ◎ ◎ Capsicum oleoresin 5 ◎ 〇 〇 Vanillyl butyl ether 5 〇 〇 ク エ ン Citric acid 10 ◎ ◎ Malic acid 10 〇 〇 ◎ Tartaric acid 10 〇 ◎ ア ス Ascorbic acid 10 〇 〇 Acid 10 〇 〇 〇 Tannic acid 5 〇 〇 ア ル ミ ニ ウ ム Aluminum lactate 5 〇 〇 マ グ ネ シ ウ ム Magnesium sulfate 5 ◎ ◎ ◎ ───────────────────────────評 価 The evaluation criteria in Table 6 are the same as in Table 2.

As is apparent from Table 6, when piperine, capsaicin, capsicum oleoresin, vanillyl butyl ether, citric acid, malic acid, tartaric acid, fumaric acid, tannic acid, aluminum lactate, and magnesium sulfate were mixed, It can be seen that the improvement of the unpleasant taste of the skin, the refreshing sensation of the aftertaste, and the effect of improving the aftertaste are remarkably improved, especially when piperine, capsaicin citric acid or magnesium sulfate is added.

[0031]

According to the present invention, the aftertaste of the oral composition is improved, and a very refreshing and good aftertaste can be provided.

Continued on the front page F term (reference) 4C083 AA112 AB012 AB051 AB222 AB272 AB282 AB292 AB322 AB342 AB361 AB362 AB441 AB442 AC102 AC122 AC132 AC172 AC292 AC302 AC432 AC472 AC482 AC642 AC692 AC782 AC842 AC852 AC862 AD241 AD272 AD352 AD392 AD532 AD662 BB55 CC41EE22 DD23 DD23 DD23 EE31

Claims (7)

[Claims] Claims: 1. An oral composition containing a functional substance which masks off-taste derived from a compound component and enhances a refreshing sensation as an agent for improving a refreshing aftertaste. 2. The oral composition according to claim 1, wherein the functional substance is selected from the group consisting of those having a pungent taste, those having a sour taste, and those having astringency. 3. The pungent substance is a pungent natural product, an extract extracted from the pungent natural product, and / or
3. The oral composition according to claim 2, which is a compound having pungency. 4. A sour-tasting natural product having a sour taste, an extract extracted from a sour natural product, and / or
3. The oral composition according to claim 2, which is a compound having an acidity. 5. A substance having astringency is a natural product having astringency, an extract extracted from a natural product having astringency, and / or
3. The oral composition according to claim 2, which is a compound having astringency. 6. The oral composition according to claim 2, which has a water content of 5% by weight or less and contains a heating element. 7. The oral composition according to claim 6, wherein the heating element is anhydrous zeolite, anhydrous magnesium sulfate, dextrin, sodium metaphosphate and / or calcium chloride.