CN107205900A

CN107205900A - Dentrifice composition

Info

Publication number: CN107205900A
Application number: CN201680007255.8A
Authority: CN
Inventors: 深泽哲
Original assignee: Lion Corp
Current assignee: Lion Corp
Priority date: 2015-01-26
Filing date: 2016-01-22
Publication date: 2017-09-26
Also published as: KR20170104996A; JP2016138047A; WO2016121650A1

Abstract

A kind of Dentrifice composition is provided, the Dentrifice composition contains the mass % of (A) aluctyl 0.01~5, the mass % of (B) condensed phosphate 0.01~5, the mass % of (C) alhpa olefin sulfonate 0.1~3, it suppresses the excellent effect of pH reductions while playing high dentinal tubule sealing effect, pH reductions over time are inhibited, in addition metallic taste is inhibited, use feeling is also good, is suitable for use as suppressing hyperesthesia use；And, a kind of method that pH reductions suppressed in Dentrifice composition and metallic taste are presented is provided, methods described is the mass % of (B) composition 0.01~5 described in addition and the mass % of (C) composition 0.1~3 in the Dentrifice composition containing the mass % of (A) composition 0.01~5.

Description

Dentrifice composition

Technical field

The present invention relates to suppress the excellent effect of pH reductions while playing high dentinal tubule sealing effect, pushed away with the time The pH reductions of shifting are inhibited, and metallic taste is inhibited in addition and use feeling is also good, be suitable for suppressing hyperesthesia Dentrifice composition containing aluctyl.

Background technology

There is aluctyl constriction to block the effect of dentinal tubule, although prevention for dentine acroesthesia is controlled Treat effective, but aluctyl is added in composition for oral cavity, then pH reductions over time can be produced, due to deviation In acid and cause tooth demineralization or oral mucosa to be peeled off etc., the problem of with bad stability, in addition, it is special also to have generation aluminium The problem of some metallic tastes.

For it is such the problem of, in patent document 1 (Japanese Patent Laid-Open 10-231237 publications), it is proposed that pass through Sugar alcohol is added in the liquid oral composition containing aluctyl, gonorrhoea is prevented, precipitate and improve the technical scheme of stability, In patent document 2 (Japanese Patent Laid-Open 2013-119520 publications), it is proposed that by containing potassium nitrate and/or aluctyl Dentrifice composition in addition anionic surfactant, specific water-soluble high-molecular substance, propylene glycol alginate, Ensuring sufficiently frothed while improving the technical scheme of storage stability (liquid segregational stability), but these patent documents do not have Refer to that pH over time changes.

On the other hand, it is known that condensed phosphate can be added together with aluctyl in composition for oral cavity, patent text Offer in 3 (Japanese Patent Laid-Open 7-165550 publications), used as the oral cavity of effective prevention, treatment dentine acroesthesia Composition, describes the band (embodiment 7) of the oral cavity containing aluctyl and sodium pyrophosphate.(the Japanese Patent Laid-Open of patent document 4 2002-302429 publications) in, it is proposed that, addition is used as acid with non-water system composition for oral cavity base material and sodium bicarbonate together The aluctyl of property composition, improves bitter taste and the scheme of pungent non-water system composition for oral cavity, is further used as addible Anti-tartar deposits the illustration of composition, describes sodium pyrophosphate, polyphosphate sodium.(the Japanese Patent Laid-Open 2004-26816 of patent document 5 Number publication) in, aluctyl, sodium pyrophosphate, polyphosphate sodium etc. can be added in solid formulation composition for oral cavity by disclosing.

Prior art literature

Patent document

Patent document 1：Japanese Patent Laid-Open 10-231237 publications

Patent document 2：Japanese Patent Laid-Open 2013-119520 publications

Patent document 3：Japanese Patent Laid-Open 7-165550 publications

Patent document 4：Japanese Patent Laid-Open 2002-302429 publications

Patent document 5：Japanese Patent Laid-Open 2004-26816 publications

The content of the invention

Invent problem to be solved

But, for suppress the composition for oral cavity containing aluctyl pH reduce, it is hard to say be it is sufficient, also have can improve Leeway, expect develop it is a kind of can more effectively suppress pH reduction technology.

