JP2000186092A - Ｕｃｎ−０１の製造法 - Google Patents

Ｕｃｎ−０１の製造法

Info

Publication number
JP2000186092A
JP2000186092A JP10364369A JP36436998A JP2000186092A JP 2000186092 A JP2000186092 A JP 2000186092A JP 10364369 A JP10364369 A JP 10364369A JP 36436998 A JP36436998 A JP 36436998A JP 2000186092 A JP2000186092 A JP 2000186092A
Authority
JP
Japan
Prior art keywords
ucn
acid
solution
formula
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP10364369A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000186092A5 (https=
Inventor
Akihito Nagamura
聡仁 長村
Hidenori Aoki
秀憲 青木
Mitsutaka Kino
光隆 城野
Toshimitsu Takiguchi
利光 滝口
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP10364369A priority Critical patent/JP2000186092A/ja
Priority to CA002293023A priority patent/CA2293023A1/en
Priority to US09/466,903 priority patent/US6197955B1/en
Priority to EP99125341A priority patent/EP1020471B1/en
Priority to AT99125341T priority patent/ATE241630T1/de
Priority to DE69908288T priority patent/DE69908288T2/de
Publication of JP2000186092A publication Critical patent/JP2000186092A/ja
Publication of JP2000186092A5 publication Critical patent/JP2000186092A5/ja
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP10364369A 1998-12-22 1998-12-22 Ｕｃｎ−０１の製造法 Abandoned JP2000186092A (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP10364369A JP2000186092A (ja) 1998-12-22 1998-12-22 Ｕｃｎ−０１の製造法
CA002293023A CA2293023A1 (en) 1998-12-22 1999-12-17 Process for producing ucn-01
US09/466,903 US6197955B1 (en) 1998-12-22 1999-12-20 Production of staurosporine derivative using acid isomerization
EP99125341A EP1020471B1 (en) 1998-12-22 1999-12-21 Process for producing UCN-01
AT99125341T ATE241630T1 (de) 1998-12-22 1999-12-21 Verfahren zur herstellung von ucn-01
DE69908288T DE69908288T2 (de) 1998-12-22 1999-12-21 Verfahren zur Herstellung von UCN-01

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10364369A JP2000186092A (ja) 1998-12-22 1998-12-22 Ｕｃｎ−０１の製造法

Publications (2)

Publication Number Publication Date
JP2000186092A true JP2000186092A (ja) 2000-07-04
JP2000186092A5 JP2000186092A5 (https=) 2005-07-28

Family

ID=18481646

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10364369A Abandoned JP2000186092A (ja) 1998-12-22 1998-12-22 Ｕｃｎ−０１の製造法

Country Status (6)

Country Link
US (1) US6197955B1 (https=)
EP (1) EP1020471B1 (https=)
JP (1) JP2000186092A (https=)
AT (1) ATE241630T1 (https=)
CA (1) CA2293023A1 (https=)
DE (1) DE69908288T2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887864B2 (en) 2002-03-12 2005-05-03 Hoffmann-La Roche Inc. Azepane derivatives
CA2532965C (en) 2003-07-22 2013-05-14 Astex Therapeutics Limited 3, 4-disubstituted 1h-pyrazole compounds and their use as cyclin dependent kinases (cdk) and glycogen synthase kinase-3 (gsk-3) modulators
AR054425A1 (es) 2005-01-21 2007-06-27 Astex Therapeutics Ltd Sales de adicion de piperidin 4-il- amida de acido 4-(2,6-dicloro-benzoilamino) 1h-pirazol-3-carboxilico.
US8404718B2 (en) 2005-01-21 2013-03-26 Astex Therapeutics Limited Combinations of pyrazole kinase inhibitors
MX2007008781A (es) * 2005-01-21 2007-09-11 Astex Therapeutics Ltd Compuestos farmaceuticos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62220196A (ja) 1986-03-20 1987-09-28 Kyowa Hakko Kogyo Co Ltd 新規物質ｕｃｎ―０１
EP0383919A4 (en) 1988-02-04 1992-08-05 Kyowa Hakko Kogyo Co., Ltd. Staurosporin derivatives
US5344926A (en) * 1992-06-22 1994-09-06 Kyowa Hakko Kogyo Co., Ltd. Process for producing staurosporine derivatives

Also Published As

Publication number Publication date
US6197955B1 (en) 2001-03-06
EP1020471A1 (en) 2000-07-19
CA2293023A1 (en) 2000-06-22
ATE241630T1 (de) 2003-06-15
DE69908288D1 (de) 2003-07-03
DE69908288T2 (de) 2004-04-08
EP1020471B1 (en) 2003-05-28

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