The present invention is obtained in view of the above fact, and its object is to provide a kind of the same of high dentinal tubule sealing effect of performance When suppress pH reduction excellent effect, over time pH reduction be inhibited, metallic taste is inhibited and use feeling in addition Also the good Dentrifice composition containing aluctyl.

The means to solve the problem

In order to reach above-mentioned purpose, the present inventor has found after being concentrated on studies, by containing (A) aluctyl 0.01~ The mass % of (B) condensed phosphate 0.01~5 and (C) alpha-alkene sulfonate 0.1~3 are added in 5 mass % Dentrifice composition Quality %, suppresses the excellent effect of pH reductions, pH drops over time while obtaining high dentinal tubule sealing effect Low to be inhibited, metallic taste is inhibited in addition and use feeling is also improved, and is applicable to suppress hyperesthesia, and then complete The present invention.

Shown in comparative example i.e., as be described hereinafter, the Dentrifice composition containing aluctyl, if without pyrophosphate and alpha-olefin If sulfonate, even if containing anionic surfactant's NaLS, over time, can still occur pH reductions, PH changes, and metallic taste, taste deterioration (comparative example 7), even if in addition, added with pyrophosphate and alpha-olefin sulfonic acid is presented Salt, if if the amount of any one party is improper, pH can still be reduced, or is presented metallic taste or oil sense, use feeling variation (comparative example 3 ~6).On the other hand, shown in embodiment as be described hereinafter, if by (A) aluctyl and (B) condensed phosphate, (C) alpha-alkene sulfonate If being added in combination Dentrifice composition with appropriate amount, the combination of (B), (C) composition has special effect, the tooth that aluctyl is brought While tubules sealing effect is excellent, pH variable quantities have not also been played in the case of being preserved 1 month at even 50 DEG C also not The effect of excellent the suppressions pH reductions of foot 1.0, pH tending towards stability over time, can prevent deviation acidity, in addition, going back Metallic taste can be suppressed, prevent that oily sense is presented, delicious good use feeling can be assigned.

In addition, now, if if (B) component amount is excessive, the metallic taste from (A) composition is more strongly presented, if in addition, (C) if component amount is excessive, the problem of oil sense becomes strong can be produced, by the way that (B), (C) composition are combined as, can eliminate complete These problems of portion, assign above-mentioned excellent action effect.

Therefore, the pH that the present invention is provided in following Dentrifice compositions and suppression Dentrifice composition is reduced and metallic taste is in Existing method.

(1) a kind of Dentrifice composition, it is characterised in that contain the mass % of (A) aluctyl 0.01~5, (B) condensed phosphate 0.01~5 mass %, the mass % of (C) alpha-alkene sulfonate 0.1~3.

(2) Dentrifice composition according to (1), it is characterised in that the condensed phosphate of (B) composition is pyrophosphate or three Quadrafos.

(3) Dentrifice composition according to (1) or (2), it is characterised in that (C) alpha-alkene sulfonate is carbon number 14 ~16 alpha-alkene sulfonate.

(4) according to the Dentrifice composition any one of (1)~(3), it is characterised in that (B)/(A) be by quality ratio 0.005~50, and (C)/(A) is 0.05~100 by quality ratio.

(5) Dentrifice composition according to any one of (1)~(4), it is characterised in that also containing (D) potassium nitrate 0.1~ 7 mass %.

(6) Dentrifice composition according to any one of (1)~(5), it is characterised in that the pH at 25 DEG C is more than 5.

(7) Dentrifice composition according to any one of (1)~(6), it is characterised in that be modulated to toothpaste.

(8) a kind of method that pH reductions suppressed in Dentrifice composition and metallic taste are presented, it is characterised in that containing (A) In the mass % of aluctyl 0.01~5 Dentrifice composition, the addition mass % of (B) condensed phosphate 0.01~5 and (C) alpha-olefin The mass % of sulfonate 0.1~3.

(9) according to (8) method that the pH reductions suppressed in Dentrifice composition and metallic taste is presented, it is characterised in that (B)/(A) is 0.005~50 by quality ratio, and (C)/(A) is 0.05~100 by quality ratio.

(10) according to (8) or (9) method that the pH reductions suppressed in Dentrifice composition and metallic taste is presented, its feature It is, the mass % of (D) potassium nitrate 0.1~7 is added also in Dentrifice composition.

(11) according to any one of (8)~(10) side that the pH reductions suppressed in Dentrifice composition and metallic taste is presented Method, it is characterised in that pH of the Dentrifice composition at 25 DEG C is more than 5.

(12) according to any one of (8)~(11) side that the pH reductions suppressed in Dentrifice composition and metallic taste is presented Method, it is characterised in that be modulated to toothpaste.

Invention effect

According to the present invention it is possible to suppress the effect of pH reductions while providing a kind of performance high dentinal tubule sealing effect PH reductions excellent, over time are inhibited, and metallic taste is inhibited in addition, oil sense is also inhibited and assigned well Use feeling, the Dentrifice composition containing aluctyl for being suitable for suppressing hyperesthesia.

Embodiment

Hereinafter, the present invention will be described in more detail.The Dentrifice composition of the present invention contains (A) aluctyl, (B) contracting Quadrafos, (C) alpha-alkene sulfonate.

(A) aluctyl is the reaction product of lactic acid and metallic aluminium, and chemical formula is expressed as C₉H₁₅AlO₉, it is white and tasteless Powder.It is used as the effect for tooth, it is known to make the dentinal tubule sealing effect of dentinal tubule constriction or blocking, has There is the effect for exposing produced dentine acroesthesia mitigated by dentinal tubule.Aluctyl can use commercially available product.

As the addition of the aluctyl of (A) composition be total composition 0.01~5% (quality %, it is same as below.), preferably For 0.1~3%, more preferably 1~2%.If if addition more than 0.01%, enough dentinal tubule closing effects can be assigned Really.Do not add excessively to fully suppressing pH reductions, improving use feeling favorably, if more than 5%, pH reductions tendency becomes very By force, metallic taste is presented strongly in addition.

In the present invention, by the way that (B) condensed phosphate is added in the lump with (C) alpha-alkene sulfonate, high dentine is played small Excellent suppression pH reducing effects are assigned while duct occlusion effect, also improve use feeling.If if (B) composition is not enough, it is impossible to Suppress pH reduction, if if (C) composition is not enough, it is impossible to suppress metallic taste, use feeling is poor.

As (B) condensed phosphate, following formulas (1) or straight-chain or the polycondensation phosphorus of ring-type shown in (2) can be used Hydrochlorate.

M_n+2P_nO_3n+1 (1)

(MPO₃)_m (2)

(in formula, M represents that Na or K, n are more than 2 integers, and m is more than 3 integer.)

As the straight-chain Quadrafos shown in above-mentioned formula (1), n=2 sodium pyrophosphate or potassium pyrophosphate, n=3 can be enumerated Sodium tripolyphosphate or PTPP, n=4 sodium tetrapolyphosphate or four PA 800Ks, the sodium metaphosphate of high polymerization degree or inclined phosphorus Sour potassium etc..

As the cyclic polyphosphates shown in above-mentioned formula (2), m=3 sodium trimetaphosphate or three potassium metaphosphates, m=4 can be enumerated Four sodium metaphosphates or four potassium metaphosphates, m=6 calgon or hexa metaphosphoric acid potassium etc..

These condensed phosphates individually one kind or two or more can be used in mixed way, wherein, the preferred water-soluble polycondensation phosphorus of straight-chain Hydrochlorate, especially pyrophosphate, tripolyphosphate, especially more preferably pyrophosphate, further preferred sodium salt.

Specifically, commercially available product can be used, for example, can use sodium pyrophosphate (peaceful Chemical Industries (strain) manufacture, northeast chemistry (strain) is manufactured), potassium pyrophosphate (manufacture of peaceful Chemical Industries (strain), East Asia synthesis chemical (strain) manufacture), sodium tripolyphosphate it is (peaceful Chemical Industries (strain) manufacture, Japan glass (strain) (Central Glass Co., Ltd.) manufacture, Nihon builder Co., Ltd. (Japanese PVC ルダー (strain)) is manufactured) etc..

(B) addition of the condensed phosphate of composition is the 0.01~5% of total composition, preferably 0.1~1%, more excellent Select 0.3~0.5%.Addition can assign the gratifying effect for suppressing pH reductions more than 0.01%, then.But Many additions are favourable to improving use feeling, if more than 5%, metallic taste is presented strongly, use feeling reduction.

As (C) alpha-alkene sulfonate, sodium salt, sylvite of alpha-olefin sulfonic acid that carbon number is 14~16 etc. can be used The alpha-alkene sulfonate of alkali metal salt, preferably carbon number 14, particularly sodium salt (common name：Tetradecene sodium sulfonate).

These alpha-alkene sulfonates can use commercially available product.Specifically, tetradecene sodium sulfonate (alpha-olefin (C14) can be used Sodium sulfonate, lion king special chemical (strain) system, " K LIPOLAN PJ-400CJ ") etc..

In addition, alpha-alkene sulfonate has as accessory substance containing hydroxy alkyl sulfonic acid salt sometimes, its ratio is not limited especially It is fixed, but generally below 20%, such alpha-alkene sulfonate can be used in the present invention.

(C) addition of the alpha-alkene sulfonate of composition is the 0.1~3% of total composition, preferably 0.5~2%, more Preferably 0.7~1.5%.If in the range of the above-mentioned addition, use feeling can be improved.If addition is not enough If 0.1%, then it can not suppress metallic taste, if more than 3%, strong oil feel is strong to be presented, and taste deterioration, use feeling is poor.

In addition, even by the alkyl sulfates such as the NaLS of anionic surfactant and (B) polycondensation phosphorus Hydrochlorate is added in the lump, can not also improve the reduction for the use feeling brought by (A) aluctyl, it is impossible to reach the purpose of the present invention.

In the present invention, if if (A) composition is combined in appropriate proportions with (B) composition, (C) composition, can further carry Height suppresses the effect of pH reductions, can also further improve use feeling.

Now, represent (B) composition addition relative to (A) composition addition (B)/(A) by quality ratio, can for 0.005~ 50, preferably 0.005~5, more preferably 0.1~3.In addition, representing (C) composition addition relative to (A) composition addition (C)/(A) can be 0.05~100, preferably 0.05~3, more preferably 0.3~1 by quality ratio.

(B)/(A) and/or (C)/(A) are in above-mentioned ratio ranges, and effect of the invention is more excellent.

Further, in the present invention, (D) potassium nitrate can be added.Potassium nitrate can relax the pain that hyperesthesia is brought, as It is effective that hyperesthesia suppresses composition.

(D) addition of the potassium nitrate of composition is preferably the 0.1~7% of total composition, more preferably 0.5~5%.If at this In the range of add if, contribute to strengthen hyperesthesia inhibition.In addition, it helps the effect of suppression pH reductions of the invention Really, suppress metallic taste to present.

It is preferred that pH of the Dentrifice composition of the present invention at 25 DEG C is located at into more than 5, particularly 5~10, more preferably set For 6~8, such pH is preferably regulated as.If pH is more than 5, dentinal tubule sealing effect can be given full play to, is also had Help use.

In addition, during adjustment pH, pH regulators can be added, the hydroxide of alkali metal, carbonic acid such as can add sodium hydroxide Hydrogen salt, carbonate etc..

The Dentrifice composition of the present invention is adapted to be modulated to toothpaste, liquid dentifrice, moistening dentifrice etc., is especially suitable for adjusting It is made as toothpaste.In addition, in addition to mentioned component, in the range of without prejudice to effect of the present invention, can also be added as needed on Other known compositions.For example, in toothpaste, grinding agent, binding agent, thickener, further surfactant, basis can be added Sweetener, colouring agent, preservative, spices, active ingredient for needing etc..Furthermore it is possible to water be added as liquid media, with usual Method be modulated.

As grinding agent, the silica such as precipitated silica, aluminosilicate, zirconium silicate based abrasive, phosphorus can be enumerated Sour calcium based compound, calcium carbonate, aluminium hydroxide, synthetic resin based abrasive etc..Generally, the addition of grinding agent, in toothpaste It is 0~30% in liquid dentifrice for 10~50%.

As binding agent, the glue such as carrageenan (carrageenan), xanthans (xanthan gum) can be enumerated (gum) organic binder bond such as cellulose derivative such as class, sodium carboxy methyl cellulose, gelation silica, gelation The inorganic binders such as aluminium silica.The addition of binding agent is typically 0.1~10%, is preferably 0.1~5% in toothpaste, It is 0~5% in liquid dentifrice.

As thickener, the sugar alcohols such as D-sorbite, xylitol, propane diols, polyalcohol can be enumerated.The addition of thickener leads to It is often 5~50%, particularly preferred 20~45%.

As surfactant, anionic surfactant, nonionic surfactant, cationic can be added Surfactant, amphoteric surfactant.

As anionic surfactant, alkyl sulfates such as NaLS etc. can be enumerated.It is used as non-ionic surface Activating agent, the average addition molal quantity that can enumerate oxirane is the polyoxyethylene fat such as 5~60 Crodaret Fat acid esters, sugar fatty acid ester, sugar alcohol fatty acid ester, polyglyceryl fatty acid ester, polyoxyethylene higher alcohol ether etc..

As cationic surfactant, alkyl ammonium type etc. can be enumerated；As amphoteric surfactant, glycine betaine can be enumerated Type, imidazoline type.

The addition of surfactant can be adjusted according to form, application target etc., such as be 0~10% in toothpaste, liquid It is 0~5% in shape dentifrice.

As sweetener, saccharin sodium etc. can be enumerated；As colouring agent, blueness 1, yellow 4, titanium dioxide can be enumerated Deng.As preservative, methyl p-hydroxybenzoate (methylparaben), ethyl-para-hydroxybenzoate etc. can be enumerated to hydroxyl Benzoic ether, benzoic acid or its salt etc..

As spices, it can be applied in combination：Fructus Piperis peppermint oil (peppermint oil), spearmint oil (spearmint Oil), fennel oil, eucalyptus oil, wintergreen, cinnamon oil (cassia oil), caryophyllus oil, thyme linaloe oil, sage oil, lemon oil (lemon oil), orange oil, peppermint oil (Ha ッカ oil), cardamom oil, coriander oil, mandarin oil (mandarin oil), limette Oily (lime oil), lavender oil, rosemary oil, oreodaphene (laurel oil), chamomile oil (chamomile oil), page Caraway oil (caraway oil), marjoram oil (marjoram oil), laurel (bay oil), lemongrass oil, origanum oil (origanum oil), pinke needle oil, bitter orange flower oil (neroli oil), attar of rose, jasmine oil, grapefruit oil (grapefruit Oil), sweetie oil, grape-fruit seed oil, concrete of iris (concrete of iris), peppermint absolute oil (absolute Peppermint), the natural perfume material such as rose absolute (absolute rose), flores aurantii；Or the working process of these natural perfume materials Spices after (front-end volatiles cutting, tails cutting, fractionation, liquid-liquid extraction, refinedization, powder perfume etc.)；And menthol, Carvol, anethole, cineole, gaultherolin, cinnamic acid, eugenol, 3-l- menthoxypropane -1,2- glycol, hundred In in phenol, linalool, acetic acid which (alcohol) Zhi, limonenes (limonene), menthones, menthyl acetate, N- substitutions-to terpane- 3- formamides, firpene, octanal, citral, pulegone, carbitol acetate, anisaldehyde, ethyl acetate, ethyl butyrate, alkene Propyl cyclohexane propionic ester, (neighbour) Methyl anthranilate, methyl phenyl ethyl glycidate, vanillic aldehyde, in hendecanoic acid Ester, hexanal, butanol, isoamyl alcohol, hexenol, dimethylsulphide, methyl cyclopentenyl ketone (cyclotene), furfural, trimethyl The monomer perfumes such as pyrazine, ethyl lactate, ethyl thioacetate；Further strawberry flavor, apple spice, banana spices, pineapple are fragrant Mediation spices such as material, grape flavor, mango spices, cream spices, milk spices, fruit potpourri, tropical fruit (tree) spices etc., The known spices raw material used in composition for oral cavity, it is not limited to the spices described in embodiment.

In addition, addition is not particularly limited, above-mentioned spices raw material preferably use 0.000001~1% in preparation composition. As the tax perfume (or spice) spices for having used above-mentioned spices raw material, preferably 0.1~2% is used in preparation composition.

As active ingredient, the known thing generally added in Dentrifice composition, such as bactericide, anti-inflammatory can be added Agent, enzyme, fluoride, plant extracts, antitartar agents, anticalculus agents etc..For example, the nonionics such as isopropyl methyl phenol can be enumerated Antiinflammatory, the glucans such as bactericide, cationic germicide, tranexamic acid (tranexamic acid), ε-aminocaproic acid, allantoin Fluorides such as the enzymes such as enzyme, sodium fluoride, sodium monofluorophosphate etc..In addition, above-mentioned active ingredient can be in without prejudice to effect of the present invention In the range of added with effective dose.

Embodiment

Embodiment and comparative example, prescription example are exemplified below, the present invention is specifically described, but the present invention is not limited to down The embodiment stated.In addition, in following examples, % unless otherwise noted, represents quality %.

[embodiment, comparative example]

The Dentrifice composition (toothpaste) of composition shown in table 1~3 is modulated by well-established law, is evaluated with following methods.As a result one And remember in table 1~3.

In addition, pH of the Dentrifice composition at 25 DEG C is adjusted into 7.0.

＜ evaluation methods ＞

(1) evaluation method of dentinal tubule sealing effect

Method (J.Dent.Res.57,187-193,1987) based on Pashley etc., to the liquid permeability of dentinal tubule Measured, evaluate the degree of closure of the dentinal tubule brought by each Dentrifice composition.

Dentine block is cut from the root of the tooth of people, is ground with water-fast pouncing paper #2000 and is made as standard specimen, be used as sample.Will 3g Dentrifice compositions are with containing the CaCl equivalent to 1mM₂And the KH equivalent to 3mM₂PO₄PH7.0 artificial saliva 6g mix Close, make 3 times of dilutions, be centrifuged, regard thus obtained supernatant liquor as disposal liquid.In addition, 3 times of dilutions are bases Dentrifice composition is by the situation of saliva dilution when it is assumed that brushing teeth.Sample is immersed in the disposal liquid 1 minute, it is clear with distilled water After washing, impregnated 12 hours in above-mentioned artificial saliva at 37 DEG C.2 same operations are carried out within 1 day, this series of operation adds up to Repeat 5 days.Last day is fully cleaned up sample with distilled water, after drying, sample is fixed, under 1 atmospheric pressure Circulated normal saline solution, and the amount of the normal saline solution of sample is passed through in the analytical unit time, is calculated and is disposed relative to disposal liquid The permeability inhibiting rate (following formula) of preceding throughput.Evaluation is carried out with n=3, using its average value.

Permeability inhibiting rate (%)=((the liquid throughput after liquid throughput-disposal before disposal)/(liquid before disposal Throughput)) × 100

Throughput：The physiological saline water (μ L) passed through in 10 minutes

From the average value of the permeability inhibiting rate obtained, the journey that dentinal tubule is closed is judged by following metewands Degree, is evaluated dentinal tubule sealing effect.

The metewand of dentinal tubule sealing effect：

◎：Permeability inhibiting rate is more than 90%

○：Permeability inhibiting rate is 80% less than 90%

△：Permeability inhibiting rate is 60% less than 80%

×：Permeability inhibiting rate is less than 60%

(2) evaluation method of the effect of pH reductions is suppressed

PH after the just manufacture of measured in advance Dentrifice composition is good at 25 DEG C, laminated tube is filled into by 50g Dentrifice compositions In (laminate tube), the pH (value at 25 DEG C) after being preserved 1 month at 50 DEG C is determined.

PH variable quantities are calculated from following formula, judge to suppress the effect of pH reductions based on following metewands.

PH variable quantities=(pH of the Dentrifice composition just the modulated)-(Dentrifice composition after being preserved 1 month at 50 DEG C pH)

Suppress the metewand of the effect of pH reductions：

◎：PH variable quantities are less than 0.5

○：PH variable quantities are 0.5 less than 1.0

△：PH variable quantities are 1.0 less than 1.5

×：PH variable quantities are more than 1.5

(3) evaluation method of use feeling

(3-1) is without metallic taste

Dentrifice composition about 1g is taken with toothbrush, is judged by the people of subject 10 based on following scoring benchmark after brushing teeth 3 minutes Metallic taste.

Scoring benchmark without metallic taste：

5 points：It is completely imperceptible

4 points：Somewhat feel

3 points：Feel

2 points：Feel strongly

1 point：Strongly feel

The average value of 10 people is tried to achieve, is judged by following metewands without metallic taste.

Metewand without metallic taste；

◎：The average mark of 10 people is more than 4.0 points

○：The average mark of 10 people is at 3.0 points less than 4.0 points

△：The average mark of 10 people is at 2.0 points less than 3.0 points

×：The average mark of 10 people is less than 2.0 points

(3-2) oil-free sense

Dentrifice composition about 1g is taken with toothbrush, is judged by the people of subject 10 based on following scoring benchmark after brushing teeth 3 minutes Oil sense.

The scoring benchmark of oil-free sense：

5 points：It is completely imperceptible

4 points：Somewhat feel

3 points：Feel

2 points：Feel strongly

1 point：Strongly feel

The average value of 10 people is tried to achieve, oil-free sense is judged based on following metewands.

The metewand of oil-free sense；

◎：The average mark of 10 people is more than 4.0 points

○：The average mark of 10 people is at 3.0 points less than 4.0 points

△：The average mark of 10 people is at 2.0 points less than 3.0 points

×：The average mark of 10 people is less than 2.0 points

Shown in being described below and state in detail of raw material.

(A) aluctyl；Manufactured by the chemical research of (strain) Musashi open country

(B) sodium pyrophosphate；Peaceful Chemical Industries (strain) manufacture

(B) sodium tripolyphosphate；Peaceful Chemical Industries (strain) manufacture

(C) alpha-olefin sodium sulfonate；Lion king special chemical (strain) is manufactured

(D) potassium nitrate；Great mound chemistry (strain) manufacture

[table 1]

[table 2]

[table 3]

Formulation Example shown below.In addition, preparation pH 25 DEG C at scope 5~10 same as described above using raw material It is interior.

[prescription example 1] dentifrice

[prescription example 2] dentifrice

Claims

1. a kind of Dentrifice composition, it is characterised in that contain the mass % of (A) aluctyl 0.01~5, (B) condensed phosphate 0.01~5 mass %, the mass % of (C) alpha-alkene sulfonate 0.1~3.

2. Dentrifice composition according to claim 1, it is characterised in that the condensed phosphate of (B) composition is pyrophosphoric acid Salt or tripolyphosphate.

3. Dentrifice composition according to claim 1 or 2, it is characterised in that (C) alpha-alkene sulfonate is carbon number 14~16 alpha-alkene sulfonate.

4. according to Dentrifice composition according to any one of claims 1 to 3, it is characterised in that (B)/(A) is by quality ratio For 0.005~50, and (C)/(A) is 0.05~100 by quality ratio.

5. according to Dentrifice composition according to any one of claims 1 to 4, it is characterised in that also containing (D) potassium nitrate 0.1~7 mass %.

6. according to Dentrifice composition according to any one of claims 1 to 5, it is characterised in that pH at 25 DEG C 5 with On.

7. according to Dentrifice composition according to any one of claims 1 to 6, it is characterised in that be modulated to toothpaste.

8. a kind of method that pH reductions suppressed in Dentrifice composition and metallic taste are presented, it is characterised in that containing (A) breast In the sour mass % of aluminium 0.01~5 Dentrifice composition, the addition mass % of (B) condensed phosphate 0.01~5 and (C) alpha-olefin sulphur The mass % of hydrochlorate 0.1~3.

9. the method that the pH reductions according to claim 8 suppressed in Dentrifice composition and metallic taste are presented, its feature It is, (B)/(A) is 0.005~50 by quality ratio, and (C)/(A) is 0.05~100 by quality ratio.

10. the method that the pH reductions suppressed in Dentrifice composition and metallic taste according to claim 8 or claim 9 is presented, its It is characterised by, the mass % of (D) potassium nitrate 0.1~7 is added also in Dentrifice composition.

11. the pH reductions suppressed in Dentrifice composition and metallic taste according to any one of claim 8~10 are presented Method, it is characterised in that pH of the Dentrifice composition at 25 DEG C is more than 5.

12. the pH reductions suppressed in Dentrifice composition and metallic taste according to any one of claim 8~11 are presented Method, it is characterised in that be modulated to toothpaste.